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Articles 3181 - 3210 of 256530
Full-Text Articles in Entire DC Network
Ratfish (Chimaera Monstrosa) Chondocranium, Riley B. Glogowski, David W. Kerstetter
Ratfish (Chimaera Monstrosa) Chondocranium, Riley B. Glogowski, David W. Kerstetter
All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series
No abstract provided.
Una To Put Names On 2 Buildings, Jennifer Edwards
Una To Put Names On 2 Buildings, Jennifer Edwards
Documents
the naming of the Academic Commons Building and the new Science and Technology Building at UNA
The Science And Technology Building University Of North Alabama, Barbie Hampel-University Advancement
The Science And Technology Building University Of North Alabama, Barbie Hampel-University Advancement
Documents
Brochure and floor plans for the New Science and Technology Building at UNA
University Of North Alabama Science And Technology Building Grand Opening And Ribbon Cutting, University Of North Alabama
University Of North Alabama Science And Technology Building Grand Opening And Ribbon Cutting, University Of North Alabama
Documents
Invitation to the Grand Opening and Ribbon Cutting for the new Science and Technology Building at UNA
Evaluating Impact Of Sustainability Practices And Operational Efficiency On Firm Value In Indonesia’S Mining Sector, Erika Windyasari, Yosman Bustaman
Evaluating Impact Of Sustainability Practices And Operational Efficiency On Firm Value In Indonesia’S Mining Sector, Erika Windyasari, Yosman Bustaman
Journal of Environmental Science and Sustainable Development
Sustainability practices are increasingly prominent in investor assessments of firm value Nevertheless, empirical evidence regarding which specific environmental practices are incorporated into capital market valuations remains inconclusive, particularly within mining sectors in emerging markets. This study investigates the correlation between sustainability practices energy efficiency, water management, waste management, renewable energy adoption and environmental quality (PROPER rating) together with operational efficiency and firm value in Indonesian listed mining firms. The analysis uses panel data for 23 firms over 2017–2023. Firm value is measured by Tobin’s Q, while operational efficiency is measured using Data Envelopment Analysis (DEA). The correlation is estimated using …
A Regional Scoping Review Of School-Based Nutrition Interventions Conducted Across Nordic Countries, Basil H. Aboul-Enein, Stephen Gambescia, Nada Benajiba, Norah Eid Aljohani, Teresa Keller, Patricia J. Kelly
A Regional Scoping Review Of School-Based Nutrition Interventions Conducted Across Nordic Countries, Basil H. Aboul-Enein, Stephen Gambescia, Nada Benajiba, Norah Eid Aljohani, Teresa Keller, Patricia J. Kelly
College of Nursing Faculty Papers & Presentations
BACKGROUND AND AIMS: While Nordic countries have a relatively high socioeconomic status population, they are challenged by the health deficit of rising obesity and overweight among young people. The aim of this regional scoping review is to identify best practices for designing and implementing effective school nutrition programs in Nordic countries and identify gaps for further research.
METHODS: Using the PRISMA-ScR guidelines, a scoping review was conducted across nine academic databases between 1980 and May 2025.
