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The Large Aortopulmonary Window Without Pulmonary Vascular Disease, Yahya Ünlü, Naci̇ Cevi̇z, Bi̇lgehan Erkut, Yusuf Veli̇oğlu, Hi̇kmet Koçak Jan 2001

The Large Aortopulmonary Window Without Pulmonary Vascular Disease, Yahya Ünlü, Naci̇ Cevi̇z, Bi̇lgehan Erkut, Yusuf Veli̇oğlu, Hi̇kmet Koçak

Turkish Journal of Medical Sciences

LÜ^1 Naci CEVİZ^2 Bilgehan ERKUT^1 Yusuf VELİOĞLU^1 Hikmet KOÇAK^1 Departments of ^1Cardiovascular Surgery, ^2Pediatric Cardiology, Faculty of Medicine, Atatürk University, Erzurum - TURKEY


Ocular Toxocariasis With Bilateral Virtually Symmetrical Optic Nerve Head Granulomas, Gülay Güllülü, İlknur Akyol Salman, Ahmet Özbek, Nesli̇han Astam, Akin Levent Jan 2001

Ocular Toxocariasis With Bilateral Virtually Symmetrical Optic Nerve Head Granulomas, Gülay Güllülü, İlknur Akyol Salman, Ahmet Özbek, Nesli̇han Astam, Akin Levent

Turkish Journal of Medical Sciences

LLÜLÜ^1 İlknur AKYOL^1 Ahmet ÖZBEK^2 Neslihan ASTAM^1 Akın LEVENT^3 Departments of ^1Ophthalmology, ^2Microbiology and Clinical Microbiology, ^3Radiology, Faculty of Medicine, Atatürk University, Erzurum - TURKEY


Primary Malignant Schwannoma Of The Small Bowel: A Case Report, Fahri̇ Yilmaz, Ali̇ Kemal Uzunlar, Yaşar Bükte, Selver Özeki̇nci̇, Yilmaz Akgün Jan 2001

Primary Malignant Schwannoma Of The Small Bowel: A Case Report, Fahri̇ Yilmaz, Ali̇ Kemal Uzunlar, Yaşar Bükte, Selver Özeki̇nci̇, Yilmaz Akgün

Turkish Journal of Medical Sciences

Malignant Schwannoma of the Small Bowel Fahri YILMAZ^1 Ali Kemal UZUNLAR^1 Yaşar BÜKTE^2 Selver ÖZEKİNCİ^1 Yılmaz AKGÜN^3 Departments of ^1Pathology, ^2Radiology, ^3General Surgery Faculty of Medicine, Dicle University, Diyarbakır - TURKEY


Nitric Oxide I: Advances In The Measurements For Clinical Applications, Ayşe Baysal Jan 2001

Nitric Oxide I: Advances In The Measurements For Clinical Applications, Ayşe Baysal

Turkish Journal of Medical Sciences

Nitric oxide (NO) is a colorless gas with high affinity to ferrous hemoproteins. This simple molecule is a powerful messenger in the body. This study reviews a literature search using keywords and abstracts in English through Medline. Recent advances in the therapeutic uses of inhaled nitric oxide in lung diseases and other pathologic states urges the efficient and convenient use of nitric oxide in hospital practice. In addition, methods of inhaled nitric oxide delivery, chemiluminescence and electrochemical analyzers were reviewed. The performance characteristics of different equipment were compared. The novel methods of nitric oxide measurements that utilize simple and cheaper …


Purification And Characterization Of Carbonic Anhydrase From Human Erythrocyte Plasma Membrane, Nazan Demi̇r, Yaşar Demi̇r, Fatma Coşkun Jan 2001

Purification And Characterization Of Carbonic Anhydrase From Human Erythrocyte Plasma Membrane, Nazan Demi̇r, Yaşar Demi̇r, Fatma Coşkun

Turkish Journal of Medical Sciences

Carbonic anhydrase is the basic enzyme in inhalation function. Untill now no research had been done to determine whether CA is in the human erythrocyte plasma membrane or not. Carbonic anhydrase (CA) was purified from human erythrocyte plasma membrane and described in this study. For this purpose, the blood samples taken from young human test subjects were hemolyzed, then the membrane fraction was separated, and this fraction was repeatedly washed. The enzyme (CA) was removed from the membrane with buffered TritonX-100 (1%), which was purified with a factor of 119.19 by affinity chromatography. The CA obtained from the erythrocyte membrane …


