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Sport And Environmental Issues: Ncaa Division I Student-Athletes’ Personal Experiences, Ivanna M. Anderson-Villela Aug 2024

Sport And Environmental Issues: Ncaa Division I Student-Athletes’ Personal Experiences, Ivanna M. Anderson-Villela

Master's Theses

While sport ecology is a growing category in sport management literature, there is a lack of research exploring athletes’ experiences regarding environmental issues, and the impacts environmental issues have on student-athletes. The present study qualitatively explored the personal lived experiences of eight NCAA Division I student-athletes regarding environmental issues with the aim of identifying potential influences on values and beliefs through social norms and understanding the student-athlete perspective. Thematic analysis identified 152 raw data themes and 19 higher order themes, which were organized into four central themes: awareness, care and concern from athletic departments, implications, and advocacy. Generally, student-athletes perceived …


Five A Day, The Rainbow Way: A Nutrition Education Toolkit For Elementary School Aged Children, Sasha Menard Aug 2024

Five A Day, The Rainbow Way: A Nutrition Education Toolkit For Elementary School Aged Children, Sasha Menard

Department of Nutrition Student Projects

Learning Outcome: Develop a nutrition educational toolkit based on Social Cognitive Theory (SCT) for obesity prevention among elementary school-aged children by improving determinants of fruit and vegetable intake.

Background: Poor consumption of fruits and vegetables is a major contributing factor to childhood obesity, increasing the risk for chronic diseases later in life. There is a need for multicomponent nutrition educational tools to influence children to improve their eating behavior by increasing their awareness and self-efficacy. The current project describes the development of a 3-component toolkit for improving participants’ knowledge and values related to fruit and vegetable intake among 6-11-year-olds.

Methods: …


The Prevalence Of Stress Fractures And The Associated Leaf-Q Responses, Self-Reported Exercise Volume And Dietary Behaviors In Female Recreational Runners, Malorie Wilwand, Kelly Pritchett, Marissa Miles, Robert Pritchett, Abigail Larson Aug 2024

The Prevalence Of Stress Fractures And The Associated Leaf-Q Responses, Self-Reported Exercise Volume And Dietary Behaviors In Female Recreational Runners, Malorie Wilwand, Kelly Pritchett, Marissa Miles, Robert Pritchett, Abigail Larson

International Journal of Exercise Science

International Journal of Exercise Science 17(2): 1092-1104, 2024. Previous research suggests a high prevalence of low energy availability (LEA) and stress fractures (SF) among competitive female endurance athletes. However, much less is known about these issues among recreational female runners. This study aimed to assess the prevalence and number of self-reported SF and risk of LEA among noncompetitive, recreationally active female runners, aged 18 – 25 years. Additionally, it compared characteristics between females with a history of multiple SF vs. one or no SF, and between those ‘at risk’ vs. ‘not at risk’ of LEA. Female recreational runners (n=485) completed …


The Cadet Athlete Physical Training Intervention (Capti): A 16-Week Periodized Program To Remediate Underdeveloped Tactical Athletes At A Senior Military College, Margaret T. Thornton, Amy S. Welch, Scott Caulfield, Rachele M. Pojednic Aug 2024

The Cadet Athlete Physical Training Intervention (Capti): A 16-Week Periodized Program To Remediate Underdeveloped Tactical Athletes At A Senior Military College, Margaret T. Thornton, Amy S. Welch, Scott Caulfield, Rachele M. Pojednic

International Journal of Exercise Science

International Journal of Exercise Science 17(4): 1083-1091, 2024. Approximately half of military recruits fail the Army Physical Fitness Test (APFT), and 70% of all injuries in the US military are musculoskeletal in nature. The purpose of this study was to investigate whether underdeveloped musculoskeletal and cardiovascular fitness levels and subsequent APFT scores of senior military college cadets could be improved by a novel, evidence-based Cadet Athlete Physical Training Intervention (CAPTI) compared to the current Remedial Physical Training program (RPT). Cadets failing the APFT (total score < 180, or < 60 in scored sit-ups, pushups or run time, respectively) participated in a 16-week remedial training program including either CAPTI (periodized full body calisthenic and varied-technique cardiovascular training, along with mobility training and mental health and wellbeing sessions), or a traditional, event-specific remedial training program (RPT). CAPTI was randomly assigned to one of three battalions, while the others received RPT. One hundred and thirty-eight cadets (n = 70 CAPTI, n = 68 RPT) participated in the study. After training, 82.9% …


