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Preparation Of Semi-Hard Cacciota Cheese From Local Milk And Analysis Of Its Physicochemical And Microbiological Properties, Shahnoza U. Yuldasheva, Dilshod P. Rakhimov, Dilrabo Q. Maksumova, Shahlo I. Akhmedova, Asaloy U. Narimonova

CHEMISTRY AND CHEMICAL ENGINEERING

Including cheese products in daily diet will give tangible results, enriching body with nutrients rich in high-quality proteins. The aim of the research is to create an Italian semi-hard cheese, caciotta, from local cow's milk. In the experiment, pepsin of the CHY-MAX® Powder Plus NB brand was used. The resulting product contained 1.46 mg/kg zinc (Zn), which is approximately 34 times lower than the permissible limit (50 mg/kg), which is considered a high quality indicator. From a biological safety point of view, no aflatoxin M1 was detected in the cheese (0.0 mg/kg), indicating the absence of mycotoxin contamination of cow's …

Effect Of Variety And Seaweed Extract Spray In The Content Of Some Medically Active Phenolic Compounds In Grape Fruits, Ali Ahmed Hussein Almyali, Salim Kadhim, Ali S. Hassoon, Ameer Al Fatlawy

Al-Bahir

Grape (Vitis vinifera L.) is one of the most economically significant fruit crops which has a large adaptive range, nutrition and medicine effect. A variety of 70 types of grapes are planted on more than 11.6 million plants in Iraq, generating a total annual output of more than 421,000 tons. Increasing grape quality, and particularly the phenolic composition recently has been of major interest. Leaf nutrition – particularly seaweed extracts, being rich in amino acids, trace elements and growth promoting substances – has proved to be a potential tool to enhance plant growth and fruit biochemical quality. The …

From Fair To Cure: Guidelines For Computational Models Of Biological Systems, Herbert M. Sauro, Eran Agmon, Michael L. Blinov, John H. Gennari, Joseph L. Hellerstein, Adel Heydarabadipour, Bartholomew E. Jardine, Elebeoba May, David P. Nickerson, Lucian P. Smith, Gary D. Bader, Frank T. Bergmann, Patrick M. Boyle, Andreas Dräger, James R. Faeder, Song Feng, Juliana Freire, Fabian Fröhlich, James A. Glazier, Thomas E. Gorochowski, Tomas Helikar, Henning Hermjakob, Stefan Hoops, Peter Hunter, Princess I. Imoukhuede, Sarah M. Keating, Matthias König, Reinhard Laubenbacher, Leslie M. Loew, Carlos F. Lopez, William W. Lytton, Rahuman S. Malik-Sheriff, Andrew Mcculloch, Pedro Mendes, Lealem Mulugeta, Chris J. Myers, Jerry G. Myers, Anna Niarakis, David D. Van Niekerk, Brett G. Olivier, Alexander A. Patrie, Ellen M. Quardokus, Nicole Radde, Johann M. Rohwer, Sven Sahle, James C. Schaff, Falk Schreiber, T. J. Sego, Janis Shin, Jacky L. Snoep, Rajanikanth Vadigepalli, H. Steven Wiley, Dagmar Waltemath, Ion I. Moraru

Computational Medicine Center Faculty Papers

Guidelines for managing scientific data have been established under the FAIR principles, requiring that data be Findable, Accessible, Interoperable, and Reusable. In many scientific disciplines, especially computational biology, both data and models are key to progress. For this reason, and recognizing that such models are a very special type of "data", we argue that computational models, especially mechanistic models prevalent in medicine, physiology and systems biology, deserve a complementary set of guidelines. We propose the CURE principles, emphasizing that models should be Credible, Understandable, Reproducible, and Extensible. We delve into each principle, discussing verification, validation, and uncertainty quantification for model …

3'Utr Mapping Reveals Alternative Polyadenylation In Right Ventricular Failure, Rahul Neupane, Kartiga Natarajan, Erik E Suarez, Henry J Pownall, Kai-Lieh Huang, Eric J Wagner, Ajay Kumar Verma, Rambabu Majji, Hari Krishna Yalamanchili, Ashrith Guha, Rajarajan A Thandavarayan

Children’s Nutrition Research Center Staff Publications

No abstract provided.

