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Articles 511 - 540 of 5996
Full-Text Articles in Entire DC Network
Exploring Chronic Stress, Avoidance Coping, And Diurnal Cortisol In Head And Neck Cancer Patients: A Pilot Study Of Best Practices In Diurnal Cortisol Sampling., Brooks R. Harbison
Exploring Chronic Stress, Avoidance Coping, And Diurnal Cortisol In Head And Neck Cancer Patients: A Pilot Study Of Best Practices In Diurnal Cortisol Sampling., Brooks R. Harbison
Electronic Theses and Dissertations
Cancer patients are vulnerable to the deleterious effects of chronic stress, especially those prone to avoidance coping. Research in the general population has linked these effects to aberrant diurnal cortisol. However, the current literature on cancer patients has shown inconsistent results in associations between chronic stress, avoidance coping, and diurnal cortisol, possibly due to inconsistent cortisol sampling practices. This pilot study of head and neck cancer patients aimed to address this gap in the literature by implementing best cortisol sampling practices to investigate the links among chronic stress, avoidance coping, and diurnal cortisol slope, average bedtime cortisol, and average wake …
Derogatory, Racist, And Discriminatory Speech (Drds) In Video Gaming, Sean Woodford
Derogatory, Racist, And Discriminatory Speech (Drds) In Video Gaming, Sean Woodford
Dissertations
Video games have been examined for their effects on cognition, learning, health, and physiological arousal, yet research on social dynamics within video gaming is limited. Studies have documented the presence of derogation, racism, and discrimination in this anonymous medium. However, gamers‟ firsthand experiences are typically examined qualitatively. Thus, this study aimed to establish a quantitative baseline for the frequency of derogatory, racist, and discriminatory speech (DRDS) in gaming. DRDS frequency, sexual harassment, and hate speech measures were administered to 150 individuals from online forums and social media groups. Descriptive and inferential analyses were used to gauge which factors affected DRDS …
Optimization Of Mass Spectrometry-Based Methods For Low-Input And Spatial Proteomics, Andikan Jones Nwosu
Optimization Of Mass Spectrometry-Based Methods For Low-Input And Spatial Proteomics, Andikan Jones Nwosu
Theses and Dissertations
Eukaryotic cells are highly heterogeneous. These cells are arranged into different compartments, carrying out separate functions and facilitating biological processes. Proteins are the effector biomolecules targeted to subcellular locations that help fulfill specific tasks in living organisms. Spatial proteomics can help unravel molecularly how protein abundance and localization are altered in cells, which is not feasible in traditional bulk-scale proteomics. To achieve this, our lab has developed a miniaturized sample processing platform called nanoPOTS, reduced separation columns' inner diameter to increase ionization efficiency and concentrate analytes for mass spectrometers and optimized data acquisition modes for increasing proteome coverage in spatial …
The Protagonist Of Contemporary And Emerging Nanotechnology-Based Theranostics And Therapeutic Approaches In Reshaping Intensive Care Unit, Ling Xie, Yun Chen
The Protagonist Of Contemporary And Emerging Nanotechnology-Based Theranostics And Therapeutic Approaches In Reshaping Intensive Care Unit, Ling Xie, Yun Chen
Saudi Medical Journal
To maintain a clean and hygienic environment in the intensive care unit (ICU) is crucial for ensuring patient safety, preventing infections, and reducing healthcare-associated complications. With the increasing prevalence of infections and the emergence of viral and bacterial resistance to standard antiseptics, there is a pressing need for innovative antiseptic solutions. Nanotechnology is increasingly being employed in medicine, particularly focusing on mitigating the activities of various pathogens, including those associated with hospital-acquired infections. This paper explores the current impact of nanotechnology, with a particular focus on bacterial infections and SARS-CoV-2, which significantly strain healthcare systems, and then discusses how nanotechnology …