Qsars Of Some 5- Or 6-Methyl-2-Substituted Benzoxazoles/Benzimidazoles Against Candida Albicans, Özlem Temi̇z Arpaci Jan 2001

Qsars Of Some 5- Or 6-Methyl-2-Substituted Benzoxazoles/Benzimidazoles Against Candida Albicans, Özlem Temi̇z Arpaci

Turkish Journal of Medical Sciences

QSAR analysis of some 5- or 6-methyl-2-substituted benzoxazoles/ benzimidazoles was studied for the antifungal activity against C. albicans using Hansch analysis. Prediction for the lead optimization in this QSAR analysis was described by the description of various hydrophobic, electronic, steric and structural parameters related to positions R_1, R_2, R_5, R_6, X, Y. The cross-validation method was also applied to the data set in order to prove the predictive power by using the BILIN statistical software. The resulting QSAR revealed that substitution at position Y with the CH_2 group was significant for the improved antifungal activity. Moreover, hydrophobic properties of the …


Brain Stem And Cerebral Cortex Histamine Concentrations In The Rem Sleep Deprived Rats, Hale Sayan, Ethem Geli̇r, Aydan Babül Jan 2001

Brain Stem And Cerebral Cortex Histamine Concentrations In The Rem Sleep Deprived Rats, Hale Sayan, Ethem Geli̇r, Aydan Babül

Turkish Journal of Medical Sciences

Histamine is a biogenic amine widely distributed in the central nervous system that acts in a neuroregulatory role in controlling the waking state. The aim of this study was to determine whether 120 h of REM sleep deprivation (REMSD) causes changes in histamine concentrations in rat brain stems and cerebral cortex areas that are involved in the homeostatic regulation of sleep. A number of rats were subjected to 120 h of REM sleep deprivation using the flower pot water tank technique. This method used to induce REMSD is believed to be stressful. To control for the stress caused by the …


Hormonal Profile And Agnor Values In Pituitary Adenomas, Sema Hücümenoğlu, Handan Kaya, Esi̇n Koti̇loğlu, Gülben Erdem, Evri̇m Demi̇ray, Gülsün Eki̇ci̇oğlu Jan 2001

Hormonal Profile And Agnor Values In Pituitary Adenomas, Sema Hücümenoğlu, Handan Kaya, Esi̇n Koti̇loğlu, Gülben Erdem, Evri̇m Demi̇ray, Gülsün Eki̇ci̇oğlu

Turkish Journal of Medical Sciences

Nucleolar organizer regions (NORs) are chromosomal segments in which ribosomal RNA is encoded. The AgNOR technique, which reveals these regions, has rarely been used in diagnosis and preceding the prognosis of pituitary adenoma. The purpose of this study was to evaluate the correlation of hormonal profile with the AgNOR counts, and the correlation of recurrence with the AgNOR counts and to determine the concordance between the evaluations of two different observers. This study included 33 patients wıth pituitary adenoma. The slides were stained with hematoxylin and eosin, silver colloid method for NORs and immunohistochemistry for the hormone expressions. Consistency was …


Relationship Between Psychopathology And Regional Cerebral Blood Flow Detected By Tc-99m Hmpao Spect In Patients With Predominantly Positive Or Negative Schizophrenic Symptoms, Nazan Aydin, Erhan Varoğlu, Mehmet Dumlu Aydin, Hati̇ce Uslu, Ali̇ Çayköylü Jan 2001

Relationship Between Psychopathology And Regional Cerebral Blood Flow Detected By Tc-99m Hmpao Spect In Patients With Predominantly Positive Or Negative Schizophrenic Symptoms, Nazan Aydin, Erhan Varoğlu, Mehmet Dumlu Aydin, Hati̇ce Uslu, Ali̇ Çayköylü

