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Fisheries Research Report No. 351: Ecological Risk Assessment For The Western Australian Southern Nearshore Fish Resource, Kimberley A. Smith, Brett Crisafulli, Amber Quinn, Bianca Brooks, Gabby E. Mitsopoulos, Daniel Yeoh May 2025

Fisheries Research Report No. 351: Ecological Risk Assessment For The Western Australian Southern Nearshore Fish Resource, Kimberley A. Smith, Brett Crisafulli, Amber Quinn, Bianca Brooks, Gabby E. Mitsopoulos, Daniel Yeoh

Fisheries Research Reports

On 3 December 2024, the Department of Primary Industries and Regional Development (DPIRD, the Department) convened an ecological risk assessment (ERA) of the fisheries that access the Southern Nearshore Fish Resource (Resource). This Resource comprises a range of temperate fish species including Australian herring, Australian salmon, whiting, garfish, tailor and sandy sprat.

This document contains the results of the ERA as well as the background information used to support the ERA risk scoring process. This includes an overview of the Western Australian commercial, recreational and charter fisheries that access the Resource.


Dairy Digest, Legan...Dairy 2024-2025, Department Of Dairy And Food Science May 2025

Dairy Digest, Legan...Dairy 2024-2025, Department Of Dairy And Food Science

Dairy Digest

This is the 2025 Dairy Club Digest. The Diary Club Digest is published annually by the South Dakota State University Dairy Club.
The Digest contains information and news about the activities and members of the SDSU Dairy Club for the academic year 2023 - 2024.


Large Mammal Herbivores As Gardeners Of Tropical Forest Ecosystems, Kathryn Garner May 2025

Large Mammal Herbivores As Gardeners Of Tropical Forest Ecosystems, Kathryn Garner

Student Scholarship

Ecosystems worldwide are experiencing changes in structure and function as populations of fauna decline and experience local extinctions (Torres-Romero et al. 2020). Due primarily to their body size, large mammal herbivores (LMHs) are disproportionately prone to extinction from human activities such as agricultural expansion, deforestation, and anthropogenic climate change (Pringle et al. 2023). Additionally, as the number of domesticated LMHs (i.e. cattle, pigs, etc.) continue to increase in both density and distribution, their wild counterparts are continually displaced, resulting in increased competition for resources and an increased risk of disease transmission between domestic to wild species (Pringle et al. 2023; …


Examining Sustainable And Regenerative Viticultural Practices In The Rheinhessen Wine Region Of Germany, Claire Hoffmann May 2025

Examining Sustainable And Regenerative Viticultural Practices In The Rheinhessen Wine Region Of Germany, Claire Hoffmann

CISLA Senior Integrative Projects

No abstract provided.


Unraveling The Antiviral Mechanisms Of Bat Cells: Processing Of Genomic Rnas By Dicer In Bat Cells Limits Sars-Cov-2 Replication, Iyanuoluwani Owolabi May 2025

Unraveling The Antiviral Mechanisms Of Bat Cells: Processing Of Genomic Rnas By Dicer In Bat Cells Limits Sars-Cov-2 Replication, Iyanuoluwani Owolabi

Dissertations

Bats are reservoirs for numerous viruses that cause serious diseases in other animals and humans. Several mechanisms are proposed to contribute to the tolerance of bats to these pathogens. This study investigates the response of bat cells to double-stranded RNA generated by SARS-CoV-2 replication. Here, we found the involvement of Dicer in the processing of viral genomic RNAs during SARS-CoV-2 infection. Examining RNA sequencing of infected cells, small-interfering RNA (siRNA)-like fragments were found derived from viral RNAs. Depletion of Dicer showed a reduction in these RNAs and an increase in viral loads suggesting unlike other mammals, bats may use Dicer …


Joe Rogan And The Manosphere In The Age Of Modern Misogyny, Alexandra Klocker May 2025

Joe Rogan And The Manosphere In The Age Of Modern Misogyny, Alexandra Klocker

CSB and SJU Distinguished Thesis

Much scholarly research analyzes extreme misogynistic language in “manosphere” forums, due to their connections to radicalization and violence. However, less attention has been given to the prevalence of such content in mainstream media, such as podcasts. The Joe Rogan Experience (JRE) podcast, a prominent and influential platform, has been praised for its wide-ranging discussions but critiqued for fostering and amplifying harmful ideologies, including misogyny. Despite its controversy, limited research has explored how pre-existing misogynistic rhetoric in online communities might shape or influence the content of JRE episodes. This study examines how misogynistic language and themes proliferate in JRE episodes through …


Ghosts In Glass: Ghost Crabs (Ocypode Quadrata) As Judges Of Glass Sand For Coastal Restoration, Emily Parrish May 2025