RESULTS: Fifty-three studies met the inclusion criteria, from small pilot interventions to large national or international cohorts involving thousands of students across the five …
New Species Of Kronosvirus Bacteriophages That Infect Caulobacter Strain Cbr1, Tannaz Mohammadi, Austin Millwood, Maherah Shaik, Bert Ely
New Species Of Kronosvirus Bacteriophages That Infect Caulobacter Strain Cbr1, Tannaz Mohammadi, Austin Millwood, Maherah Shaik, Bert Ely
Faculty Publications
Caulobacter segnis strain CBR1 enhances the germination rate and total biomass of Arabidopsis plants. Since bacteriophages are usually present in the rhizosphere, we isolated three additional bacteriophages, designated TMCBR2, TMCBR3, and W2, that can replicate using CBR1 as the host strain. The genome sizes and morphologies of the new phages were similar to those of the previously isolated Kronos phage, and when we compared the nucleotide sequence of these new phage genomes, we found only minor differences among the four phage genomes. Pairwise sequence comparisons indicated that the phage genomes should be grouped into three separate species within Kronosvirus genus. …
Soil Nutrient Sufficiency Does Not Ensure Plant Nutrient Status, Chandralekha Joga Miss
Soil Nutrient Sufficiency Does Not Ensure Plant Nutrient Status, Chandralekha Joga Miss
Scholars Week
Soil testing is commonly used to guide nutrient management. However, plants may not use nutrients in the same way that soil tests predict. This can happen when nutrients interact and limit uptake. This study evaluated whether soil test results match plant nutrient status under different compost levels, with a focus on nutrient antagonism. Soils from three compost histories were used: no compost (T1), moderate compost (T2), and long-term high compost from repeated hog manure application (T3). Soils were mixed with ProMix and Perlite (1:1:1), and Chijimisai was grown under greenhouse conditions. Plant height and chlorophyll (SPAD) were measured weekly. Soil …
Phytochemical Effects Of Culinary Spices On Kale Germination And Early Growth, Chandralekha Joga Miss
Phytochemical Effects Of Culinary Spices On Kale Germination And Early Growth, Chandralekha Joga Miss
Scholars Week
Phytochemicals present in culinary spices can influence seed germination and early plant development through complex biochemical interactions. This study evaluated the effects of aqueous decoctions of Ajwain (Trachyspermum ammi), Clove (Syzygium aromaticum), Fenugreek (Trigonella foenum-graecum), Yellow Mustard (Sinapis alba), and Brown Mustard (Brassica juncea) on germination and early growth of Kale (Brassica oleracea var. acephala) under greenhouse conditions. Treatments were applied at two concentrations (2 g/100 mL and 5 g/100 mL) with distilled water as control in a completely randomized design with three replications (n = 8). Seeds were soaked in spice decoctions for 2 hours prior to sowing, and …
Impact Of One Nucleotide On Organ Enumeration And Phyllotaxy In Arabidopsis Thaliana, Hazel R. Frans, Tara Phelps-Durr
Impact Of One Nucleotide On Organ Enumeration And Phyllotaxy In Arabidopsis Thaliana, Hazel R. Frans, Tara Phelps-Durr
SACAD: Scholarly Activities
Arabidopsis thaliana is a model organism used by scientists to study plant genetics, development, and physiology. CRISPR-Cas9 is a biotechnology tool adapted from a bacterial defense mechanism to precisely edit DNA using a guide mRNA and a Cas9 protein. This project aims to create CRISPR-CAS9 mutations in the APETALA3 (AP3) gene of the model plant Arabidopsis thaliana. AP3 is a class B gene critical to the petal and stamen development of Arabidopsis flowers. The AP3 protein contains a MADS domain, which binds directly to DNA and may be responsible for the expression of the CaRG-box genes. AP3 works in conjunction …
The Effect Of Low And High-Carbohydrate Diets On Memory Performance In College Students, Samia Baugh, Zoe Zajko, Jamie Analuisa, Ivanna Jacome
The Effect Of Low And High-Carbohydrate Diets On Memory Performance In College Students, Samia Baugh, Zoe Zajko, Jamie Analuisa, Ivanna Jacome
