Open Access. Powered by Scholars. Published by Universities.®
- Institution
-
- The Texas Medical Center Library (7913)
- TÜBİTAK (4189)
- Washington University School of Medicine (3161)
- Thomas Jefferson University (3160)
- University of Nebraska - Lincoln (3107)
-
- University of Kentucky (2701)
- Virginia Commonwealth University (1410)
- Chulalongkorn University (1401)
- University of Alabama at Birmingham (1050)
- Aga Khan University (897)
- University of Nebraska Medical Center (886)
- Loma Linda University (877)
- Edith Cowan University (765)
- University of Texas Rio Grande Valley (757)
- Old Dominion University (713)
- Loyola University Chicago (703)
- Marquette University (625)
- City University of New York (CUNY) (623)
- Dartmouth College (621)
- Chapman University (618)
- University of Louisville (613)
- University of South Florida (603)
- Himmelfarb Health Sciences Library, The George Washington University (599)
- Touro College and University System (561)
- University of South Carolina (552)
- Brigham Young University (518)
- University of Arkansas, Fayetteville (516)
- Zucker School of Medicine at Hofstra/Northwell (490)
- Henry Ford Health (479)
- LSU Health New Orleans (467)
- Keyword
-
- Animals (7931)
- Humans (7218)
- Mice (5195)
- Female (2913)
- Male (2768)
-
- ICTS (Institute of Clinical and Translational Sciences) (1652)
- Mice, Inbred C57BL (1096)
- Disease Models, Animal (970)
- Inflammation (948)
- Animal (877)
- Cell Line (823)
- Tumor (815)
- Cell Line, Tumor (810)
- Inbred C57BL (799)
- Adult (769)
- Signal Transduction (758)
- Brain (719)
- Rats (707)
- COVID-19 (693)
- Doctor of Philosophy (PhD) Heersink School of Medicine (691)
- Disease Models (678)
- Obesity (667)
- Mice, Knockout (649)
- Receptors (637)
- Mutation (601)
- Middle Aged (597)
- Cancer (588)
- Apoptosis (570)
- Aging (566)
- Neoplasms (548)
- Publication Year
- Publication
-
- Faculty, Staff and Student Publications (3903)
- Turkish Journal of Veterinary & Animal Sciences (3215)
- Faculty, Staff and Students Publications (2777)
- 2020-Current year OA Pubs (2386)
- Theses and Dissertations (1256)
-
- All ETDs from UAB (1015)
- Turkish Journal of Medical Sciences (974)
- Chulalongkorn University Theses and Dissertations (Chula ETD) (826)
- Electronic Theses and Dissertations (763)
- Loma Linda University Electronic Theses, Dissertations & Projects (629)
- United States Department of Agriculture Wildlife Services: Staff Publications (596)
- Dartmouth Scholarship (585)
- Dissertations and Theses (Open Access) (561)
- Master's Theses (555)
- Open Access Publications (523)
- Journal Articles (499)
- The Thai Journal of Veterinary Medicine (491)
- Dissertations (479)
- Henry Ford Hospital Medical Journal (479)
- School of Medicine Publications (444)
- Nebraska Beef Cattle Reports (441)
- Walden Dissertations and Doctoral Studies (392)
- USF Tampa Graduate Theses and Dissertations (373)
- Publications and Research (361)
- School of Veterinary and Biomedical Sciences: Faculty Publications (357)
- Theses and Dissertations (ETD) (356)
- Pharmacy Faculty Articles and Research (333)
- Research outputs 2022 to 2026 (330)
- Faculty Publications (304)
- Journal of the Department of Agriculture, Western Australia, Series 4 (300)
- Publication Type
Articles 57781 - 57810 of 63910
Full-Text Articles in Entire DC Network
Louisiana State University Medical Center - 1998 - Spring Commencement, Office Of The Registrar, Lsu Health Sciences Center-No
Louisiana State University Medical Center - 1998 - Spring Commencement, Office Of The Registrar, Lsu Health Sciences Center-No
Graduation & Commencement Programs
The program for the 1998 Spring Commencement of LSU Health Sciences Center - New Orleans held May 16, 1998.
