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Aids Update, Evelyn J. Fisher

Henry Ford Hospital Medical Journal

No abstract provided.

Primary Neurologic Complications Of The Acquired Immunodeficiency Syndrome, Stuart N. Kieran

Henry Ford Hospital Medical Journal

No abstract provided.

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Dexamethasone And The Serious Head Injury, Rashid Jooma

Section of Neurosurgery

No abstract provided.

The Effects Of Alpha Adrenergic Blockade On Arachidonic Acid Metabolism And Shock Sequelae During Septic Shock In The Rat, Jeffrey Armstrong

MUSC Theses and Dissertations

Increased activity of the alpha adrenergic nervous system may be a significant factor promoting tissue ischemia in endotoxic shock. The suggestion that increased sympathetic activity affects prostaglandin synthesis prompted investigation of the potential interaction between the adrenergic nervous system and arachidonic acid metabolites during endotoxemia and septicemia. In addition, the possibility that the underlying patterns of arachidonic acid metabolites seen in two different shock models may provide a rationale for therapeutic intervention designed to block either or both the synthesis of arachidonic acid metabolites or the activity of the adrenergic nervous system was examined. Studies were undertaken to determine the …

Oncolog, Volume 32, Number 02, April-June 1987, Lillian M. Fuller Md, Gabriel Lopez-Berestein

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• Limited Chemotherapy and Radiotherapy Effective in Stage I and II Hodgkin's Disease in Adults
• Gene Rearrangement May Affect Prognosis of Some Chronic Myelogenous Leukemia Patients
• Liposomal Antibiotic Better, Less Toxic Than Free Drug for Treating Fungal Infections

Oncolog, Volume 32, Number 04, October-December 1987, Cheryl Mokrzecky

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• Patients with Highly Invasive Cutaneous Melanoma Need Selective, Focused Evaluations Before Surgery\
• Diagnostic Radiologists Use Expandable Metallic Stents for Symptom Relief in Selected Patients
• Nutritional and Psychological Aspects of Feeding Children Who Have Cancer
• Adjuvant Chemotherapy Improves Survival of Patients with Stage II and III Breast Cancer

Oncolog, Volume 32, Number 03, October - December 1987, Douglas E. Johnson Md

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• Improved Survival Results from Early Detection and Diagnosis of Testicular Cancer
• Current Laboratory Research Modernizes Traditional Chinese Herbal Medicine
• Gastrointestinal Radiotherapy Team Creates Atmosphere of Comfort and Confidence for Patients

Digest Of The Philadelphia College Of Osteopathic Medicine (Fall 1986), Philadelphia College Of Osteopathic Medicine

Digest

The Fall 1986 issue of the Digest of the Philadelphia College of Osteopathic Medicine includes the following articles:

• Making Them Comfortable
• John J. Fernandes, DO
• Pathology Department to be Computerized
• O.J. Snyder Award Recipient
• In the Land of Shoo-fly Pie
• Class Acts
• In Memorium
• How Sweet It Is
• On Campus
• Calendar

Vital Signs, Fall 1986, Boonshoft School Of Medicine

Vital Signs

A thirty four page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, alumni profiles, class notes, and more.

Beta-Adrenergic Blocking Agents In Congestive Heart Failure, Sidney Goldstein

Henry Ford Hospital Medical Journal

Although recent physiologic studies suggest that increased catecholamine release in humans may in the long run represent an adverse homeostatic mechanism, this catecholamine release is acutely important in permitting human response to stress. Clinical interventions with beta-adrenergic blocking agents have showed a salutary effect on cardiac function in patients with severe heart failure: in patients with heart failure associated with myocardial infarction, these agents may help improve mortality rates. These studies indicate that the drugs are well tolerated when used carefully in these high-risk patients.

New Positive Inotropic Agents, Syed M. Jafri, James A. Bristol

Henry Ford Hospital Medical Journal

Current therapy for heart failure remains inadequate. New positive inotropic agents that augment myocardial contractility have been introduced. The positive inotropic effects of these nonglycoside, nonsympathomimetic agents are due, at least in part, to inhibition of cardiac phosphodiesterase activity and hence to an increase in myocardial cyclic AMP levels. These agents also have vasodilator properties through their effects on the enzyme phosphodiesterase in the vascular smooth muscle. Recent developments in the preclinical pharmacology, mechanism of action, and clinical experience with these new inotrope vasodilators are presented in this review. The role these drugs will play in revising our therapeutic strategy …

Status Of Cardiac Transplantation With A Report Of The First Year's Experience At Henry Ford Hospital, Fraser M. Keith, Donald J. Magilligan Jr., Jeffrey B. Lakier, Conrad Drost

