Digital Commons Network^™

Pfas Exposure And Human Health Risk Management - A Policy Review, Callie Sierra Totaro

Master's Projects and Capstones

For centuries, new chemicals and compounds have been invented to improve material longevity or make a product cheaper to produce. Throughout this time, emerging chemicals have often gone through inadequate testing that may not consider all long term environmental and human health effects before they have gone to market in the United States. As a result, thousands of harmful chemicals have ended up in the food supply, water sources, and everyday items of people in the United States with the negative health effects often not being discovered for decades after the start of circulation. By this point, removal and assessment …

Bioinformatic Analysis Of Hypothetical Genes In Lactococcus Lactis Ssp. Il1403:, Jennifer Tangires

Undergraduate Theses and Capstone Projects

The human gastrointestinal tract (GIT) contains various microbial organisms involved in many processes of physiological homeostasis. Among these resident microbes are lactic acid bacteria (LAB). These bacteria, almost all of which belong to the order Lactobacillales, are able to produce lactic acid and play an important role in food preservation because they produce bacteriocins. Bacteriocins are antimicrobial proteins that are used to fight off related bacteria in their environment that are competing for the same resources. This study focuses on exploring a specific LAB strain, Lactococcus lactis ssp. IL1403 where 21.9% of its predicted genes have not yet been assigned …

Impact Of Temperature On Children’S Nutrition: A Comparative Study Of Three Ecological Regions Of Nepal, Prakriti Shakya

Master's Theses

Nutrition obtained during the growth period of childhood significantly influences long-term well-being and overall productivity, ultimately contributing to the economy of a society. However, weather shocks can wreak havoc by damaging crops, changing yields of important crops and disrupting market access, which directly impacts the food intake of both adults and children. When these adverse events occur during childhood, short term and long term inadequacy in nutrition as well as disease incidence can cause malnutrition leading to stunted growth and cognitive impairment that may persist into adulthood, affecting the labor market and increasing health expenditure. To address this issue, we …

Downregulation Of Dax-1 Expression Via Mirna Overexpression As A Mechanism To Potentiate Breast Cancer, Nicholas C. Devito

Master's Theses

The orphan nuclear receptor DAX-1 (Dosage Sensitive Sex Reversal, Adrenal Hypoplasia Congenita, critical region on the X chromosome, gene 1) plays a key role in mammalian sex determination and steroidogenesis. In addition to these canonical examples, DAX-1 has been shown to play a contradictory role in cancer development. While DAX-1 is overexpressed in lung and prostate cancer, it is downregulated in breast cancer. One of the explanations for the paradoxical role of DAX-1 in cancer development could be microRNA (miRNA) dysregulation. After broadly surveying over 96 miRNAs historically upregulated in MCF7 breast cancer cells, we compared the expression of DAX-1 …

The Impact Of Index Based Livestock Insurance (Ibli) On Child Nutrition In Marsabit County, Kenya, Jackson Kadyampakeni

Master's Theses

The study uses six rounds of Index-Based Livestock Insurance (IBLI) panel surveys (2009 – 2015) for Northern Kenya’s Marsabit county to investigate the impact of IBLI on child nutrition and household food security. We employ Ordinary Least Squares (OLS) and Instrumental Variable (IV) regressions to account for potential endogeneity in IBLI uptake. The results indicate that while IBLI uptake significantly improves the intake of key nutrients such as Vitamin A, protein, iron, and fruits and vegetables, it does not translate into significant improvements in child nutrition status, as measured by Mid-Upper Arm Circumference (MUAC) z-scores. Significant negative effects of age …

Biodiversity Loss & Urban Heat: A Nature- Based Wildlife Policy For The Las Vegas Metro, Zachary Billot

Student Research

As the population of the Las Vegas Metro continues to grow, new developments expand on the periphery. As Las Vegas continues to increase in size and develop further into wildlife habitat, not only are native animals and plants endangered, but residents are at risk of increasingly dangerous urban heat given the increase in impervious cover that makes Las Vegas the 2nd fastest warming metro in the U.S. This policy brief examines current policy and practice in place to highlight the need for positive human-wildlife interaction that will address the growing threat of biodiversity loss and heat vulnerability. This policy brief …

