Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

Medicine and Health Sciences

Institution
Keyword
Publication Year
Publication
Publication Type
File Type

Articles 57811 - 57840 of 63906

Full-Text Articles in Entire DC Network

Transitional Cell Carcinoma Of The Urinary Bladder In A Dog : A Case Report, Chollada Buranakarl, Phiwipha Kamonrat, Rachod Tantilertcharoen Mar 1998

Transitional Cell Carcinoma Of The Urinary Bladder In A Dog : A Case Report, Chollada Buranakarl, Phiwipha Kamonrat, Rachod Tantilertcharoen

The Thai Journal of Veterinary Medicine

A urinary bladder mass was diagnosed in a 14-year-old uncastrated male mixed breed dog presented to the Small Animal Teaching Hospital, Faculty of Veterinary Science, Chulalongkorn University. The dog had periodic hematuria which had been present for eight months without any abnormalities on complete blood count and all other blood chemistry. Radiographic examination revealed a prostate gland enlargement with evidence of irregular thickening of the urinary bladder mucosa without any cystic calculi. Antibiotics and hemostatic drugs were given and hematuria ceased periodically. With a history of concurrent hematuria and an elevation of both blood urea nitrogen (109 mg%) and creatinine …


Development, Reproductive Capacity And Survival Of Amblyomma Variegatum And Boophilus Decoloratus In Relation To Host Resistance And Climatic Factors Under Field Conditions, G. Solomon, G. P. Kaaya Feb 1998

Development, Reproductive Capacity And Survival Of Amblyomma Variegatum And Boophilus Decoloratus In Relation To Host Resistance And Climatic Factors Under Field Conditions, G. Solomon, G. P. Kaaya

All Peer-Reviewed Publications

To determine the developmental periods, fecundity and survival of Amblyomma variegatum and Boophilus decoloratus and the effect of host resistance, a study was carried out in the field at Abemossa ranch in Ethiopia using three breeds of cattle: Arssi, Baran and Baran X Friesian crossbreed. The investigation took place between October 1991 and September 1992. The developmental periods of both tick species were recorded. The hatching periods of larvae, engorgement, larvo-nymphal and nympho-adult moulting periods during various climatic seasons in shaded and dry areas were also recorded. While the engorgement periods recorded on the animal were relatively constant for each …


Fornix Lesions Can Facilitate Acquisition Of The Transverse Patterning Task: A Challenge For "Configural" Theories Of Hippocampal Function., T J Bussey, E Clea Warburton, J P Aggleton, J L Muir Feb 1998

Fornix Lesions Can Facilitate Acquisition Of The Transverse Patterning Task: A Challenge For "Configural" Theories Of Hippocampal Function., T J Bussey, E Clea Warburton, J P Aggleton, J L Muir

Brain and Mind Institute Researchers' Publications

Configural theories of hippocampal function predict that hippocampal dysfunction should impair acquisition of the transverse patterning task, which involves the concurrent solution of three discrimination problems: A+ versus B-; B+ versus C-; and C+ versus A-. The present study tested this prediction in rats using computer-graphic stimuli presented on a touchscreen. Experiment 1 assessed the effects of fornix lesions when the three problems were introduced sequentially (phase 1: A+ vs B-; phase 2: A+ vs B-, B+ vs C-; phase 3: A+ vs B-, B+ vs C-, C+ vs A-). Fornix lesions significantly facilitated acquisition of the complete transverse patterning …


Gynandropsis Gynandra Essential Oil And Its Constituents As Tick (Rhipicephalus Appendiculatus) Repellents, W. Lwande, A. J. Ndakala, A. Hassanali, L. Moreka, E. Nyandat, M. Ndungu, H. Amiani, P. M. Gitu, M. M. Malonza, D. K. Punyua Feb 1998

