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Henry Ford Hospital Medical Journal

No abstract provided.

Psychocardiologic Perspectives Of Coronary Artery Disease, Richard Ketai

Henry Ford Hospital Medical Journal

The importance of mind, emotion, and behavior as they relate to the heart, particularly coronary artery disease, is growing in recognition. A review of the research shows increasingly sophisticated demonstrations of links unifying heart function and mind. "Psychocardiology" would be an appropriate term for the diverse areas of interest which focus on the psychosocial correlates of heart disease. This paper illustrates this concept through a review of psychosocial and behavioral aspects of coronary artery disease.

Biogenesis Of The Platelet Receptor For Fibrinogen: Evidence For Separate Precursors For Glycoproteins Iib And Iiia., Paul F. Bray, Jean-Philippe Rosa, Vishwanath R. Lingappa, Yuet W. Kan, Rodger P. Mcever, Marc A. Shuman

Cardeza Foundation for Hematologic Research

Congenital absence of platelet glycoproteins IIb and IIIa (GPIIb and GPIIIa) results in a severe bleeding disorder characterized by defective platelet aggregation and failure of fibrinogen to bind to platelets. GPIIb is a two-chain protein containing disulfide-linked alpha and beta subunits. GPIIb and GPIIIa are present as a heterodimeric, noncovalent complex in the platelet plasma membrane and function as the fibrinogen receptor. To characterize synthesis of these two proteins, RNA isolated from a human leukemia cell line that contains GPIIb and GPIIIa was translated in a wheat germ cell-free system. Polyclonal antibodies specific for each protein immunoprecipitated distinct [35S]methionine-labeled precursors, …

Low Toxicity Radiation Sensitizer, Barton L. Bergquist, James C. Chang

Patents (University of Northern Iowa)

This invention relates to cisplatin type fluorescently labeled compounds. In particular, the compounds are bis (5-aminofluorescein)-dichloroplatinum (II) or certain substituted analogues thereof. The compounds are useful as radiation sensitivity enhancers and as fluorescent biological tracers. The invention also relates to a unique, single step synthesis for preparing said compounds.

The Effect Of Intraperitoneally Administered Thyroxine, Thiidothyronine And Iopanoic Acid On The In Vivo And In Vitro Oxygen Consumption Rates Of Normal (C57bl/Ksj Db/M) And Diabetic (C57bl/Ksj Db/Db) Mice, A. Kay. Kalousek

Theses Digitization Project

No abstract provided.

Early Soft Signs And Later Psychopathology, David Shaffer, Cornelius Stokman, Patricia A. O'Connor, Stephen Shafer, Joseph E. Barmack, Suzanne Hess, D. Spalten, Irvin Sam Schonfeld

Publications and Research

At age 17 two motor signs, mirror movements and dysdiadochokinesis, were found in more than half the subjects known to have had the respective signs at age 7. These rates were significantly higher than rates found within the group of subjects who were sign free at age 7.

Vital Signs, Winter 1986, Boonshoft School Of Medicine

Vital Signs

A twenty eight page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, alumni profiles, class notes, and more.

Oncolog, Volume 31, Number 02, April-June 1986, Ralph S. Freedman Md, Phd, Elton Stubblefield Phd

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• Conference Report: Gynecologic Cancer Outcome Improves Because of New Treatment Applications
• A Geneticist's View of Cancer: New Insight from Developmental Mechanisms
• Counseling, Practical Advice Help Women with Cervical Cancer Resume Sexual Activity

Oncolog, Volume 31, Number 03, July-September 1986, Staff

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• Learning How and Why Drugs Kill Cells Is Chemotherapy Researchers' Prime Goal
• Cancer Prevention Begins at Home: With MDA Screening and Detection Clinic
• Grant Taylor Organized First Collaborative Drug Research Group in This Part of the Country

Oncolog, Volume 31, Number 01, January-March 1986, Lester J. Peters Md

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• From Ability to Measure Cell Survival Come New Radiotherapeutic Strategies
• Diagnosing the Rare Lesion: Ovarian and Omental Ependymomas
• Radiotherapy Tailored to Patient's Disease

Oncolog, Volume 31, Number 04, October-December 1986, Bruce M. Boman Md, Phd, Frances M. Davis Phd