Friend Social Network Size Moderates The Association Between Age And Physical Activity Across Adulthood, Ashley Kuzmik, Yin Liu, Yendelela Cuffee, Lan Kong, Christopher N. Sciamanna, Liza S. Rovniak Aug 2024

Friend Social Network Size Moderates The Association Between Age And Physical Activity Across Adulthood, Ashley Kuzmik, Yin Liu, Yendelela Cuffee, Lan Kong, Christopher N. Sciamanna, Liza S. Rovniak

International Journal of Exercise Science

International Journal of Exercise Science 17(5): 1068-1082, 2024. Both physical activity and social network size decline as people age. However, limited research has examined if social network size and contact frequency differentially influence physical activity across the adult lifespan. This study aimed to assess if these social network characteristics moderated the relationship between age and physical activity level across adulthood. Multiple regression analyses were conducted to examine the main-effect association between age, past-week physical activity, and past-year physical activity, as well as the moderating effect of social network characteristics (i.e., friend network size, friend contact frequency, relative network size, and …


Disability In Cluster Headache Is More Than Attack Frequency – Results From And Validation Of The English Version Of The Cluster Headache Impact Questionnaire (Chiq), Katharina Kamm, Andreas Straube, Mark Burish, Ruth Ruscheweyh Aug 2024

Disability In Cluster Headache Is More Than Attack Frequency – Results From And Validation Of The English Version Of The Cluster Headache Impact Questionnaire (Chiq), Katharina Kamm, Andreas Straube, Mark Burish, Ruth Ruscheweyh

Faculty, Staff and Student Publications

BACKGROUND: Cluster headache (CH) is associated with high disability. The Cluster Headache Impact Questionnaire (CHIQ) is a short, disease-specific disability questionnaire first developed and validated in German. Here, we validated the English version of this questionnaire.

METHODS: The CHIQ was assessed together with nonspecific headache-related disability questionnaires in CH patients from a tertiary headache center and an American self-help group.

RESULTS: 155 active episodic and chronic CH patients were included. The CHIQ showed good internal consistency (Cronbach's α = 0.91) and test-retest reliability (ICC = 0.93, n = 44). Factor analysis identified a single factor. Convergent validity was shown by …


Acceptability Of Heart Rate-Based Remote Monitoring Of Smoking Status., Matthew Mitnick, Shelby Goodwin, Mikaela Bubna, Justin S White, Bethany Raiff Aug 2024

Acceptability Of Heart Rate-Based Remote Monitoring Of Smoking Status., Matthew Mitnick, Shelby Goodwin, Mikaela Bubna, Justin S White, Bethany Raiff

College of Science & Mathematics Departmental Research

INTRODUCTION: Digital interventions present a scalable solution to overcome barriers to smoking cessation treatment, and changes in resting heart rate (HR) may offer a viable option for monitoring smoking status remotely. The goal of this study was to explore the acceptability of using smartphone cameras and activity trackers to measure heart rate for use in a smoking cessation intervention.

METHODS: Participants (N=410), most of whom identified as female (75.8 %) with mean age 38.3 years (SD 11.4), were recruited via the Smoke Free app. They rated the perceived comfort, convenience, and likelihood of using smartphone cameras and wrist-worn devices for …


A Qualitative Description Of Graduate Students’ Perceived Decline In Physical Activity From Undergraduate School, Kristin M. Jett, Bryce T. Daniels, Max Brigance, Jessica L. Passarelli, Erin Howie Aug 2024

A Qualitative Description Of Graduate Students’ Perceived Decline In Physical Activity From Undergraduate School, Kristin M. Jett, Bryce T. Daniels, Max Brigance, Jessica L. Passarelli, Erin Howie

International Journal of Exercise Science

International Journal of Exercise Science 17(5): 1038-1055, 2024. Many university students, especially graduate students, are experiencing poor physical and psychological health. Thus, universities are initiating programs like Exercise is Medicine-On Campus (EIM-OC) to promote positive physical activity behavior to improve physical and mental health for primarily undergraduate university students. However, the influences on physical activity when transitioning from an undergraduate to a graduate student are unknown. To explore perceptions of if and how the physical activity levels of graduate students changed from their time as undergraduate students while considering environmental and lifestyle factors. METHODS: Using a qualitative, phenomenological research design, …