Land Use Intensification And Bio-Resource Utilisation In The South Pacific Islands, David Lopez Cornelio

International Journal of Islands Research

The long and gradual colonisation of the Pacific islands created settlements of cohesive social networks that fused or were displaced by western ways of life, trade and governance through the centuries. In this paper, a historical review of the processes of island discovery, plants domestication, and of land use practices are discussed alongside the main socioeconomic drivers of land cover change. The native trees of the South Pacific constitute an invaluable resource for sustainable development; they were used and domesticated for thousands of years but logging, commercial agriculture, mining, the introduction of exotic species and urban expansion are threatening them …

Misstatements, Misperceptions, And Mistakes In Controlling For Covariates In Observational Research, Xiaoxin Yu, Roger S Zoh, David A Fluharty, Luis M Mestre, Danny Valdez, Carmen D Tekwe, Colby J Vorland, Yasaman Jamshidi-Naeini, Sy Han Chiou, Stella T Lartey, David B Allison

Children’s Nutrition Research Center Staff Publications

We discuss 12 misperceptions, misstatements, or mistakes concerning the use of covariates in observational or nonrandomized research. Additionally, we offer advice to help investigators, editors, reviewers, and readers make more informed decisions about conducting and interpreting research where the influence of covariates may be at issue. We primarily address misperceptions in the context of statistical management of the covariates through various forms of modeling, although we also emphasize design and model or variable selection. Other approaches to addressing the effects of covariates, including matching, have logical extensions from what we discuss here but are not dwelled upon heavily. The misperceptions, …

The Long-Term Effects Of Blood Urea Nitrogen Levels On Cardiovascular Disease And All-Cause Mortality In Diabetes: A Prospective Cohort Study, Hongfang Liu, Xiaoqin Xin, Jinghui Gan, Jungao Huang

Faculty, Staff and Student Publications

BACKGROUND: The long-term effects of blood urea nitrogen(BUN) in patients with diabetes remain unknown. Current studies reporting the target BUN level in patients with diabetes are also limited. Hence, this prospective study aimed to explore the relationship of BUN with all-cause and cardiovascular mortalities in patients with diabetes.

METHODS: In total, 10,507 participants with diabetes from the National Health and Nutrition Examination Survey (1999-2018) were enrolled. The causes and numbers of deaths were determined based on the National Death Index mortality data from the date of NHANES interview until follow-up (December 31, 2019). Multivariate Cox proportional hazard regression models were …

Draining Chicago’S Food Swamps: Legal Approaches, Sofia Fernandez

DePaul Journal of Health Care Law

Public health is a collective responsibility of society to improve the health and wellbeing of communities, focusing on preventing disease and promoting health as opposed to providing medical care for those already ill.1 The law consists of rules issued and enforced by government entities “through which populations organize their governments, regulate social and economic interactions, and guide behavior.”2 Public health law exists at the intersection of these two fields, comprising “the legal powers and duties of the state to identify, prevent, and ameliorate risks to the health of populations, as well as the study of legal structures that have a …

Temporal And Spatial Influences On Fawn Summer Survival In Pronghorn Populations: Management Implications From Noninvasive Monitoring, Cole A. Bleke, Eric M. Gese, Juan J. Villalba, Shane B. Roberts, Susannah S. French

Wildland Resources Student Research

Monitoring vital rates allows managers to estimate trends in growth rates of ungulate populations. However, connecting the influence of nutrition on ungulate demography is challenging. Noninvasive sampling offers a low-cost, low-effort alternative for measuring nutritional indices, allowing for an increased understanding of the mechanistic relationships between environmental factors, nutrition, and specific population vital rates. We examined the temporal influence of intrinsic and extrinsic factors on pronghorn (Antilocapra americana) fawn recruitment. We collected fresh fecal samples from adult female pronghorn in five subpopulations spanning three sampling periods associated with critical maternal life-history stages (late gestation, early lactation, breeding season) …