Placental Co-Transcriptional Activator Vestigial-Like 1 (Vgll1) Drives Tumorigenesis Via Increasing Transcription Of Proliferation And Invasion Genes, Heather Sonnemann
Placental Co-Transcriptional Activator Vestigial-Like 1 (Vgll1) Drives Tumorigenesis Via Increasing Transcription Of Proliferation And Invasion Genes, Heather Sonnemann
Dissertations and Theses (Open Access)
Vestigial-like 1 (VGLL1) is a co-transcriptional activator that binds to TEA domain containing transcription factors (TEADs). Its expression is upregulated in a variety of aggressive cancer types, including pancreatic and basal-like breast cancer, and increased transcription of VGLL1 is strongly correlated with poor prognosis and decreased overall patient survival. In normal tissues, VGLL1 is most highly expressed within placental trophoblast cells, which share the common attributes of rapid cellular proliferation and invasion with tumor cells. The impact of VGLL1 in cancer has not been fully elucidated and no VGLL1-targeted therapy currently exists. The aim of this study was to evaluate …
The Role Of An Ultraconserved Long Non-Coding Rna In B-Cell Lymphomagenesis, Swati Mohapatra
The Role Of An Ultraconserved Long Non-Coding Rna In B-Cell Lymphomagenesis, Swati Mohapatra
Dissertations and Theses (Open Access)
Ultraconserved regions (UCRs) are genomic segments with perfect (100%) conservation between the orthologous regions of human, rat, and mouse genomes. UCRs can be transcribed into mono-exonic long non-coding RNAs (lncRNAs) known as transcribed ultraconserved regions (T-UCRs). These regions, despite lacking protein-coding potential, are increasingly recognized for their regulatory roles in gene expression, including the modulation of non-coding RNA (ncRNA) transcripts. NcRNAs play crucial roles in cellular processes, including oncogenic transformation, with emerging evidence revealing their ability to encode small peptides known as ncRNA-encoded peptides (ncPEPs). These peptides, originating from small open reading frames (smORFs), contribute to diverse cellular functions and …
Predicting Individual Hiking Trail Intensity Using Statistical Learning, Kelci Hannan
Predicting Individual Hiking Trail Intensity Using Statistical Learning, Kelci Hannan
All Graduate Theses and Dissertations, Fall 2023 to Present
Hiking is an increasingly popular choice for people wanting to engage in recreation and physical activity. It not only offers the many benefits of exercise but also the opportunity to explore nature and to socialize. To ensure that new hikers are prepared to hike and remain safe while on the trail, knowledge of a hiking trail's difficulty is important. Trail difficulty information is sometimes available at the trailhead if the trail is well-trafficked and maintained but is nearly always available online or through a hiking-specific mobile application, such as AllTrails. Both trailhead and online sources provide only one difficulty rating …
Development Of 3d Human Cardiovascular And Cancer Tissue Model Within A Self-Driven Microfluidic Platform For Preclinical Drug Screening, Aibhlin Alexis Esparza
Development Of 3d Human Cardiovascular And Cancer Tissue Model Within A Self-Driven Microfluidic Platform For Preclinical Drug Screening, Aibhlin Alexis Esparza
Open Access Theses & Dissertations
According to the American Heart Association and World Health Organization, cardiovascular diseases (CVDs) are the leading cause of death worldwide. Monolayer cell culture (2D) and animal models are conventional methods to study CVDs, however, they limit researcherâ??s ability to simulate the human cardiovascular cellular microenvironments and accurate predication of pharmaceutical drug responses. Human induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs), biomaterials, and microfluidic technologies can be combined to create a controlled, reproducible 3D platform to study physiologically-relevant cellular responses to biochemical and physical changes in the microenvironment. My dissertation work demonstrates the development of novel self-driven microfluidic devices designed with …
Student Perceptions And Academic Performance When Taught With Multiple Active Learning Methods In A High Enrollment Undergraduate Human Physiology Course, Kate Ireton Walker
