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Passage Or Pathology: Current Attitudes Toward Women's Aging In The Literature Of Menopause, Kaaren Gearhart Ancarrow

Institute for the Humanities Theses

Menopause is currently portrayed in the medical literature as a pathological 11 process resulting from "hormone deficiency." However, feminist writers contend that the climacteric is part of the normal female aging process and oppose the medicalization of menopause and the consequent inevitable hormone replacement therapy (HR T) promoted by the hegemonic medical and pharmaceutical industries. This paper explores the historical development of these two paradigms of menopause and their manifestations in samples of three classes of contemporary literature on the subject: gynecological textbooks, popular advice books written by physicians, and women's accounts. Five major themes are investigated using quantitative and …

What's Happening: September 4, 1996, Maine Medical Center

What's Happening

No abstract provided.

Use Of L-Canavanine As A Chemotherapeutic Agent For The Treatment Of Pancreatic Cancer, Peter Crooks, Gerald A. Rosenthal

Pharmaceutical Sciences Faculty Patents

A pharmaceutical composition of canavanine, and a method treatment of cancer, particularly pancreatic cancer with L-canavanine is disclosed.

Current Issues In Rabies Prevention In The United States: Health Dilemmas, Public Coffers, Private Interests, Charles E. Rupprecht, Jean S. Smith, John Krebs, Michael Niezgoda, James E. Childs

Zoonotics and Wildlife Disease: Publications

Over the last 100 years, rabies in the United States has changed dramati~ally. More than 90% of all animal rabies cases reported annually to the CDC now occur in wildlife, whereas before 1960 the majority were in domestic animals. The principal rabies hosts today are wild carnivores and bats infected with several viral variants. Annual human deaths have fallen from more than a hundred at the turn of the century to one to two per year despite major outbreaks of animal rabies in several geographic areas. Modem day prophylaxis has proven nearly 100% successful; most human fatalities now occur in …

The Protective Role Of Manganese Superoxide Dismutase Against Adriamycin-Induced Acute Cardiac Toxicity In Transgenic Mice, Hsiu-Chuan Yen, Terry D. Oberley, Satit Vichitbandha, Ye-Shih Ho, Daret K. St. Clair

Toxicology and Cancer Biology Faculty Publications

Adriamycin (ADR) is a potent anticancer drug known to cause severe cardiac toxicity. Although ADR generates free radicals, the role of free radicals in the development of cardiac toxicity and the intracellular target for ADR-induced cardiac toxicity are still not well understood. We produced three transgenic mice lines expressing increased levels of human manganese superoxide dismutase (MnSOD), a mitochondrial enzyme, as an animal model to investigate the role of ADR-mediated free radical generation in mitochondria. The human MnSOD was expressed, functionally active, and properly transported into mitochondria in the heart of transgenic mice. The levels of copper-zinc SOD, catalase, and …

Vol. 19 No. 3 (1996): Pacific Studies Full Issue, The Jonathan Nāpela Center For Hawaiian And Pacific Islands Studies

Pacific Studies

Pacific Studies is published two times a year by The Jonathan Nāpela Center for Hawaiian and Pacific Studies, Brigham Young University Hawai‘i #1979, 55–220 Kulanui Street, Lāʻie, Hawai‘i 96762, but responsibility for opinions expressed in the articles rests with the authors alone. Subscription rate is US$40.00 yearly, payable to The Jonathan Nāpela Center for Hawaiian and Pacific Studies. The Jonathan Nāpela Center for Hawaiian and Pacific Studies (formerly The Pacific Institute) is an organization funded by Brigham Young University Hawai‘i. The Center assists the University in meeting its cultural and educational goals by undertaking a program of teaching, research, and …

Prevalence Of Antibodies To Feline Parvovirus, Calicivirus, Herpesvirus, Coronavirus, And Immunodeficiency Virus And Of Feline Leukemia Virus Antigen And The Interrelationship Of These Viral Infections In Free-Ranging Lions In East Africa, Regina Hofmann-Lehmann, Daniela Fehr, Markus Grob, Muhamed Elgizoli, Craig Packer, Janice S. Martenson, Stephen J. O'Brien, Hans Lutz

Biology Faculty Articles

While viral infections and their impact are well studied in domestic cats, only limited information is available on their occurrence in free-ranging lions. The goals of the present study were (i) to investigate the prevalence of antibodies to feline calicivirus (FCV), herpesvirus (FHV), coronavirus (FCoV), parvovirus (FPV), and immunodeficiency virus (FIV) and of feline leukemia virus (FeLV) antigen in 311 serum samples collected between 1984 and 1991 from lions inhabiting Tanzania’s national parks and (ii) to evaluate the possible biological importance and the interrelationship of these viral infections. Antibodies to FCV, never reported previously in free-ranging lions, were detected in …