Assessing The Impact Of Lampenflora Growth On Invertebrate Distribution And Food Resource Use In Ryusen-Do Cave, Japan, Kazuhide Nakajima, Kanato Ando, Shuji Watanabe, Masuo Komukai

International Journal of Speleology

Subterranean spaces, such as caves with openings to the surface, represent unique environments characterized by limited resources derived from photosynthetic primary production. Consequently, organic inputs from organisms inhabiting above- and belowground habitats, such as bats, play a crucial role in maintaining cave ecosystems. However, in show caves converted into tourist attractions, environmental changes have progressed without sufficient ecological assessment. One important factor is the impact of photosynthetic organisms colonizing around artificial lights, known as lampenflora, on cave ecosystems. Lampenflora growth may influence invertebrate distribution and resource use; however, its impact on both aspects has been poorly evaluated. In this study, …

Comparative Effect Of Mineral, Organic, And Mixed Sunscreens Formulations On The Life History Of A Benthic Marine Invertebrate, Jacob Anthony Fox, Courtney Lott, Araceli Rodriguez-Romero, Gloria Massamba N'Siala

Knowledge and Creativity Expo

Mineral and organic sunscreens are emerging anthropogenic pollutants in coastal marine waters and have been shown to affect marine invertebrates via genotoxicity, endocrine disruption, oxidative stress, and impacts on life-history traits, such as reduced survival, growth, and fecundity. Most experiments expose marine organisms to isolated UV filters, with fewer studies testing complete formulations, co-occurring exposure to organic and mineral sunscreens, or the modulating influence of format type on toxicity. In this experiment, we tested the impact of organic sunscreens (3% Avobenzone, 15% Homosalate, 5% Octinoxate, and 10% Octocylene) and 24% zinc oxide mineral sunscreens on the survival and fecundity of …

Effects Of Alk2 Deficiency On T Cell Fate And Regulatory T Cell Populations, Jalyn Reeves, Afia Salsabil Alam

Knowledge and Creativity Expo

Regulatory T cells (Tregs) are central to immune tolerance, and their lineage stability is established during thymic development and maintained in the periphery through tightly regulated signaling networks. Members of the BMP receptor family have been implicated in T-cell differentiation, yet the specific role of the type I receptor ALK2 in shaping cell fate and sustaining the regulatory program remains unclear. To examine how ALK2 contributes to T-cell development, we generated ALK2-knockout murine chimeras and analyzed lymphoid populations from the thymus, spleen, and peripheral tissues. Thymocytes and lymphocytes were isolated and stained with antibody panels to identify developmental subsets and …

Interview With Orca Award Winner David Hage, Unl Chemistry; Drug-Protein Interactions, Mark Griep, David Hage

UNL ORCA Interview Series

Prof. David Hage was awarded the ORCA in 2018. He was born in La Crosse, Wisconsin, and earned a bachelor’s in chemistry at the University of Wisconsin in La Crosse. Next, he earned a doctorate from Iowa State University and did postdoctoral work at the Mayo Clinic in Rochester, Minnesota. In 1989, he joined UNL as an assistant professor of chemistry and quickly rose through the ranks. He has won many awards and, for the past 13 years, has been the James Hewet University Professor of Chemistry. Allow me to share some remarkable facts about Dave before we get into …

Variable Responses To Surface Washing Methods Used On Euplatypus Compositus (Curculionidae: Platypodinae) Prior To Fungal Isolation, Connor Biser, Jiri Hulcr, Miranda Barnes, Seth Bybee