Student Perceptions And Academic Performance When Taught With Multiple Active Learning Methods In A High Enrollment Undergraduate Human Physiology Course, Kate Ireton Walker
Graduate Theses and Dissertations
When instructing very large groups of students in science, it can be difficult to engage all students in the content and measure their understanding. A major unaddressed challenge in science instruction is how specifically to design and implement strategies that engender active learning particularly in high-enrollment undergraduate courses. Active learning, which represents a diverse set of strategies, may include student engagement as part of instruction through discussions, active movement, and application (Bernstein, 2018; Cavanagh, et al. 2016; Michael, 2006 & Wilke, 2003). This study was designed to provide data addressing the gap in the literature regarding how the continual implementation …
The Effects Of Non-Invasive Brain Stimulation On Excitability Of The Primary Motor Cortices And Complex Motor Task Learning, Erik Woodruff Wilkins
The Effects Of Non-Invasive Brain Stimulation On Excitability Of The Primary Motor Cortices And Complex Motor Task Learning, Erik Woodruff Wilkins
UNLV Theses, Dissertations, Professional Papers, and Capstones
Transcranial direct current stimulation (tDCS) and transcranial alternating current stimulation (tACS) are promising non-invasive brain stimulation techniques, particularly for clinical applications involving altered or impaired motor function, such as in stroke and Parkinson’s disease. Although tDCS and tACS are different modalities, both forms of stimulation operate on the same principle - weak electrical currents are delivered through electrodes placed on the scalp in specific configurations known as “montages”. The most commonly used montage for targeting the primary motor cortex (M1) is the M1-SO configuration. This montage leverages the established observation that cortical regions directly beneath the anode generally increase in …
Effects Of Hypoxia On Monocyte Differentiation And Macrophage Specification During Ischemic Heart Injury, Farid Faridovich Kadyrov
Effects Of Hypoxia On Monocyte Differentiation And Macrophage Specification During Ischemic Heart Injury, Farid Faridovich Kadyrov
Arts & Sciences Graduate Student Theses and Dissertations
Myocardial infarction (MI) occurs following cessation of blood flow to an area of the heart and leads to ischemia, cardiomyocyte death, and inflammation. Chronically, MI initiates a compensatory process referred to as left ventricular remodeling, which is characterized by cardiomyocyte hypertrophy, fibrosis, and a decline in heart function. Left ventricular remodeling is central to the pathogenesis of heart failure. During myocardial infarction, Ly6chigh CCR2+ monocytes enter the heart and differentiate into a variety of macrophage populations including inflammatory CCR2+ macrophages. Resident cardiac macrophages are also present within the heart at homeostasis. Previous research from several groups has shown that once …
Systematic Review Of Factors Related To Pm2.5 Exposure On The Risk Of Type 2 Diabetes Mellitus, Rifka Putri Salma, Laila Fitria
Systematic Review Of Factors Related To Pm2.5 Exposure On The Risk Of Type 2 Diabetes Mellitus, Rifka Putri Salma, Laila Fitria
Kesmas
Diabetes mellitus is a major public health problem in many countries, and most of them are type 2 diabetes mellitus (T2DM). Air pollution is thought to contribute to the T2DM incidence, and one of the most important pollutants is PM2.5. This study aimed to determine factors related to PM2.5 exposure and individual factors in increasing the risk of T2DM based on a systematic review. The PRISMA was used as a method of data collection and selection. Of 176 relevant articles identified and screened, 12 articles from various countries published in 2013-2021 were synthesized in this study. Results showed that long-term …
Multimodal Cell Complex Neural Networks For Prediction Of Multiple Drug Side Effects Severity And Frequency, Mustafa Hajij, Ghada Alzamzmi, Nina Miolane
Multimodal Cell Complex Neural Networks For Prediction Of Multiple Drug Side Effects Severity And Frequency, Mustafa Hajij, Ghada Alzamzmi, Nina Miolane
USF Patents