Gynandropsis Gynandra Essential Oil And Its Constituents As Tick (Rhipicephalus Appendiculatus) Repellents, W. Lwande, A. J. Ndakala, A. Hassanali, L. Moreka, E. Nyandat, M. Ndungu, H. Amiani, P. M. Gitu, M. M. Malonza, D. K. Punyua

All Peer-Reviewed Publications

The repellency of the essential oil of the previously reported anti- tick pasture shrub Gynandropsis gynandra and identified constituents of the oil were evaluated against the livestock tick, Rhipicephalus appendiculatus. In a tick-climbing repellency bioassay, the oil of G. gynandra exhibited a repellency effect which at the highest treatment levels was higher than that of the commercial arthropod repellent N,N-diethyltoluamide. Twenty eight compounds were identified in the G. gynandra oil by GC, GC-MS and coinjection with authentic samples. Carvacrol was found to occur in largest quantity (29.2%), followed by trans-phytol (24.0%), linalool (13.3%), trans-2- methylcyclopentanol (7.2%) and β-caryophyllene (4.4%). m-Cymene, …


Bordetella Holmesii-Like Organisms Associated With Septicemia, Endocarditis, And Respiratory Failure, Perry J. Severance, Yi-Wei Tang, Marlene K. Hopkins, Christopher P. Kolbert, Paul A. Hartley, David H. Persing Feb 1998

Bordetella Holmesii-Like Organisms Associated With Septicemia, Endocarditis, And Respiratory Failure, Perry J. Severance, Yi-Wei Tang, Marlene K. Hopkins, Christopher P. Kolbert, Paul A. Hartley, David H. Persing

Articles

We recovered an unusual bacterial strain from blood or sputum of three patients with septicemia, endocarditis, and/or respiratory failure. The three isolates were thin, curved, gram-negative, light brown, pigment-producing bacilli with variable catalase activity. They were asaccharolytic, oxidasenegative, nonmotile, and fastidious. Identification was not possible on the basis of these characteristics alone or in combination with cellular fatty acid profiles. Nucleic acid amplification and sequence analysis of the 16S rRNA gene revealed that all three isolates were identical and most closely related to the emerging pathogen Bordetella holmesii, diverging from the published sequence at three nucleotide positions (99.8% similarity). …


Dentalgram - Vol. 12, No. 02, Loma Linda University School Of Dentistry Feb 1998

Dentalgram - Vol. 12, No. 02, Loma Linda University School Of Dentistry

Dentalgram

In this issue

  • Alumni-Student Convention
  • Frenectomies abound
  • On-site authorization
  • Weingart Foundation grant
  • Connected concert
  • Department news
  • Employee of the Quarter
  • Fall '97 Dean's List


[Book Review Of] Theologies Of The Body: Human And Christian, By Benedict Ashley, O.P., Patrick Lee Feb 1998

[Book Review Of] Theologies Of The Body: Human And Christian, By Benedict Ashley, O.P., Patrick Lee

The Linacre Quarterly

No abstract provided.


Mechanism Of Triazolo-Benzodiazepine And Benzodiazepine Action In Anxiety And Depression: Behavioral Studies With Concomitant In Vivo Ca1 Hippocampal Norepinephrine And Serotonin Release Detection In The Behaving Animal, Patricia A. Broderick, Omotola Hope, Pierrot Jeannot Feb 1998

Mechanism Of Triazolo-Benzodiazepine And Benzodiazepine Action In Anxiety And Depression: Behavioral Studies With Concomitant In Vivo Ca1 Hippocampal Norepinephrine And Serotonin Release Detection In The Behaving Animal, Patricia A. Broderick, Omotola Hope, Pierrot Jeannot

Publications and Research

1. Real time, in vivo microvoltammetric studies were performed, using miniature carbon-based sensors, to concurrently detect norepinephrine (NE) release and serotonin (5-HT) release, in 2 separate electrochemical signals, within CA1 region of hippocampus in the freely moving and behaving, male, Sprague Dawley laboratory rat.