Henry Ford Hospital Medical Journal

Cardiac transplantation is now widely accepted as effective treatment for selected patients with end-stage heart disease. Improvements in immunosuppressive treatment and monitoring in the past 15 years have resulted in impressive one-year and five-year survival rates of 80% and 60%. In general, survivors have enjoyed a considerably improved quality of life. A cardiac transplantation program was initiated at Henry Ford Hospital in 1985, and a total of 15 patients received heart transplants in the first 12 months. Fourteen patients are currently alive and well at various stages posttransplant. This early clinical success has prompted the consideration of both combined heart-lung …

Sprague-Dawley Rats Fed Milk Or Beef Protein : Differences In Response To 1,2-Dimethylhydrazine Carcinogenesis, Stanley W. L. Ng

Loma Linda University Electronic Theses, Dissertations & Projects

Colon cancer is responsible for a high percentage of cancer deaths in developing countries, and there is convincing epidemiological evidence that meat protein and fat in the diet increase the incidence of this form of cancer. An animal tumor model which has been used by many investigators interested in colon cancer is the 1,2-dimethylhydrazine (DMH)-rat or DMH-mouse tumor model. In previous work done in this laboratory the DMH-BALB/c mouse tumor model was used to compare the production of colon tumors in mice fed a diet using non-fat powdered milk as a source of protein with those in mice fed beef …

The Safety And Efficacy Of A New Patient-Controlled Analgesia Device In Hospitalized Trauma And Surgery Patients, Terry J. Baumann, Luz Maria Gutschi, Brack A. Bivins

Henry Ford Hospital Medical Journal

The objective of this investigation was to evaluate a new patient-controlled analgesia (PCA) device. Eighteen trauma and surgical patients were allowed to use a self-activated, intravenous infusion device for two to seven days for postoperative pain relief. Initial PCA dosage/interval settings were adjusted to provide a 0.5 to 1 mg dosage of morphine per injection with a six-minute lockout interval. Adjustments were made to these initial settings based on the individual patient's response. Pain and sedation scores and respiratory rates were recorded. Subjective evaluations of PCA indicated that 17 of the 18 patients (94.4%) participating in the study "preferred this …

Pulmonary Microembolism In The Canine Model: Report Of A Pilot Study, Brack A. Bivins, Robert P. Rapp, Richard M. Bell

Henry Ford Hospital Medical Journal

Use of in-line final filters to prevent the infusion of foreign particulates has lowered the rates of postinfusion phlebitis in several controlled studies. The systemic effect of particulate infusion, however, has not been thoroughly studied. In this study, 12 mongrel dogs recovering from a right pneumonectomy were studied following infusion of various-sized particulates. Ten of the dogs were infused with either 10 or 40 million, 9 or 25 μm, latex particles. The remaining two dogs were control animals. Hemodynamic parameters were monitored in each animal. At death or 72 hours following particle injection, the left lung was examined grossly and …

Medical Challenges In Space, Boy Frame

Henry Ford Hospital Medical Journal

No abstract provided.

Correlates Of Birth Weight And Gestation Age : Baseline Data For Health Education, Adanetch Kidanemariam

Loma Linda University Electronic Theses, Dissertations & Projects

Purpose. The study examined the correlation of maternal occupation, urinary tract infection, smoking, and working during pregnancy with infant birth weight and gestational age in order to generate baseline data for development of a health education intervention program protocol for pregnant women In the work place.

Primary Hypotheses. (1) The four maternal risk factors: (a) occupation during lifetime, (b) reported urinary tract infection, (c) cigarette smoking, (d) working, are individually and interactively correlated with infant birth weight and gestational age. (2) The effects of the interactive associations are greater on birth weight than gestational age.

Procedure. A sample of …

Magnesium, Copper And Zinc Concentrations In Blood From Children With Diabetes Mellitus, Linda Lowers Jenkins

Chemistry & Biochemistry Theses & Dissertations

Trace element levels in blood from diabetic children were investigated and compared to control children. Plasma, erythrocyte, mononuclear and polymorphonuclear cells were analyzed for magnesium, copper, and zinc content. Leukocyte separation was performed by density gradient centrifugation on Ficoll-Hypaque, followed by washing steps to remove platelet contamination and hypotonic lysis to remove red cell contamination. Polarized Zeeman-effect atomic absorption spectroscopy was used for trace metal analysis.