Library/Life Sciences Undergraduate Poster Competition 2026

Ambrosia beetles (Platypodinae and Scolytinae) are a group of weevils that burrow into the xylem of trees and inoculate symbiotic fungi. These fungi grow in the walls of their galleries and serves as the beetles’ food source.1 [Fig. 1] This system of symbiotic interaction is highly convergent, and some beetles carry plant pathogens.2 Understanding the community of fungi associated with ambrosia beetles can help us assess forest risks and describe evolutionary patterns. When isolating fungi from beetles, researchers often include a preliminary surface washing step to limit superficial contaminants from the surface of the beetle. There have been no comparisons …

Unlikely Relationships: Plant Growth Promotion With Fish Waste Microbes, Thomas W. Scharf, Brad Geary

Library/Life Sciences Undergraduate Poster Competition 2026

1st Place - Open House Presentation

• Aiding plant growth is becoming more important as climate conditions continue changing in key wildlands and farmlands.
• Future Fresh Farms has created a product from fish waste, addressing this need.
• This study aimed to compare the outcomes of plants grown with MicroRevive, derived from fish waste, against plants grown with other growth promoting bacteria (PGPB).

Uncovering The Roles Of Environment And Phylogeny In The Expression Of A Shared Morphological Trait In Squamates, Austin Rejcek, Dylan Mcmullen, Logan Gren, Randy L. Klabacka

Library/Life Sciences Undergraduate Poster Competition 2026

Addressing the roles of adaptive and nonadaptive processes in trait evolution is a major focus of evolutionary biology

Recently, we observed an undescribed morphological trait on the eyelids of squamate lizards - AKA ''Palpebral combs'' (See photos)

This trait appears to be widespread within lguania, although there is consistent morphological variation between species of varying ecologies

The Role Of Nmda And Mglur5 Receptors On Hippocampal Depotentiation, J.H. Cummings, E. Sandberg, J.G. Edwards

Library/Life Sciences Undergraduate Poster Competition 2026

Depotentiation of LTP, the cellular mechanism of learning and memory, is thought to be the primary mechanism of forgetting.

Prior research in our lab investigated metabotropic glutamate receptor 5 (mGluR5) and its role in depotentiation and noted differences between males and females.

Preliminary data on NMDA receptors using AP5 (an antagonist) identified interesting findings, though n values are too low currently to draw conclusions.

Species Dynamics And Potential Invasion In The Restored Streams Of East Maui, Hannah Breinholt, Isabelle Hunter, Sarah Cole, Seth M. Bybee, Rachel L. Wood

Library/Life Sciences Undergraduate Poster Competition 2026

100+ years of water diversions in East Maui disrupted this connectivity, threatening native species and their habitat

In 2018, stream flow was restored to 22 streams

Endemic amphidromous fish in East Maui streams depend on intact flow from mountains to sea (mauka-to-makai) and are especially vulnerable to habitat disruption and isolation [1]

Has stream restoration enabled native fish species to recolonize or has it created openings for non-native species?

Shoot Apical Meristem Size And Inflorescence Morphology In Gilia, Madeleine Glover, Clinton Whipple

Library/Life Sciences Undergraduate Poster Competition 2026

Gilia, a genus of wildflower native to the western United States, is a promising new model for evolutionary developmental biology. Two closely related Gilia species, G. capitata and G. yorkii, are able to produce a fertile hybrid, though they differ in many morphological features, including inflorescence architecture. G. capitata has a tight capitate inflorescence with a high solitary flower number, while G. yorkii has a much more open inflorescence, with a solitary flower number of one. Analysis of shoot apical meristem (SAM) size in relationship with solitary flower number (SFN) will provide a deeper understanding of the evolution of this …