Turkish Journal of Medical Sciences

We investigated whether rCBF values obtained with the SPECT technique are different in schizophrenics with predominantly positive or negative symptoms and assessed the biological underpinnings of psychotic phenomena, which has been done repeatedly in the past, with somewhat varied results. Twenty-nine schizophrenic patients were examined to investigate the relationship between regional cerebral blood flow (rCBF) and psychopathology according to SANS, SAPS and BPRS scores. Using the Tc-99m HMPAO SPECT method at rest, rCBF was assessed in 15 patients with predominantly positive (group I) and 14 with predominantly negative (group II) symptoms. Ten age-matched normal healthy volunteers comprised the control group. …


Lung Carbon Dioxide Elimination Corralates With Physiologic Dead Space Volume During Mechanical Ventilatory Support, Murat Sungur, Muhammed Güven Jan 2001

Lung Carbon Dioxide Elimination Corralates With Physiologic Dead Space Volume During Mechanical Ventilatory Support, Murat Sungur, Muhammed Güven

Turkish Journal of Medical Sciences

Increased mean airway pressure (Paw) predisposes to increased alveolar dead space volume and, hence, physiologic dead space volume (V{Dphys}. This is the result of overdistending alveoli, converting Zone 2 and Zone 3 units to Zone 1 units. Lung carbon dioxide elimination (LCO_2) is a reflection of pulmonary capillary blood flow. It is hypothesized that as Zone 1 units form or V{Dphys} increases, LCO_2 decreases proportionately and eventually PaCO_2 increases. The purpose of this study is to determine if LCO_2 correlates with V{Dphys} during mechanical ventilation. Six sheep (66.3 ± 6.5 kg), anesthetized with sodium thiopental and paralyzed using pancronium, had …


Evaluation Of Thyroid Hormones And Goitre In A Rural Community In A Region Of Anatolia, Meti̇n Kilinç, Güneş T. Yüregi̇r, Fi̇kret Ezberci̇, Hasan Ekerbi̇çer, Mehmet Aki̇f Büyükbeşe Jan 2001

Evaluation Of Thyroid Hormones And Goitre In A Rural Community In A Region Of Anatolia, Meti̇n Kilinç, Güneş T. Yüregi̇r, Fi̇kret Ezberci̇, Hasan Ekerbi̇çer, Mehmet Aki̇f Büyükbeşe

Turkish Journal of Medical Sciences

This study was conducted in an endemic goitre area to determine thyroid profiles TSH, freeT4 (fT4), T4, fT3 and T3, as well as the degree of the severity of hypothyroidism and the prevalence of the disease. Tonbak is a small village in Kahramanmaraş. The iodine content of the water is < 1 mg/L. A randomly selected group of 121 subjects aged 16-55 were included in the study. The percentage of goitre was 71.1% upon physical examination. Subjects with primary hypothyroidism were 16.5%. Mean scores of fT4 were 8.9±2.6 pmol/l (range: 2.7-12.9) and mean scores of TSH were 18.1±26.1 mU/ml (range: 4.33-100


Acrodermatitis Enteropathica, Enver Şi̇mşek Jan 2001

Acrodermatitis Enteropathica, Enver Şi̇mşek

Turkish Journal of Medical Sciences

No abstract provided.


Isolated Hydatic Cyst In The Subcutaneous Tissue, Tanju Acar, Ramazan Taçyildiz, Sali̇h Tuncal Jan 2001

Isolated Hydatic Cyst In The Subcutaneous Tissue, Tanju Acar, Ramazan Taçyildiz, Sali̇h Tuncal

Turkish Journal of Medical Sciences

No abstract provided.


