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Full-Text Articles in Entire DC Network
Whole Body Vibration As An Innovative Intervention To Improve Physical Function And Vascular Health Within A Lifespan, Stephen Leroy Newhart Jr.
Whole Body Vibration As An Innovative Intervention To Improve Physical Function And Vascular Health Within A Lifespan, Stephen Leroy Newhart Jr.
Kinesiology Dissertations - Archive
Over the past several decades, technological advances in computers, transportation devices, and other automated devices have decreased the need for human locomotion and physical activity in the workplace and at home. The need to be physically active in order to sustain and prosper in life has been almost fully eliminated by these technological advances. As a result, sedentary patterns of living have become more prevalent throughout all socioeconomic levels. Age related injuries and conditions including falls and osteoporosis can be debilitating or life ending and have been associated with sedentary behaviors as these can lead to decreased range of motion, …
Differences In Falls And Recovery From A Slip Based On An Individual's Lower Extremity Corrective Response, Samuel J. Wilson, Paul T. Donahue, Charles C. Williams, Christopher M. Hill, Jeffrey D. Simpson, Dwight E. Waddell, Jeremy P. Loenneke, Harish Chander, Chip Wade, John C. Garner
Differences In Falls And Recovery From A Slip Based On An Individual's Lower Extremity Corrective Response, Samuel J. Wilson, Paul T. Donahue, Charles C. Williams, Christopher M. Hill, Jeffrey D. Simpson, Dwight E. Waddell, Jeremy P. Loenneke, Harish Chander, Chip Wade, John C. Garner
Faculty Publications
Background: Slips and falls account for high rates of injury and mortality in multiple populations. The corrective responses during the slip perturbation have been well documented. However, when a fall results from a slip, it is unclear which of these responses were inadequate.
Objective: The purpose of this study was to examine differences in lower extremity corrective responses of the slip recovery response between individuals who fall and those who recover.
Methodology: Sixty-four participants completed this study (32 males & 32 females). Participant’s gait kinematics and kinetics were collected during normal gait (NG) and an unexpected slip …
Let It Rest: Sleep And Health As Positive Correlates Of Forgiveness Of Others And Self-Forgiveness, Loren Toussaint, Andrew J. Gall, Alyssa Cheadle, David R. Williams
Let It Rest: Sleep And Health As Positive Correlates Of Forgiveness Of Others And Self-Forgiveness, Loren Toussaint, Andrew J. Gall, Alyssa Cheadle, David R. Williams
Faculty Publications
Objective: The present study examined forgiveness of others, self-forgiveness, sleep, and health in a nationally representative sample of United States adults. It was hypothesised that sleep would mediate the associations of forgiveness of others and self-forgiveness with health.
Design: A nationally representative survey of 1,423 United States adults.
Main Outcome Measures: Measures included forgiveness of others, self-forgiveness, sleep quantity, sleep quality, psychological distress, life satisfaction, and self-rated physical health.
Results: Forgiveness of others (β = .20, p < .001) and self-forgiveness (β = .11, p < .01) were associated with sleep and forgiveness of others (β = .24, p < .001) and self-forgiveness (β = .27, p < .001) were associated with health. Sleep was associated with health (β = .45, p < .001) and also acted as a mediator of the associations of forgiveness of others (β = .09, p < .01) and self-forgiveness (β = .05, p < .01) with health.
