Digital Commons Network^™

Public Perceptions Of Universities As Public Entities During The Covid-19 Pandemic Era, Jinho Jung, Laura Barrett, Nicole Olynk Widmar, Mario Ortez

Department of Agricultural Economics Faculty Publications

Higher education institutions are facing challenges in navigating social, cultural, and political issues. The online presence of higher education presents a new set of opportunities and challenges; knowledge, news, and continuing education are increasingly disseminated online. Additionally, the public, student bodies and stakeholders are increasingly looking at reviews or seeking opinions via online and social media to form opinions on institutions. This analysis uses online and social media to analyze and compare perceptions of two public universities in Indiana, namely Purdue University and Indiana University. These two Indiana institutions are located in the same state, allowing for comparisons of public …

Decorin Evokes A Pro-Lysosomal Pathway In Lymphatic Endothelial Cells, Gabriel J. Pascal, Dipon K. Mondal, Sadie Kim, Christopher Xie, Devanarayanan Siva Sankar, Jörn Dengjel, Renato V. Iozzo

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

The lymphatic system is critical to the body's immune and circulatory system, and lymphangiogenesis, the development of new lymphatic vessels from pre-existing ones, is a significant process capitalized upon by cancer during tumorigenesis. Decorin is a small leucine-rich proteoglycan which we have previously shown to be anti-tumorigenic and a suppressor of lymphangiogenesis. We have also shown that decorin exercises its anticancer properties through its ability to evoke autophagy. Through a comprehensive and unbiased proteomic analysis, we explored the implications of decorin exposure on protein expression within mouse lymphatic endothelial cells. We discovered that decorin enriches several protein pathways, notably proteasomal …

Dynamics And Optimal Intervention Strategies In A Shigellosis Transmission Model, Mehmet Gümüs, Shewafera Wondimagegnhu Teklu, Kemal Türk

Mathematical Modelling and Numerical Simulation with Applications

This research explores how water treatment contributes to limiting the transmission of Shigellosis, an infection caused by bacteria from the Shigella genus. A mathematical framework is formulated to evaluate the influence of protective strategies and water purification on the spread of the disease. To confirm the model's biological relevance, its well-posedness is investigated. The basic reproduction number $(\mathfrak{R}_0)$, a critical indicator of disease behavior, is derived using the matrix operator method. Findings indicate that if $\mathfrak{R}_01$, the infection persists, with the endemic equilibrium exhibiting local asymptotic stability. A comprehensive cost-effectiveness analysis reveals that combining environmental protection with water treatment represents …

Diversity Of Butterflies (Lepidoptera) In Kanju, District Swat, Khyber Pakhtunkhwa, Pakistan, Said Miraj Ud Din, Khushbakht Asad, Hamid Ur Rahman, Attiya Iqbal

Journal of Bioresource Management

Butterflies are one of the most beautiful creatures on earth. They belong to the phylum Arthropoda, class Insecta, and order Lepidoptera. Butterflies play an important role in the ecosystem, contributing significantly to pollen transfer. They play an important role in pollination, and their foraging behavior enhances the genetic diversity. Additionally, they also play an important role in the food chain and serve as prey for birds, reptiles, and other insectivore organisms. The current study was conducted to find out the diversity and distribution of butterflies in Kanju district Swat, Khyber Pakhtunkhwa, Pakistan. A total 203 specimens were collected from August …

Current States In Understanding Oligodendroglia-Mediated Neurological Issues In Neurofibromatosis Type 1 (Nf1), Benjamin E Aghoghovwia, Cheng-En Shen, Sabiha Bano, Nandini Shyamala, Alesandra Echeandia Marrero, Khushboo Irshad, Samer Sharafaldin, Nicole M Brossier, Yuan Pan

Faculty, Staff and Student Publications

Neurofibromatosis type 1 (NF1) is among the most common neurogenetic disorders and is associated with an increased risk of developing tumors in the nervous system. Additionally, up to 80% of patients with NF1 experience neurological complications, including deficits in attention, memory, and executive function. Significant effort has been dedicated to studying how NF1 mutations autonomously dysregulate neuronal function. Increasing evidence indicates that NF1 mutations also dysregulate the oligodendroglial lineage that contributes to neurological issues in NF1. Here, we summarize our current understanding of how NF1 mutations impact the oligodendroglial lineage homeostasis and plasticity. We also discuss gaps in knowledge, potential …