Department of Nutrition Student Projects
Carbohydrates are the primary source of energy for the brain and play an important role in processes related to memory performance. The purpose of this study is to examine the impact of a low-carbohydrate diet compared to a high-carbohydrate diet on memory performance in college students aged 18–22 years. For the purposes of this study, a low-carbohydrate diet is defined as a diet providing fewer than 130 grams of carbohydrates per day, while a high-carbohydrate diet provides approximately 325 grams of carbohydrates. This population is particularly important to study because college students experience high academic demands that require strong memory …
Morphology, Phylogeny And Distribution Of Scaeurgus (Cephalopoda: Octopoda) In Southeast Pacific Seamounts, Sergio A. Carrasco, Christian M. Ibáñez, Andrea I. Varela, Jan M. Tapia-Guerra, Erin E. Easton, Javier Sellanes
Morphology, Phylogeny And Distribution Of Scaeurgus (Cephalopoda: Octopoda) In Southeast Pacific Seamounts, Sergio A. Carrasco, Christian M. Ibáñez, Andrea I. Varela, Jan M. Tapia-Guerra, Erin E. Easton, Javier Sellanes
School of Earth, Environmental, & Marine Sciences Faculty Publications
Octopuses of the genus Scaeurgus inhabit upper bathyal benthic habitats and are composed of five recognized species. In this study, we conducted morphological and molecular phylogenetic analyses of two individuals of Scaeurgus and provided additional field observations of the genus in seamounts of the Nazca and Salas y Gómez ridges (southeast Pacific Ocean) over the last six years. Specifically, two specimens of Scaeurgus were collected at 234 m depth in 2019 during the EPIC oceanographic cruise onboard the R/V Mirai (JAMSTEC, Japan), and five other specimens were video recorded at depths between 210 and 340 m during three oceanographic expeditions …
Predicting Soil Organic Carbon In Lower Depths From Surface Soil Features Using Machine Learning Methods, Lawrence Aula, Milena Maria Tomaz De Oliveira, Amanda C. Easterly, Cody F. Creech
Predicting Soil Organic Carbon In Lower Depths From Surface Soil Features Using Machine Learning Methods, Lawrence Aula, Milena Maria Tomaz De Oliveira, Amanda C. Easterly, Cody F. Creech
Plants, Soils, and Climate Faculty Publications
Topsoil features within a depth of 0–10 cm are vital for making soil management decisions that affect crop production. However, the use of these soil features to predict soil organic carbon (SOC) at 10–20 cm requires further investigation. The study aims to predict SOC at 10–20 cm using total nitrogen (total N), pH, cation exchange capacity (CEC), and SOC at 0–10 cm and select a suitable model for predicting SOC. This study was conducted using data from a long-term tillage, winter wheat (Triticum aestivum L.)-fallow experiment established in autumn 1970. Treatments included moldboard plow, stubble mulch, no-till, and native …
Snail Snacks: Introduced Seaweeds Facilitate Performance Of An Introduced Marine Snail, Alysha B. Putnam, Adeline Dwyer, Paulette Peckol
Snail Snacks: Introduced Seaweeds Facilitate Performance Of An Introduced Marine Snail, Alysha B. Putnam, Adeline Dwyer, Paulette Peckol
Biological Sciences: Faculty Publications
Facilitative interactions among introduced species can accelerate invasion and community change, yet positive interactions are often overlooked compared to competition and predation. In marine systems, positive facilitation is more commonly demonstrated indirectly through habitat modification, with fewer studies examining direct performance impacts. While introduced herbivores in non-marine systems consume and even prefer introduced food sources, this pattern is less studied in marine environments. In this study, we tested grazing preferences and growth responses of the introduced periwinkle Littorina littorea and the native Littorina obtusata, when fed native and introduced seaweeds from southern New England. L. littorea grazed broadly across …