Conclusions: Forgiveness of others and self-forgiveness may attenuate emotions such as anger, regret, and rumination and provide …
Comparative Study On The Catechin Content And Antioxidant Capacity Of Different Types Of Tea In Jiangxi, Wang Xueyuan, Liu Jingyi, Hong Yanping, Li Yuwei, Ke Fajun, Chen Xinzhu, Yang Wuying
Comparative Study On The Catechin Content And Antioxidant Capacity Of Different Types Of Tea In Jiangxi, Wang Xueyuan, Liu Jingyi, Hong Yanping, Li Yuwei, Ke Fajun, Chen Xinzhu, Yang Wuying
Food and Machinery
The content of five kinds of catechins in eleven types of famous teas in Jiangxi, including Catechin, L-Epicatechin, (-)-epigallocatechin, Epigallocatechin gallate and (-)-Epicatechin gallate, was determined by high performance liquid chromatogra-phy. Moreover, the antioxidant capacities among the eleven types of tea were compared by measuring vitro antioxidant indexes, i.e. the free radical scavenging ability of DPPH, ABTS+, ferric reducing antioxidant power, and the total reduction ability. The results showed that the content of the five kinds of catechin in the tea was different, the content of total catechin did not differ significantly, and the contents of the total …
Effects Of Igf-1 Isoforms On Muscle Growth And Sarcopenia., Francesca Ascenzi, Laura Barberi, Gabriella Dobrowolny, Aline Villa Nova Bacurau, Carmine Nicoletti, Emanuele Rizzuto, Nadia Rosenthal, Bianca Maria Scicchitano, Antonio Musarò
Effects Of Igf-1 Isoforms On Muscle Growth And Sarcopenia., Francesca Ascenzi, Laura Barberi, Gabriella Dobrowolny, Aline Villa Nova Bacurau, Carmine Nicoletti, Emanuele Rizzuto, Nadia Rosenthal, Bianca Maria Scicchitano, Antonio Musarò
Faculty Research 2019
The decline in skeletal muscle mass and strength occurring in aging, referred as sarcopenia, is the result of many factors including an imbalance between protein synthesis and degradation, changes in metabolic/hormonal status, and in circulating levels of inflammatory mediators. Thus, factors that increase muscle mass and promote anabolic pathways might be of therapeutic benefit to counteract sarcopenia. Among these, the insulin-like growth factor-1 (IGF-1) has been implicated in many anabolic pathways in skeletal muscle. IGF-1 exists in different isoforms that might exert different role in skeletal muscle. Here we study the effects of two full propeptides IGF-1Ea and IGF-1Eb in …
Glycine Supplementation Extends Lifespan Of Male And Female Mice., Richard A Miller, David E Harrison, Clinton Michael Astle, Molly A. Bogue, Joel Brind, Elizabeth Fernandez, Kevin Flurkey, Martin Javors, Warren Ladiges, Christiaan Leeuwenburgh, Francesca Macchiarini, James Nelson, Alexey G Ryazanov, Jessica Snyder, Timothy M Stearns, Douglas E Vaughan, Randy Strong
Glycine Supplementation Extends Lifespan Of Male And Female Mice., Richard A Miller, David E Harrison, Clinton Michael Astle, Molly A. Bogue, Joel Brind, Elizabeth Fernandez, Kevin Flurkey, Martin Javors, Warren Ladiges, Christiaan Leeuwenburgh, Francesca Macchiarini, James Nelson, Alexey G Ryazanov, Jessica Snyder, Timothy M Stearns, Douglas E Vaughan, Randy Strong
Faculty Research 2019
Diets low in methionine extend lifespan of rodents, though through unknown mechanisms. Glycine can mitigate methionine toxicity, and a small prior study has suggested that supplemental glycine could extend lifespan of Fischer 344 rats. We therefore evaluated the effects of an 8% glycine diet on lifespan and pathology of genetically heterogeneous mice in the context of the Interventions Testing Program. Elevated glycine led to a small (4%-6%) but statistically significant lifespan increase, as well as an increase in maximum lifespan, in both males (p = 0.002) and females (p < 0.001). Pooling across sex, glycine increased lifespan at each of the three independent sites, with significance at p = 0.01, 0.053, and 0.03, respectively. Glycine-supplemented females were lighter than controls, but there was no effect on weight in males. End-of-life necropsies suggested that glycine-treated mice were less likely than controls to die of pulmonary adenocarcinoma (p = 0.03). Of the 40 varieties of incidental pathology evaluated in these mice, none were increased to a significant degree by the glycine-supplemented diet. In parallel analyses of the same cohort, we found no benefits from TM5441 (an inhibitor of PAI-1, the primary inhibitor of tissue and urokinase plasminogen activators), inulin (a source of soluble fiber), or aspirin at either of two doses. Our glycine results strengthen the idea that modulation of dietary amino acid levels can increase healthy lifespan in mice, and provide a foundation for further investigation of dietary effects on aging and late-life diseases.