Investigating The Effects Of Visual Feedback On Muscle Activity, Heart Rate, Rpe, And Perceptions Of Performance In Ballet Dancers, Lilah A. Duboff, Sarah Dipasquale, Stephen Ives Aug 2024

Investigating The Effects Of Visual Feedback On Muscle Activity, Heart Rate, Rpe, And Perceptions Of Performance In Ballet Dancers, Lilah A. Duboff, Sarah Dipasquale, Stephen Ives

International Journal of Exercise Science

International Journal of Exercise Science 17(1): 1056-1067, 2024. Extreme postures and imbalances in neuromuscular activity may place classical ballet dancers at higher risk of injury. Dance studio mirrors provide visual feedback by which a dancer can self-correct their body position and alignment, but have been suggested to negatively impact kinesthetic abilities and decrease performance capabilities. Thus, we investigated the effects of a mirror on muscle activity of the quadriceps, heart rate (HR), rating of perceived exertion (RPE), and qualitative performance. A lack of visual feedback would increase muscle activity of the quadriceps, HR, and RPE, and decrease self-reported perception of …


The Effects Of People, Time Of Day, And Season On Affiliative And Stereotypic Behaviors In Captive Rhinoptera Bonasus And Other Rays Across Two Human-Interactive Enclosures, Wren C. A. Newman Aug 2024

The Effects Of People, Time Of Day, And Season On Affiliative And Stereotypic Behaviors In Captive Rhinoptera Bonasus And Other Rays Across Two Human-Interactive Enclosures, Wren C. A. Newman

Theses and Dissertations

Cownose rays (Rhinoptera bonasus) are among the most common species found in aquaria, yet the impact of touch enclosures on their welfare remains largely unknown. While research on animal-visitor interactions has produced mixed results for other species, the lack of studies focusing on fish welfare poses a risk of overlooking potential welfare concerns. Therefore, we aimed to establish a baseline for cownose rays regarding stereotypic behaviors, sociality, and activity in captivity, and to examine the influence of human interaction on these behaviors. We collected over 700 hours of footage from two enclosures at Adventure Aquarium in Camden, NJ …


Sex Differences In The Diets Of Forest-Dwelling Baboons (Papio Anubis), Kara Hartunian Aug 2024

Sex Differences In The Diets Of Forest-Dwelling Baboons (Papio Anubis), Kara Hartunian

Theses and Dissertations

The ability to eat and switch between many food sources is an adaptative feeding strategy utilized for meeting nutritional needs across different environments, seasons, and physiological conditions. Baboons (genus Papio) excel at both dietary flexibility and foraging selectively, and consequently have one of the most widespread geographic distributions in the Order. To further expand to our understanding of baboon feeding ecology, I analyzed foraging activity and the nutritional characteristics of the diets of the relatively understudied rainforest baboons (Papio anubis) living in Kibale National Park, Uganda. I also investigated if there are differences in food type choice …


Maternal And Other Social Influences On Signature Whistle Structure Of A Captive Group Of Bottlenose Dolphins (Tursiops Truncatus), Riley Synan Aug 2024

Maternal And Other Social Influences On Signature Whistle Structure Of A Captive Group Of Bottlenose Dolphins (Tursiops Truncatus), Riley Synan

Theses and Dissertations

Bottlenose dolphins (Tursiops truncatus) are social animals that use acoustics as a major method of communicating across a marine environment. They also live in fission-fusion groups and thus interact with many conspecifics over a lifetime. Individual dolphins have a signature whistle that functions as an identity call and serves to maintain group cohesion in murky waters or during reconciliation. Dolphins exhibit vocal learning and the signature whistle of a calf may be modeled after the whistle of their mother or another individual in the pod as they develop. Mother-calf pairs or other related animals sometimes have similar whistle types. Some …


Assessing Comprehension And Competence In Bottlenose Dolphins (Tursiops Truncatus) On The Concept: Do Something Different, Charlotte M. Mulligan Aug 2024

Assessing Comprehension And Competence In Bottlenose Dolphins (Tursiops Truncatus) On The Concept: Do Something Different, Charlotte M. Mulligan