Knowledge, Attitudes And Behavior Of African American Undergraduate College Students Concerning Primary Preventative Health, Lionas Mayes
Knowledge, Attitudes And Behavior Of African American Undergraduate College Students Concerning Primary Preventative Health, Lionas Mayes
McCabe Thesis Collection
African Americans' knowledge about primary preventive health and their attitudes toward primary preventive health influence their health behavior. Primary preventive health behavior is also affected by the individuals' definition of health and the significance they ascribe to their health status. Attitudes toward primary preventive health determine whether health assessment is important in preventing disease. African Americans have a myriad of views about health and general well being. The purpose of this study is to determine the relationship between primary preventive health knowledge, primary preventive health attitudes and primary preventive health behavior in African American undergraduate students. A survey will be …
ผลการเรียนของนิสิตทันตแพทย์ เมื่อใช้บทเรียนคอมพิวเตอร์เป็นสื่อประกอบการสอนในวิชาครอบและสะพานฟัน, มรกต ตันติประวรรณ
ผลการเรียนของนิสิตทันตแพทย์ เมื่อใช้บทเรียนคอมพิวเตอร์เป็นสื่อประกอบการสอนในวิชาครอบและสะพานฟัน, มรกต ตันติประวรรณ
Chulalongkorn University Dental Journal
วัตถุประสงค์ เพื่อวัดผลคะแนนทดสอบของนิสิตชั้นปีที่ 4 ภายหลังการเรียนการสอน โดยใช้สื่อประกอบการสอน บทเรียนคอมพิวเตอร์ช่วยสอน เปรียบเทียบกับการใช้แผ่นใสและภาพนิ่ง ในวิชาครอบและสะพานฟัน หัวข้อเรื่อง ฟันปลอมชนิดติดแน่นที่รองรับด้วยรากเทียม วัสดุและวิธีการ กลุ่มที่ 1 นิสิตชั้นปีที่ 4 ภาคการศึกษาต้น ปีการศึกษา 2539 จํานวน 101 คน เข้ารับการเรียน การสอน โดยใช้บทเรียนคอมพิวเตอร์ช่วยสอนเป็นสื่อประกอบการสอน ตามตารางการสอนของวิชาครอบและสะพาน ฟัน ประจําปีการศึกษา 2539 กลุ่มที่ 2 นิสิตชั้นปีที่ 4 ภาคการศึกษาต้น ปีการศึกษา 2540 เข้ารับการเรียนการสอน โดยใช้แผ่นใสและภาพนิ่งเป็นสื่อประกอบการสอน ตามตารางการสอนของวิชาครอบและสะพานฟัน ประจําปีการศึกษา 2540 จํานวน 100 คน นิสิตทั้ง 2 กลุ่ม ทําแบบทดสอบก่อนการเรียนใช้เวลา 10 นาที จากนั้นอาจารย์ผู้สอน บรรยายประกอบสื่อการสอน และตอบข้อซักถามเป็นเวลา 40 นาที นิสิตทําแบบทดสอบหลังการเรียนการสอน (เนื้อหา เหมือนกับแบบทดสอบก่อนการเรียนการสอน) ใช้เวลา 10 นาที บันทึกคะแนนสอบและแต้มเฉลี่ยสะสมของนิสิต ทั้ง 2 กลุ่ม นําผลที่ได้มาวิเคราะห์โดยใช้ค่าสถิติที (t-test) ในโปรแกรม SPSS for windows ที่ระดับนัยสําคัญทาง สถิติ p < 0.01 ประเมินบทเรียนคอมพิวเตอร์ช่วยสอน และทัศนคติต่อการเรียนด้วยบทเรียนคอมพิวเตอร์ในกลุ่มที่ 1 โดยใช้แบบสอบถามผล ค่าเฉลี่ยและส่วนเบี่ยงเบนมาตรฐานของแต้มเฉลี่ยสะสม และของคะแนนทดสอบก่อนการเรียนการสอนของนิสิต กลุ่มที่ 1 และ 2 มีค่า 2.79 + 0.40, 2.83 + 0.47 และ 11.66 + 2.20, 12.43 + 2.27 ตามลําดับ ไม่พบความ แตกต่างอย่างมีนัยสําคัญทางสถิติของแต้มเฉลี่ยสะสม และผลคะแนนสอบก่อนการเรียนการสอน ระหว่างกลุ่มที่ 1 และ 2 ค่าเฉลี่ยและส่วนเบี่ยงเบนมาตรฐาน ของคะแนนทดสอบภายหลังการเรียนการสอนของนิสิตกลุ่มที่ 1 และ 2 มีค่า 24.09 + 2.68 และ 22.26 + 2.29 ตามลําดับ พบความแตกต่างอย่างมีนัยสําคัญทางสถิติ (p<0.01) ของ คะแนนสอบภายหลังการเรียนการสอน ระหว่างกลุ่มที่ 1 และ 2 นิสิตร้อยละ 95 พอใจกับวิธีการเรียนโดยใช้บทเรียนคอมพิวเตอร์ สรุป การเรียนการสอนโดยใช้บทเรียนคอมพิวเตอร์ช่วยสอน ทําให้นิสิตมีความตั้งใจ สนใจ และเข้าใจ ในบทเรียน มากกว่าการเรียนการสอนโดยใช้แผ่นใสและภาพนิ่งเป็นสื่อประกอบการสอน
Evaluation Of The Success Of Adoptive Versus Passive Transfer Of Immunity Against Trypanosoma Cruzi, Karen Powell
Evaluation Of The Success Of Adoptive Versus Passive Transfer Of Immunity Against Trypanosoma Cruzi, Karen Powell
Masters Theses & Specialist Projects
Several investigators have demonstrated an increased resistance to the protozoal parasite Trypanosoma cruzi (the causative agent of Chagas' disease) in highly susceptible C3H mice when maintained at an environmental temperature of 36°C. This increased resistance is manifested as delay in onset of parasitemia, decreased parasitemia, decreased pathology, and increased longevity with eventual clearing of the parasite from the bloodstream. In addition, this enhanced resistance has been shown to be an immunologic phenomenon and not due to the direct effects of elevated temperature on the parasite itself. To ascertain the possible contributions of humoral vs. cellular immunity to the above phenomenon, …
