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In Vitro Resorption Characteristics Of Selected Diuretic Compounds By Thedesaga Resomat, Donald Gene Floriddia

University of the Pacific Theses and Dissertations

An in vitro method was tested whereby the processes of dissolution and distribution of active ingredient into a lipoid solvent were combined in one model and evaluated.

The objectives of this research project were: (1) to evaluate the efficacy of the in vitro model known as the Desaga Resomat, in the testing of gastrointestinal absorption; (2) to apply the procedure and instrument to a group of therapeutically important products in determining their absorption characteristics; (3) to graphically illustrate the absorption profile of a specific drug as per cent absorbed vs. time, simulating in vivo absorption; (4) to compare the profile …

Faculty Publications July 1969 - June 1970, Lsu Health Sciences Center New Orleans

Historical Faculty Publications

This Faculty bibliography contains 164 publications.

End Matter, Vol. 12 No. 3

Brigham Young University Science Bulletin, Biological Series

No abstract provided.

Differential Effects Of Various Language Sampling Procedures On Children's Verbal Output, Wanda G. Webb

Masters Theses

The purpose of this investigation was to determine whether differences exist among four dlfferent language sampling procedures as to measures of communicative competence. Specifically, three questions were posed:

1. Do statistically significant differences exist among obtained LCI scores for the following procedures for evoking child language samples: (1) Toys, (2) Verbal Directives, (3) Child-generated Pictures, and (4) Radio Telemetry.
2. If differences exist, are they manifested in: (1) Noun Phrase One, (2) Verb Phrase One, (3) Noun Phrase Two.
3. What is the frequency of occurrence of the obtained grammatical structures for the sampling procedure yielding the highest LCI scores?

PROCEDURE. Four language …

The Immediate Effect Of Swimming And Track Competition On Blood Ph Values, James B. Knott

Masters Theses

The purpose of the study was to investigate the changes associated with blood pH and different exercise work loads during competition. Finger tip blood samples (1 milliliter), were obtained from 33 male subjects from the varsity swimming and track teams of Eastern Illinois University. The samples were taken prior to exercise and between three and seven and one half minutes after cessation of the event. The blood samples were analyzed with a Radiometer Micro Blood pH Unit. The subjects were chosen on the basis of the events in which they competed. The swimming subjects competed in the 100, 200, 500, …

Label Uptake In Maternal And Fetal A/Jax Mouse Tissues After Maternal Injections Of Tritiated Cortisol: A Liquid Scintillation Study, Gilbert E. Dodds

Master's Theses

No abstract provided.

A Retrospective Study Of Drug Interactions And Their Clinical Significance In 100 Hospitalized Patients, Michael Ray Alexander

University of the Pacific Theses and Dissertations

Within the past several years, a great deal of attention has been focused on the phenomena of drug-drug interactions and their importance in the therapeutic regimen of patients for whom multiple therapeutic agents might be indicated. The rather sudden concern for this aspect of medical and pharmaceutical practice is evidenced by the proliferation of literature devoted to the topic for both professions. While iatrogenic disease has long been recognized as one of the hazards inherent in prescribing practices, only isolated reports of specific interactions were found until recently. Although it cannot be said with certainty when the first interaction of …

A Pharmacologic Investigation Of The Antiinflammatory Activity Of Cryogenine, Donald Saadia Kosersky

University of the Pacific Theses and Dissertations

This study was conducted in an attempt to define the anti inflammatory efficacy of cryogenine, the major alkaloid of Heimia salicifolia Link and Otto. The anti inflammatory effects produced by cryogenine, phenylbutazone, indomethacin, mefenamic acid, paramethasone, hydrocortisone and 6-mercaptopurine were compared considering the sequential changes in various motameters during the course of adjuvant-induced polyarthritis in rats. Polyarthritis was induced by the subplantar injection of a suspension of heat-killed Mycobacterium butyricus in mineral oil into the right hind paw of Sprague-Dawley rats. The manifestations of the diseases were monitored in terms of hind paw swelling, subjective appearance of secondary lesions, impairment …

Antibradykinin Evaluation Of Cryogenine And Selected Other Agents, Ralph William Trottier Jr.

University of the Pacific Theses and Dissertations

One intent of this study was to detect and to define any antibradykinin capacity that cryogenine may have using both in vivo and in vitro pharmacological models. The activity of cryogenine in these tests was compared to a variety of clinically-proven anti-inflammatory compounds as well as to other agents known to possess anti-inflammatory activity in certain experimentally-induced inflammations. Cryogenine is an unusual anti-inflammatory agent since it is an alkaloid - all of the commonly used anti-inflammatories (aspirin, phenylbutazone, indomethacin, etc.) are organic acids.