Structural Variation Of The Right Coronary Ostium And Its Implications To Cardiac Medicine, Jessica L. Hensley, Joseph X. Anders, Timothy Robinson, William Srinivasan, Donald G. Matz, Ethan L. Snow

The Journal of Integrative Physiology

Introduction: The high oxygen demand of the heart’s myocardium is met via perfusion through the coronary arterial system. During embryological development, the right (RCA) and left (LMCA) coronary arteries fuse onto the aortic root, creating right (RCO) and left (LCO) ostial openings respectively to join the closed circulatory system. Regardless of their widely variable branching patterns, the ability of the RCA and LMCA to perfuse the myocardium initially relies on the functional patency of the coronary ostia. The objective of this study is to examine a unique extra-ostial tissue structure found overlying an RCO and provide a literature-based discussion of …

Early-Life Exposure To Organic Chemical Pollutants As Assessed In Primary Teeth And Cardiometabolic Risk In Mexican American Children: A Pilot Study, Vidya S. Farook, Feroz Akhtar, Rector Arya, Alice Yau, Srinivas Mummidi, Juan Lopez Alvarenga, Alvaro Diaz-Badillo, Roy G. Resendez, John Blangero

Human Genetics Publications

Early-life exposure to organic chemicals (OCs) may influence childhood obesity and associated cardiometabolic risk. These conditions have been shown to disproportionately affect minority populations such as Mexican Americans (MAs). However, information on the impact of organic chemicals on cardiometabolic risk in MA children is limited. Therefore, we conducted a pilot study to assess the extent to which exposure to organic chemicals influences cardiometabolic traits (CMTs) in MA children. We recalled 25 children from a previous study and collected 25 primary teeth from them. Chemical analyses of the teeth were performed using established protocols. Target analytes included acetaminophen (APAP); 3,5,6-trichloro-2-pyridinol (TCPy), …

A Multifaceted Analysis Of The Genetic Origins, Growth, And Invasive Potential Of Introduced Floridian Sugarcane, Indy Hughes

Student Theses and Dissertations

Saccharum spontaneum L., wild sugarcane, is an aggressive invasive species, listed by the USDA as a Federal Noxious Weed (FNW). Despite this, S. spontaneum is used to create hardy, pest-resistant cultivars of domestic sugarcane. All cultivars have a small percentage of wild parentage, but the dosage is low to lessen the chance of inheriting undesirable traits. Saccharum spontaneum’s naturalized presence in Florida has been reported since 1993 and likely escaped from regulated sugarcane breeding facilities. The proximity of S. spontaneum populations to modern cultivars, grown intensively in the state, could potentially increase the risk of invasion. It is imperative to …

Association Between Therapeutic Alliance And Clinical Outcomes In Virtual Telepsychiatry: A Retrospective Analysis Of Data From Talkiatry, Cheryl Person, Nathaniel David Phillips, Kartik Venkatachalam, Georgia Gaveras

Faculty, Staff and Student Publications

Background: Given the increasing demand for accessible mental health services, fully virtual telepsychiatry has become a vital component of modern health care delivery. Therapeutic alliance, the collaborative and affective bond between patients and therapists, is a well-established predictor of clinical outcomes in traditional face-to-face and teletherapy. However, the relationship between therapeutic alliance and clinical outcomes in an outpatient telepsychiatry setting remains less understood.

Objective: Our primary objective was to evaluate the relationship between therapeutic alliance and clinical outcomes for depression and anxiety in an outpatient telepsychiatry practice.

Methods: This retrospective study analyzed data from treatment-seeking adults receiving services from Talkiatry, …

Comparison Of Imaging Based Single-Cell Resolution Spatial Transcriptomics Profiling Platforms Using Formalin-Fixed Paraffin-Embedded Tumor Samples, Nejla Ozirmak Lermi, Max Molina Ayala, Sharia Hernandez, Wei Lu, Khaja Khan, Alejandra Serrano, Idania Lubo, Leticia Hamana, Katarzyna Tomczak, Sean Barnes, Jinzhuang Dou, Qingnan Liang, Rti Team, Maria Gabriela Raso, Ximing Tang, Mei Jiang, Beatriz Sanchez-Espiridion, Annikka Weissferdt, John Heymach, Jianjun Zhang, Boris Sepesi, Tina Cascone, Anne Tsao, Mehmet Altan, Reza Mehran, Don Gibbons, Ignacio Wistuba, Cara Haymaker, Ken Chen, Luisa M Solis Soto