Design And Implementation Of A Machine Learning Predictive Model For Crop Yield In Indoor Vertical Hydroponics Farming, Emna Bouzid

Theses and Dissertations

To optimize agricultural practices and address water scarcity, this work introduces Vertical Hydroponics and Machine Learning (ML) to smart agriculture, using data from Internet of Things (IoT) sensors to enhance crop production in low and medium-income countries, particularly Tunisia's, hydroponic farms. This research is an innovative approach to enhancing crop production within indoor vertical hydroponic systems by utilizing different ML predictive models and assessing their performance. This part was done at UALR while the data collection was done at MedTech, with 21 basil plants. This study compares Linear Regression, Long Short-Term Memory (LSTM), and Deep Neural Networks (DNN) for precision …

Hay Inventory And Purchasing Calculator For Horse Owners, Robyn L. Stewart, Brooklyne M. Wassel

Journal of Extension

The Hay Inventory and Purchasing Calculator for Horse Owners is an Excel-based tool for estimating hay needs and expenses for horse owners. Challenges with hay quality and availability can result in higher than expected costs for horse owners as they attempt to purchase enough horse-quality hay to meet their needs. Estimating intake requirements and creating a budget for hay purchasing is key for the effective management and profitability of equine operations. This tool can be used regardless of geographic location and will benefit a diverse audience including Extension educators, equine business owners, and horse owners.

Expanded Food And Nutrition Education Program Generates Economic Value Through Body Mass Index Improvement: A Cost-Benefit Analysis, Andrea Leschewski, M. Catalina Aragon, Dave Weatherspoon, Karen Barale, Garry Auld, Richard Acquah-Sarpong, Susan S. Baker

Journal of Extension

Prior economic evaluations of the Expanded Food and Nutrition Education Program (EFNEP) perform cost-benefit analyses (CBA) reliant on self-reported behavioral data and unvalidated criteria for disease prevention. This study aims to conduct a CBA of Colorado and Washington EFNEP using an objective biomarker, Body Mass Index, to monetize program benefits. A longitudinal study of a convenience sample of EFNEP participants was conducted utilizing a single-group pretest-posttest design. Results indicate Colorado and Washington EFNEP generates $9.23 of benefits per $1.00 of costs and demonstrate the feasibility and value of using biomarkers in economic evaluations of nutrition education interventions delivered through Extension.

Designing Future Agriculture: Design For Complex Systems And Cross-Cultural Interactions, Karina Madzari

Dartmouth College Master’s Theses

Climate change is now recognized by businesses as a major challenge, prompting the agribusiness sector to transform to meet sustainability goals. However, there are many ways to achieve sustainability. Precision agriculture and agroecology are two concepts that evolved from conventional and regenerative approaches respectively, and offer distinct perspectives on sustainability attainment. Precision agriculture relies on technological solutions like artificial intelligence (AI), robotics, gene editing, and carbon dioxide removal technologies (CDR) and aims to revolutionize industry operations through automatization. Agroecology, on the other hand, creates a symbiotic relationship between farming practices and ecosystem services. It aims to replace non-renewable resources with …

College Students’ Domestic Kitchen Food Safety Perceptions And Knowledge, Kailing Chen, Zhihong Lin, Isabelle Do Prado, Zahra Mohammad, Karla M. Acosta, Sujata A. Sirsat

Journal of Extension

This study investigates college students’ current food safety knowledge and food-handling perceptions and utilized an online survey which designed based on previous studies as method. The questionnaire measured respondents’ food safety knowledge and perception, and were divided into knowledge, attitudes and perception categories. The results show that college students significantly lacked in basic food safety knowledge as well as food handling skills and implies a high need to develop enhanced food safety resources for college students, especially on topics related to cross-contamination prevention, correct food preparation procedures, time and temperature control, and awareness of pathogens that cause foodborne illness.

