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Immune Responses To Final Exams In Healthy And Asthmatic Adolescents, Duck-Hee Kang, Christopher L. Coe, Donna O. Mccarthy, William B. Ershler

College of Nursing Faculty Research and Publications

Immune responses to an academic stressor were examined in healthy and asthmatic adolescents with regard to their illness symptom reports. Eighty-seven high school students completed a health diary for 2 weeks and provided three blood samples during midsemester, final-exam, and postexam periods. During exam week, all students showed significant immunological alterations from baseline: Natural killer cell activity was significantly lower, whereas lymphocyte proliferation and neutrophil superoxide release were significantly higher. These immune changes tended to return toward baseline during the postexam period, but the enhanced neutrophil reactivity continued to rise. Overall, immunological responses were similar between asthmatic subjects and controls. …

Faculty Publications 1996, Lsu Health Sciences Center New Orleans

Historical Faculty Publications

This Faculty bibliography contains 734 publications.

Living With Mental Illness: A Descriptive Study Of Individual Adult Experiences Of Living With Mental Illness In Zomba, Malawi, Ivy J. Lekera

Theses: Doctorates and Masters

The purpose of this study was to examine the experiences of mental illness in the adult Malawian context. Using the interpretive paradigm, content analysis was used to uncover the lived experiences of mental illness. This study was based on the philosophy that meaning of a phenomenon is best understood if studied within its specific context and within Parse's theoretical framework. Two to four per cent of the global population share the experience of mental illness, however, little is known of individual experiences within the Malawian context. Much of the literature has focused on the physiological aspects, causes, and therapies involved …

The Effects Of Concurrent Strength And Muscular Endurance Resistance Training On Strength, Endurance And Body Composition In Previously Untrained Females, Derek W. Gibbins

Theses : Honours

The number of females engaged in some form of sporting activity is growing rapidly, but many women still shy away from weight training because of their fear of excessive muscular hypertrophy and its accompanying loss of femininity. Because strength and muscular endurance play a vital role in most sporting endeavours, and weight training has proven to be one of the most effective methods to improve both attributes, any training regime that could achieve concurrent increases in both measures without noticeable increases in muscle size would be ideally suited to most women. Changes in strength and endurance resulting from eight weeks …

The Role Of Fas And Fas Ligand In Apoptosis During Regression Of The Corpus Luteum, Sharon Roughton

Theses : Honours

Apoptosis, a form of physiological cell death, has been found to occur during regression of the corpus luteum (Juengel etal, 1993; Dharmarajan etal, 1994). The pathways involved in this process, however, have yet to be specified. One possible mediator of corpus luteum regression is the Fas (or AP0-1 or CD95) receptor, a transmembrane protein which induces apoptosis in the cell when ligated. In order to further confirm this hypolhesis, the present study establishes and quantitates the presence and regulation of Fas receptor and Fas ligand (Fasl) in the rat corpus luteum during pregnancy and post-partum. The animals used were sexually …

Have A Safe Trip: An Investigation Of Rituals And Sanctions Surrounding Lsd Use, David Wellbourne-Wood

Theses : Honours

There is little recent literature which identifies social controls operating among illicit drug users in Perth, Western Australia. This hinders understanding of the local illicit drug scene and makes the formulation of appropriate harm reduction strategies difficult. This study is a qualitative investigation of rituals and social sanctions which surround the use of Lysergic Acid Diethylamide (LSD). The research describes these rituals and sanctions, and examines their various functions for eight experienced users. The research adopted elements of a phenomenological approach, using in-depth semi-structured interviews to elicit a description of users' subjective experiences with LSD, and Colaizzi's (1978) phenomenological analysis …

The Effects Of 50 Beat Per Minute Music To Decrease Anxiety And Lower Heart Rates In A Select Group Of College Students, Laura E. Burnell

Theses

The purpose of this study was to assess the affect of experimenter chosen 50 beat per minute music composed especially for stress and anxiety reduction on a select group of college students, and to examine its usefulness in promoting relaxation. The rationale for the study was based on research done in the area of using music to promote relaxation, and on the composer's claims that this music has been effective on a variety of populations for such purposes. Thirty subjects comprised of 17 males and 13 females ranging in age from 18 to 25 years participated in the study. This …

The P System: A Scheme For Organizing Pavlovian Procedures, Jose E. Burgos, Rick A. Bevins

Department of Psychology: Faculty Publications

The present paper introduces the P system as a scheme for organizing Pavlovian procedures in an orderly and comprehensive manner. The system is defined by three temporal variables and three restrictions on their possible values. It can be used to define all standard temporal variables—namely, stimulus duration, interstimulus interval, trace interval, and intertrial interval—as well as variables C and T of scalar expectancy theory. The system also permits the definition of new independent variables through combinations of the basic temporal parameters. We exemplify this possibility by defining two ratios of temporal intervals. These ratios lead to a space where traditional …

Trade And Health: The Global Spread Of Diseases And International Trade, David P. Fidler

Articles by Maurer Faculty

No abstract provided.

