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B.R. Wells Arkansas Rice Research Studies 2023, J. Hardke, X. Sha, N. Bateman Aug 2024

B.R. Wells Arkansas Rice Research Studies 2023, J. Hardke, X. Sha, N. Bateman

Arkansas Agricultural Experiment Station Research Series

Arkansas is the leading rice producer in the United States. The state represents 49.0% of total U.S. rice production and 49.6% of the total acres planted to rice in 2023. Rice cultural practices vary across the state and across the U.S. However, these practices are also dynamic and continue to evolve in response to changing political, environmental, and economic times. This survey was initiated in 2002 to monitor and record changes in the way Arkansas rice producers approach their livelihood. The survey was conducted by polling county extension agents in each of the counties in Arkansas that produce rice. Questions …


Cystic Fibrosis Pathogens Persist In The Upper Respiratory Tract Following Initiation Of Elexacaftor/Tezacaftor/Ivacaftor Therapy, Yasmin K. Hilliam, Catherine R. Armbruster, Glenn J. Rapsinski, Christopher W. Marshall, John Moore, Junu Koirala, Leah Krainz, Jordan R. Gaston, Vaughn S. Cooper, Stella E. Lee, Jennifer M. Bomberger Aug 2024

Cystic Fibrosis Pathogens Persist In The Upper Respiratory Tract Following Initiation Of Elexacaftor/Tezacaftor/Ivacaftor Therapy, Yasmin K. Hilliam, Catherine R. Armbruster, Glenn J. Rapsinski, Christopher W. Marshall, John Moore, Junu Koirala, Leah Krainz, Jordan R. Gaston, Vaughn S. Cooper, Stella E. Lee, Jennifer M. Bomberger

Biological Sciences Faculty Research and Publications

Elexacaftor/tezacaftor/ivacaftor (ETI) therapy has revolutionized the treatment of cystic fibrosis (CF) for most affected individuals but the effects of treatment on sinus microbiota are still unknown. Changes to the airway microbiota in CF are associated with disease state and alterations to the bacterial community after ETI initiation may require changes to clinical management regimens. We collected sinus swab samples from the middle meatus in an observational study of 38 adults with CF and chronic rhinosinusitis (CRS) from 2017 to 2021 and captured the initiation of ETI therapy. We performed 16S and custom amplicon sequencing to characterize the sinus microbiota pre- …


An Examination Of The Impact Of College Health And Wellness Courses On Mental Health – Two Paper Format: A Literature Review And A Comparison Of The Impact Of Two College Health And Wellness Courses On Affect, Perceived Stress, And Cognitive Distortions, Robin Phipps Woodall Aug 2024

An Examination Of The Impact Of College Health And Wellness Courses On Mental Health – Two Paper Format: A Literature Review And A Comparison Of The Impact Of Two College Health And Wellness Courses On Affect, Perceived Stress, And Cognitive Distortions, Robin Phipps Woodall

Boise State University Theses and Dissertations

Objective: To compare the impact of two 15-week health and wellness courses on mental health measures in college students. Participants: College student volunteers were recruited after enrolling in one of two 15-week health and wellness courses. Methods: The control course (N=19) had an ethical emphasis, and the experimental course (N=21) had a cognitive behavioral emphasis. Participants completed a demographic questionnaire and pre- and post-tests of the Perceived Stress Scale, the Positive and Negative Affect Schedule-General Form, and the Cognitive Distortion Questionnaire. Pre- to Post-Changes were analyzed using a mixed model repeated measures ANOVA between the two courses. Results: Both courses …


Enriching The Pcos Lifestyle, Callie Coleman Aug 2024

Enriching The Pcos Lifestyle, Callie Coleman

Electronic Theses and Dissertations

Polycystic Ovary Syndrome (PCOS) is an endocrine disorder affecting approximately 4 – 20% of women worldwide. It is associated with insulin resistance, fertility problems, and an increased susceptibility to chronic conditions through multiple inflammatory pathways. Women with PCOS are also at increased risk for disordered eating. The Mediterranean diet is associated with decreased inflammation and risk of chronic conditions, and intuitive eating principles are associated with decreased disordered eating patterns. The purpose of this study was to determine if a six-week nutrition education workshop incorporating information and skills related to both the Mediterranean lifestyle and intuitive eating principles can improve …


