Digital Commons Network^™

A Rare Cause Of Upper Gastrointestinal System Bleeding: Pancreatic Endocrine Neoplasm, Oral Saygun, Fati̇h Mehmet Avşar, İ. Hakan Özel, Süleyman Hengi̇rmen, Levent Albayrak, Sema Hücümenoğlu

Turkish Journal of Medical Sciences

No abstract provided.

Lateral Periodontal Cyst, Işil Saygun, Ati̇lla Özdemi̇r, Mükerrem Safali

Turkish Journal of Medical Sciences

No abstract provided.

Effects Of Paf Antagonist Bn52021 On Systemic And Renal Oxidative Stress In Experimentally Induced Obstructive Jaundice, Nusret Akyürek, Mustafa Kerek, Erdoğan M. Sözüer, Murat Alper, Sabahatti̇n Muhtaroğlu, Mustafa Keçeli̇

Turkish Journal of Medical Sciences

The aim of this study is to investigate the effects of PAF antagonist BN52021 on systemic and renal oxidative stress in experimentally induced obstructive jaundice. A total of 30 Wistar-Albino type rats used in the study were divided into sham, control and study groups, each consisting of ten subjects. A laparotomy was performed on the study and control groups, and the choledochus was ligated and dissected. In the sham group, the choledochus was dissected by laparotomy and not ligated. The subjects in the control group were administered physiological saline intraperiotoneally between the 2^{nd} and 7^{th} days, and subjects in the …

The Effects Of Different Suture Techniques On Wound Healing In Abdominal Wall Closure, Mustafa Şahi̇n, Mehmet Karademi̇r, Şükrü Özer, Fati̇h Mehmet Avşar, Serdar Yol, Osman Çağlayan, Murat Aktan

Turkish Journal of Medical Sciences

Purpose: The aim this study was to investigate the effects of different suture techniques on the healing of abdominal wall wound. Materials and Methods: 24 male Wistar albino rats were included in this study. The rats were divided into two groups. A 4 cm midline laparatomy was performed after ketamine HCl anesthesia. In Group I, the incision was sutured with 4/0 polypropylene interruptedly and in Group II, the wound was closed with 4/0 polypropylene continuously. The skin was sutured with an interrupted 4/0 silk suture. Then 2 cc of blood was withdrawn for biochemical and hematological tests by cardiac puncture. …

Comparative Histological Analysis Of Hepatitis C Virus With Hepatitis B, Gülen Akyol, Özlem Süer, Cem Sezer

Turkish Journal of Medical Sciences

Aims: Rates of certain histopathologic features were evaluated in hepatitis C and in hepatitis B materials and analyzed statistically in a Turkish population. Method: The presence of lymphoid aggregate, steatosis, ductal lesions, sinusoidal inflammation and portal iron deposition were investigated in 80 hepatitis C and 104 hepatitis B specimens and evaluated using the chi-square test and Fisher's exact test. Pan Band T cell markers were used for lymphoid aggregate analysis. P53 and PCNA were applied for the possible impact of steatosis on cell biology. Results: All mentioned parameters excluding sinusoidal inflammation were found to be higher in hepatitis C samples. …

Allele Frequencıes Of The Humf13b Str Locus In The Çukurova Region, Lale Dönbak, Serpi̇l Salaçi̇n

Turkish Journal of Medical Sciences

In this study, the STR system HumF13B polymorphism and forensic efficiency values were investigated in a population sample from the Çukurova region. The F13B phenotypes were analysed using polyacrylamide gel electrophoresis (PAGE) following a polymerase chain reaction (PCR) and were visualised by silver staining. Allele frequencies were calculated by the gene counting method. Forensic efficiency values were estimated using the obtained gene frequencies of F13B. In this population sample, a total of five alleles, 6, 7, 8, 9 and 10 of F13B, were observed. The calculated frequencies of these alleles were as follows: 6=0.0910; 7=0.0045; 8=0.3273; 9=0.2045; 10=0.3727. In the …

Medicolegal Aspects Of Blood-Urine Toluene And Urinary Ortho-Cresol Concentrations In Toluene Exposure, Serap A. Akgür, Pembe Öztürk, Yusuf Kurtulmuş, Hüseyi̇n Karali̇, Süheyla Ertürk

