Digital Commons Network^™

Susceptibility At High Inoculum Of Penicillin-Resistant Staphylococcus Aureus To Six Cephalosporins, Andres Suarez, Ramon Del Busto, Edward L. Quinn, Donald Pohlod

Henry Ford Hospital Medical Journal

Six cephalosporins (currently available for clinical use or undergoing clinical trials) were tested by tube dilution method against high inoculum (10⁷ colony forming units) of 37 strains of penicillin resistant Staphylococcus aureus. 3.1 μg/ml of cephalothin inhibited 100% of strains while higher concentrations of cefoxitin, cephapirin, cefamandole, cephalexin and cephradine were required. The percent of strains with minimal inhibitory concentration higher than 3.1 μg/ml ranged between 10.8% (cefoxitin) and 100% (cephradine). These findings support the observation that cephalothin is less susceptible to inactivation than the other cephalosporins. Although the exact clinical implication of these findings has not been established, …

Miliary Tuberculosis And Disseminated Intravascular Coagulation: A Case Report, Mohsin Alam, George Bower

Henry Ford Hospital Medical Journal

A case of miliary tuberculosis complicated by respiratory insufficiency and disseminated intravascular coagulation was treated successfully with antituberculosis drugs, ventilatory support, and heparin, packed red cells, platelet transfusions and plasma. Tuberculosis is a rare cause of disseminated intravascular coagulation.

High Dose In-Continuity Irradiation Of Para-Aortic And Pelvic Nodes For Carcinoma Of The Prostate. The First Three-And-One-Half Years, Joel Elliot White, Murray Boles

Henry Ford Hospital Medical Journal

A technique for treating the para-aortic nodes to a high dose of irradiation in continuity with the pelvis has been developed at Henry Ford Hospital and recently described by one of the authors. The "nine-field technique" was initially used in late 1973 to treat two patients with advanced prostatic carcinoma who had grossly involved para-aortic nodes. Since that time, 16 additional patients with carcinoma of the prostate, one patient with carcinoma of the urinary bladder, and one patient with carcinoma of the cervix have been treated by this technique. This paper analyzes sequelae and complications of the technique and mentions …

Osteogenic Sarcoma: Report Of One Hundred And Fifty-Seven Cases, Kent K. Wu, Edwin R. Guise, Harold M. Frost, C. Leslie Mitchell

Henry Ford Hospital Medical Journal

This study presents the clinical features, roentgenographic manifestations, pathological features, abnormal laboratory studies, treatment and prognosis of 157 cases of osteogenic sarcoma. The series is the fifth largest ever reported. The authors favor prompt surgical ablation followed by controlled intensive chemotherapy as a prophylactic or combined chemotherapy and radiation therapy for metastatic osteogenic sarcoma. All case reports but one present rare or unusual situations.

In Memoriam: Robert C. Horn, Jr., M.D., Gerald Fine, John W. Rebuck

Henry Ford Hospital Medical Journal

No abstract provided.

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Vital Signs, December, 1976, Boonshoft School Of Medicine

Vital Signs

A four page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, a research spotlight, alumni notes, and more.

Digest Of The Philadelphia College Of Osteopathic Medicine (December 1976), Philadelphia College Of Osteopathic Medicine

Digest

The December 1976 issue of the Digest of the Philadelphia College of Osteopathic Medicine includes the following articles:

• Dr. Frederic H. Barth
• The Osteopathic Spirit of '76
• News from the College
• Christmas at PCOM
• A Funny Thing Happened
• New Appointments
• Harrisburg Museum
• Alumni News Briefs
• Life Membership in PCOM's AA
• List of Life Members and Lost Alumni
• In Memoriam
• ACAOP in New Orleans
• People
• Faculty Notes
• Committees

Vital Signs, November, 1976, Boonshoft School Of Medicine

Vital Signs

A six page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, a research spotlight, alumni notes, and more.

Newsletter, Volume 21, Number 06, November - December 1976

Newsletter: A Report to Physicians of Texas Archives

• First Lady at Dedication
• Carcinogenic Effects of Anesthetics Studied
• Cancer: A Comprehensive Treatise Published
• Patients Helped at Cancer Rehabilitation Center
• Research Institute Renamed
• Two Meetings in January

Subvalvular Aortic Stenosis Associated With Dynamic Outflow Tract Obstruction: A Case Report, Armando Cesar Madrazo, Daniel T. Anbe, James J. Karo, Peter Torbey, Ellet H. Drake, Fareed Khaja, Sidney Goldstein

Henry Ford Hospital Medical Journal

Hemodynamic and angiographic findings are described in a 27-year-old patient, who had undergone surgical operation for subvalvular membranous aortic stenosis. Left ventriculography revealed persistence or regrowth of the subvalvular fibrous ring, and hemodynamic data revealed associated dynamic obstruction of the left ventricular outflow tract. The authors emphasize the importance of uncovering associated dynamic obstruction by provocative maneuvers and use of Beta blockers.