Elucidating The Roles Of Septin Proteins In Thermotolerance And Cell Wall Integrity In Cryptococcus Neoformans, Stephani S. Martinez Barrera Aug 2024

Elucidating The Roles Of Septin Proteins In Thermotolerance And Cell Wall Integrity In Cryptococcus Neoformans, Stephani S. Martinez Barrera

All Dissertations

Cryptococcus neoformans is a globally distributed fungal pathogen responsible for causing cryptococcal meningitis in immunocompromised individuals. This pathogenic yeast must adapt to changes in temperature upon entering the human host. Septin proteins are conserved filament-forming GTPases that assemble as higher-order complexes at the cell cortex to support cytokinesis and morphogenesis in fungal and animal cells. In C. neoformans, four septin homologs (Cdc3, Cdc10, Cdc11, and Cdc12) assemble at the mother-bud neck, contributing to cytokinesis through poorly understood mechanisms. C. neoformans strains lacking the septins Cdc3 or Cdc12 are viable at 25°C, but fail to proliferate at 37°C, and are …


The Effects Of An Acute Dose Of Cannabidiol On Health And Two-Mile Time Trial Performance, Elyssa Bell Aug 2024

The Effects Of An Acute Dose Of Cannabidiol On Health And Two-Mile Time Trial Performance, Elyssa Bell

Master's Theses

As more studies exploring the therapeutic effects of cannabidiol (CBD) in both clinical and non-clinical populations continue to increase, there is a renewed interest in the ability of CBD to affect performance. In fact, many anecdotal reports in the media and online suggest that CBD may improve performance. Unfortunately, very few studies support these claims and research in the area is limited. Purpose: The purpose of this study is to explore the effects of an acute dose of CBD on anxiety symptoms, GI distress, heart rate variability (HRV), heart rate (HR), blood pressure (BP), blood lactate (BL) rate of perceived …


Effects Of Increasing Cycling Cadence On Post-Cycling Gait Velocity: An Experimental Study, Nitu Lama Aug 2024

Effects Of Increasing Cycling Cadence On Post-Cycling Gait Velocity: An Experimental Study, Nitu Lama

Master's Theses

Previous research has shown that increasing cycling cadence, rather than the workrate, can result in improved post-cycling gait velocity. However, the specific threshold of cycling cadence required to bring about clinically meaningful changes in gait velocity remains unknown. To address this knowledge gap, our study aimed to determine the minimum incremental increase in cycling cadence that would lead to a significant improvement in post-cycling gait velocity. A total of 42 young adults participated in our study and were randomly assigned to one of three groups: TEN, TWENTY, and THIRTY. Each group was assigned to cycle at a cadence at the …


Linking Risk Preference, Women’S Empowerment, Farm Investment And Household Well-Being, Samuel Olusesi Olumide Aug 2024

Linking Risk Preference, Women’S Empowerment, Farm Investment And Household Well-Being, Samuel Olusesi Olumide

Department of Agricultural Economics: Dissertations, Theses, and Student Research

A nuanced understanding of intra-household dynamics can inform the design of more effective empowerment and agricultural investment policies. By integrating household risk preferences and empowerment dynamics, this work offers valuable insights into the complex mechanisms driving household welfare and provides a framework for future interventions to promote gender equality and economic development in rural settings. This thesis addresses three core hypotheses: first, that the spouses of risk-seeking male heads are more likely to be disempowered compared to those of risk-averse male heads; second, that households with risk-seeking male heads and disempowered spouses are likely to invest more in farming activities; …


Investigating Associations Between Activity And Performance Traits Across Three Breeds Of Swine Using NuTrack, Dalton R. Obermier Aug 2024