2. Concurrently, four parameters of open-field Behavior I.E. Ambulations, Rearing, Fine Movements and Central Ambulatory behavior (a measure of anxiety reduction behavior), were assayed by infrared photobeam detection.

3. Time course studies showed that the mechanism of action of the triazolobenzodiazepine (TBZD), adinazolam, (Deracyn®) is dramatically different from that of the classical benzodiazepine (BZD), diazepam …


Dna Methylation And Carcinogenesis In Digestive, Javed Yakoob, Fan Xue-Gong, Hu Guo-Ling, Zhang Zheng Feb 1998

Dna Methylation And Carcinogenesis In Digestive, Javed Yakoob, Fan Xue-Gong, Hu Guo-Ling, Zhang Zheng

Section of Gastroenterology

No abstract provided.


Investigation Of The Roles Of Toxin-Coregulated Pili And Mannose-Sensitive Hemagglutinin Pili In The Pathogenesis Of Vibrio Cholerae O139 Infection, Carol O. Tacket, Ronald K. Taylor, Genevieve Losonsky, Yu Lim Feb 1998

Investigation Of The Roles Of Toxin-Coregulated Pili And Mannose-Sensitive Hemagglutinin Pili In The Pathogenesis Of Vibrio Cholerae O139 Infection, Carol O. Tacket, Ronald K. Taylor, Genevieve Losonsky, Yu Lim

Dartmouth Scholarship

In this study, adult volunteers were fed tcpA and mshA deletion mutants of V. cholerae O139 strain CVD 112 to determine the role of toxin-coregulated pili (TCP) and mannose-sensitive hemagglutinin (MSHA) in intestinal colonization. Eight of 10 volunteers who received CVD 112 or CVD 112 ΔmshA shed the vaccine strains in their stools; the geometric mean peak excretion for both groups was 1.4 × 105 CFU/g of stool. In contrast, only one of nine recipients of CVD 112 ΔtcpA shed vibrios in his stool (P < 0.01); during the first 24 h after inoculation, 3 × 102 CFU/g was recovered from this volunteer. All recipients of CVD …


Proactive Technique For Workplace Chemical Exposure, James A. Duru Jan 1998

Proactive Technique For Workplace Chemical Exposure, James A. Duru

Theses

The rapid increase in the number and quantities of chemicals released into the environment has been accompanied by a lack of adequate pre-released testing for advance health outcomes. Chemicals which serve as feed stock to millions of industries all around the world to produce and process food, cosmetics, equipment, and energy to propel industries, automobiles, home heating and electricity have serious adverse health consequences. They are hazardous. These substances can explode, ignite, react and corrode. Adapting the definition of the international program on chemical safety, a "hazard" is a source of danger. This thesis proposes some proactive prevention techniques useful …


Randomly Amplified Polymorphic Dna Analysis (Rapd) Of Artemisia Subgenus Tridentatae Species And Hybrids, E. Durant Mcarthur, Joann Mudge, Renée Van Buren, W. Ralph Andersen, Stewart C. Sanderson, David G. Babbel Jan 1998

Randomly Amplified Polymorphic Dna Analysis (Rapd) Of Artemisia Subgenus Tridentatae Species And Hybrids, E. Durant Mcarthur, Joann Mudge, Renée Van Buren, W. Ralph Andersen, Stewart C. Sanderson, David G. Babbel

Great Basin Naturalist

Species of Artemisia (subgenus Tridentatae) dominate much of western North America. The genetic variation that allows this broad ecological adaptation is facilitated by hybridization and polyploidization. Three separate studies were performed in this group using randomly amplified polymorphic DNA (RAPD). Fifty-seven 10-mer primers generated nearly 400 markers from genomic DNA obtained from leaf tissue. These studies were (1) a measure of the variability of plants within and between populations and between subspecies using 5 A. tridentata ssp. wyomingensis populations, 2 A. cana ssp. cana populations, and 1 A. cana ssp. viscidula population; (2) an examination of the hypothesis that …