Na/K-Atpase-Mediated 86rb+ Uptake And Asymmetrical Trophectoderm Localization Of Alpha1 And Alpha3 Na/K-Atpase Isoforms During Bovine Preattachment Development., D H Betts, L C Barcroft, A J Watson
Na/K-Atpase-Mediated 86rb+ Uptake And Asymmetrical Trophectoderm Localization Of Alpha1 And Alpha3 Na/K-Atpase Isoforms During Bovine Preattachment Development., D H Betts, L C Barcroft, A J Watson
Obstetrics & Gynaecology Publications
This study evaluated Na/K-ATPase alpha 1- and alpha 3-subunit isoform polypeptide expression and localization during bovine preattachment development. Na/K-ATPase cation transport activity from the one-cell to blastocyst stage was also determined by measuring ouabain-sensitive 86Rb+ uptake. Both alpha1- and alpha 3-subunit polypeptides were detected by immunofluorescence to encircle the entire cell margins of each blastomere of inseminated zygotes, cleavage stage embryos, and morulae. Immunofluorescent localization of alpha1-subunit polypeptide in bovine blastocysts revealed an alpha1 immunofluorescence signal confined to the basolateral membrane margins of the trophectoderm and encircling the cell periphery of each inner cell mass (ICM) cell. In contrast, alpha …
Effects Of Literacy Based Communication Intervention On Expressive Language Of A Young Child, Celeste C. Reynolds
Effects Of Literacy Based Communication Intervention On Expressive Language Of A Young Child, Celeste C. Reynolds
Undergraduate Honors Capstone Projects
A positive correlation has been demonstrated between improved expressive language skills and intervention using literacy related activities in the school-aged populations for both normally developing and developmentally delayed children. Norris (1991) found that children's literature provides meaningful contexts that are ideal for helping school aged children learn language in a manner that is interesting an does not artificially fragment language into subcomponents or splinter skills. Children can learn to recognize and use the abstract, complex, and subtle aspects of language in the context provided in written language. "The use of written language for intervention provides a context for integrating spoken …
Dentalgram - Vol. 12, No. 05, Loma Linda University School Of Dentistry
Dentalgram - Vol. 12, No. 05, Loma Linda University School Of Dentistry
Dentalgram
In this issue:
- Clinic With a Heart
- Kids' Care Fair
- Children visit LLUSD
- Ellis Jones retires
- Students win awards at CDA, CDHA conventions
- Student news
- Dental Hygiene '00 class named
- Employee of the Quarter
- Employee Appreciation
- Department news
- Pierre Fauchard Academy honors three
Being Alone: The Experience Of Elderly Homebound Females, Sharon Davis Burt Dnsc, Msn, Rn
Being Alone: The Experience Of Elderly Homebound Females, Sharon Davis Burt Dnsc, Msn, Rn
Dissertations
Elderly women comprise one of the fastest growing segments of the population in the United States. This growth is due in large part to increasing longevity, and a woman's life expectancy has now reached 79 years. However, along with those added years comes an increase in morbidity and a greater likelihood of living alone. This study describes the life experience of a specific group of elderly women, those who are homebound and living alone. When elderly women are included in research, the same combination of descriptors used for the participants in this study has not been incorporated. Consequently, while much …
Nudel, An Unusual Mosaic Protease Involved In Defining The Embryonic Dorsal-Ventral Axis Of Drosophila Melanogaster, Charles Chansik Hong
Nudel, An Unusual Mosaic Protease Involved In Defining The Embryonic Dorsal-Ventral Axis Of Drosophila Melanogaster, Charles Chansik Hong
Yale Medicine Thesis Digital Library