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• Hereditary Colon Cancer: Molecular Research and Family Studies Aim for Early Detection
• Bone Marrow Transplantation Success Brings Patients and Physicians to Reunion
• Houston-Galveston Hybridoma Researchers Review Laboratory and Clinical Progress

Orbital Metastasis With Enophthalmos: A Review Of The Literature, David M. Reifler

Henry Ford Hospital Medical Journal

Orbital metastasis is associated with enophthalmos in up to one third of all cases. After analyzing the clinical and pathologic features In 25 reported cases of enophthalmic orbital metastasis, the condition was found to almost exclusively affect females, usually in the 60 to 70 age group. The right orbit was the most commonly affected. The primary lesion was located in the breast in 19 (76%) cases and in the abdomen in 6 (24%) cases. In one third of the cases, the manifestations of the orbital metastasis were recognized before diagnosing the primary lesion. The most common presenting features were diplopia …

Primary Hyperparathyroidism: Changing Patterns In Presentation And Treatment Decisions In The Eighties, D. Sudhaker Rao

Henry Ford Hospital Medical Journal

No abstract provided.

The Pseudo-Leukocyte-Specific/Nuclear Membrane Antinuclear Antibody Pattern: A Puzzle, Thomas K. Burnham

Henry Ford Hospital Medical Journal

We report an antinuclear antibody (ANA) pattern—the pseudo-leukocyte-specific/nuclear membrane (PLS/NM) ANA pattern—that is puzzling because it usually reacts with only a few cells on human spleen imprints but with most epidermal and numerous dermal nuclei of normal human skin sections. The designation "pseudo-leukocyte-specific" was chosen because it is generally seen in only a few nuclei on human spleen imprints, thereby resembling the true leukocyte-specific ANA pattern. A few small round nuclei fluoresce homogeneously, surrounded by a bright wall, suggesting nuclear membrane (NM) fluorescence. The term "nuclear membrane" was added to the name because the NM appearance is even more prominent …

Clinical Trials: Ii. Randomization And Sample Size, Barbara Tilley, Anthony Schork

Henry Ford Hospital Medical Journal

This second in a series of articles focuses on clinical trials. Information is provided on determining sample size and on methods of randomization including simple and single- and double-consent randomization, and blocked, stratified, and adaptive procedures to randomize patients to a study group.

Results Of A Head And Neck Examination: Evaluation Of A Tumor Of The Floor Of The Mouth, Caren M. Barnes, Kenneth W. Nelson, Gary H. Conover

College of Dentistry: Faculty Publications

This article reviews a solitary, well-defined tumor of the floor of the mouth. The tumor presented as a raised, elevated, sessile mass that was freely movable and soft to. the touch. The case illustrates the importance of performing a thorough head and neck examination, and formulating a differential diagnosis if any abnormality is detected. The clinical features, histopathology and responsibility of the dental hygienist in performing a thorough head and neck examination is reviewed.

Vital Signs, Fall 1985, Boonshoft School Of Medicine

Vital Signs

A twenty eight page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, alumni profiles, class notes, and more.

The Effectiveness Of Stimulation Therapy For The Cognitively Impaired Elderly, Sylvia H. Old

Community & Environmental Health Theses & Dissertations

The effectiveness of stimulation therapy for the cognitively impaired elderly living in an institution was assessed. Residents with varying degrees of cognitive impairment were treated with twenty, thirty-minute daily periods of reality orientation, reminiscence, resocialization, remotivation, and other stimulating therapies and were compared with a control group_ receiving no intervention. Treatment effects were assessed with a variety of instruments reflecting functioning across several domains. Included were ability to perform both basic self-care functions and activities of daily living, cognitive performance, affect, and satisfaction with the care received and the living environment in the nursing home. The experimental group was divided …

Current Concepts Of Metabolic Functional Imaging With Positron Emitters, John W. Keyes Jr.

Henry Ford Hospital Medical Journal

Positron emitting radionuclides have unique properties that make them nearly ideal as radioactive tracers for in vivo metabolic studies. Using positron emission tomographic (PET) scanning and positron-labeled radiopharmaceuticals, one can study local glucose metabolism in tissues, blood flow, oxygen utilization, protein synthesis, and many other functions noninvasively in normal subjects and patients who have various diseases. A review of some of these techniques and the relative advantages and problems associated with the PET approach is presented.