A Novel Endolysin Of Phage Persinger Infecting Pseudomonas Aeruginosa: Activity Against Biofilms And Structural Prediction, Layla Abbud
James Madison Undergraduate Research Journal (JMURJ)
Endolysins are proteins that degrade bacterial cell walls. They are encoded on the genome of bacteriophages (viruses that infect and kill bacteria). At the end of the lytic cycle of a bacteriophage, endolysins cut the peptidoglycan layer of the bacterial cell wall, allowing the release of viral progeny. Pseudomonas aeruginosa is a well-known multidrug-resistant human pathogen that causes serious problems, especially in patients diagnosed with cystic fibrosis (CF). One property of P. aeruginosa is the production of biofilms, which is a defense against antibiotics. Previous research has shown that endolysins from bacteriophages can degrade biofilms. The endolysin protein from Persinger, …
Dna Barcoding Of Eight Freshwater Fish Species (Order Siluriformes) From The River Ravi, Pakistan, Hafiz Muhammad Ashraf, Hafiz Abdullah Shakir, Muhammad Irfan, Shaukat Ali, Chaman Ara, Noor Khan, Muhammad Khan, Abdul Qadir, Muhammad Zafar Saleem
Dna Barcoding Of Eight Freshwater Fish Species (Order Siluriformes) From The River Ravi, Pakistan, Hafiz Muhammad Ashraf, Hafiz Abdullah Shakir, Muhammad Irfan, Shaukat Ali, Chaman Ara, Noor Khan, Muhammad Khan, Abdul Qadir, Muhammad Zafar Saleem
Karbala International Journal of Modern Science
Pakistan's freshwater bodies host significant fish species, but molecular identification is still in its infancy, necessitating the use of morphological and molecular DNA barcoding techniques. The study confirmed the species of the order Siluriformes found in the River Ravi, Pakistan, using DNA extracted from muscle tissue, sequenced for the COI gene, and obtained accession and Barcode Index Numbers from GenBank and BOLD databases. In the BLAST search, identities ranged from 99.23–100% and 99.52–100% in the GenBank and BOLD databases, respectively. The study revealed that the Kimura 2-Parameter genetic distance increased from lower to higher taxonomic levels: within species (0.00%) < within genus (15.17%) < within family (19.77%). The study estimated average nucleotide differences (104.964) and nucleotide diversity (0.16099) but found Tajima's neutrality test to be statistically insignificant. The neighbor-joining tree displayed closely linked species under a node, whereas divergent species were grouped under distinct nodes. The COI gene-based DNA barcoding aids in Pakistan's fish resource inventory, monitoring, and management, providing valuable input for traditional methods.
Eco-Assisted Ultrasonic Synthesis, Characterization, And Electrical Conductivity Study Of Polyaniline/ Silica@Fe3o4 Q1 Nanocomposites, Ali Salim Shaway, Kholoud Dham Khamkheem, Jawad Kadhim Abaies, Athra G. Sager
Eco-Assisted Ultrasonic Synthesis, Characterization, And Electrical Conductivity Study Of Polyaniline/ Silica@Fe3o4 Q1 Nanocomposites, Ali Salim Shaway, Kholoud Dham Khamkheem, Jawad Kadhim Abaies, Athra G. Sager
Karbala International Journal of Modern Science
وفي هذه الدراسة الصوتية، أصبحت السيليكا المُنتجة بأكسيد الحديد (Fe₃O₄) ومركبات نانوية قائمة على البولي أنيلين مُطعّم بنسبة 5-15% من السيليكا المُعزز للحديد (Fe₃O₄). وأكملت نهائيا ماء أنيلين والمركبات العلمية المتنوعة الارتباط باستخدام تقنيات FT-IR وUV-Vis وXRD وSEM وTEM. وأحدثت نتائج XRD أن حجم جسيمات البولينج أنيلين الناي (PANI) يبلغ 55.5. مكثف هذا الحجم إلى 45.2 عند تطعيم بولي أنيلين بنسبة 15% وزناً من السيليكا المُغلفة بأكسيد الحديد (Fe₃O₄) مُحضّرة بطريقة جيدة بشكل جيد، مما يميل إلى التمدد بشكل ثابت في تشكيل المركب المتباين المنظم. ضاقت النطاق البصري من 3.2 إلى 2.5 إلكترون فولت مع زيادة نسبة المطعّم، مما يشير …
Ultrasonography Accompanied By Genetic Testing In Feline Polycystic Kidney Disease, Thao Phuong Vu, Thong Quang Le, Ha Nguyen Nhat Tran, Khoa Hoang Dang Le, Anh Phu Nam Bui
Ultrasonography Accompanied By Genetic Testing In Feline Polycystic Kidney Disease, Thao Phuong Vu, Thong Quang Le, Ha Nguyen Nhat Tran, Khoa Hoang Dang Le, Anh Phu Nam Bui
The Thai Journal of Veterinary Medicine
