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Articles 1981 - 2010 of 50398
Full-Text Articles in Entire DC Network
Symbiotic Aspergillus Terreus Alleviates Drought And Waterlogged Stress In Zea Mays L., Hazrat Ali, Fayaz Asad, Naveen Dilawar, Vasila Sharipova, Imtiaz Ahmad, Abida Zeb
Symbiotic Aspergillus Terreus Alleviates Drought And Waterlogged Stress In Zea Mays L., Hazrat Ali, Fayaz Asad, Naveen Dilawar, Vasila Sharipova, Imtiaz Ahmad, Abida Zeb
Turkish Journal of Botany
The interaction concerning rhizospheric fungi and plants is essential for enhancing plant resilience in the face of abiotic stress conditions. This study investigated the effects of the rhizospheric fungus Aspergillus terreus on maize (Zea mays L.) growth under both drought and waterlogging conditions. Our findings confirmed that inoculation with A. terreus mitigated the adverse effects of drought and waterlogging conditions on maize growth. Plants treated with Aspergillus terreus (A. terreus) exhibited enhanced root and shoot length, fresh and dry weight as well as enhanced chlorophyll content in plants compared to control, under stress-related conditions. Compared to the control group, A. …
Comparative Analysis Of The Complete Chloroplast Genome Of The Rare Endemic Palm Pinanga Arinasae Witono From Bali, Indonesia, Ni Putu Sri Asih, Risha Amilia Pratiwi, Istiana Prihatini, Paramita Cahyaningrum Kuswandi, Evy Yulianti, Arief Priyadi
Comparative Analysis Of The Complete Chloroplast Genome Of The Rare Endemic Palm Pinanga Arinasae Witono From Bali, Indonesia, Ni Putu Sri Asih, Risha Amilia Pratiwi, Istiana Prihatini, Paramita Cahyaningrum Kuswandi, Evy Yulianti, Arief Priyadi
Turkish Journal of Botany
Pinanga arinasae is an endangered species endemic to Bali, Indonesia. Our study aims to characterize its chloroplast genome, compare it with other chloroplast genomes, including its phylogenetic position within the Arecoideae subfamily, and identify potential molecular markers. P. arinasae chloroplast genomes characterization involves Illumina-based sequencing, de novo genome assembly, gene annotation, amino acid frequency, codon usage pattern analysis, and Simple Sequence Marker (SSR) identification. Comparative analysis include phylogenetic tree reconstruction, comparison of amino acid frequency, codon usage pattern, SSR number, inverted repeat junction arrangement, genome length, GC content, and gene number. Nucleotide diversity is calculated to identify substitution markers. The …
Nest Pollen Provisions From An Urban Population Of Megachile Campanulae (Hymenoptera: Megachilidae) In Minnesota Are Consistent With Oligolectic Classification., Lam D. Le, Thea A. Evans, Colleen Satyshur
Nest Pollen Provisions From An Urban Population Of Megachile Campanulae (Hymenoptera: Megachilidae) In Minnesota Are Consistent With Oligolectic Classification., Lam D. Le, Thea A. Evans, Colleen Satyshur
The Great Lakes Entomologist
The conservation of bees is crucial for maintaining the essential ecological services they provide. Understanding bee species' risk of extinction is a key part of conservation efforts, and can include assessment of dietary specialization, which has been linked to higher extinction risk. Dietary specialization in bees, called oligolecty, occurs when females select pollen only from closely related plants to feed their larvae. While the solitary bee, Megachile (Chelostomoides) campanulae (Robertson 1903), has been associated with flowers in the genus Campanula L. (Campanulaceae: Asterales), evidence from pollen analysis is limited, and dietary classification is reported inconsistently. This study examined dietary specialization …
Nocturnal Flight Periodicity Of Caddisflies (Trichoptera) Along The Lake Huron Shoreline Of Drummond Island, Michigan (Usa), Robert A. Haack, David Houghton
Nocturnal Flight Periodicity Of Caddisflies (Trichoptera) Along The Lake Huron Shoreline Of Drummond Island, Michigan (Usa), Robert A. Haack, David Houghton
The Great Lakes Entomologist
Over 7000 caddisfly specimens, representing 33 species in 10 families, were collected between sunset and sunrise on 12 nights: three nights each during early July and early August in both 2023 and 2024. Collections were made on the southwestern side of Drummond Island along the shoreline of Lake Huron. Sampling occurred for five minutes at 15-minute intervals from near sunset (21:00) to 01:00 and then once again at 03:00 and 05:00. Nocturnal flight periodicity was broadly similar between years and months, with mean caddisfly abundance and species richness peaking at about one hour after sunset. Mean species accumulation varied between …