Theses and Dissertations

Many studies have been conducted using a training paradigm based on the research of Pryor et al. (1969) wherein the participants are trained on the abstract concept: do something different. This paradigm challenges working memory and requires the participants to respond with a behavior, either previously trained or novel, which has not yet been offered within the session. The work of Braslau-Schneck (1994) expanded this concept and demonstrated the ability of dolphins to successfully complete this task in synchronized pairs, though the method of accomplishing this task remained unclear. The present research was conducted as part of a broader …


Covid-19 Prevention Behaviors And Dietary Habits Among Undergraduate Students: A Health Belief Model Approach, Doreen Liou Aug 2024

Covid-19 Prevention Behaviors And Dietary Habits Among Undergraduate Students: A Health Belief Model Approach, Doreen Liou

Department of Nutrition and Food Studies Scholarship and Creative Works

Physical and social disruptions resulted from the COVID-19 pandemic, affecting young adults in higher education. The purpose of this survey research is to unveil COVID-19 related beliefs using the Health Belief Model, and COVID-19 prevention behaviors, including self-reported fruit and vegetable consumption among university students. A cross-sectional survey was administered to 304 male and female undergraduate students from diverse ethnic backgrounds and majors at a New Jersey state university using convenience sampling. Variables measured included frequency of COVID-19 prevention behaviors (e.g.: wearing indoor mask, handwashing), and consumption of fruit and vegetables (dark green and orange vegetables) over the previous week. …


Shifting Paradigms In Recreation Management: Applying Social-Ecological System Frameworks To Parks And Protected Areas, Noah Creany Aug 2024

Shifting Paradigms In Recreation Management: Applying Social-Ecological System Frameworks To Parks And Protected Areas, Noah Creany

All Graduate Theses and Dissertations, Fall 2023 to Present

Park and protected area (PPA) recreation management is often characterized by social, ecological, and managerial dimensions. These dimensions have increasingly been conceptualized as social-ecological systems (SESs) to understand the complex interrelationships between them. Contemporary trends of increased visitation on public lands in the United States, including US National Parks, have accentuated the complex interactions between the amount of recreation use, the capacity of the setting, the quality of the visitor experience, and ecological resource conditions. These challenges of managing recreation use and understanding these interactions will be further compounded by climate change and its effects on ecosystem composition and dynamics. …


Emotional Eating In Adolescents With Obesity: Case Series, Paula Dayan Aug 2024

Emotional Eating In Adolescents With Obesity: Case Series, Paula Dayan

Electronic Theses, Projects, and Dissertations

Childhood obesity remains a significant public health concern, with substantial implications for physical and mental well-being. This thesis aims to explore the intricate relationship between emotional eating and obesity among adolescents, with a focus on identifying emotional triggers and assessing their psychological impact. Utilizing a cross-sectional study design at a university in southern California, data were collected from two adolescents aged 13-18 years. Through surveys and body composition measurements, participants' emotional barriers to weight loss and readiness for change were assessed. The findings underscore the presence of varying degrees of emotional hurdles among adolescents with obesity, including depression, frustration, and …


Application Of Criminology In Urban Ecology And Evolution: Routine Activity Theory And Field Equipment Disappearance Dynamics, Ignacy Stadnicki, Michela Corsini, Marta Szulkin Aug 2024

Application Of Criminology In Urban Ecology And Evolution: Routine Activity Theory And Field Equipment Disappearance Dynamics, Ignacy Stadnicki, Michela Corsini, Marta Szulkin

Biology Faculty Publications and Presentations

Research in urban ecology and evolution relies on the use of deployable scientific equipment. If left unattended in the field, scientific equipment may be prone to vandalism and theft, especially in the urban space. Here, we empirically applied a theory derived from the field of criminology, specifically the Routine Activity Theory (RAT) framework, to predict disappearance rates of scientific equipment in an ongoing urban ecology research project. First, we tested a routinely applied method of equipment protection – labelling – and investigated whether equipment disappearance varied with label information content and message tone. Second, we examined whether equipment attributes (price, …


Using Wasp Specimens In Taxonomic, Biogeographic, Evolution, And Informal Education Studies, Brenna Lynn Decker Aug 2024

Using Wasp Specimens In Taxonomic, Biogeographic, Evolution, And Informal Education Studies, Brenna Lynn Decker