Auditory Radiation And Cognitive Decline: Probabilistic Tractography Study, Adryanna Tucker
Auditory Radiation And Cognitive Decline: Probabilistic Tractography Study, Adryanna Tucker
Honors Theses
The relationship between hearing loss and Alzheimer’s disease has been studied for many years. Previous studies have shown a negative correlation between the two. In our study, we investigated the relationship between the strength of the auditory radiation connections and the severity of cognitive decline. To do so, we assessed probabilistic tractography using DTI data of the primary auditory pathway. Further, we assessed the level of cognition using the Alzheimer's Disease Assessment Scale-Cog to determine the relationship between the auditory connections assessed in each patient and that patient’s level of cognitive decline. We found that FA and AD were positively …
Visual And Verbal Serial List Learning In Patients With Statistically-Determined Mild Cognitive Impairment., Victor Wasserman, Sheina Emrani, Emily F Matusz, David Miller, Kelly Davis Garrett, Katherine A Gifford, Timothy J Hohman, Angela L Jefferson, Rhoda Au, Rod Swenson, David J Libon, Consortium For Clinical And Epidemiological Neuropsychological Data Analysis (Cenda).
Visual And Verbal Serial List Learning In Patients With Statistically-Determined Mild Cognitive Impairment., Victor Wasserman, Sheina Emrani, Emily F Matusz, David Miller, Kelly Davis Garrett, Katherine A Gifford, Timothy J Hohman, Angela L Jefferson, Rhoda Au, Rod Swenson, David J Libon, Consortium For Clinical And Epidemiological Neuropsychological Data Analysis (Cenda).
Rowan-Virtua School of Osteopathic Medicine Departmental Research
Background and Objective: Prior research with patients with mild cognitive impairment (MCI) suggests that visual versus verbal episodic memory test performance may be more sensitive to emergent illness. However, little research has examined visual versus verbal episodic memory performance as related to MCI subtypes.
Research Design and Methods: Patients were diagnosed with non-MCI, amnestic MCI (aMCI), and combined mixed/dysexecutive MCI (mixed/dys MCI). Visual and verbal episodic memory were assessed with the Brief Visuospatial Memory Test-Revised (BVMT-R) and the 12-word Philadelphia (repeatable) Verbal Learning Test (P[r]VLT), respectively.
Results: BVMT-R and P(r)VLT scores yielded similar between-group patterns of performance. Non-MCI patients scored …
Pilot Study Of Empathy In Bilingual Adults, Libby Moberg
Pilot Study Of Empathy In Bilingual Adults, Libby Moberg
Theses/Capstones/Creative Projects
Empathy is of critical public health importance due to its association with relationship satisfaction and well-being (Davis & Oathout, 1987; Davis, 1983). There is growing evidence that bilingual individuals may have higher levels of empathy (Javor, 2016). One potential mechanism for this relationship is that bilingual individuals tend to have higher levels of executive functioning (Costa et al, 2008), which is linked to higher empathy because individuals are able to more easily adopt others’ perspectives. Previous studies examining this question have largely relied on self-report questionnaires assessing empathy as a general tendency (i.e., trait). No studies have examined differences in …
Young Germ Cell Depleted Ovaries In Post-Reproductive Mice And Its Effects On Immune Function, Mckenna Walters
Young Germ Cell Depleted Ovaries In Post-Reproductive Mice And Its Effects On Immune Function, Mckenna Walters
Undergraduate Honors Capstone Projects
It has previously been shown that young, cycling ovarian transplantation in aged female mice increased the general health and life span in regard to their post-reproductive health. It has further been hypothesized that this enhancement of health is directly influenced by the ovarian somatic cells. To address this hypothesis, transplants of young germ cell depleted and germ cell containing ovaries were performed on female mice. The purpose of this study is to continue to discern the reproductive influence on aging health, specifically in the area of immunological well-being. Control group mice were separated by age and treatment mice were subsequently …
Manipulation Of Ovarian Function Significantly Influenced Glucose Metabolism In Cba/J Mice, Kyleigh Ann Tyler