Initial Changes In Ground Beetle (Carabidae: Coleoptera) Assemblages After Creating Gaps Of Varying Sizes In Mature Northern Hardwoods Forests In Wisconsin, Robert A. Haack, Robert E. Acciavatti, Toby R. Petrice, Robert L. Davidson, Terry F. Strong
Initial Changes In Ground Beetle (Carabidae: Coleoptera) Assemblages After Creating Gaps Of Varying Sizes In Mature Northern Hardwoods Forests In Wisconsin, Robert A. Haack, Robert E. Acciavatti, Toby R. Petrice, Robert L. Davidson, Terry F. Strong
The Great Lakes Entomologist
Managers of northern hardwood forests in the Great Lakes region create gaps in the forest canopy of various sizes during harvesting to achieve different silvicultural objectives. Single-tree harvesting favors recruitment of shade-tolerant tree species by creating small gaps in the canopy, whereas group selection creates larger gaps that can favor shade-intolerant tree species. We evaluated changes in carabid beetle abundance and diversity in harvest-created gaps of five sizes (gap diameters of 6, 10, 20, 30, and 46 m) and uncut forests in northern Wisconsin where sugar maple (Acer saccharum) was the dominant tree species. Gaps were cut during …
Treatment Of Tics In Pediatric Patients With Neurodevelopmental Disorders, Faiza Ahmad
Treatment Of Tics In Pediatric Patients With Neurodevelopmental Disorders, Faiza Ahmad
Research Colloquium
Background: The prevalence of chronic and transient tic disorders in children with neurodevelopmental delays is substantially higher than in the general pediatric population. Disorders including Tourette’s Syndrome, Chronic Persistent Motor Tic Disorder or Provisional Tic Disorder, can present challenges in treatment when comorbid neurodevelopmental disorders. Children with Autism Spectrum Disorder (ASD), Down’s Syndrome or other developmental delays may not be able to participate in first-line behavioral interventions like CBIT (Comprehensive Behavioral Intervention for Tics) therapy. Therefore, optimization of pharmacologic treatment is often necessary in this population, especially in the case of severe, refractory tics. Additionally, pharmacologic treatment can be …
Arbuscular Mycorrhizal Fungi As Key Drivers Of Plant Resilience: Mechanisms Of Stress Adaptation In Saline Environments, Rayna Elizabeth Koberstein
Arbuscular Mycorrhizal Fungi As Key Drivers Of Plant Resilience: Mechanisms Of Stress Adaptation In Saline Environments, Rayna Elizabeth Koberstein
Dissertations and Theses
Arbuscular mycorrhizal fungi (AMF) play a critical role in mediating plant responses to environmental stress, yet their ecological significance in saline wetland restoration remains underexplored. This greenhouse experiment investigated the effects of salinity, root-zone barrier type (solid, mesh, none), and neighboring species identity on AMF colonization and physiological responses in three native estuarine plants: Carex densa, Juncus patens, and Scirpus microcarpus. Results demonstrated species-specific physiological responses to salinity, with Juncus patens showing greater resilience in maintaining photosynthetic efficiency (Fv/Fm) and percent cover at higher salinity levels, while Scirpus microcarpus exhibited a significant decline. Mesh barriers, which permitted …
Connecting Innovation And Trust Through Translational Sciences – A Need For A Community Focus And Effective Education Strategiess, Filipa Godoy-Vitorino, Michelle Borrero, Josué Pérez-Santiago, Rubén García-García, Candelaria Gomez-Manzano
Connecting Innovation And Trust Through Translational Sciences – A Need For A Community Focus And Effective Education Strategiess, Filipa Godoy-Vitorino, Michelle Borrero, Josué Pérez-Santiago, Rubén García-García, Candelaria Gomez-Manzano
Faculty, Staff and Student Publications
Report of a conference held in Puerto Rico, this article highlights how interdisciplinary translational science-anchored in education, public trust, and equity-can accelerate innovation in cancer therapy while empowering underserved communities through inclusive training, collaboration, and research participation.