A method for predicting side effects of a combination of drugs administered concurrently includes training a multi-modal cell complex neural network (MCXN) on a dataset. The MCXN includes nodes representing the drugs and proteins, pair-wise relationships between nodes representing interactions between pairs of drugs and/or proteins, and k-wise relationships between the nodes representing interactions between k drugs and/or proteins, where k¿2. The training dataset includes a list of drugs, a list of proteins, and pharmacological information about the drugs in the list of drugs and proteins in the list of proteins. A specification of the combination of at least three …
10-H2da Coating On Polyvinyl Chloride Catheter Biomaterials For Prevention Of Candida-Associated Urinary Tract Infections, Jermiah Tate
10-H2da Coating On Polyvinyl Chloride Catheter Biomaterials For Prevention Of Candida-Associated Urinary Tract Infections, Jermiah Tate
Electronic Theses and Dissertations Archive
Urinary catheters made of polyvinyl chloride (PVC) are susceptible to microbial biofilm formation. 10-hydroxy-2-decenoic acid (10-H2DA) is a dispersal signaling molecule that inhibits biofilm and planktonic growth of microorganisms. This study hypothesized that coating PVC with 10-H2DA would inhibit planktonic and biofilm-associated Candida albicans. Interactions of the PVC and 10-H2DA molecules were analyzed using Video Contact Angle (VCA), Fourier Transform Infrared (FTIR), and High-Performance Liquid Chromatography (HPLC). Successful coating of PVC with 10-H2DA was demonstrated through a significantly lowered contact angle and FTIR peaks in regions indicative of the 10-H2DA on the surface of PVC. Elution data displays a burst …
The Role Of Biological Plasticity In Model-Based Translational Research, Jessica A. Bolker
The Role Of Biological Plasticity In Model-Based Translational Research, Jessica A. Bolker
Faculty Publications
Reports of low replicability and translatability of biomedical research have called the value of animal models into question. The problems are real, but abandoning animal research is not the solution. Rather, improving the translatability of model-based research requires attention to relevant differences between humans and models, and to attributes of the models themselves that are essential to both robust science and effective translation. One is biological plasticity, the responsiveness of individual organisms to complex and variable environments. Though under-represented in model systems (for both historical and practical reasons), plasticity is central to human biology. While there are good reasons to …
Roles Of Hydrogen Sulfide (H2s) As A Potential Therapeutic Agent In Cardiovascular Diseases: A Narrative Review, Kazi N. Islam, Ivan D. Nguyen, Rahib Islam, Humza Pirzadah, Hassan Malik
Roles Of Hydrogen Sulfide (H2s) As A Potential Therapeutic Agent In Cardiovascular Diseases: A Narrative Review, Kazi N. Islam, Ivan D. Nguyen, Rahib Islam, Humza Pirzadah, Hassan Malik
School of Medicine Faculty Publications
Cardiovascular disease (CVD) stands as one of the leading causes of morbidity and mortality worldwide, and the continued search for novel therapeutics is vital for addressing this global health challenge. Over the past decade, hydrogen sulfide (H₂S) has garnered significant attention in the field of medical research, as it has been proven to be a cardioprotective gaseous signaling molecule. It joins nitric oxide and carbon monoxide as endogenously produced gasotransmitters. As for its mechanism, H₂S functions through the posttranslational addition of a sulfur group to cysteine residues on target proteins in a process called sulfhydration. As a result, the observed …
Provider Implementation Of Probiotics As An Adjuvant Treatment Modality For Patients With Anxiety And Or Depression In A Primary Care Setting, Sarah Dedmon
Doctoral Dissertations and Projects
The prevalence of anxiety and depression among Americans is growing rapidly. Patients are seeking out traditional treatments as offered by their primary care providers, but also frequently look toward integrative or complementary methods of managing their symptoms. The use of dietary supplements is at an all-time high, yet the U.S. Food and Drug Administration does not regulate these substances for potency and purity or evaluate them using quality standards as it does pharmaceuticals. Most providers lack education regarding the physiological interaction their patients may experience when using these substances and are naïve to their place in primary care medicine. The …