Autosomal dominant polycystic kidney disease (ADPKD), caused by the PKD1 c.10063C>A mutation, is a prevalent inherited feline disorder, but its allele frequency in Vietnam remains unidentified. This study aimed to determine the carrier frequency of this variant in British Shorthair, Maine Coon, and Ragdoll cats in Ho Chi Minh City and to correlate genotype with ultrasonographic phenotype. Ninety-seven client-owned cats were genotyped for the pkd1 mutation using PCR-RFLP. A subset of 47 cats also underwent abdominal ultrasonography to detect renal cysts. Genotypic results were correlated with sonographic findings, and risk factors were analyzed using chi-square tests and odds ratios …
Survivin And Caspases Coordinate Proteolytic Cleavage Of The Saga Chromatin Modifying Complex, Elinor Harrison, Alejandro Damian, Cj Talton
Survivin And Caspases Coordinate Proteolytic Cleavage Of The Saga Chromatin Modifying Complex, Elinor Harrison, Alejandro Damian, Cj Talton
Medical Student Research Symposium
Title: Survivin and Caspases Coordinate Proteolytic Cleavage of the SAGA Chromatin Modifying Complex
Elinor Harrison1, Alejandro Damian1, CJ Talton1, Jelly H Soffers1, Abudu I Bello1, Kara M Costanzo1, Joe Bean1, Ryan D Mohan1
1Wayne State University School of Medicine
Background: The Spt Ada Gcn5 Acetyltransferase (SAGA) chromatin modifying complex is a critical regulator of gene expression. Mutation or stoichiometric imbalance of SAGA subunits leads to a spectrum of diseases in model organisms and in humans, including neurodegeneration. SAGA contributes to gene activation through coordinated …
Assessing Functional Visual Recovery After Retinal Regeneration In Zebrafish Using The Optokinetic Response (Okr), Yeganeh Tabatabaei Alavi, Yeganeh Tabatabaei Alavi
Assessing Functional Visual Recovery After Retinal Regeneration In Zebrafish Using The Optokinetic Response (Okr), Yeganeh Tabatabaei Alavi, Yeganeh Tabatabaei Alavi
Medical Student Research Symposium
Zebrafish have a unique ability to regenerate retinal neurons through Müller glia-mediated reprogramming, a process not found in mammals. While structural regeneration has been extensively documented, the degree to which regenerated photoreceptors restore functional vision remains unclear. The optokinetic response (OKR), a reflexive eye-tracking behavior triggered by moving visual stimuli, provides a quantitative, non-invasive method to assess visual performance. This study aims to determine whether photoreceptor regeneration following acute and chronic light-induced injury results in functional restoration of vision. Adult zebrafish will be divided into three groups: uninjured control, acute injury (short-term high-intensity light), and chronic injury (long-term low-intensity light). …
Evaluation Of Soil Properties Under Forested And Cropland Areas In Murray, Kentucky, Ramson K C, Shiba Hari Dhakal, Abinash Dhungana
Evaluation Of Soil Properties Under Forested And Cropland Areas In Murray, Kentucky, Ramson K C, Shiba Hari Dhakal, Abinash Dhungana
Scholars Week
Soil health is shaped by its physical and chemical properties which are largely influenced by land use, affecting structure, fertility and water retention. The objective of this study was to determine key soil properties, and to evaluate their interrelationships in cultivated and forested areas of Western Kentucky. For this study, two representatives cultivated and two forested sites were selected with 6 replications each on September, 2025 in Murray, Kentucky. A total of 48 soil samples (24 disturbed and 24 undisturbed) were collected from the 0–7 cm soil layer. Disturbed soil samples were used to measure organic matter (OM) content in …
Comparing Soil Quality Changes In Forest And Cropland Systems Of Western Kentucky, Abinash Dhungana
Comparing Soil Quality Changes In Forest And Cropland Systems Of Western Kentucky, Abinash Dhungana
Scholars Week
Comparing Soil Quality Changes in Forest and Cropland Systems of Western Kentucky
Abinash Dhungana
Mentor: Dr. Iin P. Handayani, Ph.D.