Faculty, Staff and Student Publications

Imaging-based spatial transcriptomics (ST) is evolving as a pivotal technology in studying tumor biology and associated microenvironments. However, the strengths of the commercially available ST platforms in studying spatial biology have not been systematically evaluated using rigorously controlled experiments. We use serial 5 μm sections of formalin-fixed, paraffin-embedded surgically resected lung adenocarcinoma and pleural mesothelioma samples in tissue microarrays to compare the performance of the ST platforms (CosMx, MERFISH, and Xenium (uni/multi-modal)) in reference to bulk RNA sequencing, multiplex immunofluorescence, GeoMx, and hematoxylin and eosin staining data. In addition to an objective assessment of automatic cell segmentation and phenotyping, we …

Aging In Mice Alters Regionally Enriched Striatal Astrocytes, Kay E Linker, Violeta Duran-Laforet, Matthias Ollivier, Xinzhu Yu, Dorothy P Schafer, Baljit S Khakh

Faculty, Staff and Student Publications

Aging affects multiple organs and within the brain drives distinct molecular changes across different cell types. The striatum encodes motor behaviors that decline with age, but our understanding of how cells within the striatum change remains incomplete. Using single-cell RNA sequencing from young and aged mice we identify molecularly distinct astrocyte subtypes. We show that astrocytes change significantly with age, exhibiting downregulation of genes, reduced diversity, and a shift to more homogenous inflammatory transcriptomic profiles. By exploring where striatal astrocyte subtypes are located with single-cell resolution, we map astrocytes enriched in dorsal, medial, and ventral striatum. Age increases inflammatory marker …

The Path To A Green Transition: Just And Inclusive, Nour Elden Tarek Anwr Abd Elshafy

COP30

This paper explores the opportunities and challenges in achieving Just Transition in the agricultural sector, focusing on the critical areas of Climate investments in the field of training and public awareness, policy formulation, and promoting Inclusive sustainable livelihoods for the most affected groups, namely people with disabilities. It highlights the current gaps in Climate investments, the need for inclusive and effective policies, and the importance of ways to achieve just integration to reduce Poverty and unemployment rates. The paper proposes actionable solutions to align financial investments, policy frameworks, and Comprehensive practices with the Paris Agreement goals and Glasgow talks (COP26), …

Operationalising Blue Carbon: Australia's Framework As A Model For Global Nature-Based Climate Mitigation, Chelsea Golding

COP30

Blue carbon ecosystems offer a critical solution to nature-based climate change mitigation. These habitats not only sequester significant amounts of carbon per hectare but also support biodiversity and increase climate resilience for coastal communities. Yet, despite the widespread recognition of these benefits in global climate discussions, most existing carbon sequestration and crediting frameworks remain focused on terrestrial ecosystems and fail to account for the greater variability in marine and costal habitats. This policy gap creates a significant barrier in the capacity for costal carbon sequestration projects to be scaled globally. Australia has addressed this implementation gap at a national level …

Untangling The Roles Of Pulmonary Vagal Afferent Subsets With Inhaled Irritants, Teresa Darcey

USF Tampa Graduate Theses and Dissertations

The sensory nerves in the airways directly regulate critical defenses and indirectly regulate vital gas exchange. Airway function is largely controlled by the autonomic nervous system, and our understanding of its sensory regulation is directly connected to our ability to treat respiratory and cardiovascular pathologies. Airway sensory afferents are heterogeneous with respect to their electrophysiological properties, peptidergic capacity, and stimuli sensitivity, which at least in part dictate some of their various functions. There is evidence that embryological origin impacts reflex function: activation of the neural crest-derived population of sensory afferents has been shown to evoke the cough reflex whereas activation …

Sequence And Phylogenetic Analysis Of Citrus Maxima (Burm.) Merr. From Tomini Bay, Sulawesi Island, Based On The Maturase K Gene, Brenda Febrina Zusriadi, Novri Youla Kandowangko, Febriyanti Febriyanti

Makara Journal of Science

This study was conducted in the coastal area of Tomini Bay, Sulawesi Island, and it focused on Citrus maxima, a plant known for its unique fruit flesh colors, which range from yellow to pink, and its varying leaf stalk wings. The study aimed to analyze the variations in maturase K (matK) sequences, molecular characteristics, and phylogenetic relationships of two C. maxima samples from Tomini Bay compared to other C. maxima and Citrus species using data available in GenBank. The study utilized DNA barcoding with matK molecular markers, followed by phylogenetic tree construction using the maximum likelihood method …