Production Of Monoclonal Antibody Specific For Human Hemoglobin, Selma Öztürk, Beyazit Çirakoğlu Jan 2001

Production Of Monoclonal Antibody Specific For Human Hemoglobin, Selma Öztürk, Beyazit Çirakoğlu

Turkish Journal of Medical Sciences

Hemoglobin is not normally present in sputum, urine or feces except in minute amounts. Demonstration of the presence of hemoglobin in these materials is an important diagnostic clue that usually implies bleeding within the respiratory, urinary or gastroentestinal tract, respectively. In this work, a hybridoma line secreting monoclonal antibody (Mab) highly specific for human hemoglobin A (hHbA) was generated by fusion of immunized BALB/c mouse splenic lymphocytes with non-secreting mouse myeloma cells followed by selection in hypoxanthine-aminopterin-thymidine (HAT) medium and the screening of culture fluids for hHb A affinity in ELISA. The Mab produced by MAM 2/3B6 is highly specific …


Flow Cytometric Analysis Of The Effects Of Methotrexate And Vepesid On The Hep-2 Cell Cycle, Ni̇zami̇ Duran, Adi̇l M. Allahverdi̇yev, Sali̇h Çeti̇ner Jan 2001

Flow Cytometric Analysis Of The Effects Of Methotrexate And Vepesid On The Hep-2 Cell Cycle, Ni̇zami̇ Duran, Adi̇l M. Allahverdi̇yev, Sali̇h Çeti̇ner

Turkish Journal of Medical Sciences

Objective: To determine the mechanism of action of Methotrexate and Vepesid on the HEp-2 cells isolated from human laryngeal cancer cells morphologically and flow cytometrically (G1, G2, S and PI). Materials and Methods: The HEp-2 continuous cell line was used. Cultivation of the cells was realized in EMEM medium with 10% fetal bovine serum at an atmosphere of 37ºC with 5% CO_2. Six different concentrations of Vepesid and Methotrexate were prepared by diluting with deionized water (5 µg/ml, 50 mg/ml, 500 µg/ml). The morphological and cell cycle parameters of HEp-2 cells were determined by inverted microscope and flow cytometer respectively. …


In Vitro Mic Determination Of Haemophilus Influenzae Strains Using E-Test, Ni̇lay Çöplü, Orhan Cem Aktepe, Selda Uluutku, Engi̇n Güvener Jan 2001

In Vitro Mic Determination Of Haemophilus Influenzae Strains Using E-Test, Ni̇lay Çöplü, Orhan Cem Aktepe, Selda Uluutku, Engi̇n Güvener

Turkish Journal of Medical Sciences

H. influenzae is a fastidious bacteria, so the selection of a reliable method for in-vitro susceptibility tests is particularly important. The E-test is a practical method for detecting in-vitro antimicrobial susceptibility of antibiotics by MIC values. This study was performed using the E-test for direct patient management and in order to obtain epidemiological data on H. influenzae. The detection of antimicrobial agent resistance among fifty-seven H. influenzae isolates from lower respiratory tract infections in childhood was studied by the E-test. The E-test was performed on HTM agar according to the instruction manual recommendations. The susceptibility ratios and the MIC90 values …


Effects Of Experimental Diabetes And Insulin Treatment On Rabbit Renal Morphology: A Quantitative And Qualitative Study, Hüseyi̇n Eray Bulut, Bi̇lge Onarlioğlu, Celal Kaloğlu, Öztürk Özdemi̇r, Semi̇h Ayan Jan 2001

Effects Of Experimental Diabetes And Insulin Treatment On Rabbit Renal Morphology: A Quantitative And Qualitative Study, Hüseyi̇n Eray Bulut, Bi̇lge Onarlioğlu, Celal Kaloğlu, Öztürk Özdemi̇r, Semi̇h Ayan

Turkish Journal of Medical Sciences

Diabetes causes metabolic defects and related vascular alterations such as atherosclerosis. These vascular alterations may also reflect the renal structural degeneration under the influence of diabetes. Therefore, the aim of the present study was to determine qualitatively and quantitatively the effect of experimental diabetes on rabbit renal cortical structure, and also to evaluate the reversal rate of the renal structural alterations by daily insulin treatment. Eighteen rabbits, bred and fed in standard laboratory conditions, were divided into 3 groups each containing 6 animals. While control group animals received no treatment, the rest were injected with a single dose of intravenous …


Analysis Of Ras Gene Mutation In Human Oral Tumours By Polymerase Chain Reaction And Direct Sequencing, Si̇nan Süzen, James M. Parry Jan 2001

Analysis Of Ras Gene Mutation In Human Oral Tumours By Polymerase Chain Reaction And Direct Sequencing, Si̇nan Süzen, James M. Parry