Dorsal-ventral polarity of the Drosophila embryo is determined by positional information that originates outside of the embryo. This information, which is created during oogenesis by the somatic follicle cells swrounding the oocyte, is utilized following fertilization to trigger a spatially regulated serine protease cascade in the extraembryonic perivitelline space. This protease cascade, which appears to be activated only on the presumptive ventral side of the embryo, generates the ligand for the Toll transmembrane protein that polarizes the embryo by inducing ventral development.This thesis presents evidence that nudel, a gene maternally required in somatic tissue for the formation of Toll's ligand, …
Heterologous Complementation Reveals That Mutant Alleles Of Qsr1 Render 60s Ribosomal Subunits Unstable And Translationally Inactive, Frederick A. Dick, Bernard L. Trumpower
Heterologous Complementation Reveals That Mutant Alleles Of Qsr1 Render 60s Ribosomal Subunits Unstable And Translationally Inactive, Frederick A. Dick, Bernard L. Trumpower
Dartmouth Scholarship
QSR1 is a highly conserved gene which encodes a 60S ribosomal subunit protein that is required for joining of large and small ribosomal subunits. In this report we demonstrate heterologous complementation of a yeast QSR1 deletion strain with both the human and corn homologs and show that the human and corn proteins are assembled into hybrid yeast/human and yeast/corn ribosomes. While the homologous genes complement lethality of the QSR1 deletion, they also result in a diminished growth rate. Analyses of the translation rates of ribosomes containing the human and corn proteins reveal a partial loss of function. Velocity gradient analyses …
Influence Of Boat Density Levels On Boaters' Satisfaction At Hyrum Lake, Utah, Floyd Alma Powell
Influence Of Boat Density Levels On Boaters' Satisfaction At Hyrum Lake, Utah, Floyd Alma Powell
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
The purpose of this study was to evaluate the effects of boat density on boaters' satisfaction at Hyrum Lake State Park, Utah. The study evaluated relationships between boaters' satisfaction with their Hyrum Lake experience and density of boats at different locations on the lake and among participants in different boating activities.
The participants in this study were boaters who used Hyrum Lake between May and September of 1996. An oral, on-site interview survey was randomly given to 282 boaters as they left the lake for the day. The surveys were conducted on high-density days (weekends) and low-density days (weekdays), which …
Quantal Mechanisms Underlying Stimulation-Induced Augmentation And Potentiation, Hong Cheng
Quantal Mechanisms Underlying Stimulation-Induced Augmentation And Potentiation, Hong Cheng
Electronic Theses and Dissertations
Repetitive stimulation of motor nerves causes an increase in the number of packets of transmitter ("quanta") that can be released in the ensuing period. This represents a type of conditioning, in which synaptic transmission may be enhanced by prior activity. Despite many studies of this phenomenon, there have been no investigations of the quantal mechanisms underlying these events, due to the rapid changes in transmitter output and the short time periods involved. To examine this problem, a method was developed in which estimates of the quantal release parameters could be obtained over very brief periods (3 s). Conventional microelectrode techniques …
The Baculovirus Anti-Apoptotic P35 Protein Promotes Transformation Of Mouse Embryo Fibroblasts., M Resnicoff, B. Valentinis, D. Herbert, D. Abraham, P D. Friesen, E. S. Alnemri, R Baserga
The Baculovirus Anti-Apoptotic P35 Protein Promotes Transformation Of Mouse Embryo Fibroblasts., M Resnicoff, B. Valentinis, D. Herbert, D. Abraham, P D. Friesen, E. S. Alnemri, R Baserga
Department of Microbiology and Immunology Faculty Papers
The baculovirus p35 protein is a potent inhibitor of programmed cell death induced by a variety of stimuli in insects, nematodes, and mammalian cell lines. The broad ability of p35 in preventing apoptosis has led us to investigate its effect on mouse embryo fibroblasts in vitro and in vivo. For this purpose, we have used R- cells (3T3-like fibroblasts derived from mouse embryos with a targeted disruption of the insulin-like growth factor I receptor (IGF-IR) genes) and R508 cells (derived from R- and with 15 x 10(3) IGF-IRs per cell). Both cell lines grow normally in monolayer, but they do …