Teens Teach Nutrition Virtually To Youth During Covid-19: Improved Leadership Skills And Health Behaviors, Wendy S. Wolfe, Jacqueline Davis-Manigaulte, Dana M. Wheeler, Emma R. Dhimitri, Josie G. Ford, Kieu A. Phan, Dylan G. Ratnarajah

Journal of Extension

The Choose Health Action Teens (CHAT) program of Cornell Cooperative Extension engages teens to teach a nutrition curriculum to younger youth, with the goal of enhancing the leadership skills and health behaviors of the teen teachers. Due to COVID-19, an in-person CHAT program in New York City was converted to virtual and implemented online during Summer 2020. Twelve teens, mentored by eight college interns, taught youth virtually in their homes. Quantitative and qualitative assessments demonstrated improvement in teen leadership and facilitation skills and health behaviors, and suggest that converting this type of programming to a virtual environment can be successful.

An Observational, Retrospective, Study To Assess Sehetna Wellness Program Impact On Employees’ Well-Being And Health, Wafaa Saeed, Lina Shaker, Laila Ghanem, Mohamed El Aziz, Omer Mostafa, Rabab Youssef

BAU Journal - Health and Wellbeing

Wellness is an ongoing process that leads to realizing one's full potential, with studies showing reduced inpatient admissions, healthcare costs, and improved health-related quality of life through participation in large-scale wellness programs. SEHETNA program is a wellness initiative conducted with the Egyptian Group for Import and Export (EGMED) to enhance employees’ well-being. This study aimed to assess the SEHETNA wellness program impact on the general health of employees. This is a retrospective descriptive observational study including employees enrolled in wellness program for up to 12-months in 2021. Data were entered and analyzed using SPSS. Descriptive analysis was done, categorical variables …

Duck Gut Metagenome Reveals The Microbiome Signatures Linked To Intestinal Regional, Temporal Development, And Rearing Condition, Lingyan Ma, Wentao Liu, Tao Zeng, Wen Wang, Qu Chen, Jiangchao Zhao, Guolong Zhang, Lizhi Lu, Hua Yang, Yingping Xiao

Animal Science Faculty Publications and Presentations

The duck gastrointestinal tract (GIT) harbors an abundance of microorganisms that play an important role in duck health and production. Here, we constructed the first relatively comprehensive duck gut microbial gene catalog (24 million genes) and 4437 metagenome-assembled genomes using 375 GIT metagenomic samples from four different duck breeds across five intestinal segments under two distinct rearing conditions. We further characterized the intestinal region-specific microbial taxonomy and their assigned functions, as well as the temporal development and maturation of the duck gut microbiome. Our metagenomic analysis revealed the similarity within the microbiota of the foregut and hindgut compartments, but distinctive …

Third-Party Fecal Microbiota Transplantation For High-Risk Treatment-Naïve Acute Gvhd Of The Lower Gi Tract, Zachariah Defilipp, Ashish V Damania, Haesook T Kim, Chia-Chi Chang, Areej El-Jawahri, Steven L Mcafee, Aj S Bottoms, Vesselina Toncheva, Melissa M Smith, Maria Dolaher, Lindsey Perry, Meghan White, Brittany Diana, Sheila Connolly, Bimalangshu R Dey, Matthew J Frigault, Richard A Newcomb, Paul V O'Donnell, Thomas R Spitzer, Michael K Mansour, Daniela Weber, Nadim J Ajami, Elizabeth Hohmann, Robert R Jenq, Yi-Bin Chen

Faculty, Staff and Student Publications

Disruption of the intestinal microbiome is observed with acute graft-versus-host disease (GVHD) of the lower gastrointestinal (LGI) tract, and fecal microbiota transplantation (FMT) has successfully cured steroid-refractory cases. In this open-label, single-arm, pilot study, third-party, single-donor FMT was administered in combination with systemic corticosteroids to participants with high-risk acute LGI GVHD, with a focus on treatment-naïve cases. Participants were scheduled to receive 1 induction dose (15 capsules per day for 2 consecutive days), followed by 3 weekly maintenance doses, consisting of 15 capsules per dose. The primary end point of the study was feasibility, which would be achieved if ≥80% …