Hutson School of Agriculture, Murray State University, Kentucky, USA
Abstract
Soil pH, soil organic carbon (SOC), and soil water at field capacity are critical indicators of soil quality, influencing nutrient availability, microbial activity, and water retention. Cropping practices play a crucial role in modifying these properties and determining overall soil functionality and its long-term sustainability. This study was conducted in 2025 in Calloway County, Western Kentucky, to investigate the effects of forest and cropland systems on these soil properties. Four …
Comparing Effects Of Crop Rotation And Continuous Monocropping On Soil Chemical Properties: A Review Of Agricultural Practices In The U.S. Corn Belt, Shiba Hari Dhakal Shiba
Comparing Effects Of Crop Rotation And Continuous Monocropping On Soil Chemical Properties: A Review Of Agricultural Practices In The U.S. Corn Belt, Shiba Hari Dhakal Shiba
Scholars Week
Soil chemical health is critical for sustaining long-term agricultural productivity in the U.S. Corn Belt, yet continuous monocropping of corn poses persistent challenges to soil organic matter, soil organic carbon, nutrient balance, and pH stability. This review synthesizes findings from long-term field studies to compare the impacts of crop rotation and continuous monocropping on soil organic matter (SOM), soil organic carbon (SOC), nutrient availability, and soil pH across the Corn Belt. Results consistently show that crop rotation enhances SOM and SOC through increased residue input, diverse root systems, and improved microbial activity, whereas continuous monocropping accelerates organic matter decomposition and …
The Effects Of Sun Exposure On The Intensity And Distribution Of Salamander Biofluorescence, Julianne Chairez
The Effects Of Sun Exposure On The Intensity And Distribution Of Salamander Biofluorescence, Julianne Chairez
Scholars Week
Salamanders have been used in a variety of different experiments to determine the health of various ecosystems. Biofluorescence was recently studied in amphibians in a study done in 2020. Not much is known about all its functions, more studies are needed to fully understand how it works and how it can be affected by environmental factors. Learning more about the functions of salamander biofluorescence could lead to a greater understanding of how pollutants and human impacts can affect salamanders and the health of their ecosystems. This project aims to focus on tiger salamander biofluorescence and how its distribution and intensity …
Comparing A Normal (2005) And A Drought (2007) Year Crop Health Using Ndvi, Pratibha Adhikari
Comparing A Normal (2005) And A Drought (2007) Year Crop Health Using Ndvi, Pratibha Adhikari
Scholars Week
Agricultural productivity in the southeastern United States is highly vulnerable to drought-induced crop stress, as interannual climate variability can markedly alter crop development and production dynamics. The main goal of this project is to assess how crop health in Calloway County changed between a normal year (2005) and an extreme drought year (2007) using Normalized Difference Vegetation Index (NDVI) and to evaluate the effectiveness of NDVI for monitoring crop stress. Cloud free Landsat images were acquired from USGS Earth Explorer. NDVI was produced for each year and a pixel-wise NDVI differencing image was created (ΔNDVI = NDVI_2007 − NDVI_2005). While …
Verifying Mutations In Arabidopsis Thaliana Gene Apetala3, Michelle Wang, Tara Phelps-Durr, Hazel Frans
Verifying Mutations In Arabidopsis Thaliana Gene Apetala3, Michelle Wang, Tara Phelps-Durr, Hazel Frans
SACAD: Scholarly Activities
The purpose of this research is to verify the mutation in the Arabidopsis thaliana APETALA3 (AP3) gene. By sequencing DNA, we confirmed the presence of an extra guanine in the mutant AP3 gene. These findings support that further investigation is needed into how the AP3 gene affects flower development in Arabidopsis thaliana.