Turkish Journal of Medical Sciences

Genetic alterations in proto-oncogenes or tumour suppressor genes are believed to be one of the key events in the multistage process of carcinogenesis. Activating point mutations occurring in either one of the three ras proto-oncogene families are common genetic alterations in human and animal neoplasms. However, the mechanisms leading to oral cancer are not completely understood. Activation of the ras oncogene in oral carcinogenesis, although absent or rare in the western world, accounts for up to 35% of all malignancies in India and South Asia. Recognised aetiological agents of oral cancer include tobacco and alcohol. Tobacco-associated compounds such as nitrosamines …


Cytomorphologic Analysis Of Papanicolaou Stained Smears Collected From Floor Of The Mouth Mucosa In Patients With Or Without Oral Malignancy, Nur Mollaoğlu, Jonathan George Cowpe, Rita Walker Jan 2001

Cytomorphologic Analysis Of Papanicolaou Stained Smears Collected From Floor Of The Mouth Mucosa In Patients With Or Without Oral Malignancy, Nur Mollaoğlu, Jonathan George Cowpe, Rita Walker

Turkish Journal of Medical Sciences

Cytology has been found to be a reliable and accurate technique when used to diagnose early malignant transformation in areas of the body where visual examination is difficult or impossible. The factors initiating neoplastic growth are still not clearly understood. Thus, automated instruments, capable of objective and quantitative cell analysis, have been used in descriptive morphology, for the assessment of tumour cell heterogeneity. Smears were collected from a group of 33 patients presenting with squamous cell carcinoma. Nine females and 24 males presenting with squamous cell carcinoma of the floor of the mouth underwent quantitative cytological assessment. These slides were …


Igg Subclass Levels In Elf In Copd, Demet Karnak, Sumru Beder, Oya Kayacan, Levent Karaca Jan 2001

Igg Subclass Levels In Elf In Copd, Demet Karnak, Sumru Beder, Oya Kayacan, Levent Karaca

Turkish Journal of Medical Sciences

Objective: Deficiency of immunoglobulin (Ig) may be responsible for recurrent infections in chronic obstructive pulmonary disease (COPD). Our aim was to investigate the level of IgG subclass (IgGsc) in the epithelial lining fluid (ELF) and to try to find a possible relation between these levels and serum or bronchoalveolar lavage (BAL) IgGsc levels in COPD patients with recurrent acute exacerbation. Methods: Twenty-four clinically stable non-smoking COPD patients who had developed recurrent exacerbations three or four times a year and 17 individuals without COPD were enrolled as the experimental and control groups (Group I and II) respectively. The BAL procedure was …


Glomerular Hla Dr Dp Dq Expression In Renal Diseases, Sülen Sarioğlu, Feza Kirimca, Caner Çavdar, Mehmet Türkmen Jan 2001

Glomerular Hla Dr Dp Dq Expression In Renal Diseases, Sülen Sarioğlu, Feza Kirimca, Caner Çavdar, Mehmet Türkmen

Turkish Journal of Medical Sciences

The expression of major histocompatibility antigens class II (MHC II) in renal diseases has been studied extensively in the tubulo-interstitial compartment, while there are few articles about their expression in the glomeruli. In this series, glomerular expression of HLA DR DP DQ is evaluated in a total of 62 cases of pyelonephritis, glomerulonephritis, tubulointerstitial nephritis and systemic diseases with renal manifestations in order to identify their relationship with disease status and renal scarring. Formaline fixed paraffin embedded tissue sections from renal biopsy and nefrectomy specimens were stained by an antibody against HLA DR DP DQ by the streptavidin biotin method. …


Determination Of The Absorption Of Zn By Preterm Infants, Using 70zn Enriched Tracer, Ulvi̇ Ulusoy, John E. Whitley Jan 2001

Determination Of The Absorption Of Zn By Preterm Infants, Using 70zn Enriched Tracer, Ulvi̇ Ulusoy, John E. Whitley