Manipulation Of Ovarian Function Significantly Influenced Glucose Metabolism In Cba/J Mice, Kyleigh Ann Tyler
Undergraduate Honors Capstone Projects
Menopause is associated with a decline in overall health in women. One health aspect impacted is glucose metabolism. As women experience menopause, their metabolism declines dramatically. The current study addressed the influence of ovarian somatic cells on the improvement of metabolic health through transplantations of young, germ cell-depleted ovaries. The purpose of this study is to expand the understanding of female reproductive health on metabolism. Control mice were grouped by age and treatment mice were age-matched. Treatment mice were placed into one of three groups: 1) mice received germ cell-depleted ovaries, 2) mice received germ cell-containing ovaries, and 3) mice …
The Effects Of A Yoga Intervention On Cognitive Function In Older Adults, Elizabeth Edwards
The Effects Of A Yoga Intervention On Cognitive Function In Older Adults, Elizabeth Edwards
All Graduate Plan B and other Reports, Spring 1920 to Spring 2023
Cognitive decline and reduced cognitive function presents a serious risk to the older adult population. As the population of individuals over the age of 65 continues to increase, this presents a need for effective solutions to help people sustain healthy, independent lifestyles. Currently, physical activity is recommended for physical health in older adults and has shown evidence in maintaining cognitive function. In particular, the mind-body practice of yoga is a promising form of physical exercise that shows positive cognitive benefits. While the effects of yoga appear to be promising, the current literature is lacking scientific rigor. This study investigated the …
Latino Stepcouples’ Experiences Two Years After Stepfamily Education And A Narrative Study Regarding Changes In A Latino Stepfamily Two Years After Stepfamily Education, Sheryl Ann Goodey
Latino Stepcouples’ Experiences Two Years After Stepfamily Education And A Narrative Study Regarding Changes In A Latino Stepfamily Two Years After Stepfamily Education, Sheryl Ann Goodey
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
There are two studies in this dissertation. Both are about couples in a stepfamily who attended stepfamily education called, Smart Steps: Embrace the Journey. The first study explored how 13 Latino stepcouples felt the concepts they learned in stepfamily education influenced their couple relationship, parenting, and their family. Participants ranged in age from 25 to 43. They were interviewed two years after participating in the course. They talked about positive changes that happened in their couple relationship, parenting relationship, and their family as a result of participating in stepfamily education. It was also found that the course helped them …
A Comparison Of Multiple Wearable Technology Devices Heart Rate And Step Count Measurements During Free Motion And Treadmill Based Measurements, Szu-Ping Lee, Jeffrey Montes, Richard Tandy, John Young, James Navalta
A Comparison Of Multiple Wearable Technology Devices Heart Rate And Step Count Measurements During Free Motion And Treadmill Based Measurements, Szu-Ping Lee, Jeffrey Montes, Richard Tandy, John Young, James Navalta
Physical Therapy Faculty Research
Introduction: Wearable Technology Devices are used to promote physical activity. It is unknown whether different devices measure heart rate and step count consistently during walking or jogging in a free motion setting and on a treadmill. Purpose: To compare heart rate and step count values for the Samsung Gear 2, FitBit Surge, Polar A360, Garmin Vivosmart HR+, Scosche Rhythm+ and the Leaf Health Tracker in walking and jogging activities. Methods: Forty volunteers participated. Devices were worn simultaneously in randomized configurations. 5-minute intervals of walking and jogging were completed in free motion and treadmill settings with matching paces. Heart rates at …
The Impact Of Power Training On Balance And Visual Feedback Removal, Juliana Bouton
The Impact Of Power Training On Balance And Visual Feedback Removal, Juliana Bouton
Senior Honors Theses