Differences In Lean And Obese Skeletal Muscle Myoblasts Of Adult And Post-Natal La/N (Faf) Rats: A Confocal Description Of The Skeletal Muscle Myoblast, J. Adam Noah Jan 1998

Differences In Lean And Obese Skeletal Muscle Myoblasts Of Adult And Post-Natal La/N (Faf) Rats: A Confocal Description Of The Skeletal Muscle Myoblast, J. Adam Noah

Theses, Dissertations and Capstones

Mutant strains of obese rats are currently being studied to reveal the mechanisms of increased lipid synthesis and decreased lipid oxidation in these rats. It was originally thought that much of the fat production that leads to obesity is the result of metabolic processes in the liver and adipose tissue. Studies by Kahle et al.3 showed that the liver and adipose tissue account for only 22% and 7% respectively, of total fatty acid synthesis. It was also shown that 21 % of total de novo fatty acid was localized in the postural skeletal muscle.

The dry weight of the …


Land Use Patterns In Relation To Lake Water Quality In The Great Pond Watershed, Problems In Environmental Science Course (Biology 493), Colby College, Colby Environmental Assessment Team, Colby College Jan 1998

Land Use Patterns In Relation To Lake Water Quality In The Great Pond Watershed, Problems In Environmental Science Course (Biology 493), Colby College, Colby Environmental Assessment Team, Colby College

Colby College Watershed Study: Great Pond (2012, 2010, 1998)

Lakes are natural resources, which have many effects on the land surrounding them, They support adjacent communities by providing water and regulating temperatures, helping to define the surrounding ecosystem, and serving as sources of drinking water as well as recreation. The prolonged presence of human activity in a watershed can disturb the physical and chemical cycles of the lake and its surrounding ecosystems (Henderson-Sellers and Markland 1987). Over time, lakes undergo a process called eutrophication, a natural aging process during which the nutrient levels increase and dissolved oxygen levels decrease (Smith and Smith 1998). As the lake ages or becomes …


Atovaquone Compared With Dapsone For The Prevention Of Pneumocystis Carinii Pneumonia In Patients With Hiv Infection Who Cannot Tolerate Trimethoprim, Sulfonamides, Or Both, Wafaa M. El-Sadr , M.D., M.P.H., Robert L. Murphy , M.D., Teresa Mccabe Yurik , M.S., Roberta Luskin-Hawk , M.D., Tony W. Cheung , M.D., Henry H. Balfour , Jr., M.D., Robert Eng , M.D., Thomas M. Hooton , M.D., Thomas M. Kerkering , M.D., Malte Schutz , M.D., Charles Van Der Horst , M.D., Richard Hafner , M.D. Jan 1998

Atovaquone Compared With Dapsone For The Prevention Of Pneumocystis Carinii Pneumonia In Patients With Hiv Infection Who Cannot Tolerate Trimethoprim, Sulfonamides, Or Both, Wafaa M. El-Sadr , M.D., M.P.H., Robert L. Murphy , M.D., Teresa Mccabe Yurik , M.S., Roberta Luskin-Hawk , M.D., Tony W. Cheung , M.D., Henry H. Balfour , Jr., M.D., Robert Eng , M.D., Thomas M. Hooton , M.D., Thomas M. Kerkering , M.D., Malte Schutz , M.D., Charles Van Der Horst , M.D., Richard Hafner , M.D.

Internal Medicine Publications

BACKGROUND

Although trimethoprim–sulfamethoxazole is the drug of choice for the prevention of Pneumocystis carinii pneumonia, many patients cannot tolerate it and must switch to an alternative agent.

METHODS

We conducted a multicenter, open-label, randomized trial comparing daily atovaquone (1500-mg suspension) with daily dapsone (100 mg) for the prevention of P. carinii pneumonia among patients infected with the human immunodeficiency virus who could not tolerate trimethoprim–sulfamethoxazole. The median follow-up period was 27 months.