The Sequential Role Of Lymphotoxin And B Cells In The Development Of Splenic Follicles, Mercedes Gonzalez, Fabienne Mackay, Jeffrey L. Browning, Marie H. Kosco-Vilbois, Randolph J. Noelle
The Sequential Role Of Lymphotoxin And B Cells In The Development Of Splenic Follicles, Mercedes Gonzalez, Fabienne Mackay, Jeffrey L. Browning, Marie H. Kosco-Vilbois, Randolph J. Noelle
Dartmouth Scholarship
The transfer of lymphocytes into severe combined immunodeficiency (SCID) mice induces a series of histological changes in the spleen, including the appearance of mature follicular dendritic cells (FDCs). Studies were undertaken to clarify the role of lymphotoxin (LT) in this process. The results show that SCID mice have a small and partially differentiated white pulp containing marginal zone and interdigitating dendritic cells, but lacking FDCs. Transferred spleen cells can segregate into T and B cell areas shortly after their injection to SCID mice. This ability is dependent on signaling through LT-β receptor (LT-βR), since blocking ligand–receptor interaction in recipient SCID …
The Second Messenger Camp Elicits Eating By An Anatomically Specific Action In The Perifornical Hypothalamus, Gillard, Arshad Khan, Rickinder Grewal, Bara Mouradi, Stefany Wolfsohn, B. Stanley
The Second Messenger Camp Elicits Eating By An Anatomically Specific Action In The Perifornical Hypothalamus, Gillard, Arshad Khan, Rickinder Grewal, Bara Mouradi, Stefany Wolfsohn, B. Stanley
Departmental Papers (Biology)
No abstract provided.
Nsu Going Back May Be The Best Way Of Getting Ahead Courses, Seminars, Workshops, Conferences Spring 1998, Nova Southeastern University
Nsu Going Back May Be The Best Way Of Getting Ahead Courses, Seminars, Workshops, Conferences Spring 1998, Nova Southeastern University
Abraham S. Fischler College of Education and School of Criminal Justice College Archive
No abstract provided.
Allopurinol As An Additive To Quinine In The Treatment Of Acute Complicated Falciparum Malaria, P. S. A. Sarma, Anil K. Mandal, Harry Khamis
Allopurinol As An Additive To Quinine In The Treatment Of Acute Complicated Falciparum Malaria, P. S. A. Sarma, Anil K. Mandal, Harry Khamis
Population and Public Health Sciences Faculty Publications
The emergence of chloroquine resistance, and a world-wide scarcity of quinine, have resulted in a search for newer antimalarial drugs directed against falciparum malaria. Allopurinol causes virtually complete inhibition of purine biosynthesis of malaria parasites, which may prove lethal to the parasites. This study was designed to examine if allopurinol is additive to quinine in the treatment of acute falciparum malaria. Forty-seven Asian-Indian adults with acute complicated falciparum malaria were assigned to a treatment period of five days. They were randomly assigned to receive either oral allopurinol (12 mg/kg in three divided doses for five days) plus quinine (600 mg …
Oncolog, Volume 43, Number 04, April 1998, Sunita Patterson, Sunni Hosemann, Alison Ruffin, Mitchell Morris Md
Oncolog, Volume 43, Number 04, April 1998, Sunita Patterson, Sunni Hosemann, Alison Ruffin, Mitchell Morris Md
OncoLog MD Anderson's Report to Physicians (All issues) Archives
- Molecular research leads to clinical trials for bladder cancer
- Patients to test exercise theory in quality-of-life study
- Practice guidelines and collaborative paths point the way
- Protocols: Bladder Cancer Clinical Trials Interventions Span Surgery, Chemotherapy, Radiotherapy, and Genetic Manipulation
- DiaLog: The New Math of Today’s Health Care, by Mitchell Morris, MD, Vice President for Information and Health Care Systems
The Changing World Of Genetics And Abortion: Why The Women's Movement Should Advocate For Limitations On The Right To Choose In The Area Of Genetic Technology, Renee C. Esfandiary
The Changing World Of Genetics And Abortion: Why The Women's Movement Should Advocate For Limitations On The Right To Choose In The Area Of Genetic Technology, Renee C. Esfandiary
William & Mary Journal of Race, Gender, and Social Justice
No abstract provided.