Because power training has been known to augment stability, the purpose of this study was to assess whether the removal of visual input affects lower limb muscle power production in young women who are resistance trained to the same degree it affects the untrained. This provided insight as far as the need for resistance training protocols in a largely untrained visually impaired population. To study this, fourteen college-aged female participants (18-23 years) performed a seated double-leg press on a leg sled machine, isolating power production of the lower limbs. After establishing baselines, which involved finding an average of power produced …
Program And Proceedings: Nebraska Academy Of Sciences 1880–2019, 139th Anniversary Year, One Hundred-Twenty-Ninth Annual Meeting, April 12, 2019
Nebraska Academy of Sciences: Programs and Proceedings
Program
Aeronautics and Space Science
Collegiate Academy: Biology
Biological and Medical Sciences
Chemistry and Physics
Teaching and Learning the Dynamics of Cellular Respiration Using Interactive Computer Simulations Workshop
Life After College: Building Your Resume for the Future Workshop
Collegiate Academy: Chemistry and Physics
Aeronautics and Space Science, Poster Session
Maiben Memorial Lecture: David Swanson
Anthropology
Applied Science and Technology
Earth Science
Environmental Sciences
Teaching of Science and Math
Integration Of Heterogeneous Functional Genomics Data In Gerontology Research To Find Genes And Pathway Underlying Aging Across Species., Jason A. Bubier, George L Sutphin, Timothy J Reynolds, Ron Korstanje, Axis Fuksman-Kumpa, Erich J Baker, Michael A Langston, Elissa J Chesler
Integration Of Heterogeneous Functional Genomics Data In Gerontology Research To Find Genes And Pathway Underlying Aging Across Species., Jason A. Bubier, George L Sutphin, Timothy J Reynolds, Ron Korstanje, Axis Fuksman-Kumpa, Erich J Baker, Michael A Langston, Elissa J Chesler
Faculty Research 2019
Understanding the biological mechanisms behind aging, lifespan and healthspan is becoming increasingly important as the proportion of the world's population over the age of 65 grows, along with the cost and complexity of their care. BigData oriented approaches and analysis methods enable current and future bio-gerontologists to synthesize, distill and interpret vast, heterogeneous data from functional genomics studies of aging. GeneWeaver is an analysis system for integration of data that allows investigators to store, search, and analyze immense amounts of data including user-submitted experimental data, data from primary publications, and data in other databases. Aging related genome-wide gene sets from …
Trunk Muscle Activation During Dynamic Sling Training Exercises, Tobias Morat, Denis Holzer, Rieke Trumpf
Trunk Muscle Activation During Dynamic Sling Training Exercises, Tobias Morat, Denis Holzer, Rieke Trumpf
International Journal of Exercise Science
International Journal of Exercise Science 12(1): 590-601, 2019. The purpose of this study was to examine the level of trunk muscle activation to characterize different dynamic sling training exercises. Thirty-six young adults (25±3 years, 1.78±0.1 m, 71.5±10.4 kg) performed six different sling training exercises while muscle activation of eight different trunk muscles was measured unilaterally by surface electrodes. Four of the exercises were conducted at two different difficulty levels (an easy and a hard version) by changing the body angle. The six sling training exercises differed regarding muscle activation, with significant differences (p< 0.05) between the three body parts (front, side, back). High muscle activations (76-87%) of the (front) trunk flexor muscles were measured. The back muscles tested reached more than half of their peak reference trial values only during one exercise tested. Regarding the side muscles, three of the sling exercises achieved muscle activations of 60% and higher (66-92%). All eight trunk muscles tested demonstrated a significantly (p< 0.05) higher muscle activation in the harder version compared with the easy version. Based on the results, the sling training exercises tested in this study seem to be most effective for the abdominal muscles. As assumed based on the former literature, changing the body angle during sling training exercises is shown to be a feasible way of adjusting the intensity of sling training. This could potentially be used in longitudinal sling training studies to assure a controlled, progressively increasing training intervention.