Turkish Journal of Medical Sciences

Toluene is a widely used solvent in different industrial areas and has a depressant effect on the central nervous system. In medicolegal cases, for the possible influence of toluene on actions or conditions prior to death, a reliable indicator of exposure must be precisely investigated. We developed an appropriate method for toluene analysis and investigate the blood-urine toluene levels and urinary ortho-cresol levels in toluene-exposed workers. Blood and urine toluene levels from 50 male subjects were detected by Gas Chromatography-FID (GC-FID) using the head-space method, and urinary o-cresol levels, a metabolite of toluene, were analyzed by GC. The significance of …

Large Loop Excision Of The Transformation Zone: An Outpatient Procedure, Mehmet Rafet Gazvani, Özkan Öztürk

Turkish Journal of Medical Sciences

A prospective, observational study was carried out to assess the efficacy of Large Loop Excision of the Transformation Zone (LLETZ) as an outpatient procedure during the first visit of patients with abnormal cervical smears. One hundred and seven women were treated with LLETZ under local anaesthesia as an outpatient procedure at their first visit. All patients were followed up routinely with colposcopy, cytology, and also histology where appropriate for at least 6 months. In all cases, the specimens obtained were adequate for histopathological assessment, and in 103 cases (96%), the lesion had been completely excised. When compared, the degree of …

Serum Triglyceride And Lipoprotein-Cholesterol Levels In Patients With And Without Luteal Phase Defect, Hi̇kmet Hassa, Ömer T. Yalçin, Atti̇la Yildirim, H. Mete Tanir, Özgül Paşaoğlu, Mi̇ne İnan

Turkish Journal of Medical Sciences

Objective: To evaluate the serum triglyceride and lipoprotein-cholesterol levels in subjects with and without luteal phase defect. Method: Early follicular and midluteal phase serum triglycerides, lipoprotein-cholesterol and progesterone levels were assessed in 19 subjects with and in 73 subjects without luteal phase defect. The criterion for diagnosis of luteal phase defect was histological development of endometrium delayed for more than 2 days according to the chronological day. The data were analyzed by paired and unpaired t tests, Chi-square test and correlation analysis. Results: The early follicular serum triglyceride and lipoprotein-cholesterol levels of the two groups were similar (p>0.05). The …

Frequency Of Use Of The Various Classes Of Removable Partial Dentures And Selection Of Major Connectors And Direct / Indirect Retainers, Fi̇li̇z Keyf

Turkish Journal of Medical Sciences

Selecting the individually suitable form of and location for the major connectors in partially edentulous patients is important. The purpose of classifying removable partial dentures (RPDs) is to simplify identification. Classification also allows for a longitudinal comparison of various classes of RPDs as well as the determination of whether the teaching of RPD design is consistent with the relative frequencies of RPD use. This study surveyed the various types of RPDs being fabricated in a dental laboratory and compared those findings with the data from a previous study. Results indicated that mandibular RPDs are more common than maxillary RPDs, and …

Paget's Disease Of The Male Breast - A Case Report, Sema Hücümenoğlu, Handan Kaya, Fati̇h Mehmet Avşar

Turkish Journal of Medical Sciences

ÜMENOĞLU^1 Handan KAYA^2 Fatih Mehmet AVŞAR^3 ^1Department of Pathology, SSK Ankara Training and Research Hospital, Ankara, ^2Department of Pathology, Faculty of Medicine, Marmara University, Istanbul, ^3Department of 1st Surgery, Ankara Numune Training and Research Hospital, Ankara - TURKEY

A Case Of Bisatellited-Isodicentric Supernumerary Chromosome 15, Y. Selma Süngü, Bi̇rsen Karaman, E. Ferda Perçi̇n, Sevi̇m Balci, İlhan Sezgi̇n

Turkish Journal of Medical Sciences

SÜNGÜ^1 Birsen KARAMAN^2 E. Ferda PERÇİN^1 Sevim BALCI^3 İlhan SEZGİN^1 ^1Department of Medical Biology and Genetics, Faculty of Medicine, Cumhuriyet University 58140-Sivas, ^2Department of Medical Genetics, Faculty of Medicine, Istanbul University, Çapa -Istanbul, ^3Department of Pediatrics, Faculty of Medicine, Hacettepe University Ankara - TURKEY

Colicin Production And Colicin Typing Of Uropathogenic Escherichia Coli, Ayli̇n İmren Çarikçi, Güner Coşar

Turkish Journal of Medical Sciences

Colicins are bactericidal macromolecules in protein structures and they are produced by some strains of Escherichia coli and Shigella, which are members of the Enterobacteriaceae. They have a bactericidal effect on the same species or closely related bacteria, but have no effect on the strains which produce them. In this study, 129 E. coli strains isolated from urine samples of patients in Izmir and Manisa were examined for colicin production, and the colicinogenic strains were examined for their colicin types by means of Horak specific indicator strains. Indicator strains were obtained from the National Type Culture Collection Hygiene and Epidemiology …

