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Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.

New Mexico Location List Of Alumni And Former Housestaff, Unm Medical School Alumni Office

University of New Mexico School of Medicine Location Report

No abstract provided.

An Overview Of The Newer Antibiotics, Ramon Del Busto

Henry Ford Hospital Medical Journal

The introduction of a large number of new antibiotics has made selecting the one most appropriate for treatment a confusing task for the practicing physician. One problem is that the differences in pharmacokinetics, in vitro activity, and clinical indications between some of these agents may be relatively minor; this is especially true of the new cephalosporins. Another problem is that the generic names of the cephalosporins are so similar that it is impractical, even for the infectious diseases specialist, to be familiar with all of them. This review attempts to summarize the most important characteristics of these new antibiotics and …

Viral Hepatitis: Update On Prevention, Miriam J. Alter

Henry Ford Hospital Medical Journal

No abstract provided.

Front Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Infectious Diseases And The Persisting Microbial Challenge, Louis D. Saravolatz

Henry Ford Hospital Medical Journal

No abstract provided.

Prospects For The Medical Use Of Interferon In 1984, Bosko Postic, Julio C. Arroyo

Henry Ford Hospital Medical Journal

Interferon, a natural and wide spectrum antiviral polypeptide that was discovered in 1957, has been extensively described. In addition to its antiviral effect, interferon has been found to suppress tumor growth and modulate the immune response. Until 1980, interferon was primarily prepared for clinical trials in human leukocytes derived from the buffy coat of whole blood. A major breakthrough occurred in the late 1970s when human interferon was produced by DNA recombinant methods in such heterologous cells as bacteria (genetic engineering). Interferon is not commercially available in 1984, but it may, based on clinical trials in humans, become part of …

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Inhibition Of Growth Of Toxoplasma Gondii In Cultured Fibroblasts By Human Recombinant Gamma Interferon., E. R. Pfefferkorn, Paul M. Guyre

Dartmouth Scholarship

The growth of Toxoplasma gondii in cultured human fibroblasts was inhibited by recombinant human gamma interferon at concentrations of 8 to 16 U/ml. The interferon was titrated by observing a total inhibition of parasite plaque formation 7 days after infection. Inhibition of the growth of T. gondii in the early days after infection was measured by marked reductions in the incorporation of radioactive uracil, a precursor that can only be used by the parasites. This assay showed that when cells were pretreated with gamma interferon for 1 day and then infected, inhibition of T. gondii growth could be readily detected …

Polymicrobal Pneumonia In A Corticosteroid-Treated Patient With Chronic Obstructive Lung Disease, John R. Haapaniemi, John Popovich Jr.

Henry Ford Hospital Medical Journal

The immunosuppressive properties of corticosteroids are well established and cause a depression of pulmonary defense mechanisms. We report the case of a patient treated with short-term corticosteroids for an exacerbation of chronic obstructive lung disease who developed a multiple organism pneumonia.

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Oncolog, Volume 29, Number 04, October-December 1984, Guy R. Newell Md

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• Computer Program Simulates Cell Growth, Provides Data for Cytotoxic Drug Studies
• UT MDAH Code of Ethics Guides Personnel in Making Complex Decisions Concerning Patients
• Epidemiologist Relates Hodgkin's Disease, Testicular Cancer, and Multiple Sclerosis
• Leech Gland Extract Inhibits Metastasis Enhancement by Drugs or Radiation in Mice

Vital Signs, Fall 1983, Boonshoft School Of Medicine

Vital Signs

A twelve page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, alumni profiles, class notes, and more.

Recommendations For Care Of The Asymptomatic Patient, James D. Bridges, Thomas Killip, N. Kevin Krane, David B. Macdougall, Carlos F. Petrozzi, Michael E. Somand, Susan Steigerwalt

Henry Ford Hospital Medical Journal

We present a set of reasonable guidelines for the care of healthy, asymptomatic individuals based upon recommendations prepared by an Internal Medicine review committee of Henry Ford Hospital. There recommendations have four goals: to prevent disease, to detect disease in an asymptomatic and potentially curable state, to enhance the patient's quality of life, and to help physicians teach patients good health habits. Recommendations are made for infectious diseases, cancer, metabolic diseases, neurosensory conditions like visual and hearing loss, and general health habits. Some recommendations are at variance with those of well recognized authorities and should be viewed only as a …

Vital Signs, Spring 1983, Boonshoft School Of Medicine

Vital Signs

A twenty five page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, alumni profiles, class notes, and more.