Acarbose Improves Health And Lifespan In Aging Het3 Mice., David E Harrison, Randy Strong, Silvestre Alavez, Clinton M Astle, John Digiovanni, Elizabeth Fernandez, Kevin Flurkey, Michael Garratt, Jonathan A L Gelfond, Martin A Javors, Moshe Levi, Gordon J Lithgow, Francesca Macchiarini, James F Nelson, Stacey J Sukoff Rizzo, Thomas J Slaga, Timothy M Stearns, John Erby Wilkinson, Richard A Miller
Acarbose Improves Health And Lifespan In Aging Het3 Mice., David E Harrison, Randy Strong, Silvestre Alavez, Clinton M Astle, John Digiovanni, Elizabeth Fernandez, Kevin Flurkey, Michael Garratt, Jonathan A L Gelfond, Martin A Javors, Moshe Levi, Gordon J Lithgow, Francesca Macchiarini, James F Nelson, Stacey J Sukoff Rizzo, Thomas J Slaga, Timothy M Stearns, John Erby Wilkinson, Richard A Miller
Faculty Research 2019
To follow-up on our previous report that acarbose (ACA), a drug that blocks postprandial glucose spikes, increases mouse lifespan, we studied ACA at three doses: 400, 1,000 (the original dose), and 2,500 ppm, using genetically heterogeneous mice at three sites. Each dose led to a significant change (by log-rank test) in both sexes, with larger effects in males, consistent with the original report. There were no significant differences among the three doses. The two higher doses produced 16% or 17% increases in median longevity of males, but only 4% or 5% increases in females. Age at the 90th percentile was …
Effect Of Dual-Task Walking On Long-Range Correlations In People With Parkinson's Disease, Shane Meltz
Effect Of Dual-Task Walking On Long-Range Correlations In People With Parkinson's Disease, Shane Meltz
UNO Student Research and Creative Activity Fair
Parkinson’s Disease (PD) causes gait to be more variable and more random. Gait variability is related to disease severity, and may be a marker of fall risks. Gait in PD is attention-dependent, meaning a distraction while walking could be detrimental. The effects of dual-task walking on gait variability in PD are unclear (in particular fractal fluctuations). This study will determine if dual-task walking impacts stride-to-stride variability compared to normal walking in people with Parkinson’s Disease. We predict that dual-tasking will lead to more random stride-to-stride variability in people with PD, compared to controls. Also, within the PD group, we predict …
Pilot Study Of Empathy In Adults, Libby Moberg
Pilot Study Of Empathy In Adults, Libby Moberg
UNO Student Research and Creative Activity Fair
Empathy is of critical public health importance due to its association with relationship satisfaction and well-being (Davis & Oathout, 1987; Davis, 1983). There is growing evidence that bilingual individuals may have higher levels of empathy (Javor, 2016). One potential mechanism for this relationship is that bilingual individuals tend to have higher levels of executive functioning (Costa et al, 2008), which is linked to higher empathy because individuals are able to more easily adopt others’ perspectives. Previous studies examining this question have largely relied on self-report questionnaires assessing empathy as a general tendency (i.e., trait). No studies have examined differences in …
Escaping Death: Naloxone's Chemical Nature And Potential To Combat The Opioid Epidemic, Abigale Miller
Escaping Death: Naloxone's Chemical Nature And Potential To Combat The Opioid Epidemic, Abigale Miller
Honors Program: Senior Projects (Public)
Naloxone is a life-saving drug with the ability to reverse an opioid overdose. As the opioid epidemic’s death toll rises, we can turn to Naloxone as a tool to combat the crisis. The epidemic, born of corruption, has a wide reach among the people of the United States, with especially firm grasps on middle-aged people, sufferers of chronic pain, white Americans and those living in the eastern portion of the country. Naloxone’s elegant design saves lives by effectively competing for a position on an opioid biding receptor in the brain to almost instantly end an overdose and restore normal breathing. …