The Economic Burden Of Covid-19 In A Region With Stringent Response Measures: A Case Study Of Taiwan, Elise Chia-Hui Tan, Fei-Yuan Hsiao, Ming-Chin Yang
The Economic Burden Of Covid-19 In A Region With Stringent Response Measures: A Case Study Of Taiwan, Elise Chia-Hui Tan, Fei-Yuan Hsiao, Ming-Chin Yang
Journal of Food and Drug Analysis
The COVID-19 pandemic has imposed a significant economic burden globally, particularly in regions with stringentresponse measures. This study aimed to assess the economic impact of COVID-19 in Taiwan, focusing on both directand indirect costs. A cost-of-illness analysis was conducted, utilizing data from the Taiwan Centers for Disease Control(CDC), national databases, epidemiological studies, and economic surveys. The analysis included both direct costs (e.g.,hospital admissions, outpatient care) and indirect costs (e.g., productivity losses due to long COVID, absenteeism, caregiving duties). The study encompassed Taiwan's population of 23.2 million, with particular attention to age-specific impacts on economic outcomes. The total economic burden of …
Nanovesicles Derived From Protocorm-Like Bodies Of Dendrobium Officinal Enhance Corneal Epithelial Repair And Reduce Inflammation In Dry Eye Disease Models, Bao Yuqing, Peng Chengyu, Zhang Fenglei, Zheng Yuqiang, Zhang Mingqi, He Wei
Nanovesicles Derived From Protocorm-Like Bodies Of Dendrobium Officinal Enhance Corneal Epithelial Repair And Reduce Inflammation In Dry Eye Disease Models, Bao Yuqing, Peng Chengyu, Zhang Fenglei, Zheng Yuqiang, Zhang Mingqi, He Wei
Journal of Food and Drug Analysis
Plant-derived nanovesicles (PDNVs) offer a promising, biocompatible therapeutic platform. In this study, we isolatednanovesicles from protocorm-like bodies of Dendrobium officinale (PLBs-NVs) and evaluated their efficacy in dry eyedisease (DED) models. PLBs-NVs protected human corneal epithelial cells against hyperosmotic stress, supportedwound repair, and inhibited inflammation in vitro. In a desiccating stress-induced DED mouse model, topical PLBs-NVstreatment significantly restored tear secretion, reduced corneal epithelial damage, and lowered levels of proinflammatorycytokines. These results suggest that PLBs-NVs are a safe, natural, and effective therapeutic strategy for DED, sup-porting their potential for future clinical translation in ocular surface disorders.
The Rhythm Of Decline: Circadian Disruption In Neurodegeneration, Jeewanjot Singh, Devinder Kumar, Jasleen Kaur, Amanpreet Singh
The Rhythm Of Decline: Circadian Disruption In Neurodegeneration, Jeewanjot Singh, Devinder Kumar, Jasleen Kaur, Amanpreet Singh
Journal of Food and Drug Analysis
Alzheimer's disease (AD) is a progressive neurodegenerative disorder with a multifactorial etiology involving genetic,environmental, and metabolic factors. Among these, circadian rhythm disruption has emerged as a crucial but under-explored contributor to disease progression. The circadian system, regulated by the suprachiasmatic nucleus (SCN),controls essential physiological functions such as the sleep-wake cycle, metabolism, and neuroendocrine signaling.Disruption of this system has been increasingly linked to key pathological features of AD, including amyloid-betaaccumulation, tau hyperphosphorylation, and neuroinflammation. This review critically examines the mechanistic roleof circadian misalignment in AD by analyzing studies on sleep disturbances, SCN degeneration, metabolic dysregu-lation, clock gene polymorphisms (BMAL1, CLOCK, PER, …
In Vivo And In Vitro Perspectives In Parkinson's Disease: Mechanisms And The Role Of Phytomedicine, Jeewanjot Singh, Devinder Kumar
In Vivo And In Vitro Perspectives In Parkinson's Disease: Mechanisms And The Role Of Phytomedicine, Jeewanjot Singh, Devinder Kumar
Journal of Food and Drug Analysis
Parkinson's disease (PD) is a progressive neurodegenerative disorder marked by dopaminergic neuronal loss,oxidative stress, neuroinflammation, and a-synuclein aggregation. Despite advances, current treatments only offersymptomatic relief without altering disease progression. This review aims to evaluate the therapeutic potential of plant-derived phytochemicals in PD through evidence from both in vivo and in vitro experimental models. Key findingsindicate that rodent models (e.g., MPTP, rotenone) and neuronal cell lines (e.g., SH-SY5Y) help replicate PD pathologyand mechanistic insights. Phytochemicals such as baicalein, morin, ferulic acid, and bacopa demonstrate neuroprotectiveeffects via antioxidant, anti-inflammatory, and mitochondrial-stabilizing pathways. Nanotechnology and brain orga-noids further improve translational relevance. In conclusion, …