Design And Validation Of The Telemedicine Comfort Tool, Stephanie Amador

Doctoral Dissertations and Projects

In recent years, telemedicine has become a valuable resource to improve communication between patients and health care providers. There are many benefits to telemedicine, but they are only realized if patients and healthcare providers can establish a comforting and trusting relationship between them. Although Telemedicine has positively impacted health care, it is only successful if patients and health care providers can communicate effectively in the virtual environment. This quantitative study developed and validated the Telemedicine Comfort Tool among members of Veterans on Deck. The Telemedicine Comfort Tool is a survey instrument with the goal of measuring the comfort level of …

Bridging The Gap: Does Individual Crossfit Open Performance & Event-Type Influence Crossfit Games Team Performance?, Anthony J. Mack

Doctoral Dissertations and Projects

Individual CrossFit Open (CFO) and CrossFit Games (CFG) performance factors, including physiological metrics, sex, competitive experience, and workout pacing strategies, are well established; however, there is a gap in the literature comparing CFO and CFG team performance. The purpose of this study was to examine whether individual CFO scores and event category (i.e., monostructural, gymnastics-skill, weightlifting, or work capacity) influence a team's final score at the CFG. Teams (n = 196) from the 2018-2024 CFG seasons were included in data collection. Data from CFO workouts (n = 28) and CFG team events (n = 62) were extracted from games.crossfit.com. Scores …

Tv Versus Video Games: Their Distinctive Effects On Adolescent Behavior And Academic Achievement, Faiaz Rahman, Kathy L. Schuh

Mid-Western Educational Researcher

The current paper uses data collected from a publicly available, nationally representative data set to examine the effects of TV viewing and video gaming on adolescent behavioral problems and cognitive achievement. Results revealed that extended hours of TV viewing were associated with greater anxiety/depression and antisocial problems. On the other hand, extended hours of video gaming were associated with higher reading comprehension scores. Differing effects of TV viewing and gameplay by an individual’s sex was also found during the analysis. It is also important to note that the opposite effects that the two media has on outcomes, indicate that, although …

Chacahoula 2025, Volume 92, Alayna Pellegrin

Chacahoula

The 2025 issue of Chacahoula includes December 2024 and May 2025 graduating classes, as well as stunning photography student life on the banks of Bayou Desiard. With features covering students, faculty, and staff, this year's time capsule preserves an academic year in the life of the University of Louisiana at Monroe.

Poziotinib For Egfr Exon 20-Insertion Nsclc: Clinical Efficacy Of The Phase 2 Zenith Trial And Differential Impact Of Egfr Exon 20 Insertion Location On Sensitivity, Xiuning Le, Jacqulyne P Robichaux, Monique Nilsson, R S K Vijayan, Ashwin Ravichandran, Jia Wu, Yasir Y Elamin, Lingzhi Hong, Jun Pei, Jun He, Sonia Patel, Hibiki Udagawa, Sriramvignesh Mani, Chang Woon Jang, Jeffrey M Clarke, Nishan Tchekmedyian, Jonathan W Goldman, Mark Socinski, Gajanan Bhat, Sharon Leu, Veronica Bunn, Zhenqiang Su, Sylvie Vincent, John W Lawson, Jason B Cross, John V Heymach

Faculty, Staff and Student Publications

EGFRex20 insertions (EGFRex20ins) can be classified as near- and far-loop based on the insertion location, however, the impact of location on responses to various EGFR tyrosine kinase inhibitors (TKIs) is poorly understood. In vitro studies show that afatinib, poziotinib, and zipalertinib more potently inhibited near-loop than far-loop insertions, whereas mobocertinib has similar IC50 in both groups. Molecular dynamics simulations reveal that near-loop insertions have multiple conformational states and lower transitional energy than far-loop insertions. ZENITH20 trial cohort 1 (NCT03318939) evaluates poziotinib in EGFRex20 NSCLC patients (n = 115) and demonstrates an objective response rate of 14.8% (95% Confidence …