Evaluating The Yield Of Surviving Plants From Early-Season Hail Damage In Corn: A Field Survey, I. P. Lisboa, Christopher A. Proctor, R W. Elmore, A. J. Mcmechan, N. D. Mueller, J. Wilson, G. Zobeck, Aaron Nygren, A. Bastidas, Osler Ortez

Department of Agronomy and Horticulture: Faculty Publications

Economic losses due to hailstorms acrossUS corn fields occur every year.Hailstorms result in leaf defoliation, decreasing photosynthetic area and impairing carbon assimilation and crop yield for all corn (Zea mays L.) development stages. However, more attention is often given to stand reductions rather than damage to stems or leaf defoliation. During the 2014 growing season, a natural hail event affected many areas of eastern Nebraska. Twelve affected corn fields were surveyed and included in this study. An injury score scale (1–5) was developed based on various injury and severity levels before the V6 (6-leaf corn growth stage) (six-collared leaves). …

The De-Domestication Of Ornithopus Sativus Brot. To Develop Cultivars With Physical Dormancy (Hardseed), Robert J. Harrison, Bradley J. Nutt, Ronald J. Yates, Belinda F. Hackney, John G. Howieson

Grain and Other Field Crops Research Articles

Ornithopus sativus Brot. (French serradella) is a forage legume that is well adapted to acidic coarse textured soils (sands) which are characterized by poor nutrition and an inability to retain water. During the process of domestication of O. sativus, there was an unintentional loss of seed physical dormancy (PY) thus compromising its self-regeneration after a cropping interval. Through mass screening of seed, we identified for the first time that heritable sources of PY exist in three populations of O. sativus. This rare genetic material was then incorporated into suitable genetic backgrounds of differing maturity through targeted hybridization. We demonstrated …

Improving Nutritional Delivery To Pediatric Patients While Using Continuous Renal Replacement Therapy, Jennifer Ruiz-Boada, Sarah Brunner, Tara Benton, Vimal Chadha

Research Days

This quality improvement guide aims to enhance early nutritional delivery to pediatric patients with renal failure who require renal replacement therapy.ng renal replacement therapy.

Us Neonatal Intensive Care Unit Registered Dietitian Nutritionists Salary Description And Correlates: Results Of A Survey, Rosa K. Hand, Sharon Groh-Wargo

Faculty Scholarship

Background: This survey described the compensation of neonatal intensive care unit (NICU) registered dietitian nutritionists (RDNs) in the United States and examined correlates of higher salaries within this group. Methods: A cross-sectional online survey was completed in 2021 by 143 NICU RDNs from 127 US hospitals who reported hourly wage in US dollars (USD). We used initial bivariate analyses to assess the relationship of selected institution-level and individual-level variables to hourly wage; the rank-sum test for binary variables; bivariate regression and Pearson correlation coefficients for continuous variables; the Kruskal–Wallis test for categorical variables. Variables with a compelling relationship to the …

Multifaceted Roles Of Meg3 In Cellular Senescence And Atherosclerosis, Xiao Cheng, Mohamed Sham Shihabudeen Haider Ali, Vijaya Bhaskar Baki, Matthew Moran, Huabo Su, Xinghui Sun

Department of Biochemistry: Faculty Publications

Background and aims: Long noncoding RNAs are involved in the pathogenesis of atherosclerosis. As long non-coding RNAs maternally expressed gene 3 (Meg3) prevents cellular senescence of hepatic vascular endothelium and obesity-induced insulin resistance, we decided to examine its role in cellular senescence and atherosclerosis.