Nuclear Magnetic Resonance: Current And Future Clinical Applications, Jerry W. Froelich, David O. Hearshen, Robert D. Halpert, Suresh Patel

Henry Ford Hospital Medical Journal

Nuclear magnetic resonance has evolved from a laboratory analytical tool to become a rapidly developing discipline in clinical medicine. We present a brief historical overview, an introduction to the basic principles of the phenomenon, and a statement of the current status of clinical imaging. We have elected to use the traditional terminology nuclear magnetic resonance to refer to the imaging component of the field rather than the American College of Radiology (ACR) modification magnetic resonance. We do this out of respect for the founders of the field.

Digest Of The Philadelphia College Of Osteopathic Medicine (Spring 1985), Philadelphia College Of Osteopathic Medicine

Digest

The Spring 1985 issue of the Digest of the Philadelphia College of Osteopathic Medicine includes the following articles:

• The President's Page
• The 94th Commencement
• Commencement Photos
• Master of Science Degrees Conferred
• Commencement Award Winners
• Families
• The Class of 1985 and Internship Hospitals
• Faculty Notes
• New Appointments
• News from the OMCP
• From the Alumni Office
• Alumni News Briefs
• Nurses Alumnae Biennial Banquet
• In Memoriam
• Coming Events

Vital Signs, Spring 1985, Boonshoft School Of Medicine

Vital Signs

A twenty eight page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, alumni profiles, class notes, and more.

Dr Frank J. Sladen: The Osler Connection, Richmond W. Smith Jr.

Henry Ford Hospital Medical Journal

No abstract provided.

Editorial: In Defense Of Historians, Conrad R. Lam

Henry Ford Hospital Medical Journal

No abstract provided.

Unprovoked Seizures And Myoclonus In Patients With Alzheimer's Disease, Marcia L. Morris

Journal of the Minnesota Academy of Science

Although anecdotal references commonly presume that seizures eventually occur in patients affected with dementia of the Alzheimer type (DAT), no previous American study has documented the rate of new onset, unprovoked seizures in DAT patients. There are few documented cases of the occurrence of myoclonus in autopsy-proven DAT. In a series of 83 autopsy-proven DAT cases, medical records were scrutinized for the presence of any seizure or myoclonic activity. Final evaluations were made by a neurologist. Of the 83 cases, 8 had experienced one or more unprovoked seizures after the onset of DAT. Based on age-specific incidence rates from a …

Triage: Endgame Realities, George P. Smith Ii

Scholarly Articles

No abstract provided.

The Role Of The Insulin Receptor In Skeletal Muscle Insulin Resistance: Evaluation Of Two Animal Models, Charles F. Burant

MUSC Theses and Dissertations

The role of the insulin receptor in muscle insulin resistance was studied. Denervation of skeletal muscle resulted in the rapid appearance of a decrease in basal and insulin stimulated glucose transport, glycogen synthesis and a defect in the activation of glycogen synthase which was independent of levels of glycogen in the muscle. The effect was seen in both predominantly red and predominantly white muscle. There was no change in the denervated muscles' sensitivity to epinephrine-mediated decrease in glycogen synthesis or glycogen content, nor was there a major change in the insulin binding capacity of denervated muscles. A technique was developed …

Vital Signs, Winter 1985, Boonshoft School Of Medicine

Vital Signs

A twenty seven page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, alumni profiles, class notes, and more.

Oncolog, Volume 30, Number 01, January-March 1985, Jordan U. Gutterman Md, Edwin C. Murphy, Jr. Md

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• Investigators Explore Role of Oncogenes in Normal Growth and Carcinogenesis
• Lung Cancer Surpasses Breast Cancer as Mortality Risk to Texas Women
• New NCI Data Base Offers Physicians Up-to-Date Cancer Treatment Information

Oncolog, Volume 30, Number 03, July-September 1985, Fernando F. Cabanillas Md

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• Natural Killer Cells: Research Shows They Are Early Destroyers of Malignancy
• Better Classification and New Drug Regimens Have Advanced Treatment for Lymphoid Cancer
• Rural Science Park is Laboratory for Basic Work on Carcinogenesis
• New Book: Candidiasis