Global Research Trends On Avocado Oil And Its Fatty Acid Composition: A Bibliometric Review, Ahmad Kamrullah Aras, Abdul Rohman
Global Research Trends On Avocado Oil And Its Fatty Acid Composition: A Bibliometric Review, Ahmad Kamrullah Aras, Abdul Rohman
Journal of Food and Drug Analysis
The high content of unsaturated fatty acids in avocado oil (Persea americana) has prompted in-depth exploration across research subjects. This study uses bibliometric analysis to assess global research trends on avocado oil and its fatty acid composition from 2004 to 2024. The search string retrieved 255 articles from the Scopus database and then analyzed using R BibliometriX and VOSviewer software. These tools analyze descriptive structures and collaborative patterns and create network data maps. For comparison, we separated the data into two research periods, namely 2004-2013 and 2014-2024. There was a significant increase in the number of publications, with …
The Chromosome Complement Of Male Chrysoperla Rufilabris (Burmeister, 1839), With Evidence Of Distance Segregation In Meiosis I, Valoria G. Maslin, Allison M. Eisenhauer, Leocadia V. Paliulis
The Chromosome Complement Of Male Chrysoperla Rufilabris (Burmeister, 1839), With Evidence Of Distance Segregation In Meiosis I, Valoria G. Maslin, Allison M. Eisenhauer, Leocadia V. Paliulis
Faculty Journal Articles
Neuropteran insects display a phenomenon called distance segregation during male meiosis I, where the X and Y chromosomes are unconnected from prometaphase I through anaphase I. Here we investigate chromosome number and patterns of chromosome segregation of a previously unstudied Neuropteran: the green lacewing, Chrysoperla rufilabris (Burmeister, 1839). Testes of male C. rufilabris were isolated and prepared following a chromosome squash method. Living meiosis I spermatocytes were also imaged. The data revealed a chromosome number of 2n=12 in males (2n=10+XY) and evidence of distance segregation of X and Y chromosomes in meiosis I spermatocytes.
Impression Motivations And Mental Health In Collegiate Athletes And Musicians: The Benefits Of Promoting Virtues, Mary L. Inman, Olufemi A. Oluyedun, Erin Moran, Brendyn Mroz, Madison Mccreery
Impression Motivations And Mental Health In Collegiate Athletes And Musicians: The Benefits Of Promoting Virtues, Mary L. Inman, Olufemi A. Oluyedun, Erin Moran, Brendyn Mroz, Madison Mccreery
Faculty Publications
This study identifies two key impression-management motivations that arise in public settings: promoting virtues and preventing harm to one’s image. We explored their impact on mental health—specifically, socially-based perfectionism and depressive symptoms. Drawing from regulatory-focus theory, we predicted promotion motivations would predict strong mental health, prevention motivations would predict poor mental health, and promotion motivations would buffer against the negative effects of prevention motivations. Collegiate athletes and musicians (N = 262) completed validated measures of impression motivation, perfectionism, and depressive symptoms. Results revealed that athletes reported lower levels of perfectionism and depressive symptoms than did musicians. Across both groups, …
Warming Induces Unexpectedly High Soil Respiration In A Wet Tropical Forest, Tana E. Wood, Colin Tucker, Aura M. Alonso-Rodríguez, M. Isabel Loza, Iana F. Grullón-Penkova, Molly A. Cavaleri, Christine S. O'Connell, Sasha C. Reed
Warming Induces Unexpectedly High Soil Respiration In A Wet Tropical Forest, Tana E. Wood, Colin Tucker, Aura M. Alonso-Rodríguez, M. Isabel Loza, Iana F. Grullón-Penkova, Molly A. Cavaleri, Christine S. O'Connell, Sasha C. Reed
Biology, Chemistry, and Environmental Sciences Faculty Articles and Research