An Altered Spatiotemporal Gait Adjustment During A Virtual Obstacle Crossing Task In Patients With Diabetic Peripheral Neuropathy, Chun-Kai Huang, Vijay Shivaswamy, Pariwat Thaisetthawatkul, Lynn Mack, Nicholas Stergiou, Ka-Chun Siu
An Altered Spatiotemporal Gait Adjustment During A Virtual Obstacle Crossing Task In Patients With Diabetic Peripheral Neuropathy, Chun-Kai Huang, Vijay Shivaswamy, Pariwat Thaisetthawatkul, Lynn Mack, Nicholas Stergiou, Ka-Chun Siu
Journal Articles
This study investigates spatiotemporal gait adjustments that occur while stepping over virtual obstacles during treadmill walking in people with/without diabetic peripheral neuropathy (DPN). Eleven adults with Type 2 diabetes mellitus, ten DPN, and 11 age-matched healthy adults (HTY) participated in this study. They stepped over forthcoming virtual obstacles during treadmill walking. Outcomes such as success rate, spatiotemporal gait characteristics during obstacle crossing, and correlations between these variables were evaluated. The results partially supported our hypotheses that when comparing with HTY and DM, people with DPN adopted a crossing strategy which decreased obstacle crossing success rate and maximal toe elevation, …
Unintentional Bathtub Drowning Deaths Among Those Aged 65 Years And Older In Australia, Amy E. Peden, Richard C. Franklin, John H. Pearn M.D., Alison J. Mahony
Unintentional Bathtub Drowning Deaths Among Those Aged 65 Years And Older In Australia, Amy E. Peden, Richard C. Franklin, John H. Pearn M.D., Alison J. Mahony
International Journal of Aquatic Research and Education
When compared with other age groups, fatal drowning rates among seniors have stayed static. This study identifies causal factors in unintentional bathtub drowning deaths among people aged 65 years and over. This study is a 10-year (2003-2012) total population retrospective survey of all unintentional bathtub (baths, spa baths and showers) drowning deaths afflicting people aged 65 years and over. Data were sourced from the Australian National Coronial Information System. Risk factors and circumstantial variables were analysed including sex, age, activity prior to drowning, alcohol, drugs, pre-existing medical conditions, living circumstances, time until found, and performance of cardio-pulmonary resuscitation (CPR). There …
Triple Hop For Distance As A Predictor Of Lower Extremity Performance In Firefighter Equipment, Sean M. Rogers, Zachary K. Winkelmann, Lindsey E. Eberman, Kenneth E. Games
Triple Hop For Distance As A Predictor Of Lower Extremity Performance In Firefighter Equipment, Sean M. Rogers, Zachary K. Winkelmann, Lindsey E. Eberman, Kenneth E. Games
International Journal of Exercise Science
International Journal of Exercise Science 12(6): 515-525, 2019. The objective of this study was to examine the predictive value of the Triple Hop for Distance (THD) physical performance test to assess lower extremity (LE) strength and power in individuals donning firefighter personal protective equipment (PPE). Thirty-one healthy participants completed the THD in firefighter PPE on both the dominant and non-dominant limb. Dependent variables included LE power (vertical jump height [cm]) on a jump mat, and LE strength of the quadriceps and hamstrings (peak torque [Nm]) on an isokinetic dynamometer. THD was a strong predictor of LE power on the dominant …
Efficacy Of Taurine Against Aluminum Maltolate-Induced Apoptosis In Sh-Sy5y Cells Via Reduction Of Oxidative Stress, Endoplasmic Reticulum Stress, And Mitochondrial Dysfunction, Bi-Yu Liu, Yuh-Ju Lee, Hsian-Chin Jen, Deng-Fwu Hwang
Efficacy Of Taurine Against Aluminum Maltolate-Induced Apoptosis In Sh-Sy5y Cells Via Reduction Of Oxidative Stress, Endoplasmic Reticulum Stress, And Mitochondrial Dysfunction, Bi-Yu Liu, Yuh-Ju Lee, Hsian-Chin Jen, Deng-Fwu Hwang
Journal of Marine Science and Technology–Taiwan
Aluminum (Al) is one of the most abundant elements on the earth’s crust and is used in various industrial applications. However, Al is known to be associated with various neurodegenerative diseases. Taurine is a free amino acid presents at high concentrations in the brain and is crucial for neuron development. Here, the protective effects of taurine against Al-induced neurotoxicity were investigated. Al, at a concentration of 600 M, induced apoptosis of and cell cycle arrest in human neuroblastoma SH-SY5Y cells. Additionally, Al induced a 55% increase in the levels of reactive oxygen species and inhibited mitochondrial membrane potential up to …