Effect Of Midsole Thickness On Running Economy, Comfort And Effort In Well-Trained Runners, Gian-Andri Baumann, Mattia Nolè, Christina M. Spengler, Fernando G. Beltrami
Effect Of Midsole Thickness On Running Economy, Comfort And Effort In Well-Trained Runners, Gian-Andri Baumann, Mattia Nolè, Christina M. Spengler, Fernando G. Beltrami
ISBS Proceedings Archive
By the current rules, midsoles in running shoes cannot exceed 40 mm in thickness, but this limit seems arbitrary. We investigated the effect of midsole thicknesses beyond the current limits on running economy, perceived comfort and effort, and spatiotemporal variables. Sixteen well-trained runners completed twelve outdoor runs (1.2 km each) at 16 km·h−1 alternating between three different footwear (one entry-level shoe (EL) with 30mm thickness and two modern shoes with thickness of 40 mm and 50 mm). Both modern shoes showed lower O2 uptake and effort compared with EL, but no differences between the 40-mm and 50-mm shoes …
“Sapere Aude!” (“Dare To Know!”): Learn To Teach Feminism, Rainier A. Ibana
“Sapere Aude!” (“Dare To Know!”): Learn To Teach Feminism, Rainier A. Ibana
Budhi: A Journal of Ideas and Culture
No abstract provided.
Genetic Diversity Of 1,845 Rhesus Macaques Improves Genetic Variation Interpretation And Identifies Disease Models, Jun Wang, Meng Wang, Ala Moshiri, R Alan Harris, Muthuswamy Raveendran, Tracy Nguyen, Soohyun Kim, Laura Young, Keqing Wang, Roger Wiseman, David H O'Connor, Zach Johnson, Melween Martinez, Michael J Montague, Ken Sayers, Martha Lyke, Eric Vallender, Tim Stout, Yumei Li, Sara M Thomasy, Jeffrey Rogers, Rui Chen
Genetic Diversity Of 1,845 Rhesus Macaques Improves Genetic Variation Interpretation And Identifies Disease Models, Jun Wang, Meng Wang, Ala Moshiri, R Alan Harris, Muthuswamy Raveendran, Tracy Nguyen, Soohyun Kim, Laura Young, Keqing Wang, Roger Wiseman, David H O'Connor, Zach Johnson, Melween Martinez, Michael J Montague, Ken Sayers, Martha Lyke, Eric Vallender, Tim Stout, Yumei Li, Sara M Thomasy, Jeffrey Rogers, Rui Chen
Faculty, Staff and Students Publications
Understanding and treating human diseases require valid animal models. Leveraging the genetic diversity in rhesus macaque populations across eight primate centers in the United States, we conduct targeted-sequencing on 1845 individuals for 374 genes linked to inherited human retinal and neurodevelopmental diseases. We identify over 47,000 single nucleotide variants, a substantial proportion of which are shared with human populations. By combining rhesus and human allele frequencies with established variant prediction methods, we develop a machine learning-based score that outperforms established methods in predicting missense variant pathogenicity. Remarkably, we find a marked number of loss-of-function variants and putative deleterious variants, which …
Towards An Interdisciplinary “Science Of The Mind”: A Call For Enhanced Collaboration Between Philosophy And Neuroscience, Alessandra Buccella, Uri Maoz, Liad Mudrik
Towards An Interdisciplinary “Science Of The Mind”: A Call For Enhanced Collaboration Between Philosophy And Neuroscience, Alessandra Buccella, Uri Maoz, Liad Mudrik
Psychology Faculty Articles and Research
In recent decades, the neuroscientific community has moved from describing the neural underpinnings of mental phenomena—as characterized by experimental psychology and philosophy of mind—to attempting to redefine those mental phenomena based on neural findings. Nowadays, many are intrigued by the idea that neuroscience might provide the “missing piece” that would allow philosophers (and, to an extent, psychologists, too) to make important advances, generating new means that these disciplines lack to close knowledge gaps and answer questions like “What is Free Will?” and “Do humans have it?.” In this paper, we argue that instead of striving for neuroscience to replace philosophy …
Majors And Minors, Saint Mary's College Of California
Majors And Minors, Saint Mary's College Of California
Undergraduate Academic Catalog
No abstract provided.