An Updated Checklist Of The Mammals Of Türkiye, Mustafa Sözen, Faruk Çolak

Turkish Journal of Zoology

Between 1982 and 2025, the number of extant wild mammal species worldwide rose from 4170 to 6706. The Turkish mammal fauna also showed a similar trend, with the number of mammal species listed for Türkiye rising from 89 to 173 in just 33 years, from 1989 to 2021. A shift in species numbers like this calls for regular updates to Türkiye’s mammal species lists as well as the preparation of new checklists. Apart from changes in the number of species, numerous taxonomic changes and rearrangements also lead to changes in mammal lists. We arranged an updated mammal checklist by reviewing …

A Comparison Between Phalangeal Skeletochronology And Cephalic Parietal Rings In Lizards, Marco A.L. Zuffi, Roberto Sacchi, Marcello Mezzasalma, Maria José Amaral, Miguel Angel Carretero, Fabio Maria Guarino

Turkish Journal of Zoology

The well-defined, layered organization of the cephalic scales in many lacertilians could offer a noninvasive alternative for estimating the individual age of these vertebrates. This study aimed to validate the method of age determination based upon the cephalic scale rings in the genus Podarcis, comparing it to phalangeal skeletochronology, a widely used and highly reliable indirect method for estimating the age of ectotherm vertebrates. We analyzed individuals of P. bocagei (n = 48), P. muralis (n = 16) and P. siculus (n = 8). For each individual, we compared the number of cephalic layers with the number of lines of …

Association Of Genetic Scores Related To Insulin Resistance With Neurological Outcomes In Ancestrally Diverse Cohorts From The Trans-Omics For Precision Medicine (Topmed) Program, Chloé Sarnowski, Yixin Zhang, Farah Ammous, Lincoln M. P. Shade, Daniel Dicorpo, Xueqiu Jian, Donna K. Arnett, Thomas R. Austin, John Blangero, Joanne E. Curran

School of Medicine Publications

To better characterize the potential biological mechanisms underlying insulin resistance (IR) and dementia, we derive cross-population and population specific polygenic scores [PSs] for fasting insulin and IR-related partitioned PSs [pPSs]. We conduct a cross-sectional study of the associations of these genetic scores with neurological outcomes in >17k participants (36% men, mean age 55 yrs) from the Trans-Omics for Precision Medicine (TOPMed) program (50% Non-Hispanic White, 23% Black/African American, 21% Hispanic/Latino American, and 4% Asian American). We report significant negative associations (P <  0.002) of the cross-population (P = 1.3 × 10-5) and European (PEA = 3.0 × 10-8) fasting insulin PSs with total cranial volume, and of a metabolic syndrome European PS with general cognitive function (BEA = -0.13, PEA = 0.0002) and lateral ventricular volume (BEA = 0.09, PEA = 0.002). We identify suggestive negative associations (P <  0.007) of metabolic syndrome and obesity pPSs with general cognitive function, and of lipodystrophy pPSs with total cranial volume. A higher genetic predisposition to IR is associated with lower brain size, and a genetic predisposition to specific IR-related type 2 diabetes subtypes, such as metabolic syndrome and mechanisms of IR mediated through obesity and lipodystrophy, is potentially involved in cognitive decline.

Multiscale Modelling Of Eg5: Structural Insights Into Microtubule Interactions, Atp Hydrolysis, And Allosteric Inhibition Mechanisms, Soundarya Priya Alexandar Ms

Theses and Dissertations

The mitotic kinesin EG5 is essential for spindle bipolarity and accurate chromosome segregation during cell division, making it a validated anti-cancer target. Unlike conventional microtubule-targeting agents, EG5 inhibitors offer mitosis-specific action, reducing neurotoxicity. Although inhibitors targeting EG5’s allosteric site-I have been extensively studied, mechanistic insights into inhibition at site-II, and their combined effects, remain underexplored. This thesis systematically investigates the structural and dynamic mechanisms underlying EG5 function and its inhibition using an integrative computational approach.