All Graduate Theses and Dissertations, Fall 2023 to Present

Entomology collections hold an untapped wealth of information, from insect morphology, genetics, locality and association data, and potential for use in education. Especially with insects that generate initial fears, such as wasps, seeing insect specimens provides a safe environment to learn about their behaviors. Wasps are insects in the order Hymenoptera, along with ants and bees. The public may hold fears against wasps, due to their negative portrayal in various media, but they serve as integral components of a functional ecosystem. Even with their importance, many groups of wasps are still highly understudies. This dissertation aims to tackle this fear …


Evaluation Of Subjective And Objective Workload Of Forestry Professionals, Hasini L. M. Mapatunage Aug 2024

Evaluation Of Subjective And Objective Workload Of Forestry Professionals, Hasini L. M. Mapatunage

All Theses

The Southern United States accounts for about 40% of the productive timberland of the country and is known as the wood basket of the United States. Timber logging is an important contributor to South Carolina’s economy. Feller-buncher, skidder and loader operators play a vital role in the timber industry of South Carolina. However, their job is far from easy, especially as there are only a few members of a logging crew. They have to operate complex heavy machinery in challenging terrains while ensuring the efficient harvesting of timber, which demands extraordinary skills, precision, and better decision-making, leading to excessive mental …


Quantifying Physical Function: Moving Towards A New Definition And Better Assessment, Anthony Campitelli Aug 2024

Quantifying Physical Function: Moving Towards A New Definition And Better Assessment, Anthony Campitelli

Graduate Theses and Dissertations

Though poor physical function (PF) and disability are two of the most impactful problems facing older adults today, the field of kinesiology has not yet devised a method of measuring PF, thus limiting investigations with the potential to lead to improved PF interventions and assessments. This dissertation aimed to develop a single, continuous measure of PF using a latent variable modeling approach, and then use the generated scores to evaluate the role of lower body muscular power in PF assessment and to construct an improved PF assessment battery for predicting overall PF. Each aim of this dissertation was addressed through …


The Effects Of Anchor Scheme On The Central And Peripheral Contributions To Performance Fatigability, Perceived Responses And Sensations, And Psychological Factors Following Sustained, Isometric Forearm Flexion Tasks To Failure, Robert Walker Smith Aug 2024

The Effects Of Anchor Scheme On The Central And Peripheral Contributions To Performance Fatigability, Perceived Responses And Sensations, And Psychological Factors Following Sustained, Isometric Forearm Flexion Tasks To Failure, Robert Walker Smith

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

The Effects of Anchor Scheme on the Central and Peripheral Contributions to Performance Fatigability, Perceived Responses and Sensations, and Psychological Factors Following Sustained, Isometric Forearm Flexion Tasks to Failure Robert W. Smith, Ph.D. University of Nebraska, 2024 Advisor: Terry J. Housh This study assessed time to task failure (TTF), performance fatigability (PF), neuromuscular responses, central and peripheral measures of fatigue, and perceived responses including sensations and psychological factors that contributed to task termination during sustained, isometric forearm flexion tasks anchored to ratings of perceived exertion (RPE) and the torque corresponding to RPE. Fifteen men (age = 21.5 ± 2.3 yrs; …


Atypical Brain Aging And Its Association With Working Memory Performance In Major Depressive Disorder, Natalie C.W. Ho, Richard A.I. Bethlehem, Jakob Seidlitz, Nikita Nogovitsyn, Paul Metzak, Pedro L. Ballester, Stefanie Hassel, Susan Rotzinger, Jordan Poppenk, John Blangero Aug 2024

Atypical Brain Aging And Its Association With Working Memory Performance In Major Depressive Disorder, Natalie C.W. Ho, Richard A.I. Bethlehem, Jakob Seidlitz, Nikita Nogovitsyn, Paul Metzak, Pedro L. Ballester, Stefanie Hassel, Susan Rotzinger, Jordan Poppenk, John Blangero

Human Genetics Publications

Background: Patients with major depressive disorder (MDD) can present with altered brain structure and deficits in cognitive function similar to those seen in aging. However, the interaction between age-related brain changes and brain development in MDD remains understudied. In a cohort of adolescents and adults with and without MDD, we assessed brain aging differences and associations through a newly developed tool that quantifies normative neurodevelopmental trajectories. Methods: A total of 304 participants with MDD and 236 control participants without depression were recruited and scanned from 3 studies under the Canadian Biomarker Integration Network for Depression. Volumetric data were used to …