Tropical forests are a dominant regulator of the global carbon cycle, exchanging more carbon dioxide with the atmosphere than any other terrestrial biome. Climate models predict unprecedented climatic warming in tropical regions in the coming decades; however, in situ field warming studies are severely lacking in tropical forests. Here we present results from an in situ warming experiment in Puerto Rico, where soil respiration responses to +4 oC warming were assessed half-hourly for a year. Soil respiration rates were 42-204% higher in warmed relative to ambient plots, representing some of the highest soil respiration rates reported for any …
33 Unresolved Questions In Nanoscience And Nanotechnology, Chad A Mirkin, Sarah Hurst Petrosko, Natalie Artzi, Koray Aydin, Austin Biaggne, C Jeffrey Brinker, Katherine E Bujold, Y Charles Cao, Rachel R Chan, Chaojian Chen, Peng-Cheng Chen, Xiaodong Chen, Olivier J G L Chevalier, Chung Hang Jonathan Choi, Richard M Crooks, Vinayak P Dravid, Jingshan S Du, Sasha B Ebrahimi, Hongyou Fan, Omar K Farha, C Adrian Figg, Tanner D Fink, Connor M Forsyth, Harald Fuchs, Franz M Geiger, Nathan C Gianneschi, Kyle J Gibson, David S Ginger, Sishi Guo, Justin S Hanes, Liangliang Hao, Jin Huang, Bryan M Hunter, Fengwei Huo, Jeongmin Hwang, Rongchao Jin, Shana O Kelley, Thomas J Kempa, Youngeun Kim, Sergej Kudruk, Sneha Kumari, Kaitlin M Landy, Ki-Bum Lee, Noel J Leon, Jun Li, Yuanwei Li, Zhiwei Li, Bin Liu, Guoliang Liu, Xiaogang Liu, Luis M Liz-Marzán, Jochen H Lorch, Taokun Luo, Robert J Macfarlane, Jill E Millstone, Milan Mrksich, Catherine J Murphy, Rajesh R Naik, Andre E Nel, Christopher Oetheimer, Jenny K Hedlund Orbeck, So-Jung Park, Benjamin E Partridge, Nicholas A Peppas, Michelle L Personick, Arindam Raj, Namrata Ramani, Michael B Ross, Stacey Barnaby Ross, Edward H Sargent, Tanushri Sengupta, George C Schatz, Dwight S Seferos, Tamar Seideman, Soyoung Eileen Seo, Bo Shen, Wooyoung Shim, Donghoon Shin, Ulrich Simon, Andrew J Sinegra, Peter T Smith, Alexander M Spokoyny, Peter J Stang, Alexander H Stegh, J Fraser Stoddart, Dayne F Swearer, Weihong Tan, Michelle H Teplensky, C Shad Thaxton, David R Walt, Mary X Wang, Zhe Wang, Wei David Wei, Paul S Weiss, Peter H Winegar, Younan Xia, Yi Xie, Xiaoyang Xu, Peidong Yang, Yiming Yang, Zihao Ye, Kuk Ro Yoon, Cuizheng Zhang, Hua Zhang, Ke Zhang, Liangfang Zhang, Xiaoyu Zhang, Ye Zhang, Zijian Zheng, Wenjie Zhou, Shengshuang Zhu, Wei Zhu
33 Unresolved Questions In Nanoscience And Nanotechnology, Chad A Mirkin, Sarah Hurst Petrosko, Natalie Artzi, Koray Aydin, Austin Biaggne, C Jeffrey Brinker, Katherine E Bujold, Y Charles Cao, Rachel R Chan, Chaojian Chen, Peng-Cheng Chen, Xiaodong Chen, Olivier J G L Chevalier, Chung Hang Jonathan Choi, Richard M Crooks, Vinayak P Dravid, Jingshan S Du, Sasha B Ebrahimi, Hongyou Fan, Omar K Farha, C Adrian Figg, Tanner D Fink, Connor M Forsyth, Harald Fuchs, Franz M Geiger, Nathan C Gianneschi, Kyle J Gibson, David S Ginger, Sishi Guo, Justin S Hanes, Liangliang Hao, Jin Huang, Bryan M Hunter, Fengwei Huo, Jeongmin Hwang, Rongchao Jin, Shana O Kelley, Thomas J Kempa, Youngeun Kim, Sergej Kudruk, Sneha Kumari, Kaitlin M Landy, Ki-Bum Lee, Noel J Leon, Jun Li, Yuanwei Li, Zhiwei Li, Bin Liu, Guoliang Liu, Xiaogang Liu, Luis M Liz-Marzán, Jochen H Lorch, Taokun Luo, Robert J Macfarlane, Jill E Millstone, Milan Mrksich, Catherine J Murphy, Rajesh R Naik, Andre E Nel, Christopher Oetheimer, Jenny K Hedlund Orbeck, So-Jung Park, Benjamin E Partridge, Nicholas A Peppas, Michelle L Personick, Arindam Raj, Namrata Ramani, Michael B Ross, Stacey Barnaby Ross, Edward H Sargent, Tanushri Sengupta, George C Schatz, Dwight S Seferos, Tamar Seideman, Soyoung Eileen Seo, Bo Shen, Wooyoung Shim, Donghoon Shin, Ulrich Simon, Andrew J Sinegra, Peter T Smith, Alexander M Spokoyny, Peter J Stang, Alexander H Stegh, J Fraser Stoddart, Dayne F Swearer, Weihong Tan, Michelle H Teplensky, C Shad Thaxton, David R Walt, Mary X Wang, Zhe Wang, Wei David Wei, Paul S Weiss, Peter H Winegar, Younan Xia, Yi Xie, Xiaoyang Xu, Peidong Yang, Yiming Yang, Zihao Ye, Kuk Ro Yoon, Cuizheng Zhang, Hua Zhang, Ke Zhang, Liangfang Zhang, Xiaoyu Zhang, Ye Zhang, Zijian Zheng, Wenjie Zhou, Shengshuang Zhu, Wei Zhu
Faculty, Staff and Student Publications