RESULTS

Of 1057 patients enrolled, 298 had a history of P. carinii pneumonia.P. cariniipneumonia developed in 122 of 536 patients assigned to atovaquone (15.7 cases per …


Progestin Stimulation Of The Protooncogene C-̲M̲Y̲C In T47d Human Breast Cancer Cells, Kristy Ann Blankenship Jan 1998

Progestin Stimulation Of The Protooncogene C-̲M̲Y̲C In T47d Human Breast Cancer Cells, Kristy Ann Blankenship

Theses, Dissertations and Capstones

Moore and co-workers have previously demonstrated that progestins stimulate the growth of T47D human breast cancer cells. We now investigate the possibility that progestins might transactivate the protooncogcne c-myc as part of the mechanism for growth stimulation. Treatment of T47D cells with the synthetic progestin R5020 results in a rapid, dose-dependent increase in c-myc mRNA. This stimulation is evident as early as 5 minutes, increases up to 4-fold at 1 hour, and then returns toward basal levels. The optimal concentration of R5020 for induction of c-myc gene expression is 10 nM, which is within the physiologically relevant range of hormone …


Ada News Daily - 1998 Day 4, American Dental Association, Publishing Division Jan 1998

Ada News Daily - 1998 Day 4, American Dental Association, Publishing Division

ADA News

The ADA News Daily (also called the ADA News Convention Daily) is a special edition of the ADA News published each day during American Dental Association Annual Sessions.


Ada News Daily - 1998 Day 2, American Dental Association, Publishing Division Jan 1998

Ada News Daily - 1998 Day 2, American Dental Association, Publishing Division

ADA News

The ADA News Daily (also called the ADA News Convention Daily) is a special edition of the ADA News published each day during American Dental Association Annual Sessions.


Patent: Male Contraceptive Implant, Alfred J. Moo-Young, Saleh I. Saleh Jan 1998

Patent: Male Contraceptive Implant, Alfred J. Moo-Young, Saleh I. Saleh

Formulation/Product Development

The present invention relates to implantable male contraceptive devices. An ethylene vinyl acetate copolymer based implant is described for delivery of an androgen and a system including an ethylene vinyl acetate copolymer based implant as well as a second implantare described for the administration of both androgen and a sterilitant. These implants may be used to provide contraception for men, as well as, for hormone therapy, treatment of enlarged prostate and other aliments.


Glycoprotein Iib/Iiia Inhibitors In Acute Coronarysyndromes: A New Paradigm In Cardiology, Mehmet Ağirbaşli, David M. Kerins Jan 1998

Glycoprotein Iib/Iiia Inhibitors In Acute Coronarysyndromes: A New Paradigm In Cardiology, Mehmet Ağirbaşli, David M. Kerins

Turkish Journal of Medical Sciences

No abstract provided.


Characteristics And Treatment Of Conduct Disorders, Vicky Jo Kukral Jan 1998

Characteristics And Treatment Of Conduct Disorders, Vicky Jo Kukral

Graduate Research Papers

Conduct Disorder is the most diagnosed condition in both outpatient and inpatient mental health facilities for children in the United States. Behavior problems such as aggression, destruction of property, theft and violation of basic rules are concerns for parents, teachers, peers and other adults. In an effort to help increase the reader's understanding of the Conduct Disorder population and their treatment, the author of this paper will describe and characteristics of this population. The author will also address specific mental health concerns as found in a review of the literature, and the status of mental health treatment.


Rehabilitation Of Obesity, Patricia Ann Thomas Jan 1998

Rehabilitation Of Obesity, Patricia Ann Thomas

Theses Digitization Project

This project investigates the many influences throughout the life span that interact to cause obesity. Heredity factors, overfeeding in infancy and childhood, repeated dieting, inactivity, lifestyle and psychosocial conditions all contribute to the incidence of obesity.