Decreased plasma magnesium levels were observed in the diabetic children. This finding is well documented and probably due to increased urinary magnesium loss from glycosuria. Lymphocyte magnesium levels in the diabetic children were also …

The Phenomenon Of Multiple Stretch Reflexes, Robert D. Teasdall

Henry Ford Hospital Medical Journal

Multiple stretch reflexes occur in muscles adjacent to or remote from the tap. The response may be ipsilateral or bilateral. These reflexes are encountered not only in normal subjects with brisk stretch reflexes but particularly in patients with lesions of the upper motor neuron. The concussion obtained by the blow is conducted along bone to muscle. Muscle spindles are stimulated, and in this manner independent stretch reflexes are produced in these muscles. This mechanism is responsible for the phenomenon of multiple stretch reflexes. The thorax and pelvis play important roles in the contralateral responses by transmitting these mechanical events across …

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Interventional Neuroradiology: Henry Ford Hospital Experience With Transcatheter Embolization Of Vascular Lesions In The Head, Neck, And Spine, Bharat A. Mehta, Clifford R. Jack Jr., Roushdy S. Boulos, Suresh C. Patel, James I. Ausman, Ghaus M. Malik

Henry Ford Hospital Medical Journal

Innovative developments over the past 15 years have resulted in increased sophistication and effectiveness of therapeutic neuroembolization procedures. As a result, percutaneous transcatheter embolization has assumed an increasingly important role in the management of patients with vascular lesions of the head, neck, and spine. By reducing bleeding during surgery, this technique can markedly facilitate the surgical approach to difficult vascular lesions. The technique may also be applied in cases where surgery is contraindicated. Therapeutic neuroembolization has been performed in 23 patients with vascular lesions of the head, neck, or spine at Henry Ford Hospital. Devascularization of the extraaxial blood supply …

Psychocardiologic Perspectives Of Coronary Artery Disease, Richard Ketai

Henry Ford Hospital Medical Journal

The importance of mind, emotion, and behavior as they relate to the heart, particularly coronary artery disease, is growing in recognition. A review of the research shows increasingly sophisticated demonstrations of links unifying heart function and mind. "Psychocardiology" would be an appropriate term for the diverse areas of interest which focus on the psychosocial correlates of heart disease. This paper illustrates this concept through a review of psychosocial and behavioral aspects of coronary artery disease.

Low Toxicity Radiation Sensitizer, Barton L. Bergquist, James C. Chang

Patents (University of Northern Iowa)

This invention relates to cisplatin type fluorescently labeled compounds. In particular, the compounds are bis (5-aminofluorescein)-dichloroplatinum (II) or certain substituted analogues thereof. The compounds are useful as radiation sensitivity enhancers and as fluorescent biological tracers. The invention also relates to a unique, single step synthesis for preparing said compounds.

The Effect Of Intraperitoneally Administered Thyroxine, Thiidothyronine And Iopanoic Acid On The In Vivo And In Vitro Oxygen Consumption Rates Of Normal (C57bl/Ksj Db/M) And Diabetic (C57bl/Ksj Db/Db) Mice, A. Kay. Kalousek

Theses Digitization Project

No abstract provided.

Pregnancy Diagnosis Using Ultrasound, M A C Johns

Journal of the Department of Agriculture, Western Australia, Series 4

Few Western Australian ewe flocks are diagnosed for pregnancy despite the precence of high numbers of barren ewes. Surveys of farm flocks in the early 1970s recorded that between 14 and 29 per cent of ewes failed to lamb each year.

Techniques for diagnosing pregnant ewes have been available for many years, but ultrasonic devices and computer technology have made it possible for skilled operators to determine whether ewes are pregnant and more importantly, whether they have one, two or more foetuses.

Once the number of pregnant ewes is known farmers can use labour more efficiently. They can minimise the …

Vital Signs, Winter 1986, Boonshoft School Of Medicine

Vital Signs

A twenty eight page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, alumni profiles, class notes, and more.

Oncolog, Volume 31, Number 03, July-September 1986, Staff

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• Learning How and Why Drugs Kill Cells Is Chemotherapy Researchers' Prime Goal
• Cancer Prevention Begins at Home: With MDA Screening and Detection Clinic
• Grant Taylor Organized First Collaborative Drug Research Group in This Part of the Country

Oncolog, Volume 31, Number 01, January-March 1986, Lester J. Peters Md

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• From Ability to Measure Cell Survival Come New Radiotherapeutic Strategies
• Diagnosing the Rare Lesion: Ovarian and Omental Ependymomas
• Radiotherapy Tailored to Patient's Disease

Clinical Trials: Ii. Randomization And Sample Size, Barbara Tilley, Anthony Schork

Henry Ford Hospital Medical Journal

This second in a series of articles focuses on clinical trials. Information is provided on determining sample size and on methods of randomization including simple and single- and double-consent randomization, and blocked, stratified, and adaptive procedures to randomize patients to a study group.