Behavioral Analyses Of Reproductive Behaviors Of The River Dolphin Tucuxi (Sotalia Fluviatilis), Jaden Wee
Behavioral Analyses Of Reproductive Behaviors Of The River Dolphin Tucuxi (Sotalia Fluviatilis), Jaden Wee
Honors Theses
This research project investigates the reproductive behavior of the tucuxi river dolphin (Sotalia fluviatilis), whose mating strategies are poorly documented. In 2022, over Lake Amanã, Brazil, Dr. Gonzalez-Socoloske captured drone footage of a natural mating event involving multiple tucuxi individuals, which provided us a rare opportunity to study their behavior. Using Behavioral Observation Research Interactive Software (BORIS), behavioral states and point events, such as intromission, proximity, synchrony, and periods of non-visibility, were coded and quantified, enabling statistical and graphical analyses that characterize the tucuxi’s social and reproductive interaction patterns. The results indicate that 30 intromission events occurred within the 13-minute …
Using Machine Learning Algorithms To Clarify Relationships Between Soil Properties And Lead Stomach Bioaccessibility, Shehan Wijesinghe, Dibyendu Sarkar, Hadeer Saleh, Khalid Mustafa, Smitha Rao, Rupali Datta
Using Machine Learning Algorithms To Clarify Relationships Between Soil Properties And Lead Stomach Bioaccessibility, Shehan Wijesinghe, Dibyendu Sarkar, Hadeer Saleh, Khalid Mustafa, Smitha Rao, Rupali Datta
Michigan Tech Publications
Featured Application: This paper has important applications in environmental health risk assessment and urban soil remediation planning. By demonstrating how machine learning can predict lead bioaccessibility in lead paint-contaminated soil, the study provides a scalable, cost-effective alternative to laboratory-based extraction methods. Such models could support rapid screening of contaminated sites, helping prioritize high-risk areas for intervention and allocate remediation resources more efficiently. This model is expected to advance data-driven decision-making for managing lead-contaminated soils and protect vulnerable urban populations from exposure. Lead contamination in urban soils, primarily from deteriorating lead-based paint, poses a significant health risk in the United States. …
Characterization Of Srsf1’S Functions In Transcription And Alternative Splicing, Elena Bisotto
Characterization Of Srsf1’S Functions In Transcription And Alternative Splicing, Elena Bisotto
Electronic Theses and Dissertations
Serine/Arginine splicing factor 1 (SRSF1) is an RNA-binding protein (RBP) that serves as a central regulator of RNA biogenesis. SRSF1 has been implicated in cell replication, motility, ageing, immune function, and other physiological processes, while its dysregulation is associated with multiple cancers and autoimmune diseases. In this study, we characterized the global impact and structural requirements of SRSF1-mediated gene regulation to elucidate its proto-oncogenic functions.
Utilizing a time-course RNA sequencing (RNA-seq) approach in HEK293 cells, we identified 28 primary transcriptional targets of SRSF1, 18 of which were consistently upregulated in the established cancer cell models PC-3 and MCF-7. These targets …
Anti-Inflammatory And Insulin-Modulating Effects Of Tithonia-Curcuma-Moringa (Tcm) Formulation In Type 2 Diabetes: An Experimental Study In Mice, Rif’Atul Hawani Burhan, Nabila Shafa Yumna Salsabila, Devita Zulfa Pratama, La Tazkia Aulia Wibowo, Yulian Ervin Maulana, Moh Dliyauddin, Noviana Dwi Lestari, Agung Pramana Warih Marhendra, Aris Soewondo, Hideo Tsuboi, Muhaimin Rifa’I
Anti-Inflammatory And Insulin-Modulating Effects Of Tithonia-Curcuma-Moringa (Tcm) Formulation In Type 2 Diabetes: An Experimental Study In Mice, Rif’Atul Hawani Burhan, Nabila Shafa Yumna Salsabila, Devita Zulfa Pratama, La Tazkia Aulia Wibowo, Yulian Ervin Maulana, Moh Dliyauddin, Noviana Dwi Lestari, Agung Pramana Warih Marhendra, Aris Soewondo, Hideo Tsuboi, Muhaimin Rifa’I
Karbala International Journal of Modern Science
Type 2 diabetes is a chronic metabolic disorder characterized by hyperglycemia and chronic inflammation. This study investigated the anti-inflammatory and insulin-modulating effects of Tithonia-Curcuma-Moringa (TCM) formulation in type 2 diabetes model. Male BALB/c mice were divided into six groups: normal control, type 2 diabetes control, metformin treatment, and three TCM formulation treatment groups with three different dose combinations. Type 2 diabetes was induced using a high-fat diet combined with streptozotocin injection, supported by sucrose administration. After 21 days of treatment, the spleen and pancreas were isolated for flow cytometry analysis. The results showed that the expression levels of …