Investigating Associations Between Activity And Performance Traits Across Three Breeds Of Swine Using NuTrack, Dalton R. Obermier

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

Feed costs are the largest contributor towards the variable costs of pork production. To decrease feed cost while not sacrificing output requires an improvement in feed efficiency (FE). A potential approach to expand available phenotypes associated with FE is with activity tracking, yet the relationship between activity and performance is not well defined in swine. Therefore, the objective of this study was to quantify associations between activity and feed intake traits. Average daily feed intake (ADFI) was collected on 1,766 purebred boars of three genetic lines (Duroc, Landrace, and Yorkshire) using FIRE (Osborne Industries, Inc., Osborne, Kansas) at a testing …


Agronomic Practices To Enhance Weed Management, Department Of Primary Industries And Regional Development, Western Australia Aug 2024

Agronomic Practices To Enhance Weed Management, Department Of Primary Industries And Regional Development, Western Australia

Grains and other field crops factsheets

Some agronomic practices, such as crop choice and sequence and improving crop competition and pasture competition, can improve crop environment and growth, and the crop's ability to compete with weeds.


Food Waste Study At A School District In California, Monica Ibarra Aug 2024

Food Waste Study At A School District In California, Monica Ibarra

Electronic Theses, Projects, and Dissertations

This study is aimed at evaluating food leftovers and wastes among elementary school students by comparing their food preferences for different ethnic cuisines, developing strategies to reduce food waste, and an assessment of quality assurance of food served. Data were collected from a cafeteria at an elementary school located in California. The total number of students served each day at this elementary school was 475. Data were provided by the cafeteria staff after the lunch was served. It was observed that students preferred Chinese food (specifically, Orange Chicken) over Mexican (Beef Chalupas) and American (Turkey with Gravy) where100% of the …


Individually Randomized Trial Mislabeled As A Cluster-Randomized Trial Comment On: “Effectiveness Of Wearable Technology To Optimize Youth Soccer Players’ Off-Training Behaviour And Training Responses: A Cluster-Randomized Trial”, Jean Michel R S Leite, Jasmine Jamshidi-Naeini, Colby J Vorland, Lilian Golzarri-Arroyo, David B Allison Aug 2024

Individually Randomized Trial Mislabeled As A Cluster-Randomized Trial Comment On: “Effectiveness Of Wearable Technology To Optimize Youth Soccer Players’ Off-Training Behaviour And Training Responses: A Cluster-Randomized Trial”, Jean Michel R S Leite, Jasmine Jamshidi-Naeini, Colby J Vorland, Lilian Golzarri-Arroyo, David B Allison

Children’s Nutrition Research Center Staff Publications

No abstract provided.


Consumer Perceptions Of Hemp-Fed Aquaculture, Jillian Hyink Aug 2024

Consumer Perceptions Of Hemp-Fed Aquaculture, Jillian Hyink

Graduate Theses and Dissertations

Global demand for seafood has increased significantly over the past several decades and is projected to continue rising in the future. The volume of aquaculture production has also particularly increased to meet this demand in the United States and globally, offering a relatively sustainable supplement to wild fish supplies. However, conventional fish farming uses unsustainable quantities of fishmeal and fish oil as feed inputs, which raises the cost of production and introduces safety concerns associated with fish consumption. One currently underexplored potential alternative to fishmeal is hemp grain, which can provide an affordable and nutritious feed for carnivorous fish and …


The Impact Of Reactive Oxygen Species On Bactericidal Activity And Drug Resistance In Salmonella Typhimurium Upon Chlorine And Eugenol Exposure, Mohammed Aljuwayd Aug 2024

The Impact Of Reactive Oxygen Species On Bactericidal Activity And Drug Resistance In Salmonella Typhimurium Upon Chlorine And Eugenol Exposure, Mohammed Aljuwayd