Psychology's Use Of Animals: Current Practices And Attitudes, Kenneth J. Shapiro Jan 1998

Psychology's Use Of Animals: Current Practices And Attitudes, Kenneth J. Shapiro

Experimentation Collection

In this chapter, I present a psychology primer for the uninitiated, with special emphasis on psychology's uses of animals. After sketching the scope of the field generally, I review available data on present numbers and species of animals used in psychological research, level of suffering induced and current trends. I also provide several concrete examples of psychological research involving animals. Finally, the chapter concludes with a presentation of attitudes of psychologists toward animals and these practices.


Human Granulocytic Ehrlichiosis In Europe: Clinical And Laboratory Findings For Four Patients From Slovenia, Stanka Lotric-Furlan, Miroslav Petrovec, Tatjana Avsic Zupanc, William L. Nicholson, John W. Sumner, James E. Childs, Franc Strle Jan 1998

Human Granulocytic Ehrlichiosis In Europe: Clinical And Laboratory Findings For Four Patients From Slovenia, Stanka Lotric-Furlan, Miroslav Petrovec, Tatjana Avsic Zupanc, William L. Nicholson, John W. Sumner, James E. Childs, Franc Strle

Zoonotics and Wildlife Disease: Publications

Febrile illnesses following a tick bite in patients from Slovenia were evaluated for an ehrlichial etiology. A case of acute human granulocytic ehrlichiosis (HGE) was confirmed by seroconversion to the HGE agent or molecular identification of ehrlichial organisms. Acute infection with the HGE agent was confirmed in four patients. None of the patients had detectable antibodies to the HGE agent at their first visit, but polymerase chain reaction analysis was positive for three patients. All four patients subsequently seroconverted to the HGE agent as shown by high titers of antibody. Clinical features and laboratory findings were similar to those in …


Ecologic Studies Of Rodent Reservoirs: Their Relevance For Human Health, James N. Mills, James E. Childs Jan 1998

Ecologic Studies Of Rodent Reservoirs: Their Relevance For Human Health, James N. Mills, James E. Childs

Zoonotics and Wildlife Disease: Publications

Within the past few years, the number of “new” human diseases associated with small-mammal reservoirs has increased dramatically, stimulating renewed interest in reservoir ecology research. A consistent, integrative approach to such research allows direct comparisons between studies, contributes to the efficient use of resources and data, and increases investigator safety. We outline steps directed toward understanding vertebrate host ecology as it relates to human disease and illustrate the relevance of each step by using examples from studies of hosts associated with rodent-borne hemorrhagic fever viruses.


Serologic Evidence Of Infection With Ehrlichia Spp. In Wild Rodents (Muridae: Sigmodontinae) In The United States, William L. Nicholson, Susie Muir, John W. Sumner, James E. Childs Jan 1998

Serologic Evidence Of Infection With Ehrlichia Spp. In Wild Rodents (Muridae: Sigmodontinae) In The United States, William L. Nicholson, Susie Muir, John W. Sumner, James E. Childs

Zoonotics and Wildlife Disease: Publications

Rodent (Muridae: Sigmodontinae) blood and sera collected from 14 states were tested for seroreactivity to a cultured isolate of the human granulocytic ehrlichiosis (HGE) agent by using an indirect immunofluorescence assay. Of the 1,240 samples tested, 136 (11%) were found to be reactive at titers of ≥32. Rodents with HGE agent-specific antibodies were found in New York (23% of 491 samples; geometric mean endpoint titer GMT = 441), Connecticut (11% of 100 samples; GMT = 481), California (9% of 32 samples; GMT = 323), Colorado (2% of 212 samples; GMT = 256), Florida (7% of 27 samples; GMT = 362), …


Dietary Habits Of The Common Rodents In An Agrecosystem In Argentina, Barbara A. Ellis, James N. Mills, Gregory E. Glass, Kelly T. Mckee Jr, Delia A. Enria, James E. Childs Jan 1998

Dietary Habits Of The Common Rodents In An Agrecosystem In Argentina, Barbara A. Ellis, James N. Mills, Gregory E. Glass, Kelly T. Mckee Jr, Delia A. Enria, James E. Childs