Between Pets And People: The Importance Of Animal Companionship, Alan M. Beck, Aaron Katcher

New Directions in the Human-Animal Bond

Pets play a greater role in our emotional and physical health than ever before, says the Purdue University professor who is co-author of his revised edition of Between Pets and People: The Importance of Animal Companionship. The book offers conclusive evidence from the two foremost researchers in the field, Alan M. Beck and Aaron H. Katcher, that animals have a significant influence on human life and health. Dealing with such varied topics as pet ownership and gender differences, the pet’s freedom from social taboos, and pets’ taking on roles of family members, the authors show that animal companionship affects, …

Pregnancy Induced Hypertension--Anaesthetic Considerations, N A. Zubair

Department of Anaesthesia

No abstract provided.

Identification And Characterization Of The Thrombin Binding Sites On Fibrin, David A. Meh, Kevin R. Siebenlist, Michael W. Mosesson

Biomedical Sciences Faculty Research and Publications

Thrombin binds to fibrin at two classes of non-substrate sites, one of high affinity and the other of low affinity. We investigated the location of these thrombin binding sites by assessing the binding of thrombin to fibrin lacking or containing γ′ chains, which are fibrinogen γ chain variants that contain a highly anionic carboxyl-terminal sequence. We found the high affinity thrombin binding site to be located exclusively in D domains on γ′ chains (K_a, 4.9 × 10⁶⁻¹; n, 1.05 per γ′ chain), whereas the low affinity thrombin binding site was in the fibrin E …

Jefferson Alumni Bulletin – Volume Xlv, Number 4, September 1996

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XLV, Number 4, September 1996

Commencement Addresses, Page 4

Clinic Presentations, Page 8

Annual Giving, Page 27

Bookstore, Page 54

Intestinal Lesions Caused By Two Swine Chlamydial Isolates In Gnotobiotic Pigs, Douglas G. Rogers, Arthur A. Andersen

School of Veterinary and Biomedical Sciences: Faculty Publications

The objective of this study was to determine whether 2 distinct chlamydial isolates recovered from the intestines and feces of diarrheic nursery pigs could cause intestinal lesions in gnotobiotic pigs. Both isolates share biological characteristics with Chlamydia trachomatis. Chlamydial isolates R27 and R19 were propagated in Vero cells or embryonated eggs, respectively, and suspended in sucrose-phosphate-glutamine buffer with 10% fetal bovine serum for inoculation. Sham inocula were prepared from uninfected cell culture lysates and from uninfected eggs. Each piglet was fed 1 ml of inoculum or sham inoculum at 3-4 days of age. Ten piglets were each fed 10 …

Lung And Nasal Lesions Caused By A Swine Chlamydial Isolate In Gnotobiotic Pigs, Douglas G. Rogers, Arthur A. Andersen, Breck D. Hunsaker

School of Veterinary and Biomedical Sciences: Faculty Publications

The objective of this study was to determine whether a chlamydial isolate recovered from nasal swabs from swine with pneumonia could cause pneumonia and rhinitis in gnotobiotic pigs. The identity of the isolate currently is unknown, but it shares characteristics with Chlamydia trachomatis. After propagation in Vero cells and preparation of the inoculum (2.5 x 1010 inclusion-forming units/ml), Chlamydiae were instilled into nostrils (1.0 ml/nostril) and lungs (2.0 ml intralaryngeally) of 15 anesthetized 3-day-old gnotobiotic piglets. Five age-matched gnotobiotic piglets were anesthetized and sham infected with uninfected cell culture lysates. Two treated piglets were moribund and 2 were severely …

Efficient Vasoactive Intestinal Polypeptide Hydrolyzing Autoantibody Light Chains Selected By Phage Display, Sonia Tyutyulkova, Qing-Sheng Gao, Austin Thompson, Stephen I. Rennard, Sudhir Paul

Journal Articles: Pulmonary & Critical Care Med

An immunoglobulin light chain (L chain) library derived from the peripheral blood lymphocytes of a patient with asthma was cloned into a phagemid vector. Phage particles displaying L chains capable of binding vasoactive intestinal polypeptide (VIP) were isolated by affinity chromatography. Two VIP binding L chains were expressed in Escherichia coli in soluble form and purified to electrophoretic homogeneity by metal chelating and protein L affinity chromatography. Both L chains catalyzed the hydrolysis of [tyr10-125I]VIP substrate. The catalytic activity eluted at the molecular mass of the monomer form of the L chain (28 kDa) from a gel filtration column. The …