Controlling Infectious Diseases, David P. Fidler, William Lane Porter

Articles by Maurer Faculty

No abstract provided.

Parasite Biodiversity And Emerging Pathogens: A Role For Systematics In Limiting Impacts On Genetic Resources, Eric P. Hoberg

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Emergence of pathogenic organisms continues as a threat to overall biodiversity and genetic resources. Macroparasites including helminths constitute a potential threat to economically important resources in agriculture and conservation biology. Limitation of this threat can be achieved through survey and inventory for biodiversity and the application of systematics to understand the host range , biogeography and history of faunas. Systematics constitutes the foundation for recognition of endemic and introduced elements of faunas and the basis for predicting the behavior of pathogens introduced to new ecological settings or host groups. The basis for emergence of pathogens has both a deep historical …

Lactose Intolerance In Persistent Diarrhoea During Childhood: The Role Of A Traditional Rice-Lentil (Khitchri) And Yogurt Diet In Nutritional Management, Z A. Bhutta, S Q. Nizami, Z Isani

Department of Paediatrics and Child Health

Lactose intolerance is frequently encountered in children with persistent diarrhoea (PD). Selection of an appropriate milk-based formulation is a major management problem in the developing world. In a consecutive series of studies, we evaluated the role of feeding a traditional rice-lentil (khitchri) diet alone (KY) or in combination with either soy formula (KY-Soy) a dilute buffalo milk (KY-B), in children (age 6 months-3 years) with PD. Serial observations of stool output, caloric intake and weight gain of these children over a 14 day period indicated satisfactory tolerance of the KY diet with adequate weight gain. The weight gain and stool …

Dedicatory Essay: Honoring Ian Mccoll Kennedy, Lawrence O. Gostin

Georgetown Law Faculty Publications and Other Works

Ian Kennedy is perhaps the best known and most important figure in health law and ethics in the United Kingdom, and probably one of the most significant in Europe and North America. How did his life and career evolve to the point where he would wield such influence? This essay examines the leadership, erudition, and passion Ian Kennedy has brought to the field of health law and ethics. It is perhaps not an overstatement to suggest that Professor Kennedy virtually invented the field in the United Kingdom. He did so through his scholarship, public advocacy, and influence in shaping institutions, …

Demonstrating The Need For Health Educators On Short-Term Medical Missions: An Analysis Of Intestinal Parasitic Infections In A Haitian Clinic Population, Janel Jo Brakke

Dissertations and Theses @ UNI

The purpose of this study was to demonstrate the need for health educators on short-term medical missions to developing countries. Specifically, the study was designed to analyze age-specific and gender-specific rates of intestinal parasitic infections in a rural Haitian, mountain clinic population. An extensive review of related literature indicated that 80% of the world's population lives in developing nations, primarily in poverty. Despite the tremendous efforts made by governments and international organizations, the basic health needs of developing nations are not being met (Djukanovic & Mach, 1975; King, 1966; Werner, Thuman, & Maxwell, 1996). Problems of contaminated water, improper sewage …

Differential Endometrial Responses Of Primates Vs Rodents: Screening For Antiproliferative Effects Of Antiprogestins, David Williams Burleigh

Theses and Dissertations in Biomedical Sciences

The antiprogestin, mifepristone, has previously been shown to noncompetitively inhibit estrogen-induced endometrial proliferation in nonhuman primates (van Uem et al., 1989; Wolf et al., 1989b; Neulen et al., 1990; Neulen et al., 1996). For both economical and ethical reasons, we are encouraged to identify comparative laboratory rodent models which can substitute the need to use primate models. In the following study, we compared capabilities of the rat uterine weight bioassay versus a primate uterine bioassay, to identify the noncompetitive antiestrogenic/antiproliferative effects of mifepristone.