The Effects Of Indomethacin On A Strain Of Fibroblasts Cultivated In Vitro, John Thomas Mccloskey

University of the Pacific Theses and Dissertations

Man has always searched for greater understanding of himself and his environment. As a result, much scientific investigation has been directed towards the understanding of the life process. In recent years, such scientific inquiry has become increasingly focused on the fundamental biochemical events taking place at the cellular, subcellular, and molecular levels. In the course of investigation into the nature of living things, research has often necessitated the development of new techniques and investigational tools to serve as experimental systems. Very often such new methods have made possible the discovery of previously unknown processes. One very interesting and useful investigational …

The Dialysis Of Caffeine Through Selected Semi-Permeable Membranes, Paul James Perry

University of the Pacific Theses and Dissertations

Until the past few years, cellulose derivatives, (e.g., cellophane, collodion, and parchment) and animal membranes (e.g., goldbeater’s skin) have been the only dialysis membranes employed commercially. Cellophane has been used as the dialysis membrane in the artificial kidney since the machine’s inception in 1914. It continues to serve in this capacity, even though, in the last few years, attempts have been made to develop better films.

An appreciation of both the “solution theory” and the “pore theory” is in order for this discussion. By incorporating the dynamics of these theories in the techniques of membram formulation, improved membrane performance can …

Physiology Of A Uv-Induced, Coagulase-Positive, Avirulent Mutant Of Staphylococcus Aurues As Compared To Its Virulent Parent, James J. Bertucci

Master's Theses

No abstract provided.

The Cortical Nucleus Of The Amygdala As A Component In The Systems Regulating Gonadotrophin Secretion, Stuart Warren Smith

Dissertations

No abstract provided.

Radioautographic Incorporation Of Tritiated Lysine Into Protein Of Cells Of The Spermatogenic Cycle, Casimir F. Firlit

Dissertations

No abstract provided.

Hormonally-Induced Permeability Changes In Staphylococcus Aureus, Thomas J. Fitzgerald

Dissertations

No abstract provided.

Neurochemical Evidence For Cholinergic-Adrenergic Coupling In Mammalian Central Nervous System, Silas N. Glisson Iii

Dissertations

No abstract provided.

Investigation Of The Anticurare Effect Of Sodium Fluoride At The Mammalian Skeletal Neuromuscular Junction: A Dissertation, Robert S. Jacobs

Dissertations

No abstract provided.

Histochemical Localization And Identification Of Monoamine-Containing Cell Bodies In The Brain Stem Of The Squirrel Monkey (Saimiri Sciureus), Jack E. Hubbard

Dissertations

No abstract provided.

Protein Synthesis In Regenerating Wound Tissue And The Effect Of Thyroid Hormone, Cary Bruce Linksy

Dissertations

No abstract provided.

The Interaction Of Ethidium Bromide With Nucleic Acids, William Warren Martz

Dissertations

No abstract provided.

Glutaraldehyde As A Cold Sterilizing Agent For Endodontic Instruments, Gary Max Ritchie

Master's Theses

No abstract provided.

The Effects Of Various Cation Concentrations On Salivary Amylase Activity, William Macdonald Reeves

Master's Theses

No abstract provided.

Correlations Between Behavioral Changes And Drug Induced Variations Of The Levels Of Mouse Brain Catecholamines And Serotonin, Daniel Leo Richardson

Master's Theses

No abstract provided.

Dentofacial Changes Of The Pre-Adolescent Child Produced By Heavy, Continuous Posterior Traction To The Maxillary Molars, Parallel To The Occlusal Plane: A Serial Cephalometric Investigation, Norman Lewis Sanders

Master's Theses

No abstract provided.

Circadian Rhythm In The Labial Gingival Epithelium Of The Rat Maxillary Incisor, Paul A. Stutman

Master's Theses

No abstract provided.

Effect Of Vitamin D On Ribonucleic Acid Synthesis In Bone, Sue Ann Eckhardt Shelley

Master's Theses

No abstract provided.

A Morphologic Comparison Of The Periodontal Ligament Of Normal Versus Accelerated Erupting Teeth In Rats And Guinea Pigs, Andrew P. Trapani

Master's Theses

No abstract provided.

Effect Of Niacin And Its Analogs On Growth And On The Glucose Catabolic Pathways Of Staphylococcus Aureus, Manohar V. Wadke

Master's Theses

No abstract provided.

Transformation And Transfection In Mycobacterium, Louis A. Desalle

Master's Theses

No abstract provided.

The Intracanal Diffusion Of Camphorated Para-Mono-Chlorophenol In Endodontics: An Autoradiographic Study, Gerald R. Heiman

Master's Theses

No abstract provided.