Yale Nurse: Yale School Of Nursing Newsletter, April 1998, Yale University School Of Nursing
Yale Nurse: Yale School Of Nursing Newsletter, April 1998, Yale University School Of Nursing
Yale School of Nursing Alumni Newsletters and Magazines
This issue includes part two of a two-part series, Graduate Entry Program in Nursing (GEPN): A Twenty-Year History.
Please contact the Medical Historical Library if you need a higher resolution version.
Nsu Going Back May Be The Best Way Of Getting Ahead Courses, Seminars, Workshops, Conferences Spring 1998, Nova Southeastern University
Nsu Going Back May Be The Best Way Of Getting Ahead Courses, Seminars, Workshops, Conferences Spring 1998, Nova Southeastern University
Abraham S. Fischler College of Education and School of Criminal Justice College Archive
No abstract provided.
Antigen-Specific Cd8+ T Cells Protect Against Lethal Toxoplasmosis In Mice Infected With Neospora Caninum, Lloyd H. Kasper, Imtiaz A. Khan
Antigen-Specific Cd8+ T Cells Protect Against Lethal Toxoplasmosis In Mice Infected With Neospora Caninum, Lloyd H. Kasper, Imtiaz A. Khan
Dartmouth Scholarship
Neospora caninum is a coccidial protozoan parasite that appears morphologically indistinguishable from Toxoplasma gondii and that infects a large range of mammals. Both inbred and outbred strains of mice exhibit a high degree of resistance to infection with N. caninum. Three inbred strains of mice (A/J, BALB/c, and C57BL/6) that were infected intraperitoneally with N. caninum were protected against a lethal challenge from T. gondii. Vaccine-induced protection was Neospora dose dependent. A rise in the CD8+ T-cell population in mice that had been vaccinated with N. caninum and challenged with T. gondii was observed. Adoptive transfer of CD8+ T-cell splenocytes …
Acute Blood Pressure Responses To Static And Dynamic Exercise: Racial Differences, Reuben Leon Wright
Acute Blood Pressure Responses To Static And Dynamic Exercise: Racial Differences, Reuben Leon Wright
Theses and Dissertations in Urban Services - Urban Education
African Americans have a higher incidence of hypertension than other racial groups. Furthermore, some research suggests that normotensive individuals who exhibit exaggerated blood pressure (BP) responses to exercise may be at risk for future hypertension. This study sought to determine if normotensive African Americans exhibited exaggerated BP responses to static exercise or dynamic exercise relative to Caucasian Americans and Asian Americans. Thirty normotensive subjects participated from each of the three racial groups (15 males and 15 females). Subjects held 30% of maximal voluntary contraction (right knee extension) for 3 minutes, and BP was recorded during the third minute. On a …
Developmental And Hormonal Regulation Of The Expression Of Cytosolic Phospholipase A2 Protein Levels In Baboon Placenta, Kathleen Elizabeth Dunstan
Developmental And Hormonal Regulation Of The Expression Of Cytosolic Phospholipase A2 Protein Levels In Baboon Placenta, Kathleen Elizabeth Dunstan
Chemistry & Biochemistry Theses & Dissertations
Cytosolic phospholipase A2 ( cPLA2) specifically catalyzes the release of arachidonate from membrane phospholipids, thus initiating synthesis of prostaglandins, thromboxanes, and other eicosanoids. The human and nonhuman primate placenta actively synthesize high levels of eicosanoids which play both an autocrine and paracrine role in placental function. Previous studies in Dr. Miriam D. Rosenthal's laboratory have shown that cPLA2 mRNA levels are developmentally regulated. The present study was designed to determine whether placental cPLA2 protein levels increased during gestation. Since the marked increases in estrogen levels during normal pregnancy have been shown to enhance morphological and …
The Role Of Glycoconjugates In Mediating Human Fertilization And Induction Of Fetomaternal Tolerance, Manish S. Patankar
The Role Of Glycoconjugates In Mediating Human Fertilization And Induction Of Fetomaternal Tolerance, Manish S. Patankar
Theses and Dissertations in Biomedical Sciences