Long-term ovariectomized monkeys were exposed to exogenous 17β-estradiol (E2) and mifepristone in doses and regimes already demonstrated …

Arterial Wall Hypertrophy And Pdgf-A Expression In One-Kidney, One-Clip Hypertension And Angiotensin Ii Infusion Are Mediated By Elevated Arterial Pressure, Sheri Blair Parker

Theses and Dissertations in Biomedical Sciences

These studies were designed to characterize the relative roles of angiotensin II (ANG II) and pressure in the structural alterations that occur in experimental hypertension. Two separate studies were performed in order to differentiate these two mechanisms. First, male Wistar rats were subjected to one-kidney, one-clip (1K1C) hypertension or sham operation. Losartan, an AT1 receptor antagonist, was administered chronically to half of each surgical group beginning one day before the operation and continued until the end of the study. In a second experiment, rats were implanted with osmopumps delivering either ANG II or saline. To maintain pressure in the normotensive …

What's Happening: December 26, 1996, Maine Medical Center

What's Happening

No abstract provided.

Method For Obtaining Antifungal And Herbicidal Compounds That Target The First Committed Step In Shingolipid Long-Chain Base Biosynthesis, Robert C. Dickson, Robert L. Lester

Molecular and Cellular Biochemistry Faculty Patents

The invention provides the LCB1 and LCB2 genes of the yeast Saccharomyces cerevisiae that encode subunits of the enzyme serine palmitoyltransferase (SPT), the first enzyme leading to synthesis of the long-base component of the sphingolipids. The present specification describes the isolation of the LCB1 and LCB2 genes. The invention further relates to methods of using these genes to either inhibit SPT activity or to inhibit synthesis of the enzyme. Furthermore, the invention relates to methods for constructing strains of S. cerevisiae or other organisms that can be used to select and to test for compounds that either inhibit SPT activity …

A Comparison Of Olfactory Organ Development And Feeding Behavior In Larval Fathead Minnows, Pimephales Promelas Rafinesque, Robert Molloy

Masters Theses & Specialist Projects

The early recruitment and use of the chemoreceptive senses, olfaction and gustation, are important for early behavior development in fathead minnows and the ability of larvae to survive after hatching. Chemoreception is used in the location of food, avoidance of predators, and for intraspecific communication. Furthermore, some studies have shown the olfactory system to be adversely impacted by environmental contaminants and low pH. Since the fathead minnow is a commercially raised baitfish in the aquaculture industry, and serves as a standard test organism for bioassays and reaction studies of aquatic contamination by the United States Environmental Protection Agency, an understanding …

Prematriculation Immunization Policies: A Survey Of Kentucky Colleges And Universities, Deborah Foushee

Masters Theses & Specialist Projects

Immunizations for vaccine preventable diseases are ordinarily completed by young adulthood, and the school system is typically the institution required to determine compliance with state immunization requirements prior to enrollment. In recent years, outbreaks of measles on college campuses across the United States have led to the implementation of immunization requirements. Kentucky fouryear postsecondary institutions are not required by state law to request proof of immunization. The purpose of this study was to assess prematriculation immunization policies of Kentucky four-year colleges and universities. Participants completed a survey which appraised the existence of a university prematriculation policy, the diseases covered by …

Relational And Liberal Feminism: The Ethic Of Care, Fetal Personhood And Autonomy, Joyce E. Mcconnell

West Virginia Law Review

No abstract provided.

Addressing Spirituality In Occupational Therapy Treatment, Barbara R. Howe

Masters Theses

Literature review identified confusion in the definitions of spirituality with religion. However, there have been attempts to separate the two definitions by professionals who consider holism an important concept of clinical practice. This · study was designed to identify occupational therapists' definitions of spirituality in clinical practice. Also under investigation was the therapist's assessment and use of spirituality for treatment purposes.

A survey was sent to a random sample of occupational therapists in order to gather data about their spiritual activities, their personal definitions of spirituality and their use of spirituality in evaluation and treatment of clients.