Significant advances in science and engineering often emerge at the intersections of disciplines. Nanoscience and nanotechnology are inherently interdisciplinary, uniting researchers from chemistry, physics, biology, medicine, materials science, and engineering. This convergence has fostered novel ways of thinking and enabled the development of materials, tools, and technologies that have transformed both basic and applied research, as well as how we address critical societal challenges. In this Nano Focus, we pose and explore 33 questions whose answers could profoundly impact fields such as energy, electronics, the environment, optics, and medicine. These questions highlight the need for deeper foundational understanding, improved tools …
Self-Transcendent Experiences As Promoters Of Ecological Wellbeing? Exploration Of The Evidence And Hypotheses To Be Tested, Amy Isham
The International Journal of Ecopsychology (IJE)
In recent years, much has been written on the role of different mental states and their potential to influence our way of thinking and, perhaps more importantly, the way we act. With the recent acceleration of environmental and mental health issues, alongside the limited effectiveness of existing interventions, an exploration of new approaches to deliver transformative change is required. We therefore explore the emerging potential of a type of mental state known as self-transcendent experiences (STEs) as a driver of ecological wellbeing. We focus on four types of STEs: those facilitated by experiences of flow, awe, and mindfulness, as well …
Quick Detection Of Citronellol And Geraniol In Yunnan Black Tea By Quechers-Gc-Ms, Yuhua Diao, Jing Wan, Yanhong Ma, Xian Chen, Yunlong Zhao
Quick Detection Of Citronellol And Geraniol In Yunnan Black Tea By Quechers-Gc-Ms, Yuhua Diao, Jing Wan, Yanhong Ma, Xian Chen, Yunlong Zhao
Journal of Food Science and Biotechnology
[Objective ] In view of the possible illegal addition of rose flavors (citronellol and geraniol ) to Yunnan black tea,a method was established for rapid detection of citronellol and geraniol based on QuEChERS-gas chromatography-mass spectrometry (QuEChERS-GC-MS ).[Method ] The procedure involved extracting Yunnan black tea samples with acetonitrile following water wetting.The extract was purified by QuEChERS dispersed solid phase extraction.It was detected under the selected ion monitoring (SIM ) mode and quantified by the external standard method.[Result ] Good linear relationships were observed for citronellol and geraniol within the mass concentration range from 0.05 to 5.00 μg/mL,with correlation coefficients (R2) …
Enhanced Expression Of Pepc Promotes The Synthesis Of 4-Hydroxyisoleucine By Corynebacterium Glutamicum, Chuhan Hu, Feng Shi
Enhanced Expression Of Pepc Promotes The Synthesis Of 4-Hydroxyisoleucine By Corynebacterium Glutamicum, Chuhan Hu, Feng Shi
Journal of Food Science and Biotechnology
[Objective ] This study aims to achieve the efficient biosynthesis of 4-hydroxyisoleucine (4-HIL ) in Corynebacterium glutamicum (C.glutamicum ).[Method ] The isoleucine (Ile) inducible promoters (PbrnFEN) of varying strengths were used to dynamically upregulate the expression of the isoleucine dioxygenase (IDO ) gene ido and the Vitreoscilla hemoglobin (VHb ) gene vgb.On this basis,constitutive promoters of different strengths were employed to enhance the expression of the phosphoenolpyruvate carboxylase (PEPC ) gene ppc and the pyruvate carboxylase gene pyc.[Result ] Among the recombinant strains harboring different P brnFEN promoters,strain C.glutamicum SN-I 7V7 (SN-I 7V7) was selected.After 144 h of fermentation with …
Metagenomic Characterization Of Gut Microbiota In Children With Autism Spectrum Disorder: Microbial Signatures And Modulation By Anti-Inflammatory Diet And Probiotics, Marysol Valencia-Buitrago, Rodrigo Dias Oliveira-Carvalho, Valbert Cardoso, Jessica Triviño-Valencia, Luisa Matilde Salamanca-Duque, Vanessa Martínez-Díaz, Jovanny Zabaleta, Narmer Fernando Galeano-Vanegas, Carlos Andrés Naranjo-Galvis
Metagenomic Characterization Of Gut Microbiota In Children With Autism Spectrum Disorder: Microbial Signatures And Modulation By Anti-Inflammatory Diet And Probiotics, Marysol Valencia-Buitrago, Rodrigo Dias Oliveira-Carvalho, Valbert Cardoso, Jessica Triviño-Valencia, Luisa Matilde Salamanca-Duque, Vanessa Martínez-Díaz, Jovanny Zabaleta, Narmer Fernando Galeano-Vanegas, Carlos Andrés Naranjo-Galvis
School of Medicine Faculty Publications