Turkish Journal of Medical Sciences

Absorption of zinc by preterm infants from a synthetic milk labelled extrinsically with 70Zn tracer was determined by faecal monitoring. Six male preterm babies with a mean gestational age of 31±2.9 weeks and a mean birth weight of 1.23±0.24 kg were studied for three balance periods of 72 h with intervals ranging from 6 to 30 days. The babies were fed with the milk containing zinc with added 70Zn tracer. The net (NA) and true (TA) absorption, and endogenous loss (EL) of zinc were determined by the classical (chemical) balance and isotopic approaches. The mean TA, NA and EL were …


A Comparative Clinical And Histopathological Examination Of Hemangioma And Chronic Inflammatory Enlargement Of Gingiva, Umur Sakallioğlu, Gökhan Açikgöz, Tuğrul Kirtiloğlu, Musa Aldikaçti Jan 2001

A Comparative Clinical And Histopathological Examination Of Hemangioma And Chronic Inflammatory Enlargement Of Gingiva, Umur Sakallioğlu, Gökhan Açikgöz, Tuğrul Kirtiloğlu, Musa Aldikaçti

Turkish Journal of Medical Sciences

Chronic inflammatory gingival enlargement (CIGE) occasionally exhibits some similarities with hemangioma (Hm) by means of the clinical and histopathological features of gingiva. When compared with hemangioma, CIGE is more frequently encountered by the dental profession. However, Hm is rarely seen on gingiva and it has a non-inflammatory nature and mostly congenital origin. The present paper reports the clinic and histopathologic features of CIGE and Hm of gingiva in patients referred to our clinic suffering primarily from gingival overgrowth. Twenty-one patients were diagnosed as having CIGE (in a 4-month period) and 10 patients were diagnosed as having Hm (in a 12-month …


A Father Born To Consanguineous Parents Had Double Translocation 21;22 [44,Xy, T(21q;22q), T(21q;22q)] Due To Familial Translocation In Four Generations, Cumhur Gündüz, Ferda Özkinay, Özgür Çoğulu, Gül Sapmaz, Tufan Çankaya, Ci̇hangi̇r Özkinay Jan 2001

A Father Born To Consanguineous Parents Had Double Translocation 21;22 [44,Xy, T(21q;22q), T(21q;22q)] Due To Familial Translocation In Four Generations, Cumhur Gündüz, Ferda Özkinay, Özgür Çoğulu, Gül Sapmaz, Tufan Çankaya, Ci̇hangi̇r Özkinay

Turkish Journal of Medical Sciences

No abstract provided.


The Histopathologic And The Immunohistochemical Features Of Secretory Meningiomas, M. Şerefetti̇n Canda, Meri̇h Güray, D.Ümi̇t Acar Jan 2001

The Histopathologic And The Immunohistochemical Features Of Secretory Meningiomas, M. Şerefetti̇n Canda, Meri̇h Güray, D.Ümi̇t Acar

Turkish Journal of Medical Sciences

No abstract provided.


Cold Shock Proteins, N. Nuray Ulusu, E. Ferhan Tezcan Jan 2001

Cold Shock Proteins, N. Nuray Ulusu, E. Ferhan Tezcan

Turkish Journal of Medical Sciences

From prokaryotes to eukaryotes or from invertebrates to vertebrates, all organisms have developed various adaptive mechanisms to survive within a wide range of growth temperatures. An important part of the cold adaptation mechanism occurs at the level of the cytoplasmic membrane. Cold shock affects the membrane composition and organisation to maintain the optimum membrane function. Cold shock also affects cell division. The temperature downshift results in a growth lag. During the lag phase the organism changes the composition of the cytoplasmic membrane and synthesis sets of specific proteins called cold shock proteins or cold induced proteins.