Graduate Theses and Dissertations

Salmonella Typhimurium (S.T) is a foodborne pathogenic bacterium which causes salmonellosis in human beings. Chicken is the most common source of S.T contamination. In chapter I, I discuss the growth of the poultry industry, the role chickens play as Salmonella reservoirs, the spread of drug-resistant strains caused by chicken husbandry and antibiotic use, and how eugenol can be used in poultry feed to decrease Salmonella infections and improve intestinal health. In chapter Ⅱ, I summarize the role of reactive oxygen species (ROS) in bactericidal activity. In chapter Ⅲ, I describe the killing mechanism of sodium hypochlorite (NaOCl) and identify the …


Nutrient Intake And Nutritional Status Of Blood Cancer Patients At A Tertiary Hospital In India: A Cross-Sectional Descriptive Analysis Of Leukemia, Lymphoma And Multiple Myeloma, Enock Topisia, Loise Wamahiga Wang’Ondu Aug 2024

Nutrient Intake And Nutritional Status Of Blood Cancer Patients At A Tertiary Hospital In India: A Cross-Sectional Descriptive Analysis Of Leukemia, Lymphoma And Multiple Myeloma, Enock Topisia, Loise Wamahiga Wang’Ondu

Haematology and Oncology, East Africa

In 2018, there were an estimated 18 million cancer cases worldwide, with lymphoma, multiple myeloma, and leukemia contributing to a significant portion of these cases. Lymphoma accounted for 79,990 cases, multiple myeloma for 159,985 cases, and leukemia for 437,033 cases globally (AICR, 2018). In the United States alone, approximately 30,770 people are diagnosed with multiple myeloma each year. Multiple myeloma comprises about 1.8% of all cancers and around 10% of all “blood cancers,” which includes leukemia (Penn Medicine, 2020). India ranks third in the highest reported cases of blood cancer, following the United States and China, affecting more than 70,000 …


Alternative Methods For Finishing Beef Cattle: Effects On Performance, Carcass Quality, And Meat Characteristics, Michelle Johnson Aug 2024

Alternative Methods For Finishing Beef Cattle: Effects On Performance, Carcass Quality, And Meat Characteristics, Michelle Johnson

Graduate Theses and Dissertations

The objective of these studies was to evaluate the effects of alternative finishing methods on the live performance, carcass quality, and meat characteristics of beef steers. In study 1, treatments consisted of a conventional feedlot finishing diet with roughage included in the ration (FDLT); a high starch diet fed at 2-2.25% of BW with ad libitum access to bermudagrass pastures (STCH); or a high by-product diet fed at 2-2.25% of BW with ad libitum access to bermudagrass pastures (BYPD). Steers were fed their respective diets once daily and weighed every 28 days until deemed finished. Cattle were then transported and …


Understanding The Role Of The Microbiome In Infectious Disease, Developing Surveillance Tools, And Engineering Direct Fed Microbials To Improve Animal Health, Alison Clare (Bartenslager) Neujahr Aug 2024

Understanding The Role Of The Microbiome In Infectious Disease, Developing Surveillance Tools, And Engineering Direct Fed Microbials To Improve Animal Health, Alison Clare (Bartenslager) Neujahr

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

With the ever-increasing demand for animal protein and the continual need for the assurance of proper animal welfare, investigations of preventative strategies for diseases is greatly needed. Specifically in the cattle industry, infectious bovine keratoconjunctivitis (IBK), commonly known as pinkeye, causes a large economic loss to the producer. However, effective mitigation strategies are lacking. Partly, this is due to the lack of studies investigating the ocular microbiome. Therefore, studies investigating the bovine ocular microbiome are greatly needed to better understand IBK disease etiology. To this end, we investigated the changes in the ocular microbiome in animals before, during and after …


Exploring Equity In Introductory Biology Genetics Education, Sandy G. Phillips-Long Aug 2024

Exploring Equity In Introductory Biology Genetics Education, Sandy G. Phillips-Long