The Role Of Splenectomy In Endocarditis, Donald J. Magilligan Jr., Edward L. Quinn

Henry Ford Hospital Medical Journal

Five patients with endocarditis, persistent sepsis, and positive liver-spleen scans underwent splenectomy. Three had splenectomy performed concomitantly with cardiac valve replacement, one after valve replacement and one as an isolated procedure. Four of five spleens contained abscesses, and bacterial cultures of two were positive. Histologic study of one spleen revealed splenitis. All patients improved after splenectomy, and all are well two to twenty months postoperatively. An aggressive approach to splenic abscess in endocarditis may lead to reduced mortality from bacterial endocarditis and infected prosthetic valves.

Vital Signs, Fall 1982, Boonshoft School Of Medicine

Vital Signs

A twelve page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, alumni profiles, class notes, and more.

Digest Of The Philadelphia College Of Osteopathic Medicine (Summer 1982), Philadelphia College Of Osteopathic Medicine

Digest

The Summer 1982 issue of the Digest of the Philadelphia College of Osteopathic Medicine includes the following articles:

• President's Page
• Commencement
• Commencement Families
• Honorary Degree Recipient
• Master of Science
• Pre/Post Commencement
• Commencement Dinner
• Awards
• Class of 1982
• Class of 1982 Internships
• $4 Million Capital Campaign Special Section
• Hospital Honors Graduating House Staff
• Volunteers Honored
• Osteopathic Discovery
• Faculty Notes
• News from the OMCP
• News from the Alumni Office
• Alumni News Briefs
• In Memoriam

Vital Signs, Summer 1982, Boonshoft School Of Medicine

Vital Signs

A six page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, alumni profiles, class notes, and more.

Vital Signs, Spring 1982, Boonshoft School Of Medicine

Vital Signs

A seven page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, alumni profiles, class notes, and more.

Zoonoses In Modern Medical Practice, Tom Madhavan

Henry Ford Hospital Medical Journal

Zoonoses are infections transmitted by animals to man. Of the more than 50 such infections that are clinically significant, several are discussed in the articles by McIntosh and Madhavan and by Meyer and Adar in this issue of the Journal (pp. 7-13). These include brucellosis, leptospirosis, relapsing fever, Colorado tick fever, toxoplasmosis, psittacosis, and echinococcosis. The McIntosh and Madhavan article reviews the experience at Henry Ford Hospital with 60 patients, while the article by Meyer and Adar reports on an unusual case of echinococcosis of the spine and retroperitoneum that occurred at Haim Sheba Medical Center in Israel.

Zoonoses At Henry Ford Hospital: Clinical, Epidemiologic, And Therapeutic Aspects, Nancy Mcintosh, Tom Madhavan

Henry Ford Hospital Medical Journal

Zoonoses are diseases of animals that can be transmitted to humans. We reviewed the experience with zoonotic illnesses treated at Henry Ford Hospital in the past ten years. Included in this report are cases of brucellosis, leptospirosis, relapsing fever, Colorado tick fever, toxoplasmosis, psittacosis, and pasteurellosis. This report describes the clinical and epidemiologic aspects of zoonoses in 60 patients in a large urban general hospital.

Immunological Approaches To The Diagnosis Of Systemic Candidiasis, Gene Elizabeth Burges

MUSC Theses and Dissertations

The increasing incidence of systemic candidiasis and the difficulties diagnosing the disease on the basis of clinical data and culture results have prompted investigation into immunological methods of diagnosis. Detection of anti-Candida antibodies has proved to be not sufficiently specific for diagnosis of systemic disease since antibodies are frequently found in the normal individual in whom the organism lives as a commensal and in superficially infected individuals. Our project resulted in the development of a new quantitative immunofluorescence assay for quantitation of anti-Candida antibodies which is able to differentiate quite well (p< 0.0005) between systemically infected patients and normals or superficially infected patients. We have also investigated the value of purified antigens and have shown that the use of cytoplasmic protein antigens rather than those containing cell wall polysaccharide confers greater specificity on a qualitative test for anti-Candida antibodies but that a carbohydrate-containing antigen is adequate for differentiating systemic disease when a quantitative test is used. Attempts to diagnose systemic candidiasis by detection of circulating antigen have met with varying degrees of success. We were unable to detect antigen by counter-immunoelectrophoresis, a quantitative immunofluorescence inhibition assay, or an ELISA inhibition assay in the sera of rabbits in whom a Candida endocarditis was induced or in the sera of systemically infected patients. One postulated reason for this failure is the presence of the antigen in the form of circulating immune complexes. We have, therefore, investigated the possibility of the existence of complexes containing Candida antigen and antibody in the sera of patients with systemic candidiasis. Using four screening tests, a statistically significant difference (p < 0.05) was found for immune complex levels in a group of patients and a group of normal individuals. Isolation and characterization of immune complex-containing fractions from five patients with candidiasis indicated the presence of anti-Candida antibodies and/or antigen in at least three of them. Therefore, these fungal immune complexes can be assumed to exist and may play a role in the difficulties in detecting circulating antigen and, furthermore, may be involved in the pathogenesis and progression of disseminated candidiasis.