Effects Of Oral L-Glutamine, Insulin And Laxative On Bacterial Translocation In Acute Pancreatitis, Fati̇h Mehmet Avşar, İ. Hakan Özel, Mahmut Baykan, Oral Saygun, Mustafa Şahi̇n, Süleyman Hengi̇rmen, Ömür Ertuğrul, Mehmet Gürbi̇lek, S. Neşe Aydin Jan 2001

Effects Of Oral L-Glutamine, Insulin And Laxative On Bacterial Translocation In Acute Pancreatitis, Fati̇h Mehmet Avşar, İ. Hakan Özel, Mahmut Baykan, Oral Saygun, Mustafa Şahi̇n, Süleyman Hengi̇rmen, Ömür Ertuğrul, Mehmet Gürbi̇lek, S. Neşe Aydin

Turkish Journal of Medical Sciences

Aim: To investigate the effects of oral L-glutamine, insulin and laxative on the bacterial population of intestinal lumen and on bacterial translocation in acute pancreatitis. Materials and Methods: Forty Sprague-Dawley adult male rats were divided into 4 groups. Experimental pancreatitis was induced by ligating the main biliopancreatic duct. All groups were given the standard rat diet and tap water. In addition, Group II was given. 15 mg/kg/day of L-glutamine via a catheter enterally, Group III was given 3 ml of laxative via a catheter enterally, and Group IV was given 3 IU/kg/day of NPH insulin via a catheter enterally. The …


The Type And Frequency Of Infections Occurring In Collagen Tissue Diseases, Refi̇k Ali̇ Sari, Mehmet Şahi̇n, Göksal Keski̇n, İlhami̇ Ki̇ki̇, Murat Turgay Jan 2001

The Type And Frequency Of Infections Occurring In Collagen Tissue Diseases, Refi̇k Ali̇ Sari, Mehmet Şahi̇n, Göksal Keski̇n, İlhami̇ Ki̇ki̇, Murat Turgay

Turkish Journal of Medical Sciences

Corticosteroids, widely used in the treatment of collagen tissue diseases, increase the number of neutrophils and decrease the total numbers of lymphocytes, monocytes, eosinophils and basophils. In addition, corticosteroids alter important functional activities of both lymphocytes and monocytes. They suppress the bactericidial activities of phagocytes. In this manner, the resistance to infections is reduced. Cytotoxic drugs can have profound effects on the production and function of both phagocyte cells and lymphocytes. We followed up 115 patients with collagen tissue disease for two years and 22 of them had infections. Eight of these 22 patients had urinary tract infection, six had …


Isolated Caudate Nucleus Hemorrhage During The Acute Period Of Stroke, Selçuk Çomoğlu, Şenay Özbakir Jan 2001

Isolated Caudate Nucleus Hemorrhage During The Acute Period Of Stroke, Selçuk Çomoğlu, Şenay Özbakir

Turkish Journal of Medical Sciences

Caudate hemorrhage is a rare stroke syndrome that accounts for only 3-7% of all primary intracerebral hematomas. In this study, we evaluated eight patients with isolated caudate nucleus hemorrhage for their clinical presentation and neurological findings. Material and methods: Eight patients, who were admitted to our department with isolated caudate nucleus hemorrhage, were evaluated for their clinical presentation and present risk factor findings on neurological examination and prognosis. Results: The most common symptoms on admission were headache and vomiting (five patients), whereas the most common findings on neurological examination were unconsciousness and neck stiffness (four patients). Two patients who were …


The Effect Of Fixed Restoration Materials On The Il-1\Beta Content Of Gingival Crevicular Fluid, Jüli̇de Özen, Bedri̇ Beydemi̇r, Muhi̇tti̇n A. Serdar, Mehmet Dalkiz, Işil Saygun, Ati̇lla Özdemi̇r Jan 2001

The Effect Of Fixed Restoration Materials On The Il-1\Beta Content Of Gingival Crevicular Fluid, Jüli̇de Özen, Bedri̇ Beydemi̇r, Muhi̇tti̇n A. Serdar, Mehmet Dalkiz, Işil Saygun, Ati̇lla Özdemi̇r

Turkish Journal of Medical Sciences

Cast alloys used in dentistry come into close and prolonged contact with the gingiva and the oral mucosa, and certain alloys have been claimed to cause inflammation of gingival and periodontal tissues. However, only little information is available on the molecules mediating the mechanism of such an effect. For this reason, the aims of this study were to determine 1L-1\beta levels in the gingival crevicular fluid (GCF) before and after the placement of base, high-noble metal-ceramic and all-ceramic crowns. Thirty patients requiring an artificial crown for a maxillary second premolar were suitable for the present study; 18 were male and …