Conformational analysis, coarse-grained dynamics, all-atom molecular dynamics simulations, and protein network analysis were performed on EG5 motor domain structures and EG5-microtubule complexes. Results show that …

Functional Role Of Cysteine Residues In Vtlr Of Agrobacterium Tumefaciens, Suravi Islam

Theses and Dissertations

Agrobacterium tumefaciens is a soil-dwelling plant pathogen known for transferring DNA to host plants through a type IV secretion system. Central to its virulence and cellular regulation is the LysR-type transcriptional regulator, VtlR, which controls processes including biofilm formation, motility, tumorigensis, and small RNA expression. Although VtlR’s regulatory role is established, the specific functions of its conserved cysteine residues have only recently begun to be explored. This study investigates VtlR’s four cysteines (C144, C236, C244, and C273) through site-directed mutagenesis and a combination of phenotypic assays and transcriptional profiling. Phenotypic assays confirmed that C144 and C273 are important for proper …

Machine Learning For Genetic Expression, Jennifer M. Fowler

Student Theses and Dissertations

The publication of the human genome in 1994 launched a computational biology revolution. Despite subsequent advances in sequencing and computing technology, the research community lacks robust and reproducible tools for interpreting differential expression of genes. Modern high-throughput genome sequencing and high-density arrays allow unprecedented computational analysis of genetic profiles. These developments combined with the rise artificial intelligence and machine learning powered by unprecedented amounts of data present new opportunities in bioinformatics. A novel gene ranking method, AUCg, is presented and applied to genetic expression data from patients with multiple myeloma. The AUCg method is compared to popular Bioconductor tools, and …

Barriers To Achieving Graduated Responsibility: Preparing Pathology Residents For Independent Practice, Bronwyn H. Bryant, Balaram Puligandla, Hailey L. Gosnell, Kristen Johnson, Stephanie Barak, Mary P. Berg, Satyapal Chahar, John M. Childs, Julie Katz Karp, Amanda Lofgreen, Cindy B. Mccloskey, Barbara E. C. Knollmann-Ritschel, Kristie L. White, W. Stephen Black-Schaffer

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Allowing pathology residents to practice with high levels of autonomy helps prepare them for independent practice. The Accreditation Council for Graduate Medical Education (ACGME) recently added to the core requirements that residents must have opportunities to perform assigned clinical responsibilities under oversight supervision-defined as review and feedback after care is delivered. To understand the current state of resident autonomy, pathology residency programs were surveyed (32 responses) about the highest level of supervision achieved by senior residents for common pathology tasks, as well as the most significant barrier to achieving oversight supervision for each task. Each task was assigned a "supervision …

Investigating Potential Alzheimer's Disease Therapies Through An Agent-Based Model Of Impaired Microglia Metabolismmodeling Impaired Microglia Metabolism, Cheyenne Ty, Abigail Penland, John Gerving, Martin Mendoza-Ceja, Megan Pratt, Kamila Larripa

Spora: A Journal of Biomathematics

Alzheimer’s disease is the leading cause of dementia globally and is marked by amyloid-β plaque accumulation, decreased brain pH, disrupted metabolism, and increased permeability of the blood-brain barrier. Microglia, the resident immune cells of the central nervous system, are essential for maintaining brain homeostasis and are critically involved in the progression of AD. While microglia can initiate protective immune responses to injury and disease, dysregulated microglial metabolism may contribute to the exacerbation of Alzheimer's pathology. To investigate potential therapeutic strategies, we developed an agent-based model simulating the effects of exercise and metabolic enhancement on dysfunctional microglia. Our findings suggest that …

Investigating Soil Co2 Flux Among Varying Soil Types During Inundation Conditions, Jennifer Volk, Arya Patel

The Pegasus Review: UCF Undergraduate Research Journal

Land use change has contributed to the increase of carbon dioxide (CO₂) release, exacerbating global greenhouse gas (GHG) emissions. CO₂ is also naturally produced in the soil via microbial respiration which breaks down soil organic matter (SOM). Several studies have investigated factors affecting CO₂ flux from soils, but few have compared CO₂ flux from a range of soil types under controlled conditions with varying water levels. This study subjected intact soil cores from six different soil types to varied periods of inundation and dry events using the same water and timing. During each event, CO …

Comparative Study For Channel Pairing In Noma Ofdm- Cdma System, Hazem H. El-Banna, Nelly M. Shafik

Mansoura Engineering Journal

Orthogonal Multiple Access such as OFDM technique became inadequate scheme since it provides limited spectral efficiency and limited number of users. In addition to Orthogonal Multiple Access (OMA), Non-Orthogonal Multiple Access (NOMA) technique is applied in 5th generation of mobile communications that enhances both spectral efficiency and capacity with high Quality of Service (QoS). In this paper, three techniques were combined NOMA, OFDM, and CDMA in order to have optimal system performance in the presence of worst fading channel situations; fast frequency selective Rayleigh multi-path fading channel. The main contribution of this paper is the novel channel pairing technique introduced …