Health Promotion Practices Of Nurse Practitioners Practicing In The State Of Mississippi, Valerie O'Briant Sullivan

MSN Research Projects

Health promotion has become a major factor in the practice of modern medicine for reasons such as cost effectiveness, disease prevention, and health promotion. Nurse practitioners are on the forefront in educating the public about health promotion practices. The purpose of this study was to describe the health promotion practices of nurse practitioners who practice in the state of Mississippi. Pender's (1992) Health Promotion Model which uses wellness orientation guided the research. The study addressed the question: What are the health promotion practices of nurse practitioners who practice in the state of Mississippi? The sample was comprised of all nurse …

Dentalgram - Vol. 10, No. 08, Loma Linda University School Of Dentistry

Dentalgram

In this issue:

• Dr. Caruso chairs orthodontics
• Dr. Golden joins restorative
• Careers workshop held
• Klooster endowment
• Ricketts Resource Library dedicated
• Tooth models donated
• Amazon adventure
• Dental hygiene officers
• Nepal report
• Associate marshals named
• Employee of the Quarter

The Effects Of Lead Acetate On Host Susceptibility To Trypanosoma Cruzi, Tabitha Ellis

Masters Theses & Specialist Projects

Trypanosoma cruzi. a protozoan parasite, causes American trypanosomiasis or Chagas' disease. The infective stage of this parasite resides in the hindgut of the reduviid bug (family Reduviidae), which is both host and vector, and is transmitted to the mammalian host through fecal material released during a blood meal. Chagas' disease, an acute to chronic infection resulting in fever, malaise, and heart and liver enlargement, is becoming a concern in the United States due to the large increase in Latin American immigrants, and the lack of safe and effective therapeutic treatment and vaccination. Another growing concern in the United States involves …

Antibody Response To Heat Shock Proteins Of Trypanosoma Cruzi And Histopathology In Mice Infected And Maintained At Elevated Environmental Temperature, Ahmed Arif

Masters Theses & Specialist Projects

Trypanosoma cruzi is an obligate intracellular parasite infecting 18-20 million people in Latin America. It is the causative agent of Chagas' disease, commonly referred to as American Trypanosomiasis. The C3H murine model is widely used to study experimental Chagas' disease. It is well documented that when these highly susceptible mice are infected with the Brazil strain of T. cruzi and maintained at room temperature (RT), mice die between day 35-45 of infection. However, when held at an elevated temperature of 36°C, C3H mice survive an otherwise lethal infection with T. cruzi. When held at 36°C, the body temperature of the …

An Investigation Of Hexatylis Contracta Blomquist (Southern Heartleaf): Individuals, Hybrids, Populations And Species, Patrick Carroll

Masters Theses & Specialist Projects

Hexastylis contracta Blomquist is a rare herbaceous perennial plant endemic to southeastern North America. The plant exhibits a disjunct distribution, being found on the Cumberland Plateau of Tennessee and Kentucky and also 300 km east in the Blue Ridge Mountains of North Carolina. This plant was the subject of a population inventory supported through the Kentucky State Nature Preserves Commission (KNPC) which expanded the number of known populations of the species (28) by 68%, with 47 populations now known to exist. A morphological analysis of this species was done using principal components analysis. This analysis was used to answer questions …

The Significance Of The Therapeutic Use Of Pets On Socialization With Elders In An Extended Care Facility, Lisa Byrd

MSN Research Projects

In the year 2020, 80% of the United States population will be over the age of 65 years (Fick, 1993). Elders frequently reside in extended care facilities and experience feelings of loneliness, depression, disorientation, and helplessness (McQuillen, 1985). The therapeutic use of pets has been shown to have positive effects on the socialization of elders. Most research has been conducted utilizing group therapy with a pet. This study focused on the benefits of therapeutic use of pets with the individual elder. The theoretical framework was based on the Neuman Systems Model. The purpose of this study was to determine the …

Health Promotion Practices Of Nurse Practitioners Practicing In The State Of Mississippi, Valerie O-Briant Sullivan

MSN Research Projects

The purpose of this study was to describe the health promotion practices of nurse practitioners who practice in the state of Mississippi.

Effects Of Exercise And Psychosocial Stress On Blood Glucose In Non-Insulin Dependent Diabetics, Lisa Renae Clemensen

Dissertations

Non-insulin dependent diabetes often has serious consequences for individuals if blood glucose is not maintained within relatively normal ranges. Exercise and stress have been enumerated as important variables for the control of blood glucose in non-insulin dependent diabetics.

This study compared blood glucose and stress for eight exercise and eight matched control non-exercise adult noninsulin dependent participants. A prospective home monitoring design was used to monitor daily blood glucose, stress, and physical activity via multiple measures for six days.