Background: Autism Spectrum Disorder (ASD) is increasingly associated with alterations in gut microbiota, intestinal permeability, and immune dysregulation. However, integrative studies exploring these mechanisms in Latin American populations are lacking. Objective: To characterize gut microbiota profiles in Colombian children with ASD and evaluate the effects of two microbiota-targeted interventions, an anti-inflammatory diet and a probiotic formulation, on microbial diversity and taxonomic composition. Methods: In a two-phase study, shotgun metagenomic sequencing was performed on fecal samples from 23 children with ASD and 7 typically developing (TD) controls. In the second phase, 17 children with ASD were randomized to receive a 12-week …
Biophobia And Pet Ownership: Can Having A Pet Mitigate Our Fear And Aversion Towards Nature?, Alexia Barrable
Biophobia And Pet Ownership: Can Having A Pet Mitigate Our Fear And Aversion Towards Nature?, Alexia Barrable
The International Journal of Ecopsychology (IJE)
Biophobia, which we defined as fear, disgust, or aversion toward natural environments or organisms, has received little empirical attention when compared to biophilia, despite its implications for human and planetary wellbeing. This mixed-methods study explores the relationship between pet ownership, biophobia, and nature connectedness among 373 English- speaking adults. Quantitative findings reveal that (M = 26.4) exhibit significantly lower levels of biophobia than non-pet owners (M = 30.1; U = 5179, Z = -2.95, p = .002, R = 0.27), although no significant differences in nature connectedness were found across pet ownership (U = 7033, Z = 0.31, p = …
Postscript: A Historical Interlude, George Conesa
Postscript: A Historical Interlude, George Conesa
The International Journal of Ecopsychology (IJE)
Ravens fly in circles above our heads. Coyote peers from the hedge but dares not. Kachinas have not danced. The awelos tried but youth went their own way.
Setd2 Suppresses Tumorigenesis In A Krasg12c-Driven Lung Cancer Model, And Its Catalytic Activity Is Regulated By Histone Acetylation, Ricardo J Mack, Natasha M Flores, Geoffrey C Fox, Hanyang Dong, Metehan Cebeci, Simone Hausmann, Tourkian Chasan, Jill M Dowen, Brian D Strahl, Pawel K Mazur, Or Gozani
Setd2 Suppresses Tumorigenesis In A Krasg12c-Driven Lung Cancer Model, And Its Catalytic Activity Is Regulated By Histone Acetylation, Ricardo J Mack, Natasha M Flores, Geoffrey C Fox, Hanyang Dong, Metehan Cebeci, Simone Hausmann, Tourkian Chasan, Jill M Dowen, Brian D Strahl, Pawel K Mazur, Or Gozani
Faculty, Staff and Student Publications
Histone H3 trimethylation at lysine 36 (H3K36me3) is a key chromatin modification that regulates fundamental physiological and pathological processes. In humans, SETD2 is the only known enzyme that catalyzes H3K36me3 in somatic cells and is implicated in tumor suppression across multiple cancer types. While there is considerable crosstalk between the SETD2-H3K36me3 axis and other epigenetic modifications, much remains to be understood. Here, we show that Setd2 functions as a potent tumor suppressor in a KRASG12C-driven lung adenocarcinoma (LUAD) mouse model, and that acetylation enhances SETD2 in vitro methylation of H3K36 on nucleosome substrates. In vivo, Setd2 ablation accelerates lethality in …
Age-Dependent Changes In Reproductive Behaviour And Success In A Long-Lived Beetle (Bolitotherus Cornutus), C. A. Greene, L. D. Mitchem, Vitor Dos Anjos , '21, E. D. Brodie Iii, Vincent A. Formica
Age-Dependent Changes In Reproductive Behaviour And Success In A Long-Lived Beetle (Bolitotherus Cornutus), C. A. Greene, L. D. Mitchem, Vitor Dos Anjos , '21, E. D. Brodie Iii, Vincent A. Formica
Biology Faculty Works
Age-related changes in behaviors often result in shifts in an individual’s competitive ability, reproductive success, and fitness. However, how mating behaviors, aggression, and mating success simultaneously change as individuals age in natural populations remains understudied. Investigating these age-dependent effects in wild populations could reveal how age-specific patterns shape social dynamics and influence natural selection. In this study, we ask how behaviors associated with mating and reproductive success vary across age in a wild metapopulation of a long-lived beetle, Bolitotherus cornutus. We used both cross-sectional and longitudinal data from a multi-year field study of individually marked beetles to investigate how …