All Dissertations

The dissertation “Exploring Equity in Introductory Biology Genetics Education” delved into the critical examination of equity within undergraduate genetics education. Chapter One outlined the background, significance, research framework, and manuscripts included in this study. Chapter Two was a scoping review that provided an overview of the current pedagogical approaches in undergraduate genetics education. It identified six active learning pedagogies: Course-based Undergraduate Research Experience (CURE); group work; case-based learning; inquiry-based learning; Virtual Reality (VR); and Consider, Read, Elucidate the hypothesis, Analyze and interpret the data, and Think of the next Experiment (CREATE). Chapter Three was a systematic literature review investigating pedagogical …


Industrial Applications Of Molecular Techniques., Jesse Lee Rozsa Aug 2024

Industrial Applications Of Molecular Techniques., Jesse Lee Rozsa

Electronic Theses and Dissertations

Multidisciplinary research is vital in modern science. Combining molecular genetics with engineering disciplines such as material science, robotics, or 3D printing is not a new concept but one that can continue to lead to breakthroughs that will benefit society. Science does not and should not occur in a vacuum, and, in early 2020, the world saw the emergence of a pandemic that shifted the focus of scientific research for a time. This manuscript describes aspects of this journey and the fruit that was born from this historic event. In this dissertation, we used plants and bacteria to produce compounds that …


Use Of Herbicides Coated Onto Fertilizer And Applied Over-The-Top Of Cotton, Summer Linn Aug 2024

Use Of Herbicides Coated Onto Fertilizer And Applied Over-The-Top Of Cotton, Summer Linn

Graduate Theses and Dissertations

Cotton (Gossypium hirsutum L.) production faces numerous challenges, many related to weed management. A herbicide application method that focuses on combing resources that producers already have access to, such as herbicide-coated fertilizers, could be a practical approach for addressing late-season control of Palmer amaranth (Amaranthus palmeri S. Wats) and other problematic weed species. Two main factors would potentially impact the efficiency of utilizing this method: cotton tolerance to the application and weed control provided by the herbicide-coated fertilizers. Some considerations could affect the efficacy of these applications, such as when the treatments are applied and when they are activated by …


The Effects Of Cover Crop Adoption On Yield Distributions Under Extreme Drought, Emory Johnson Aug 2024

The Effects Of Cover Crop Adoption On Yield Distributions Under Extreme Drought, Emory Johnson

Graduate Theses and Dissertations

Increased frequency and severity of extreme weather events due to climate change negatively impact agriculture output. Of particular concern is the adverse impact of droughts on corn and soybean yields, as these crops represent a significant portion of cash crop receipts in the United States. Cover crops are one practice that has gained attention due to their agronomic benefits and their potential to reduce downside production risk for producers. This study focuses on the impact of cover crop adoption on corn and soybean yields during drought conditions. We use cover crop adoption data from the Operational Tillage Information System, RMA …


Cobblestone Farms, Fayetteville: A Study Of A Non-Profit Teaching Farm’S Volunteer Management Programs, Ariel Scholten Aug 2024

Cobblestone Farms, Fayetteville: A Study Of A Non-Profit Teaching Farm’S Volunteer Management Programs, Ariel Scholten

Graduate Theses and Dissertations

Non-profit teaching farms (NPTFs) represent a unique intersection of mission-driven non-profits, agricultural education, and sustainable food production. Despite their growing presence, research on NPTFs, particularly regarding volunteer management, remains limited. This thesis examines volunteer management practices at Cobblestone Farms (CF), a prominent NPTF in Northwest Arkansas, focusing on its strategies to engage and retain volunteers. Through qualitative methods including semi-structured interviews with staff and volunteers, the study identifies, describes, and evaluates key components of CF's volunteer management program. Major findings reveal that CF leverages digital media, online platforms like Give Pulse, and strategic partnerships to recruit and maintain volunteers. The …


L-Arabinose Induced Overexpression For Crystallographic Analysis Of The Spoiie Protein From Clostridioides Difficile, Danielle M. Maynard Aug 2024