The Protective Role Of Superoxide Dismutase Against The Beta Cell Toxicity Of Diabetogenic Drugs, Samuel Evans Gandy Iii

MUSC Theses and Dissertations

Superoxide dismutase (SOD) is a scavenger of the toxic superoxide radical and thereby protects the integrity of cell components from oxidative damage. This enzyme is an essential part of the biological defense system of aerobic cells, both directly by removing the superoxide anion and indirectly by preventing the formation of hydroxyl radical when superoxide reacts with hydrogen peroxide. The chemical diabetogenic agent streptozotocin, alloxan and Vacor are reported to directly inhibit the activity of this enzyme. The role of SOD in protection of pancreatic beta cells from the toxicity of diabetogenic drugs and the interaction of the drug with enzyme …

Vaginal Colonization With Staphylococcus Aureus In Healthy Women: A Review Of Four Studies, Mary Guinan, Bruce B. Dan, Richard J. Guidotti, Arthur L. Reingold, George P. Schmid, Elena J. Bettoli, Joseph G. Lossick, Kathryn N. Shands, Mark A. Kramer, Nancy T. Hargrett, Roger L. Anderson, Claire V. Broome

School of Public Health Faculty Research

Four studies assessed the frequency of vaginal Staphylococcus aureus colonization in healthy women and associated risk factors. An association was found between S. aureus vaginal colonization and colonization at the labia minora and the anterior nares. Significant risk factors associated with an increased risk of vaginal S. aureus in at least one study were a history of genital herpes simplex infection, insertion of tampons without an applicator, and the use of Rely (Procter & Gamble) tampons. The use of systemic antibiotics within 2 weeks of the vaginal culture decreased the risk of recovery of S. aureus. The overall frequency …

Namru-3 Translations Of Parasite Literature From Russian, French, Japanese, Etc. Into English (1931-1982) T1501-T1600, United States Naval Medical Research Unit Number Three, Cairo, Medical Zoology Department

United States Naval Medical Research Unit 3: Publications

T1501. TRANSLATION FROM RUSSIAN. LEONOV, Yu. A. and KHARITONOVA, N. N. (1972). Experimental confirmation of the role of root voles in epizootiology of Omsk hemorrhagic fever. In: Transcontinental associations of migratory birds and their role in distribution of arboviruses, edited by Cherepanov, A. I. Mater. 5. Simp. Izuch. Roli Pereletn. Ptits Rasp. Arbovirus. (Novosibirsk, July 1969), pp. 355-358.

T1503. TRANSLATION FROM RUSSIAN. GASANOV, A. A. (1963). The infection of Rhipicephalus bursa (Can. et Fanz., 1877) with Babesia ovis in the Nakhichevan Region of the ASSR. Izv. Akad. Nauk Azerb. SSR, s. Biol. Med. Nauk, (4):117-123.

T1504. TRANSLATION FROM RUSSIAN. TSAPRUN, …

Vital Signs, November 1981, Boonshoft School Of Medicine

Vital Signs

A twelve page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, alumni profiles, class notes, and more.

The Role Of Industry In The Development Of Biomedical Technology, Raymond H. Kahn

Henry Ford Hospital Medical Journal

The world is undergoing a biological revolution that has made unparalleled demands on the American health care system. This demand for health care and its escalating costs provide abundant Incentives for reducing the cost through better technology. Recent developments in medical technology include the CAT scanner, nuclear magnetic resonance (NMR), as well as new advances in prosthetic devices. Most biomedical research and development takes place at not-for-profit institutions, such as universities, hospitals, and private foundations, much of it supported by federal funding from such sources as the National Institutes of Health. But, today, the institutions are in danger of major …

Digest Of The Philadelphia College Of Osteopathic Medicine (Summer 1981), Philadelphia College Of Osteopathic Medicine

Digest

The Summer 1981 issue of the Digest of the Philadelphia College of Osteopathic Medicine includes the following articles:

• President's Page
• Commencement
• Honorary Degree Recipient
• Master of Science
• Commencement Dinner
• Awards
• Class of 1981 Internships
• Class of 1981
• News from the Hospital
• News from the College
• Faculty Notes
• News from the Division of Special and Continuing Education
• New Appointments
• News from the Alumni Office
• Alumni News Briefs
• In Memoriam
• Founders Day Schedule

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.