Self-Reported Longest-Held Occupation Type In Relation To Epilepsy In Late Life: A Pooled Cohort Analysis Of Incidence And Prevalence, Daniel Guerrero Gutierrez, Sofia Pelagalli Maia, Hyunmi Choi, Jose Gutierrez, Natalie Bello, Mary L. Biggs, Emily M. Briceño, James F. Burke, Lisandro D. Colantonio, Mitchell S.V. Elkind, Annette L. Fitzpatrick, Christopher Gonzalez, Alden L. Gross, Lei Huang, Emily L. Johnson, W. Craig Johnson, Cheng-Shiun Leu, Deborah A. Levine, Minghua Liu, W.T. Longstreth Jr., Richard P. Mayeux, Sylwia Misiewicz, Dolly Reyes-Dumeyer, Tatjana Rundek, Danurys Sanchez, Steven J. Shea, Tian Wang, Carolyn W. Shu, Evan L. Thacker

Library/Life Sciences Undergraduate Poster Competition 2026

Epilepsy in late life is influenced by biological, behavioral, social and environmental factors

Lifetime occupation type may capture socioeconomic, environmental, and long-term physical exposures relevant to brain health (e.g., manual labor, stress levels, neurotoxic exposures) that could influence neurological aging

Seizure Propagation And How Ketones May Help Mitigate Harmful Effects, Jacob Wassmer, Melissa L. Blotter, Isaac Stubbs, R. Ryley Parrish

Library/Life Sciences Undergraduate Poster Competition 2026

Status epilepticus (SE) is a seizure state characterized by continuous ictal activity lasting over 5 minutes. SE frequently becomes unresponsive to frontline antiepileptic drugs (AEDs), resulting in refractory status epilepticus (RSE), a neurological medical emergency with a mortality rate as high as 38% in some studies. To assess how SE develops over time, we have characterized an ex vivo brain slice SE model using a high-resolution multi-electrode recording system. The system contains over 4000 electrodes with less than 60μM of space in between each electrode. With this unprecedented spatial and temporal resolution, we have identified key features of SE that …

Research Process Toward The Creation Of Transgenic Beetles, Abraham B. Alton, Nathan Dauk, Jonah Jex, Brian D. Jensen, Sandra Hope

Library/Life Sciences Undergraduate Poster Competition 2026

Honorable Mention - Poster Design

Create a generalizable, reliable, and efficient procedure for insect genetic modification.

Insects born parasitic diseases such as malaria cause hundreds of millions of deaths each year. Many of these diseases could be eliminated if we had a reliable method for genetically modifying insects.

Potential Role Of Atr In Slower Aids Progression Associated With Hiv-1 Vpr Mutant R77q, Ava Wilstead, Sidney T. Sithole, Bradford K. Berges

Library/Life Sciences Undergraduate Poster Competition 2026

HIV-1 typically induces necrotic T cell death, resulting in chronic inflammation that drives Acquired Immunodeficiency Syndrome (AIDS) progression. However, mutations in viral protein R (Vpr) are associated with altered disease outcomes. The HIV-1 Vpr mutant R77Q is linked to individuals that do not progress to AIDS without treatment, termed a longterm non-progressor (LTNP). The Berges lab has shown that R77Q infection results in reduced overall cell death compared to wild-type (WT) virus, while inducing increased apoptotic cell death.

Muscle Transplants: Science Fiction Or Modern Medicine?, Erastus Evans, Mason Kephart, Benjamin Long, Jake Sorensen

Library/Life Sciences Undergraduate Poster Competition 2026

The loss of skeletal muscle from trauma or surgery results in limited regeneration and long-term dysfunction. Muscle transplants replenish lost cellular and structural tissue to improve healing and recovery of strength. Juvenile tissue offers a promising alternative to adult tissue due to the increased satellite cell and myofiber content.