An Examination Of The Impact Of College Health And Wellness Courses On Mental Health – Two Paper Format: A Literature Review And A Comparison Of The Impact Of Two College Health And Wellness Courses On Affect, Perceived Stress, And Cognitive Distortions, Robin Phipps Woodall Aug 2024

An Examination Of The Impact Of College Health And Wellness Courses On Mental Health – Two Paper Format: A Literature Review And A Comparison Of The Impact Of Two College Health And Wellness Courses On Affect, Perceived Stress, And Cognitive Distortions, Robin Phipps Woodall

Boise State University Theses and Dissertations

Objective: To compare the impact of two 15-week health and wellness courses on mental health measures in college students. Participants: College student volunteers were recruited after enrolling in one of two 15-week health and wellness courses. Methods: The control course (N=19) had an ethical emphasis, and the experimental course (N=21) had a cognitive behavioral emphasis. Participants completed a demographic questionnaire and pre- and post-tests of the Perceived Stress Scale, the Positive and Negative Affect Schedule-General Form, and the Cognitive Distortion Questionnaire. Pre- to Post-Changes were analyzed using a mixed model repeated measures ANOVA between the two courses. Results: Both courses …


Measurement Reliability For Intentions To Change Behavior, Emily Schlichtig Aug 2024

Measurement Reliability For Intentions To Change Behavior, Emily Schlichtig

Graduate Theses and Dissertations

It is common for researchers to ask participants to associate probabilities with words, often using tools like the Likert scale to measure behavioral intentions and attitudes. However, it remains unclear what specific probabilities participants assign to the response options on a Likert scale, how much variation exists across these options, and whether these probabilities differ across various behaviors. The purpose of this paper is to explore the numeric probabilities that participants associate with different Likert scale points, to understand their perception of the variation at each point, and to compare these perceptions across three behaviors: eating more vegetables, exercising more, …


Enriching The Pcos Lifestyle, Callie Coleman Aug 2024

Enriching The Pcos Lifestyle, Callie Coleman

Electronic Theses and Dissertations

Polycystic Ovary Syndrome (PCOS) is an endocrine disorder affecting approximately 4 – 20% of women worldwide. It is associated with insulin resistance, fertility problems, and an increased susceptibility to chronic conditions through multiple inflammatory pathways. Women with PCOS are also at increased risk for disordered eating. The Mediterranean diet is associated with decreased inflammation and risk of chronic conditions, and intuitive eating principles are associated with decreased disordered eating patterns. The purpose of this study was to determine if a six-week nutrition education workshop incorporating information and skills related to both the Mediterranean lifestyle and intuitive eating principles can improve …


The Effects Of An Acute Dose Of Cannabidiol On Health And Two-Mile Time Trial Performance, Elyssa Bell Aug 2024

The Effects Of An Acute Dose Of Cannabidiol On Health And Two-Mile Time Trial Performance, Elyssa Bell

Master's Theses

As more studies exploring the therapeutic effects of cannabidiol (CBD) in both clinical and non-clinical populations continue to increase, there is a renewed interest in the ability of CBD to affect performance. In fact, many anecdotal reports in the media and online suggest that CBD may improve performance. Unfortunately, very few studies support these claims and research in the area is limited. Purpose: The purpose of this study is to explore the effects of an acute dose of CBD on anxiety symptoms, GI distress, heart rate variability (HRV), heart rate (HR), blood pressure (BP), blood lactate (BL) rate of perceived …


Effects Of Increasing Cycling Cadence On Post-Cycling Gait Velocity: An Experimental Study, Nitu Lama Aug 2024

Effects Of Increasing Cycling Cadence On Post-Cycling Gait Velocity: An Experimental Study, Nitu Lama

Master's Theses

Previous research has shown that increasing cycling cadence, rather than the workrate, can result in improved post-cycling gait velocity. However, the specific threshold of cycling cadence required to bring about clinically meaningful changes in gait velocity remains unknown. To address this knowledge gap, our study aimed to determine the minimum incremental increase in cycling cadence that would lead to a significant improvement in post-cycling gait velocity. A total of 42 young adults participated in our study and were randomly assigned to one of three groups: TEN, TWENTY, and THIRTY. Each group was assigned to cycle at a cadence at the …