Occupational therapists who …

Basement Membrane And Repair Of Injury To Peripheral Nerve: Defining A Potential Role For Macrophages, Matrix Metalloproteinases, And Tissue Inhibitor Of Metalloproteinases-1, Monique La Fleur, Johnnie L. Underwood, Daniel A. Rappolee, Zena Werb

Department of Obstetrics and Gynecology Research Publications

Injury to a peripheral nerve is followed by a remodeling process consisting of axonal degenera- tion and regeneration. It is not known how Schwann cell–derived basement membrane is pre- served after injury or what role matrix metalloproteinases (MMPs) and their inhibitors play in axonal degeneration and regeneration. We showed that the MMPs gelatinase B (MMP-9), stromelysin-1 (MMP-3), and the tissue inhibitor of MMPs (TIMP)-1 were induced in crush and distal segments of mouse sciatic nerve after injury. TIMP-1 inhibitor activity was present in excess of proteinase activity in extracts of injured nerve. TIMP-1 protected basement mem- brane type IV collagen …

Full Issue, The Mcnair Team

McNair Scholars Research Journal

No abstract provided.

Jefferson Alumni Bulletin – Volume Xlvi, Number 1, December 1996

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XLVI, Number 1, December 1996

Rational Drug Design, Page 4

Technology Transfer, Page 7

Clinical Trials, Page 9

World-Class Athletes and Drugs, Page 12

The Makings of the Complete Physician, Page 14

Major Alliance Links Jefferson with Mercy Health, Page 17

“Gene Repair” Corrects Mutation Leading to Disease, Page 19

Genetic Discoveries Lead to New Lung Cancer Tests, Page 20

Alumni Can Participate in JeffHOPE, Page 24

Student AMA Organizes Bone Marrow Drive, Page 25

Method And Compositions For Treating Age Related Disorders, John M. Carney, Robert A. Floyd

Pharmacology and Nutritional Sciences Faculty Patents

Compositions containing as the active ingredient a spin-trapping reagent, preferably α-phenyl butyl nitrone (PBN) or spin-trapping derivatives thereof, in a suitable pharmaceutical carrier for administration to a patient are disclosed for treating or preventing symptoms associated with aging or other conditions associated with oxidative tissue damage. Other spin-trapping agents can also be used, such as 5,5-dimethyl pyrroline N-oxide (DMPO) or α-(4-pyridyl 1-oxide)-N-tert-butylnitrone (POBN), and other spin-trapping derivatives thereof. These compositions and methods are useful in the treatment of age-related disorders, pre-surgical and/or pre-anesthetic preparation or administration of chemotherapeutic agents, and in the treatment of disorders or trauma of the brain, …

Helminths Of The Southwestern Toad, Bufo Microscaphus, Woodhouse's Toad, Bufo Woodhousii (Bufonidae), And Their Hybrids From Central Arizona, Stephen R. Goldberg, Charles R. Bursey, Keith B. Malmos, Brian K. Sullivan, Hay Cheam

Great Basin Naturalist

The gastrointestinal tracts, lungs, and urinary bladders from 77 Bufo microscaphus, 61 Bufo woodhousii, and 8 of their hybrids were examined for helminths. One species of trematode (Glypthelmins quieta), 1 species of cestode (Distoichometra bufonis), and 5 species of nematodes (Aplectana incerta, A. itzocanensis, Rhabdias americanus, Physaloptera sp., and Physocephalus sp.) were found. The greatest prevalence (41%) and mean intensity (231.7) were recorded for Aplectana incerta in Bufo woodhousii. It appears hybrids harbor fewer parasites than either parent species.

Nonparaphilic Sexual Addiction, Mark Kahabka

The Linacre Quarterly

No abstract provided.

Cellular Basis Of Decreased Immune Responses To Pneumococcal Vaccines In Aged Mice, Manju Garg, Wei Luo, Alan M. Kaplan, Subbarao Bondada

Microbiology, Immunology, and Molecular Genetics Faculty Publications

Previously, model systems were developed in our laboratory to study murine immune responses to the 23-valent pneumococcal polysaccharide vaccine Pnu-Imune, both in vivo and in vitro (M. Garg and B. Subbarao, Infect. Immun. 60:2329-2336, 1992; M. Garg, A. M. Kaplan, and S. Bondada, J. Immunol. 152: 1589-1596, 1994). Using these systems, we found that aged mice did not respond to the vaccine in vivo or in vitro. Cell separation studies showed that the unresponsiveness of the aged spleen cells to the vaccine was not due to an intrinsic B-cell defect or to T-cell-mediated immunosuppression but resulted from an accessory cell …

Basics Of Research (Part 8): Unique Aspects Of Nursing Research, Cheryl Thompson, Cheryl J. Erler

Journal Articles: College of Nursing

No abstract provided.