Front Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Prolonging Oxygen Consumption During Preservation Of Canine Kidneys By The Addition Of Continuous Dialysis, Daniel Dall'olmo, Stanley G. Dienst

Henry Ford Hospital Medical Journal

Kidneys were preserved by continuous pulsatile perfusion and their metabolic rate monitored by O2 consumption. Experiments were carried out to determine if dialyzing the perfusate to supply metabolic substrates would aid in kidney preservation. A control group was compared against two experimental groups at 25°C. Average preservation time before fall off of oxygen consumption differed for each group: control - 8 hours, dialysis with amino acids - 6 hours, dialysis with amino acids and cofactors - 11 hours. Results indicated that, if suitable concentrations of metabolic substrates and cofactors were used, the preserved kidneys maintained higher levels of O2 consumption …

Oral Contraceptives And Myocardial Infarction: Report Of Three Cases And Review Of The Literature, Mohsin Alam, Remigio Garcia, Ellet H. Drake

Henry Ford Hospital Medical Journal

Three cases are presented of young women who had myocardial infarctions possibly due to coronary thrombosis related to oral contraceptive therapy. These patients had none or very few risk factors for coronary artery disease. In two of the patients, selective coronary arteriograms showed normal results on the third and tenth week after the diagnosis was established. The pathogenesis of coronary artery thrombosis in patients receiving oral contraceptives containing estrogen is still controversial, but it appears to be the result of its multifactorial effect on the platelets, coagulation factors, vessel wall, blood pressure, postprandial blood sugar and abnormalities of lipid metabolism.

A Screening, Referral, And Follow-Up Program For High Blood Pressure At Henry Ford Hospital: Part Ii. Results Of Referral And Follow-Up, John C. Erfurt, Andrea Foote, John R. Caldwell

Henry Ford Hospital Medical Journal

This is the second of two articles on the Henry Ford Hospital screening, referral, and follow-up program for high blood pressure. The first reported on the screening results of the program, along with associated epidemiological findings. This article presents the results of referral and follow-up. During the period of March 27 through December 11, 1975, 808 people were screened; 196 (24%) were found to have uncontrolled high blood pressure and were referred to physicians for diagnosis and possible treatment for hypertension. The program is currently following up with these people and their physicians to insure successful referral and maintenance of …

Penetrating Abdominal Trauma: A Morbidity And Mortality Report Of A Growing Social Problem, F. Samhouri, C. Grodsinsky, T. A. Fox Jr.

Henry Ford Hospital Medical Journal

The management of penetrating abdominal wounds has become a necessity in most larger metropolitan hospitals. Most of these wounds are produced by low velocity gunshots, but some are stab wounds. Several recent advances have contributed to the more successful management of penetrating abdominal wounds. These include: 1) improvement in on-site care by various emergency medical services, 2) more rapid transportation of the injured to a facility equipped to care for such patients, 3) vigorous resuscitative and diagnostic measures, 4) prompt and adequate surgical intervention, 5) improvements in anesthesia techniques, and 6) improvements in blood banks. From 1969 to 1974, 843 …

Use Of The Weibull Distribution For Analysis Of A Clinical Therapeutic Study In Rheumatoid Arthritis, W. R. Mccrum, J. T. Sharp, G. B. Bluhm

Henry Ford Hospital Medical Journal

This paper introduces the use of the Weibull distribution function for the analysis of small samples of clinical data. It is compared with the use of the conventional analysis of variance in determining the results of a study comparing the use of gold salts and a placebo in the treatment of rheumatoid arthritis. Although the samples were small, 14 control patients and 13 who were treated, analysis of variance determined several significant differences between the two groups. The use of the Weibull distribution, however, not only confirmed these differences, but also determined several more differences between the two groups that …

Publications Of The Staff Of The Henry Ford Hospital And The Edsel B. Ford Institute For Medical Research

Henry Ford Hospital Medical Journal

No abstract provided.

Vital Signs, September/October, 1976, Boonshoft School Of Medicine

Vital Signs

An eight page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, a research spotlight, alumni notes, and more.