L-Arabinose Induced Overexpression For Crystallographic Analysis Of The Spoiie Protein From Clostridioides Difficile, Danielle M. Maynard

Graduate Theses and Dissertations

The SpoIIE protein plays a crucial role in the sporulation process of Clostridioides difficile, a pathogen responsible for severe gastrointestinal diseases. Understanding the structural and functional aspects of SpoIIE is pivotal for deciphering its role in sporulation and exploring its potential as a therapeutic target. This study investigates the impact of varying concentrations of L-arabinose on the overexpression of SpoIIE in C. difficile, aiming to optimize protein yield and purity for subsequent crystallization and structural determination via X-ray crystallography. Using a recombinant expression system in Escherichia coli, different concentrations of L-arabinose were employed to induce SpoIIE overexpression. Protein purification was …


Diet Modification Reduces Pain And Improves Function In Adults With Osteoarthritis: A Systematic Review, Karen Stanfar, Corey Hawes, Mina Ghajar, Laura Byham-Gray, Diane R. Radler Aug 2024

Diet Modification Reduces Pain And Improves Function In Adults With Osteoarthritis: A Systematic Review, Karen Stanfar, Corey Hawes, Mina Ghajar, Laura Byham-Gray, Diane R. Radler

Health & Biomedical Sciences Faculty Publications

Background

The effect of dietary modifications on pain and joint function in adults with osteoarthritis (OA) is an emerging area of study. This systematic review aimed to evaluate if adults with OA who consume diets with a higher proportion of plant phenols and omega-3 fatty acids would have less pain and improved joint function than those with a higher proportion of saturated fatty acids, omega-6 fatty acids and refined carbohydrates.

Methods

Database searches of CINAHL (EBSCO), Clinical Trials (NIH-NLM), Cochrane Library (Wiley), Dissertation & Thesis Global (ProQuest), Embase (Elsevier), Medline (OVID), PubMed (NLM), Scopus (Elsevier), Web of Sciences (Clarivate) for …


Effect Of Chemical Enhancers On Transdermal Delivery Of Amiloride For Management Of Resistant Hypertension, Oluwatosin Tabitha Leshaodo Aug 2024

Effect Of Chemical Enhancers On Transdermal Delivery Of Amiloride For Management Of Resistant Hypertension, Oluwatosin Tabitha Leshaodo

Electronic Theses and Dissertations

Amiloride, a diuretic used for managing resistant hypertension, is hindered by low oral bioavailability and Gastrointestinal side effects, impacting patient compliance. This study investigates transdermal delivery as an alternative to reduce pill burden and improve adherence. Using dermatomed porcine ear skin, the research examined the passive transdermal delivery of amiloride and the effect of various chemical enhancers, including oleic acid, oleyl alcohol, tocopheryl polyethylene glycol succinate, and N-methyl-2-pyrrolidone, individually or in combination. A validated High-Performance Liquid Chromatography method, adhering to Internal Council for Harmonized guidelines (ICH), was employed for quantitative analysis. In vitro permeation studies, conducted using porcine skin and …


Abstracts Of The 12th Annual Mississippi Association Of Entomologists, Nematologists, And Plant Pathologists Meeting, October 30 And 31, 2023, Mississippi Association Of Entomologists, Nematologists, And Plant Pathologists Aug 2024

Abstracts Of The 12th Annual Mississippi Association Of Entomologists, Nematologists, And Plant Pathologists Meeting, October 30 And 31, 2023, Mississippi Association Of Entomologists, Nematologists, And Plant Pathologists

Midsouth Entomologist

No abstract provided.