Identification Of Core Competencies For Exercise Oncology Professionals: A Delphi Study Of United States And Australian Participants, Mary A. Kennedy, Kelley Covington Wood, Anna Campbell, Melanie Potiaumpai, Christopher M. Wilson, Anna L. Schwartz, Jessica Gorzelitz, Maxime Caru, Kathryn H. Schmitz
Identification Of Core Competencies For Exercise Oncology Professionals: A Delphi Study Of United States And Australian Participants, Mary A. Kennedy, Kelley Covington Wood, Anna Campbell, Melanie Potiaumpai, Christopher M. Wilson, Anna L. Schwartz, Jessica Gorzelitz, Maxime Caru, Kathryn H. Schmitz
Research outputs 2022 to 2026
Introduction: Integration of exercise into standard oncology care requires a highly skilled workforce of exercise professionals; however, competency requirements have not kept pace with advancements in the field. Therefore, the aim of this study was to obtain consensus on core competencies required for an exercise professional to be qualified to work with adults undergoing active cancer treatment. Materials and Methods: A three-round modified electronic Delphi process was used. In Round 1, an international group of 64 exercise oncology stakeholders (i.e., exercise oncology professionals (n = 29), clinical referrers (n = 21), and people with lived experience (n = 14)) responded …
The Effect Of Angiogenesis On Thermal Properties Of In-Vivo Human Tissue, Shriya Musuku
The Effect Of Angiogenesis On Thermal Properties Of In-Vivo Human Tissue, Shriya Musuku
Theses
Bioheat transfer is the study of heat transfer in biology. There are several sources of heat in biology including external ones such as surgical applications of heat, or internal ones like cancer tissue. Blood flow networks affect both types of processes and are often generated during disease phenomenon through a process called angiogenesis. This affects the properties of the tissue. Several attempts were made to model flow and heat transfer within various tissues through physical measurements or computer simulations. Both types of models used bioheat transfer models do not consider the geometry of vasculature at its most fundamental level. The …
T. Boudieri Extract Potentiates The Effects Of Capecitabine Treatment In Human Colon Cancer Cells, Katia Sawaya, Mahmoud Khalil, Ghada Khawaja
T. Boudieri Extract Potentiates The Effects Of Capecitabine Treatment In Human Colon Cancer Cells, Katia Sawaya, Mahmoud Khalil, Ghada Khawaja
BAU Journal - Science and Technology
Resistance to chemotherapy remains a major challenge for colorectal cancer patients worldwide, hence the persistent need to uncover alternative treatments as well as new adjunct therapies in the fight against cancer. Natural extracts constitute an excellent source of bioactive substances that have a promising potential in that regard, with minimal negative side effects. We have previously demonstrated that both the ethanolic as well as the water extracts of Terfezia boudieri, a black desert truffle abundant in and part of the cuisine of the Mediterranean region, have significant antiproliferative effects against colon cancer cells. Our aim in this study was …
Communication Research On Sign Language Telecommunication And Digital Modes Of Interpretation., Scooter Briody
Communication Research On Sign Language Telecommunication And Digital Modes Of Interpretation., Scooter Briody
Honors Theses
Since the invention and proliferation of the telephone in the late nineteenth century, our world has become increasingly dependent on technologically mediated communication. Nowadays we are just as likely to have our next human interaction through our smartphone or computer screen as we are to meet another person face to face. We do not even tend to think of these things as tools for telecommunication anymore, but rather as extensions of our own will. Despite the overwhelming convenience of this technology, it is also fundamentally created with the interests of certain people in mind. If you are able to use …
Increasing Measurement Accuracy: Scaling Effect On Academic Resilience Instrument Using Method Of Successive Interval (Msi) And Method Of Summated Rating Scale (Msrs), Beta Wulan Febriana, Farida Agus Setiawati