Regulation Of Respiration And Apoptosis By Cytochrome C Threonine 58 Phosphorylation, Junmei Wan, Hasini A. Kalpage, Asmita Vaishnav, Jenney Liu, Icksoo Lee, Gargi Mahapatra, Alice A. Turner, Matthew P. Zurek, Qinqin Ji, Carlos T. Moraes, Maurice-Andre Recanati, Lawrence I. Grossman, Arthur R. Salomon, Brian Fp Edwards, Maik HüTtemann
Regulation Of Respiration And Apoptosis By Cytochrome C Threonine 58 Phosphorylation, Junmei Wan, Hasini A. Kalpage, Asmita Vaishnav, Jenney Liu, Icksoo Lee, Gargi Mahapatra, Alice A. Turner, Matthew P. Zurek, Qinqin Ji, Carlos T. Moraes, Maurice-Andre Recanati, Lawrence I. Grossman, Arthur R. Salomon, Brian Fp Edwards, Maik HüTtemann
Biochemistry and Molecular Biology Faculty Publications
Cytochrome c (cytc) is a multifunctional protein, acting as an electron carrier in the electron transport chain (ETC), where it shuttles electrons from bc1 complex to cytochrome c oxidase (COX), and as a trigger of type II apoptosis when released from the mitochondria. We previously showed that cytc is regulated in a highly tissue-specific manner: Cytc isolated from heart, liver, and kidney is phosphorylated on Y97, Y48, and T28, respectively. Here, we have analyzed the effect of a new Cytc phosphorylation site, threonine 58, which we mapped in rat kidney Cytc by mass spectrometry. We generated and overexpressed wild-type, phosphomimetic …
Zumba In The Postindustrial Midwest: Minority Women And Access To Physical Fitness, Selen Razon, Shannon Powers, Lindsay Pursglove, Dagny Zupin, Lawrence W. Judge
Zumba In The Postindustrial Midwest: Minority Women And Access To Physical Fitness, Selen Razon, Shannon Powers, Lindsay Pursglove, Dagny Zupin, Lawrence W. Judge
Kinesiology Faculty Publications
Historically, minority women have had limited access to health care resources. Healthy People 2020 identified the promotion of activity and wellness as a key for eliminating heath disparities in ethnic minorities, as minority women are not significant consumers of exercise programming. This study explored participation of a sample of underserved African American women in an individualized Zumba exercise program. The underserved sample was taken from a postindustrial Midwestern city. Participants (n = 35, Mage = 45.75) completed a 4-month aerobic intervention program offered through an accessible gym. At program completion, they responded to a semistructured survey that gauged reasons for …
Cognitive Processes That Indirectly Affect Olfactory Dysfunction In Parkinson's Disease, Attakias T. Mertens, Jonathan B. Santo, Katerina Markopoulou, Bruce A. Chase
Cognitive Processes That Indirectly Affect Olfactory Dysfunction In Parkinson's Disease, Attakias T. Mertens, Jonathan B. Santo, Katerina Markopoulou, Bruce A. Chase
Biology Faculty Publications
Introduction
Accurate early diagnosis of Parkinson's disease is hampered by its long prodromal period and the variable manifestations of its motor symptoms. While olfactory dysfunction can occur before motor-symptom onset and serve as a non-disease-specific diagnostic aid, its underlying causes are incompletely understood.
Methods
Correlation analyses, univariate density estimates, ANOVA and regression evaluated relationships between scores on the Montreal Cognitive Assessment and Hopkins Verbal Learning Test and those on the University of Pennsylvania Smell Identification Test in 1280 Parkinson's Progression Markers Initiative subjects placed into five diagnostic categories. Structural equation modeling identified cognitive measures having significant indirect effects on olfactory-function-test …
The Role Of Mtdna Mutation And Mitochondrial Dysfunction On The Aging Process, Starr Pericles
The Role Of Mtdna Mutation And Mitochondrial Dysfunction On The Aging Process, Starr Pericles
Honors College Theses
No abstract provided.