Why Do Patients With Cancer Die?, Adrienne Boire, Katy Burke, Thomas R Cox, Theresa Guise, Mariam Jamal-Hanjani, Tobias Janowitz, Rosandra Kaplan, Rebecca Lee, Charles Swanton, Matthew G Vander Heiden, Erik Sahai Aug 2024

Why Do Patients With Cancer Die?, Adrienne Boire, Katy Burke, Thomas R Cox, Theresa Guise, Mariam Jamal-Hanjani, Tobias Janowitz, Rosandra Kaplan, Rebecca Lee, Charles Swanton, Matthew G Vander Heiden, Erik Sahai

Faculty, Staff and Student Publications

Cancer is a major cause of global mortality, both in affluent countries and increasingly in developing nations. Many patients with cancer experience reduced life expectancy and have metastatic disease at the time of death. However, the more precise causes of mortality and patient deterioration before death remain poorly understood. This scarcity of information, particularly the lack of mechanistic insights, presents a challenge for the development of novel treatment strategies to improve the quality of, and potentially extend, life for patients with late-stage cancer. In addition, earlier deployment of existing strategies to prolong quality of life is highly desirable. In this …


Markov Models For Clinical Decision-Making In Radiation Oncology: A Systematic Review, Lucas B Mccullum, Aysenur Karagoz, Cem Dede, Raul Garcia, Fatemeh Nosrat, Mehdi Hemmati, Seyedmohammadhossein Hosseinian, Andrew J Schaefer, Clifton D Fuller Aug 2024

Markov Models For Clinical Decision-Making In Radiation Oncology: A Systematic Review, Lucas B Mccullum, Aysenur Karagoz, Cem Dede, Raul Garcia, Fatemeh Nosrat, Mehdi Hemmati, Seyedmohammadhossein Hosseinian, Andrew J Schaefer, Clifton D Fuller

Faculty, Staff and Student Publications

The intrinsic stochasticity of patients' response to treatment is a major consideration for clinical decision-making in radiation therapy. Markov models are powerful tools to capture this stochasticity and render effective treatment decisions. This paper provides an overview of the Markov models for clinical decision analysis in radiation oncology. A comprehensive literature search was conducted within MEDLINE using PubMed, following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Only studies published from 2000 to 2023 were considered. Selected publications were summarized in two categories: (i) studies that compare two (or more) fixed treatment policies using Monte Carlo simulation …


Why Do Patients With Cancer Die?, Adrienne Boire, Katy Burke, Thomas R Cox, Theresa Guise, Mariam Jamal-Hanjani, Tobias Janowitz, Rosandra Kaplan, Rebecca Lee, Charles Swanton, Matthew G Vander Heiden, Erik Sahai Aug 2024

Why Do Patients With Cancer Die?, Adrienne Boire, Katy Burke, Thomas R Cox, Theresa Guise, Mariam Jamal-Hanjani, Tobias Janowitz, Rosandra Kaplan, Rebecca Lee, Charles Swanton, Matthew G Vander Heiden, Erik Sahai

Faculty, Staff and Student Publications

Cancer is a major cause of global mortality, both in affluent countries and increasingly in developing nations. Many patients with cancer experience reduced life expectancy and have metastatic disease at the time of death. However, the more precise causes of mortality and patient deterioration before death remain poorly understood. This scarcity of information, particularly the lack of mechanistic insights, presents a challenge for the development of novel treatment strategies to improve the quality of, and potentially extend, life for patients with late-stage cancer. In addition, earlier deployment of existing strategies to prolong quality of life is highly desirable. In this …


Canine Parasites In Southern Nevada Urban Dog Parks: Paravec Study, Miklo Azrael A. Alcala Aug 2024

Canine Parasites In Southern Nevada Urban Dog Parks: Paravec Study, Miklo Azrael A. Alcala

UNLV Theses, Dissertations, Professional Papers, and Capstones

While dogs are one of humans’ greatest companions, they also serve as hosts for a multitude of parasites. Urban dog parks serve as environments where the transmission of diseases is likely to occur. Exposure to infective agents, contained within the soil, intermediate hosts (e.g., rodents, rabbits), and feces, can directly affect the health of dogs and their owners. Other factors that can further influence canine health include age, previous diagnoses of parasites/diseases, and migration. Many dog owners visit dog parks to encourage socialization and exercise. Such activities are meant to improve health, but unawareness of microbiological organisms can lead to …