Increasing Measurement Accuracy: Scaling Effect On Academic Resilience Instrument Using Method Of Successive Interval (Msi) And Method Of Summated Rating Scale (Msrs), Beta Wulan Febriana, Farida Agus Setiawati
Jurnal Penelitian dan Evaluasi Pendidikan
A research instrument is crucial and must meet the requirements to be valid and reliable in content and construction. Not infrequently, various methods are tried to increase the accuracy of research instruments, one of them being a simple method such as the scaling technique. This research aims to improve measurement accuracy by using scaling techniques through the process of successive intervals and summated rating scale in confirmatory factor analysis of the Academic Resilience (ARS) instrument. This research is a descriptive exploratory study using a questionnaire consisting of five answer choices (5-point Likert scale) as the research instrument. Participants in this …
Assessing Human Visual Attention In Retail Human-Robot Interaction: A Yolov8-Nano And Eye-Tracking Approach, Kamlesh Kumar, Yuhao Chen, Boyi Hu, Yue Luo
Assessing Human Visual Attention In Retail Human-Robot Interaction: A Yolov8-Nano And Eye-Tracking Approach, Kamlesh Kumar, Yuhao Chen, Boyi Hu, Yue Luo
Faculty Research, Scholarly, and Creative Activity
Objectives: This research delves into the dynamics of human-robot interaction (HRI) in retail environments, with a focus on robot detection from videos captured via an eye-tracking system. Methods: The study employs YOLOv8-nano model for real-time robot detection during grocery shopping tasks. All videos were processed using the YOLOv8 model to test inference speed while performing eye-tracking data analysis as a case study. Results: The YOLOv8 model demonstrated high precision in robot detection, with a mean average precision (mAP) of approximately 97.3% for Intersection over Union (IoU), 100% precision, and 99.87% recall for box detection. The model's ability to process an …
The Other Arctic: Competition, Cooperation, Or Coexistence?, John B. Kelley, Christopher J. Sarton, Scott A. Curtice, Charles C. York Iii
The Other Arctic: Competition, Cooperation, Or Coexistence?, John B. Kelley, Christopher J. Sarton, Scott A. Curtice, Charles C. York Iii
Joint Force Quarterly
In Antarctica, the United States must mitigate risks stemming from competitive influences working to alter the current paradigms, but it also should seize the opportunities that Antarctica’s unique status affords. As climate change continues to open new opportunities in polar regions, international concern has grown over the potential for the future irresponsible use of the area by actors more concerned with military and economic advantage than conservation efforts. Apprehension over the People’s Republic of China (PRC)’s activities raises more significant concerns that Antarctica may become a region of military competition instead of global cooperation. This apprehension is well-founded but not …
Case Report: Dementia Sensitivity To Altitude Changes And Effective Treatment With Hyperbaric Air And Glutathione Precursors, Edward F. Fogarty, Paul G. Harch
Case Report: Dementia Sensitivity To Altitude Changes And Effective Treatment With Hyperbaric Air And Glutathione Precursors, Edward F. Fogarty, Paul G. Harch
School of Medicine Faculty Publications
A 78-year-old man with dementia experienced waxing and waning of symptoms with changes in altitude as he traveled from his home in the Rocky Mountains to lower elevations and back. To replicate the improvement in his symptoms with travel to lower elevations (higher pressure), the patient was treated with a near-identical repressurization in a hyperbaric chamber using compressed air. With four 1-h treatments at 1.3 Atmospheres Absolute (ATA) and concurrent administration of low-dose oral glutathione amino acid precursors, he recovered speech and showed improvement in activities of daily living. Regional broadcast media had documented his novel recovery. Nosocomial COVID-19 and …