Meta Analysis Of The Riverine Barrier Hypothesis In Mainland Southeast Asia, Gavin Kohl, Christian Furness, Eleanor Savage, Perry Van Wagoner, Randy Klabacka

Library/Life Sciences Undergraduate Poster Competition 2026

Understanding the drivers of biodiversification is an important objective in evolutionary biology

Yet much is still unknown regarding the mechanisms that drive biodiversity in species

Identifying barriers between lineages is a viable approach to discovering potential drivers

Iron Nutrition In Hydroponically Grown Quinoa, Ezra A. Larsen, Daniel L. Lamb, Shannon V. Nelson, Geneva M. Bell, Bryan G. Hopkins

Library/Life Sciences Undergraduate Poster Competition 2026

• Iron (Fe) deficiency is a global health challenge
• Fe is an essential plant nutrient and limiting factor for many food crops
• Quinoa (Chenopodium quinoa Willd.), a nutrient dense pseudocereal, is of growing importance for food security
• Quinoa is often grown in alkaline soil, where Fe is particularly limiting
• An improved understanding of how Fe affects quinoa growth could improve yields and help increase dietary iron intake

Investigating The Role Of Tnf In Hiv-1 Infected Cell Death, Brennan B. Wells, Sidney Sithole, Bradford Berges

Library/Life Sciences Undergraduate Poster Competition 2026

HIV-1 is the causative agent of the terminal disease AIDS. Clinical studies have determined that patients infected with a mutant of HIV-1, Vpr-R77Q, do not progress towards AIDS. Subsequently, our lab has discovered two notable differences between the Vpr- R77Q variant and WT HIV-1: increased levels of apoptosis in infected cells (which is thought to contribute to the lack of AIDS progression), and decreased levels of inflammatory cytokines, namely Tumor Necrosis Factor (TNF). The purpose of this ongoing experiment is to investigate the potential inverse correlation between TNF levels and apoptosis levels through the introduction of additional TNF cytokines to …

Investigating The Mechanisms Of Yersinia Ruckeri Inhibition By A New Strain Of Pseudomonas Fjordensis, Kyler Linton, David Erickson

Library/Life Sciences Undergraduate Poster Competition 2026

Pacific freshwater fish are less likely than Atlantic freshwater fish to exhibit Enteric Redmouth Disease (ERM), or Yersiniosis as caused by Yersinia ruckeri. Based on the hypothesis that these fish may harbor commensal bacteria that inhibit Y. ruckeri growth, I isolated many kinds of commensal bacteria from fish intestines collected from Alaska and local streams. In previous studies, I have isolated novel bacteria capable of expressing inhibitory activity against Y. ruckeri via co-culture experiments. One of these bacteria is a strain of Pseudomonas fjordensis. Through genome-wide mutagenesis techniques, a possible gene has been unveiled that may be contributing to this …

Interactive Effects Of Salinity And Glyphosate On Wetland Soil Microbial Communities, Ryan Mortensen, Madison Brown, Rachel Wood

Library/Life Sciences Undergraduate Poster Competition 2026

Wetland soil microbes play an important role in maintaining ecosystem health by cycling nutrients, breaking down organic matter, and maintaining water quality. Herbicide exposure has been shown to alter the genetic composition and functional potential of soil microbial communities, including shifts in microbial nutrient cycling processes [1].

Two of the most prominent environmental stressors in Utah’s wetlands are excessive salinity and herbicide exposure. Increased salinity can change how herbicides move and persist in water, which may influence their ecological effects [2]. While each stressor has been studied independently, little is known about their combined effects on soil microbial community structure …

In Silico Studies Of Hiv-1 Vpr R77q Mutant’S Structure And Stability, Linnea Mason, Sidney T. Sithole, Bradford K. Berges

Library/Life Sciences Undergraduate Poster Competition 2026

Human immunodeficiency virus type 1 (HIV-1) is a retrovirus that infects CD4+ T cells. Without treatment, infection with HIV-1 usually leads to acquired immunodeficiency syndrome (AIDS), which is characterized as severe immunosuppression (CD4+ count: < 200cells/mm3 of blood). However, some individuals do not advance to AIDS and are known as long-term non-progressors (LTNP). Interestingly, a small viral protein of HIV-1, called viral protein R (Vpr), has been associated with HIV-1 progression. The R77Q mutant has been linked to the LTNP phenotype and increased levels of apoptosis; however, the mechanisms behind it are not yet understood [1]. Previously, our group has found that Vpr was expressed at lower levels in cells infected with R77Q virus compared to the wildtype (WT) virus by western blot [1]. Image quantification of the bands showed an approximate six-fold reduction in protein levels.