Results indicated that control participants had significantly higher average blood glucose readings and higher blood glucose variability. Daily stress measures did …

Training Nonconventional Autoclitic And Tact Relationships In Children, Ingolfur Bergsteinsson

Dissertations

To some extent, one understands a complex aspect of human language if one can produce that kind of language in children who have not already acquired it. Skinner’s (1957) concept of autoclitic secondary verbal behavior is the most complex of his various verbal units, and until recently has not been the subject of experimental analysis. Howard and Rice (1988) made the first attempt to generate an autoclitic repertoire in preschool children, and the present study is an attempt to corroborate and extend their findings. They worked with the autoclitic “like” which identifies the accompanying primary verbal behavior as a form …

An Animal Model For Development Of Pulpal Inflammation, John W. Masters

Loma Linda University Electronic Theses, Dissertations & Projects

Several animal models have been proposed to develop pulpal inflammation. Procedures recommended in these models have many variables and have not produced consistent results. The purpose of this study was to create pulpal inflammation using the Nd:YAG laser.

Forty-five cuspids of 12-18 month old beagle dogs were lased at 5, 7.5, and 10 watts (W) for 20 seconds with a 600 micron contact probe. Five cuspids were not lased but were used as controls. Following laser application, the teeth were extracted at intervals of 3, 7, and 30 days. They were then fixed in 10% formalin, decalcified, sectioned, and stained …

Interleukin-10 Inhibits Tumor Metastasis Through An Nk-Cell Dependent Mechanism, Li-Mou Zheng, David M. Ojcius, F. Garaud, C. Roth, E. Maxwell, Z. Li, H. Rong, J. Chen, X. Y. Wang, J. J. Catino, I. King

All Dugoni School of Dentistry Faculty Articles

Interleukin-10 (IL-10) is a recently described pleiotropic cytokine secreted mainly by type 2 helper T cells. Previous studies have shown that IL-10 suppresses cytokine expression by natural killer (NK) and type 1 T cells, thus down-regulating cell-mediated immunity and stimulating humoral responses. We here report that injected IL-10 protein is an efficient inhibitor of tumor metastasis in experimental (B16-F10) and spontaneous (M27 and Lox human melanoma) metastasis models in vivo at doses that do not have toxic effects on normal or cancer cells. Histological characterization after IL-10 treatment confirmed the absence of CD8+ and CD4+ T cells and macrophages at …

Human Immunodeficiency Virus (Hiv)/Hepatitis B Virus (Hbv) Risk Perception Related To Needlestick Injuries At A Medical School In Norfolk, Virginia, Ronald B. Hartman

Community & Environmental Health Theses & Dissertations

A limited number of studies have been conducted to assess the perceptions of risk of medical students and residents for acquiring Human Immunodeficiency Virus (HIV) or Hepatitis B Virus (HBV) via percutaneous (needlestick) injuries while performing clinical training. The purpose of this study is to investigate these perceptions of risk, and to determine whether there is an association between a high perception of risk and a low incidence of needlestick injury. The method of investigation was a four-page survey questionnaire. The instrument was investigated for reliability by use of a pilot study with a small group of medical students and …

Low Molecular Weight Thiocarbamates As Inhibitors Of Elastase, Uses And Method Of Synthesis, George Digenis, Nikolaos P. Rodis

Pharmaceutical Sciences Faculty Patents

To see this abstract, please download this patent.

In The Affirmative, Vol.3, No.4 (Mid-July/Mid-August 1996), Mike Martin, The Aids Project

In the affirmative (1993-1999)

No abstract provided.

Cloning Of The Mammalian Type Ii Iodothyronine Deiodinase. A Selenoprotein Differentially Expressed And Regulated In Human And Rat Brain And Other Tissues., Walburga Croteau, Jennifer C. Davey, Valerie Anne Galton, Donald L. St Germain

Dartmouth Scholarship

The deiodination of thyroid hormones in extrathyroidal tissues plays an important role in modulating thyroid hormone action. The type II deiodinase (DII) converts thyroxine to the active hormone 3,5,3'-triiodothyronine, and in the rat is expressed in the brain, pituitary gland, and brown adipose tissue (BAT). Complementary DNAs (cDNAs) for the types I and III deiodinases (DI and DIII, respectively) have been isolated and shown to code for selenoproteins. However, information concerning the structure of the mammalian DII remains limited, and the pattern of its expression in human tissues is undefined. We report herein the identification and characterization of rat and …

What's Happening: July 10, 1996, Maine Medical Center

What's Happening

No abstract provided.