Digest Of The Philadelphia College Of Osteopathic Medicine (September 1976), Philadelphia College Of Osteopathic Medicine

Digest

The September 1976 issue of the Digest of the Philadelphia College of Osteopathic Medicine includes the following articles:

• The Class of 1980
• Registration Day 1976
• Convocation
• Open House
• News from the College
• V.I.A. for Students
• PCOM's Rural Health Care Center
• Neuronsensory Unit Reorganized
• News from the Hospital And Health Care Centers
• Greenwood Medical Center
• People
• CME Programs
• Letters
• New Appointments
• Faculty Notes
• Alumni News Briefs
• In Memoriam
• Alumni Board

Newsletter, Volume 21, Number 05, September - October 1976

Newsletter: A Report to Physicians of Texas Archives

• New Complex Dedicated
• Dental Oncology Department Created
• Board of Visitors Aids MDAH
• New Facilities Expand Patient Services
• Cancer Treatment Policy
• UICC Provides Directory of Facilities
• Advisory Committee of New Carcinogenesis Center Meets
• Bone Marrow Transplantation
• Gynecologic Oncology

Correspondence, Paul Star, Dean Of Student Life To William Bergen, D.O., 1976 August 10, Paul Star

William F. Bergen, D.O. Collection

Letter from Paul Star, Dean of Students to William Bergen, with the contract for the College physician position for the 1976-77 academic year.

Sideroblastic Anemias, Louis D. Saravolatz

Henry Ford Hospital Medical Journal

Sideroblastic anemias are reviewed with emphasis on clinical features, biochemical studies, treatment modalities and prognosis. A classification of these anemias based on etiology is also provided.

Vital Signs, July, 1976, Boonshoft School Of Medicine

Vital Signs

A four page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, a research spotlight, alumni notes, and more.

Newsletter, Volume 21, Number 04, July - August 1976

Newsletter: A Report to Physicians of Texas Archives

• Thermography and Mammography Evaluated – Breast Cancer Detection Techniques
• Dr. Clark Supports National Cancer Institute
• MDAH Facts
• Dedication Planned
• Large Bowel Cancer Exhibit
• Pediatrics Workshop Held

A Screening, Referral, And Follow-Up Program For High Blood Pressure At Henry Ford Hospital: Part I. Results Of Screening, Andrea Foote, John C. Erfurt, John R. Caldwell

Henry Ford Hospital Medical Journal

Data are reported on the screening results from the Henry Ford Hospital screening, referral and follow-up program for high blood pressure. The report covers the period of March 27 through December 11, 1975, during which time 808 people were screened in the hospital lobby. Thirty-nine percent were found upon initial screening to have high blood pressure readings or previously diagnosed hypertension. Of these people, 70% were already under treatment for hypertension, but only 21% showed adequate blood pressure control (with readings below 140/90 mm Hg). Those with high readings were referred to their physicians. A paper on the results of …

Susceptibility Of Clinical Isolates Of Bacteria To Cefamandole, Cefoxitin And Cephalothin, R. Del Busto, A. Suarez, E. Quinn, D. Pohlod

Henry Ford Hospital Medical Journal

The in vitro susceptibility was determined of 274 isolates to cephalothin and two new antibiotics, cefamandole and cefoxitin. Cefamandole was comparable to cephalothin in preventing growth of cultures of the gram positive organisms except for penicillin-resistant Staphylococcus aureus which was more sensitive to cephalothin. Cefamandole was more active than cephalothin against all the gram negative bacteria including Haemophilus influenzae and in addition it was active against many strains of Enterobacter sp. Cefoxitin was less active than cephalothin against the gram positive organisms but it was more active against most of the gram negative bacteria. In addition. It was active against …

Front Matter

Henry Ford Hospital Medical Journal

No abstract provided.

The Association Of Acute Cerebellar Encephalopathy And Neuroblastoma, M. Reza Jahadi, John G. Whitcomb, Ratnaker Kini, Robert H. High

Henry Ford Hospital Medical Journal

Acute cerebellar encephalopathy is a rare neurological disorder associated with neuroblastoma and is characterized by ataxia, somatic myoclonus and opsoclonus. The pathogenesis which underlies the relationship between the two conditions is obscure. One patient with neuroblastoma and acute cerebellar encephalopathy Is reported. The occurrence of neuroblastoma and acute cerebellar encephalopathy In this case may be coincidental but, on the basis of frequent recent reports of this association, a possible relationship between these two entities is entertained. It is therefore recommended that all patients with acute cerebellar encephalopathy be surveyed for unapparent neuroblastoma. The search should include chest and skeletal X-rays, …

Immunological Aspects Of Neoplastic Diseases, V. Radhakrishna

Henry Ford Hospital Medical Journal

The immunological approach to neoplastic disease is gaining favor because malignant tumors are associated with immunodeficient states. Mesenchymal tumors have been seen in renal allograft recipients. The discovery of carcinoembryonic antigen, alfafetoprotein and other protein antigens associated with malignant diseases are other factors. Spontaneous regression of malignant neoplasm has been attributed to an effective immunologic process in the host. Identification of tumor specific antigens may explain these spontaneous tumor regressions. It may not be too optimistic to expect tumor vaccine of some sort within the next few years. B.C.G. and other nonspecific immunostimulants are under investigation for treatment of malignant …