Using the hemizona assay (HZA), a in vitro sperm-egg binding assay, we show that specific glycoconjugates known to inhibit immune cell interactions mediated by the selectins, potently block human sperm-egg binding. The selectin ligand sialyl Lewisx inhibits sperm binding in the HZA by 60% at a concentration of 1 mg/ml. Our data indicates that glycodelin-A, a endometrial glycoprotein known to block sperm-egg binding in the HZA at low concentrations expresses unusual fucosylated lacdiNAc type glycans. The fucosylated lacdiNAc type sugars have been previously shown to be 15-20 fold more potent ligands of E-selectin. Glycodelin-S a seminal plasma glycoform of …
Mathematical Models Of Tumors And Their Remote Metastases, Carryn Bellomo
Mathematical Models Of Tumors And Their Remote Metastases, Carryn Bellomo
Mathematics & Statistics Theses & Dissertations
Clinical observations and indications in the literature have led us to investigate several models of tumors. For example, it has been shown that a tumor has the ability to send out anti-growth factors, or inhibitors, to keep its remote metastases from growing. Thus, we model the depleting effect of such a growth inhibitor after the removal of the primary tumor (thus removing the source) as a function of time t and distance from the original tumor r.
It has also been shown clinically that oxygen and glucose are nutrients critical to the survival and growth of tumors. Thus, we model …
Enhancement Of Atp Levels And Glucose Metabolism During An Infection By Chlamydia: Nmr Studies Of Living Cells, David M. Ojcius, H. Degani, Joel Mispelter, Alice Dautry-Varsat
Enhancement Of Atp Levels And Glucose Metabolism During An Infection By Chlamydia: Nmr Studies Of Living Cells, David M. Ojcius, H. Degani, Joel Mispelter, Alice Dautry-Varsat
All Dugoni School of Dentistry Faculty Articles
The Chlamydia species are obligate intracellular bacteria that proliferate only within the infected cell. Since the extracellular bacteria are metabolically inert and there are no cell-free systems for characterizingChlamydia metabolism, we studied metabolic changes related to ATP synthesis and glycolysis in HeLa cells infected withChlamydia psittaci during the course of the 2-day infection cycle using noninvasive 31P and 13C NMR methods. We find that the infection stimulates ATP synthesis in the infected cell, with a peak of ATP levels occurring midway through the infection cycle, when most of the metabolically active bacteria are proliferating. The infection also stimulates synthesis of …
Predictors Of Children’S Risk Appraisals, David Dilillo, Richard Potts, Susan Himes
Predictors Of Children’S Risk Appraisals, David Dilillo, Richard Potts, Susan Himes
Department of Psychology: Faculty Publications
This study explored variables associated with cognitive appraisals of physical risk in a sample of 62 elementary school children. Participants were presented with drawings of persons in three categories of risky situations typical of children, typical of adults, and typical of television plots. They were asked to judge the potential for physical injury in each. Results indicated that children tended to appraise risks in child, adult, and TV-plot risk situations differently, and that each type of situation was predicted by different variables. For the child situations, greater amounts of direct experience with the risk situation itself was found to be …
What's Happening: March 4, 1998, Maine Medical Center
What's Happening: March 4, 1998, Maine Medical Center
What's Happening
No abstract provided.
Jefferson Alumni Bulletin – Volume Xlvii, Number 2, March 1998
Jefferson Alumni Bulletin – Volume Xlvii, Number 2, March 1998
The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)
Jefferson Alumni Bulletin – Volume XLVII, Number 2, March 1998
Department Restructurings Respond to the Evolution in Scientific Disciplines, Page 4
The Rb2/p130 Gene and Endometrial Cancer, Page 7
Gene Therapy Trial for Glioblastoma, Page 8
Ovarian Cancer Vaccine is Promising in First Tests, Page 9
Transgenic Mouse for Study of Photoaging, Page 10
Uric Acid Reduces MS Symptoms in Mice, Page 11
Albert Einstein Healthcare Network Will Join Jefferson Health System by July, Page 12
Proposed Amendments to Alumni Association Bylaws, Page 14
Joseph Seltzer, ’71, the Next Alumni President, Page 15
Wallace Miller ’56 Receives RSNA Gold Medal, …