Zoonotics and Wildlife Disease: Publications

Dietary habits of five common rodents in agroecosystems on the central Argentine Pampa were studied for 15 months using microhistological analysis of stomach contents. All five rodent species were omnivorous, but proportions of major dietary items (arthropods, dicot leaves and seeds, monocot leaves and seeds) varied among species and seasons. Akodon azarae largely was entomophagous; arthropods formed 41-62% of the diet in all seasons. The other four species (Calomys musculinus, Calomys laucha, Bolomys obscurus, and Oligoryzomys flavescens) consumed most diet items throughout the year, but relative proportions varied among seasons. Leaves formed a relatively minor proportion of the …


Monoclonal Antibody F89/160.1.5 Defines A Conserved Epitope On The Ruminant Prion Protein, Katherine I. O'Rourke, Timothy V. Baszler, Janice M. Miller, Terry R. Spraker, Ingrid Sadler-Riggleman, Donald P. Knowles Jan 1998

Monoclonal Antibody F89/160.1.5 Defines A Conserved Epitope On The Ruminant Prion Protein, Katherine I. O'Rourke, Timothy V. Baszler, Janice M. Miller, Terry R. Spraker, Ingrid Sadler-Riggleman, Donald P. Knowles

Zoonotics and Wildlife Disease: Publications

The transmissible spongiform encephalopathies are a heterogeneous group of fatal neurodegenerative disorders occurring in humans, mink, cats, and ruminant herbivores. The occurrence of novel transmissible spongiform encephalopathies in cattle in the United Kingdom and Europe and in mule deer and elk in parts of the United States has emphasized the need for reliable diagnostic tests with standardized reagents. Postmortem diagnosis is performed by histologic examination of brain sections from affected animals. The histopathological criteria for transmissible spongiform encephalopathies include gliosis, astrocytosis, neuronal degeneration, and spongiform change. These lesions vary in intensity and anatomic location depending on the host species and …


Preclinical Detection Of PrpSc In Nictitating Membrane Lymphoid Tissue Of Sheep, Katherine I. O'Rourke, T. V. Baszler, S. M. Parish, D. P. Knowles Jan 1998

Preclinical Detection Of PrpSc In Nictitating Membrane Lymphoid Tissue Of Sheep, Katherine I. O'Rourke, T. V. Baszler, S. M. Parish, D. P. Knowles

Zoonotics and Wildlife Disease: Publications

SHEEP scrapie is the prototype of a heterogeneous group of transmissible spongiform encephalopathies (TSES) which occur in humans, cattle, cats, mink and cervids. TSEs are characterised by the deposition of prion proteins (Prp-Scrapie or PrpSc) in the central nervous system of affected individuals (Prusiner 1982). PrPSc and infectivity have also been detected in the lymphoreticular system of sheep well before symptoms occur (Hadlow and others 1982, Race and others 1992). Detection of PrpSc in lymphoid tissue, such as tonsils or peripheral lymph nodes, has been proposed as a preclinical diagnostic test for scrapie (Ikegami and others …


Santa Clara Magazine, Volume 39 Number 4, Winter 1998, Santa Clara University Jan 1998

Santa Clara Magazine, Volume 39 Number 4, Winter 1998, Santa Clara University

Santa Clara Magazine

10 - INSIDE OUT Francisco Jimenez, chairman of the University's Modern Languages and Literatures Department, recalls his grade-school days and immigrant family.

14 - FROM HALLOWED TO HIP Connie Hinckley, East Bay writer, examines the media's many-faceted portrayals of the priesthood, especially the controversial Father Ray of Nothing Sacred.

20 - SANTA CLARA'S ADOBE LEGACY Susan Vogel, San Francisco author and publisher, traces the history of the Adobe Lodge and describes its many roles in the life of the University.

26 - UNCOVERING THE REGION'S RICH PAST As the University clears land for new buildings, SCU archeologists and Native American …