Antifungal Activities Of Different Extracts And Echimidine-N-Oxide From Symphytum Sylvaticum Boiss. Subsp. Sepulcrale (Boiss. & Bal.) Greuter & Burdet Var. Sepulcrale, Murat Kartal, Semra Kurucu, Muhammad I. Choudary

Turkish Journal of Medical Sciences

Antifungal activity was determined by the tube dilution method on different extracts of Symphytum sylvaticum Boiss. subsp. sepulcrale (Boiss. & Bal.) Greuter & Burdet var. sepulcrale. The antifungal activity of the isolated compound from the root alkaloid fraction (Echimidine-N-Oxide) was also tested against ten fungal cultures. The activity was found to be mainly due to Echimidine-N-Oxide (ENO). The quantitative determination of ENO was also carried out with capillary gas chromatography in the roots and the aerial parts of the plant.

Human Herpesvirus 8 (Hhv-8) In Non-Hiv Associated Forms Of Kaposi's Sarcoma From Turkey, Ni̇lgün Şentürk, Sedef Şahi̇n, Serpi̇l Erci̇ş, Tanil Kocagöz, Ni̇lgün Atakan

Turkish Journal of Medical Sciences

Objective: Kaposi's sarcoma (KS), first described in 1872 by Moritz Kaposi, is a spindle cell, multifocal vascular tumor. Despite the intense work on the pathogenesis of KS, its etiology remains in doubt. The aim of this study was to determine the presence of HHV-8 sequences in non-HIV associated Kaposi's sarcoma patients, namely classical and immunosuppression-associated, and compare the results with normal healthy subjects. Materials and Methods: Nineteen patients with classical Kaposi's sarcoma (CKS), and nine patients with immunosuppression-associated Kaposi's sarcoma (ISKS) (6 renal transplantation, 1 Behçet's disease, 1 high grade lymphoma, 1 ataxia telangiectasia) were included in this study. Skin …

Detection Of Human Papilloma Virus In Benign, Malignant And Pre-Cancerous Lesions Of Oral Mucosa By In Situ Hybridization, Mehmet Yaltirik, Ayla Özveren, Canan Alatli, Nevi̇n Büyükakyüz

Turkish Journal of Medical Sciences

HPV is an epitheliotropic virus, predominantly associated with human skin and mucosal lesions. In many studies, the presence of HPV types 6/11, 16/18 and 31/33/51 have been demonstrated in oral lesions. The aim of this study is to investigate the presence of specific types of HPV in oral benign and precancerous epithelial lesions and oral carcinomas, and the etiological significance of HPV in oral epithelial malignancies. In the present study, twenty oral lesions, of which seven were papilloma, seven squamous cell carcinoma, four leukoplakia and two lichen planus, were tested for different types of HPV. In addition, these patients were …

Expression Of Fas Antigen And Bcl-2 Protein In Liver Tissues Of Patients With Chronic Hepatitis B, Ayşe Polat, Fazi̇let Kayaselçuk, Reyhan Eği̇lmez, İlhan Tuncer

Turkish Journal of Medical Sciences

The aim of this study was to evaluate the role of apoptosis in chronic hepatitis B, and correlate it with disease severity. We studied the expression of the Fas antigen (FasAg) and Bcl-2 protein in a group of patients with chronic hepatitis B at various stages of the disease. Four liver biopsy specimens taken from the patients with chronic hepatitis B infection and five control liver tissue specimens with normal histology were studied. Liver specimens were scored for disease severity according to Knodell's hepatic activity index (HAI). The percentage of hepatic expression was evaluated semi-quantitively. Our immunohistochemical study showed that …

Effects Of Oral L-Glutamine, Insulin And Laxative On The Severity Of Acute Pancreatitis, Fati̇h Mehmet Avşar, Mustafa Şahi̇n, Oral Saygun, İ. Hakan Özel, Süleyman Hengi̇rmen, Hüsametti̇n Vatansev, Ertuğrul Kafali, Osman Yilmaz