Genetic And Morphological Comparison Between Introduced And Native Populations Of Aspidocelis Neomexicanus, Sadie Hale, Jordan Kirk, Arianna Moore, Perry Van Wagoner, Vicente Fernández Lara, Angelina Romero, Dallin Matthews, Álvaro Osuna Jiménez, Reagan Mckee, Randy Klabacka

Library/Life Sciences Undergraduate Poster Competition 2026

The introduction of non-native species to novel ecosystems can have negative impacts on the environment, economy, and human health.

Understanding the processes driving patterns in dispersion, establishment, and expansion of introduced species can illuminate strategies to reduce the occurrence of introduction and mitigate its effects.

The New Mexico Whiptail (Aspidoscelis neomexicanus) is a parthenogenetic (asexually-reproducing) species of lizard in the family Teiidae.

Exploring The Impact Of Redox Perturbations On Optic Tectum Development And Behavior, Kevin Gray, Bailey Calder, Daniel Andersen, Parker Hamblin, Michael Zeyer, Arminda Suli

Library/Life Sciences Undergraduate Poster Competition 2026

The optic tectum (OT), the non-mammalian counterpart of the mammalian superior colliculus (SC), integrates multisensory information and orchestrates behavioral responses such as reflexive movements and attention shifts. It is localized in the midbrain, where anterior-posterior patterning is regulated by transcription factors dependent on proper endogenous H2O2 levels. Recent studies have implicated the OT/SC and early redox imbalance in neurodevelopmental disorders such as autism spectrum disorder (ASD). Given the importance of H2O2 in midbrain development, we are investigating how redox perturbations may lead to atypical OT circuitry development and, subsequently, result in aberrant behavioral phenotypes, similar to those associated with ASD. …

Enhancing Metabolic Fitness Of Car T-Cells By Removing Cd6, Nate Neyman, Alka Guar, Annie Joy-Larson, Collin Mickelson, Scott Weber

Library/Life Sciences Undergraduate Poster Competition 2026

Honorable Mention - Poster Design

CAR T-cell therapy is a highly effective cancer treatment involving engineering the patient’s T-cells to recognize and kill cancerous cells. This therapy has shown great success for blood cancers but has faced many challenges against solid tumors.

Surrounding tumor cells there is a lack of essential nutrients (oxygen, glucose) for T-cells to metabolize efficiency. Additionally, there is a buildup of excess waste products that directly impair T-cell function (1). To overcome these obstacles, scientists are working on developing longer lasting T-cells with improved metabolism to improve efficacy against cancer cells.

The Story Behind The Waves: Effects Of Urbanization And Female Presence On Waving Behavior In Fiddler Crabs, Katelyn Hansen, Blaine Griffen

Library/Life Sciences Undergraduate Poster Competition 2026

Animal communication plays a central role in survival and reproduction, allowing individuals to convey information about their quality, territory, and reproductive statuses. Because signaling behaviors are often energetically costly and are dependent on both social contexts and habitat, they are sensitive to environmental conditions. Previous research has shown that male sand fiddler crabs (Leptuca pugilator) produce two distinct wave types: D-waves (typically directed towards other males) and up-and-down waves (typically directed toward females), and that they also reduce their waving behavior under urban stress. Urbanization introduces stressors such as habitat alteration and increased disturbances that can change the frequency and …

Discovery Of Short Antimicrobial Peptides In A Periplasmic Expression System, Joel Griffitts, Adam Dunn, Caleb Parker, Matthew Steed

Library/Life Sciences Undergraduate Poster Competition 2026

Short Antimicrobial peptides (sAMPs) have the potential to make a significant impact in the ongoing battle against antibiotic-resistant bacteria. In this project, we aim to discover new sAMPs using a novel peptide expression system in E. coli. Using this system, we have successfully identified various sAMPs by testing both rationally designed peptides and randomized peptide libraries.