Methods and Results: By analyzing our data and human and mouse data from the Gene Expression Omnibus database, we found that Meg3 expression was reduced in humans and mice with cardiovascular disease, indicating its potential role in atherosclerosis. In Ldlr^−/− mice fed a Western diet for 12 weeks, Meg3 silencing by chemically modified …

Towards Dignity: Understanding The Relationship Between Food Banks & The Right To Food In The United States, Marguerite Leek

Theses - ALL

In the United States, there is no legal right to food. The right to food is more than food security, it encompasses dignity, access, choice, financial security, and more. Rather than addressing food insecurity through a human rights-based approach, the US relies on a complex system of emergency food providers, including food banks. Food banks most often take a charity approach to providing individuals with food, failing to meaningfully recognize or address the structural causes of hunger and poverty. In recent years there have been increased efforts made by civil society to move conversation and state level policy in the …

Does Increased Productivity Ensure Food Security And Food Sovereignty? Case Study: Productivity, Food Security, And Gender Participation Within The Framework Of The “Sustenta” Project In Nampula Province, Mozambique., Arcenia Notilija Vilanculo

Theses - ALL

When food security and sovereignty are viewed from a gendered lens, critical questions arise concerning inclusive participation in food systems. While policymaking is pivotal in ensuring gender parity in these systems, the lack of stakeholder engagement and buy-in during the policy design process hinders governmental efforts to create and implement policies that effectively ensure food and nutritional security for all. This research examines agricultural productivity, food security, land tenure, and stakeholder engagement in the context of SUSTENTA project in Nampula. The methodology adopts a qualitative approach, incorporating data from semi-structured interviews, featuring predefined questions and topics and a thorough literature …

Intraguild Competition Is More Severe In Obligate Mutualisms Than In Facultative Mutualisms, Thomas Johnson

Theses - ALL

Mutualism, or the beneficial interaction of species, is an important and widespread interaction type in nature. Mutualist species exchange goods or services that benefit the species involved. These benefits can include protection from predators, parasites, and disease, dispersal of individuals, offspring, or gametes, and provisioning of various nutrients. Well-known mutualisms include the pollination of flowering plants by insects, birds, and other animals and the interaction between clownfish and sea anemones. Many mutualistic associations are less visible than these examples, as organisms often form beneficial relationships with microorganisms, like the many beneficial bacteria that live in the human gut, or the …

Standard Rodent Diets Differentially Impact Alcohol Consumption, Preference, And Gut Microbiome Diversity, Aline Zaparte, Evan Dore, Selby White, Franciely Paliarin, Cameron Gabriel, Katherine Copenhaver, Samhita Basavanhalli, Emily Garcia, Rishith Vaddavalli, Meng Luo, Christopher M. Taylor, David Allen Welsh, Rajani Maiya

School of Graduate Studies Faculty Publications

Alcohol use disorder (AUD) is a complex and widespread disease with limited pharmacotherapies. Preclinical animal models of AUD use a variety of voluntary alcohol consumption procedures to recapitulate different phases of AUD, including binge alcohol consumption and dependence. However, voluntary alcohol consumption in mice is widely variable, making it difficult to reproduce results across labs. Accumulating evidence indicates that different brands of commercially available rodent chow can profoundly influence alcohol intake. In this study, we investigated the effects of three commercially available and widely used rodent diet formulations on alcohol consumption and preference in C57BL/6 J mice using the 24 …

The Impact Of School-Based Education Program On Body Image In Middle School Students, Elizabeth Hendon

Honors Theses

Body dissatisfaction is an emerging public health concern and carries significant health-related consequences. These implications encompass mental health challenges, eating disorders, unhealthy weight management practices, adverse effects on self-esteem, and potential physical health consequences. Because adolescence is a critical period for healthy body image development due to age-related transitions occurring at this time, it is essential to implement an education program to promote positive body image. Educational programs focused on protective factors designed to enhance self-compassion can potentially improve body image, eating attitudes, and body satisfaction. School-based body image education programs aim to provide adolescents with the knowledge, skills, and …