Infusion Of Blood From Young And Old Mice Modulates Amyloid Pathology, Matias Pizarro, Ruben Gomez-Gutierrez, Ariel Caviedes, Catalina Valdes, Ute Woehlbier, Cristian Vargas, Mauricio Hernandez, Claudia Duran-Aniotz, Rodrigo Morales
Infusion Of Blood From Young And Old Mice Modulates Amyloid Pathology, Matias Pizarro, Ruben Gomez-Gutierrez, Ariel Caviedes, Catalina Valdes, Ute Woehlbier, Cristian Vargas, Mauricio Hernandez, Claudia Duran-Aniotz, Rodrigo Morales
Faculty, Staff and Student Publications
Alzheimer's disease (AD) is a neurodegenerative disease characterized by the accumulation of misfolded proteins in the brain. Recently, the impact of blood components in the progression of this disease has come to attention. This study investigates the effects of infusing blood from young and old wild-type mice into transgenic mice that model AD brain amyloidosis. Impaired memory and Aβ accumulation were observed in mice infused with blood from old donors. A proteomic analysis in the brain of these mice identified alterations in components related to synaptogenesis and the endocannabinoid system. The α2δ2 protein, associated with neuronal calcium regulation, was validated …
The Value Of Play In Improving Children’S Experiences With Healthcare, Kylie Howes
The Value Of Play In Improving Children’S Experiences With Healthcare, Kylie Howes
Family Perspectives
Hospitalization can be a distressing experience for children, often resulting in heightened anxiety and pain due to unfamiliar environments, procedures, and personnel. This literature review examines the effectiveness of Child Life Play Interventions—specifically Developmentally Supportive Play, Psychological Preparation Play, and Distraction Play—in reducing pediatric patients’ healthcare- related anxiety and pain. Developmentally supportive play provides children with familiar, age-appropriate activities that help maintain normalcy and routine, thereby reducing stress during extended hospital stays. Psychological preparation play uses role-playing and hands-on demonstrations to enhance children’s understanding of medical procedures, alleviating anxiety and decreasing perceived pain. Distraction play shifts children’s attention away from …
When Evidence Is Shocking: The Value Of Struggling With Uncomfortable Ideas, Cortney Evans-Stout, Christin L. Porter
When Evidence Is Shocking: The Value Of Struggling With Uncomfortable Ideas, Cortney Evans-Stout, Christin L. Porter
Family Perspectives
No abstract provided.
Marital Conflict And Male Depression: The Role Of Emotional Withdrawal And Hostility, Nicolas Enzo Mouhsen
Marital Conflict And Male Depression: The Role Of Emotional Withdrawal And Hostility, Nicolas Enzo Mouhsen
Family Perspectives
This literature review investigates the relationship between marital conflict and male depression, focusing on emotional withdrawal and spousal hostility as key contributing factors. Male depression, often underreported due to differences in symptom expression such as anger and irritability, is explored in the context of marital dynamics. Emotional withdrawal, characterized by avoidance behaviors during conflict, is particularly prevalent among men and linked to rigid gender role perceptions. This behavior correlates with increased depressive symptoms and reduced well-being. Additionally, spousal hostility, including verbal aggression and criticism, exacerbates male depression through both the perception of aggression from a partner and self-awareness of hostile …
Probiotic Biogeography In The Neonatal Intestine, Sierra Hansen
Probiotic Biogeography In The Neonatal Intestine, Sierra Hansen
All ETDs from UAB
Neonatal infection remains a leading cause of both neonatal morbidity and mortality worldwide, particularly in preterm infants. Probiotic bacteria have been demonstrated to protect against the development of neonatal intestinal dysbiosis, however, formulations and efficacy vary substantially, highlighting a critical gap in the current understanding of the mechanisms governing probiotic efficacy in this population. This gap is exacerbated by regulatory standards which favor economic expansion over scientific rigor. Furthermore, current studies on probiotic efficacy largely rely on indirect or relative readouts of intestinal bacterial burden. Herein, we directly quantify the probiotic effects of Ligilactobacillus murinus V10 and Escherichia coli Nissle …