The Role Of The Circadian Clock In The Paraventricular Nucleus Of The Hypothalamus In Diurnal Energy Balance, Rachel Van Drunen Aug 2024

The Role Of The Circadian Clock In The Paraventricular Nucleus Of The Hypothalamus In Diurnal Energy Balance, Rachel Van Drunen

Dissertations and Theses (Open Access)

Circadian rhythms are internal biological rhythms that drive oscillations in physiology and metabolism. Maintained at the level of individual cells throughout the body, the circadian clock is necessary for driving tissue-specific temporal programs of energy balance. Though loss of the circadian transcription factor, BMAL1, in the paraventricular nucleus (PVN) of the hypothalamus has revealed its importance in driving rhythms in energy intake and metabolism, its transcriptional functions across time and in individual cell types in the PVN are not well understood. In this study, we show that loss of BMAL1 in the PVN not only results in arrhythmicity in processes …


The Influence Of Oxidative Stress On Ion Homeostasis And Glycolysis Activation, With Implications For Neurological Health And Multiple Sclerosis, Xavier Hayes Aug 2024

The Influence Of Oxidative Stress On Ion Homeostasis And Glycolysis Activation, With Implications For Neurological Health And Multiple Sclerosis, Xavier Hayes

Graduate Student Dissertations, Theses, Capstones, and Portfolios

Multiple sclerosis (MS) is a neurodegenerative disease in which the body’s immune system attacks its own tissues, notably the neural cells, and one of the contributing factors to this is oxidative stress. Oxidative stress is the build-up of reactive oxygen species ROS that causes oxidative damage to the cells. Chronic and environmental stressors are explored as significant factors that exacerbate these conditions by disrupting cellular processes and energy metabolism. The paper reviews current literature on MS, examining the interplay between oxidative stress, environmental factors, and genetic predispositions. Additionally, it discusses how these factors contribute to MS, where the immune system …


Cerebrovascular Reactivity Mri As A Biomarker For Cerebral Small Vessel Disease–Related Cognitive Decline: Multi-Site Validation In The Markvcid Consortium, Peiying Liu, Zixuan Lin, Kaisha Hazel, George Pottanat, Cuimei Xu, Dengrong Jiang, Jay J. Pillai, Emma Lucke, Christopher E. Bauer, Brian T. Gold, Steven M. Greenburg, Karl G. Helmer, Kay Jann, Gregory Jicha, Joel Kramer, Pauline Maillard, Rachel M. Mulavelil, Pavel Rodriguez, Claudia L. Satizabal, Kristin Schwab, Sudha Seshadri, Herpreet Singh, Ángel G. Velarde Dediós, Danny J. J. Wang, Rita R. Kalyani, Abhay Moghekar, Paul B. Rosenberg, Sevil Yasar, Marilyn Albert, Hanzhang Lu Aug 2024

Cerebrovascular Reactivity Mri As A Biomarker For Cerebral Small Vessel Disease–Related Cognitive Decline: Multi-Site Validation In The Markvcid Consortium, Peiying Liu, Zixuan Lin, Kaisha Hazel, George Pottanat, Cuimei Xu, Dengrong Jiang, Jay J. Pillai, Emma Lucke, Christopher E. Bauer, Brian T. Gold, Steven M. Greenburg, Karl G. Helmer, Kay Jann, Gregory Jicha, Joel Kramer, Pauline Maillard, Rachel M. Mulavelil, Pavel Rodriguez, Claudia L. Satizabal, Kristin Schwab, Sudha Seshadri, Herpreet Singh, Ángel G. Velarde Dediós, Danny J. J. Wang, Rita R. Kalyani, Abhay Moghekar, Paul B. Rosenberg, Sevil Yasar, Marilyn Albert, Hanzhang Lu

Neurology Faculty Publications

INTRODUCTION: Vascular contributions to cognitive impairment and dementia (VCID) represent a major factor in cognitive decline in older adults. The present study examined the relationship between cerebrovascular reactivity (CVR) measured by magnetic resonance imaging (MRI) and cognitive function in a multi-site study, using a predefined hypothesis.

METHODS: We conducted the study in a total of three analysis sites and 263 subjects. Each site performed an identical CVR MRI procedure using 5% carbon dioxide inhalation. A global cognitive measure of Montreal Cognitive Assessment (MoCA) and an executive function measure of item response theory (IRT) score were used as outcomes.

RESULTS: CVR …