Turkish Journal of Medical Sciences

Aim: To investigate the effects of oral L-glutamine, insulin and laxative on the severity of acute pancreatitis. Materials and Methods: Forty adult male Sprague-Dawley rats were divided into 4 groups. Experimental pancreatitis was induced by ligating the main biliopancreatic duct. All groups were given standard rat pellets and tap water. In addition Group II was given 15 mg/kg/day of L-glutamine via a catheter enterally, Group III was given a 3 ml/day fleet enema via a catheter enterally, and Group IV was given 3 IU/kg/day of NPH insulin via a catheter enterally. The rats were sacrificed 96 hours after the induction …

Comparison Of Remifentanil-Propofol And Sevoflurane For Preventing Cardiovascular Response And Quality Of Recovery In Paediatric Otolaryngologic Surgery, Zeli̇ha Özer Koçak, Ali̇ Aydin Altunkan, Şebnem Atici, İsmai̇l Ci̇nel, Uğur Oral

Turkish Journal of Medical Sciences

As the practice of outpatient paediatric surgery advances, the search continues for anaesthesia that provides rapid smooth induction, stable patient haemodynamics, rapid emergence and minimal unpleasant side effects. Therefore, this study was designed to compare the haemodynamic changes, emergence and recovery characteristics of remifentanil-propofol (TIVA) and sevoflurane anaesthesia for adenoidectomy with bilateral myringotomy and insertion of tubes and/or tonsillectomy (ENT surgery) in children. Children aged 6.3±1.6 years, undergoing elective ENT surgery, were randomly assigned to receive TIVA (n=15) and sevoflurane (n=15). In both groups, anaesthesia was induced with propofol and remifentanil and maintained either with infusion of propofol-remifentanil or sevoflurane …

Sublingual Valsartan In Hypertensıve Urgency, Yüksel Gökel, Sai̇me Paydaş, Güven Kuvandik, Nazan Alparslan

Turkish Journal of Medical Sciences

The objective of this study was to assess the effect of sublingual valsartan in a group of patients with hypertensive urgency. Forty-one patients with hypertensive urgency and systolic blood pressure >200 mmHg, diastolic blood pressure >100 mmHg were studied in an emergency room. Supine blood pressure readings were taken and the patients were given 80 mg of valsartan sublingually. Blood pressure and heart rate were recorded at 15 min intervals over a 90 min period. Systolic blood pressure decreased from 211.22±14.65 mmHg to 158.17±15.48 mmHg, diastolic blood pressure dropped from 120.12±13.44 mmHg to 93.05±6.01 mmHg. The differences were statistically significant. …

Reconstruction Of Temporomandibular Joint Using Distraction Osteogenesis, Reha Ş. Ki̇şni̇şçi̇, Doğan Dolanmaz, Hakan H. Tüz

Turkish Journal of Medical Sciences

KİŞNİŞCİ^1 Doğan DOLANMAZ^2 Hakan H. TÜZ^1 ^1Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Ankara University, Ankara ^2Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Selçuk University, Konya-TURKEY

Adenomyoma Of The Stomach Accompanying Gastric Adenocarcinoma, Sema Hücümenoğlu, Musa Zorlu, Hakan Güzel, Fati̇h Mehmet Avşar

Turkish Journal of Medical Sciences

ÜMENOĞLU^1 Musa ZORLU^2 Hakan GÜZEL^2 Fatih Mehmet AVŞAR^3 Departments of ^1Pathology, ^2General Surgery, SSK Ankara Training and Research Hospital, ^3Department of General Surgery, Ankara Numune Training and Research Hospital, Ankara - TURKEY

Leptin And Mast Cells: A Novel Adipoimmune Link, Mariana Hristova, Luigi Aloe, Peter I. Ghenev, Marco Fiore, George N. Chaldakov

Turkish Journal of Medical Sciences

HRISTOVA^1 Luigi ALOE^2 Peter I. GHENEV^3 Marco FIORE^2 George N. CHALDAKOV^4 ^1Endocrinology Clinic, Medical University, Varna, Bulgaria, ^2Institute of Neurobiology, CNR, Rome, Italy, ^3Department of General and Clinical Pathology and ^4Division of Electron Microscopy, Department of Forensic Medicine, Medical University, Varna, Bulgaria

Biochemical Bone Markers In Prostate Cancer Patients With Local And Advanced Bone Metastates, Hülya Aksoy, Yilmaz Aksoy, Fati̇h Akçay, İsa Özbey

Turkish Journal of Medical Sciences

In the present study involving patients with bone metastases arising from prostate cancer, we measured urinary deoxypyridinoline (DPD) as a marker of collagen breakdown activity, serum total and bone-specific alkaline phosphatase activities and serum prostate specific antigen (PSA). This study included 20 patients with benign prostate hyperplasia (BPH) and 23 patients with carcinoma, 11 of had with bone metastases. DPD excretion in urine was significantly greater in prostate cancer patients with bone metastasis than in those with localised prostate cancer or BPH (p0.05). The serum markers of bone formation [total alkaline phosphatase (T-ALP) and bone ALP (B-ALP)] displayed higher mean …

Unusual Presentation Of A Chondromyxoid Fibroma Of The Temporal Bone, Asuman Ni̇han Haberal, Banu Bi̇lezi̇kçi̇, Mehmet Coşkun, Nur Altinörs, Beyhan Demi̇rhan

Turkish Journal of Medical Sciences

No abstract provided.

Diabetic Osteopathy: Who Is At Risk?, Serap Demi̇r, Ayşi̇n Öge, Selma Karaahmetoğlu, Osman Müftüoğlu, Seni̇ha Naldöken

Turkish Journal of Medical Sciences

This study was designed to determine the prevalence of osteopathy in diabetic patients, who are at risk of developing osteopathy, and clarify the relationship between osteopathy and other complications of diabetes mellitus. Thirty-four type I and 66 type II diabetic patients admitted to the endocrinology clinic between 1996 and 1997 and 30 nondiabetic subjects as a control group were studied. Bone scintigraphy (Tc 99m methylene diphosphonate) was used for the diagnosis of osteopathy. The body mass index (BMI) of each patient was calculated. Polyneuropathy was assessed by electromyography and the patients, for each of whom BMI was calculated, were asked …

The Hemodynamic Responses To Hypothermic And Normothermic Cardiopulmonary Bypass, Rahmi̇ Zeybek, Tayfun Adanir, İhsan İşkesen, Egemen Tüzün

Turkish Journal of Medical Sciences

This prospective randomized clinical study was designed to assess and compare the effects of normothermic and hypothermic nonpulsative cardiopulmonary bypass in patients with mitral valve replacement. Forty patients undergoing elective mitral valve replacement were randomly divided into two groups according to the temperature of perfusion. Group N (15 patients) underwent normothermic cardiopulmonary perfusion and Group H (25 patients) underwent hypothermic cardiopulmonary perfusion. These groups were compared using clinical and electrocardiographic criteria and cardiovascular evaluation parameters. Quantitative data were analyzed using the paired Student t test. While there was a significant increment in heart rate in Group N in relation to …

Effects Of Cigarette Smoking On Blood Antioxidant Status In Short-Term And Long-Term Smokers, Hüda Di̇ken, Mustafa Kelle, Cemi̇l Tümer, Basra Deni̇z, Yüksel Baylan, Abdurrahman Şermet

Turkish Journal of Medical Sciences

To determine the effects of cigarette smoking on blood antioxidant status and lipid peroxidation, 16 healthy male current smokers (CS) and 16 healthy male non-smokers (NS) serving as controls were studied. CS were divided into two groups: short-term smokers (STS) 35.4 ± 5.8 years of age (mean±SD), and long-term smokers (LTS) 60.9 ± 4.9 years of age. The average smoking period of STS and LTS were 8.1 ± 1.1 years (mean ±SD) and 20.5 ± 4.5 years (mean ± SD)respectively. STS and LTS had their own controls, who were NS (young NS and old NS respectively). When STS and LTS …

Effect Of Mg^{+2} Concentration In Mueller-Hinton Agar On The Susceptibility Of Pseudomonas Aeruginosa To Levofloxacin, Nezahat Akpolat, Tuncer Özeki̇nci̇, Selahatti̇n Atmaca

Turkish Journal of Medical Sciences

No abstract provided.

A Noninvasive Test For Vesico-Ureteric Reflux In Children, R. A. Mevorach, B. Cilento, S. Zahorian, C. Badgett, R. Walker, A. Atala, S. Iannello, M. Meyer

Electrical & Computer Engineering Faculty Publications

Objective To report the development and testing of a device for the noninvasive diagnosis of vesico‐ureteric reflux (VUR) which avoids the need for urethral catheterization (currently required to reliably determine the presence of VUR), and which thus avoids the anxiety of parents and patients that causes many families to refuse such evaluation.

Patients and methods Fifty‐four children (49 girls and five boys, mean age 7.2 years, range 4–14) previously evaluated as having VUR volunteered to participate; no child was symptomatic at the time of the study. Refluxing units were known to be present by voiding cysto‐urethrography (within 1 year, mean …