Ghosts In Glass: Ghost Crabs (Ocypode Quadrata) As Judges Of Glass Sand For Coastal Restoration, Emily Parrish

Poster Presentations

Coastal erosion is heavily impacting coastal ecosystems across the Gulf. For instance, the state of Louisiana loses a football field worth of land every 100 minutes (Couvillion, 2017). The drastic loss of coastline highlights the dire need for restoration in the Northern Gulf Coast. An unexpected solution to this sediment loss may solve two major environmental issues at once by diverting millions of tons of glass waste from entering America’s landfills each year. By crushing glass to create sand and gravel for coastal restoration, we may generate a consistent and sustainable source of substrate. Our goal is to determine the …


The Effects Of Incubation Humidity On Broiler Chicks, Claire Caples May 2025

The Effects Of Incubation Humidity On Broiler Chicks, Claire Caples

Animal Science Undergraduate Honors Theses

Leg health issues are a welfare problem in commercial broiler chickens and an economic issue for the broiler industry. Broilers exhibiting leg abnormalities show altered gait, reduced ability to access resources, and increased lameness incidence. These leg health issues can result from many animal and environmental factors during incubation and post-hatch. Incubation strategies may contribute to the development of leg health issues, and recent research has increased focus on incubation factors affecting embryonic development and health and welfare post-hatch. Thus, the objective of this study was to evaluate the effect of high (80%), low (55%), and ideal (65%) humidity on …


Developing Protective Measures To Reduce The Incidence Of Bacterial-Induced Chondronecrosis With Osteomyelitis In Broiler Chickens, Alexa L. Thomas May 2025

Developing Protective Measures To Reduce The Incidence Of Bacterial-Induced Chondronecrosis With Osteomyelitis In Broiler Chickens, Alexa L. Thomas

Animal Science Undergraduate Honors Theses

Bacterial Chondronecrosis with Osteomyelitis (BCO) lameness is a significant animal welfare and food safety issue affecting the commercial broiler industry in the United States and worldwide. Bacteria can translocate from the respiratory system and/or the gastrointestinal tract into the bloodstream, eventually settling in bone microfractures leading to necrosis and BCO lameness.

This study evaluated the effects of Probiotic 1 and Probiotic 2 on the incidence of BCO lameness in broiler chickens. Probiotic 1 was applied as a spray on Day 1-old chicks, while Probiotic 2 was administered prophylactically (orally in feed) from Day 1 to Day 56. Birds were assigned …


Fisheries Occasional Publication No.148 - Aquaculture Of Seaweed In Western Australia: Policy Principles Relating To Licences And Exemptions For The Aquaculture Of Seaweed In Western Australia, Department Of Primary Industries And Regional Development, Western Australia May 2025

Fisheries Occasional Publication No.148 - Aquaculture Of Seaweed In Western Australia: Policy Principles Relating To Licences And Exemptions For The Aquaculture Of Seaweed In Western Australia, Department Of Primary Industries And Regional Development, Western Australia

Fisheries Occasional Publications

of aquaculture, and clarifies the process and information required to assess applications for aquaculture licences, leases and exemptions for seaweed aquaculture in WA.

Development of principles will support decision-making for the take of wild seaweed and for the grant or variation of aquaculture licences for seaweed aquaculture.


Investigating Regulation Of Neutrophil-Mediated Inflammation In Mycoplasma Pneumoniae Infection, Nathan D. Velazquez May 2025

Investigating Regulation Of Neutrophil-Mediated Inflammation In Mycoplasma Pneumoniae Infection, Nathan D. Velazquez

University Scholar Projects

No vaccine exists for Mycoplasma pneumoniae (Mp) infections, largely due to the

gap in understanding in the virulence and immunopathogenesis of this bacterium.

We have recently demonstrated that neutrophils are maladaptive in the context of

Mp infection, and drive disease severity while also impairing bacterial clearance.

Furthermore, we observed that B cells play a regulatory role in limiting disease

severity by modulating neutrophilic inflammation. We investigated this

phenomenon further to elucidate the mechanisms by which B cells regulate

neutrophilic inflammation. We utilized a monoclonal antibody to deplete B cells

during Mp infection and found that B-cell-depleted mice had elevated neutrophil …


Differences Between Media And Industry Professionals’ Views On Welfare Issues At Equine Racetracks In The United States, Olivia Burris May 2025

Differences Between Media And Industry Professionals’ Views On Welfare Issues At Equine Racetracks In The United States, Olivia Burris

Honors College Theses

The objective of this project was to see if there was a difference in views between lay publications in the media and industry professionals regarding welfare issues occurring at equine racetracks. This study focused on the issues of drug usage and racing-related injuries in racehorses. This project examined current lay publications versus surveys of industry professionals discussing the specific welfare issues. These lay publications were reviewed and summarized for comparison to the industry professionals’ responses to the survey.


Frontier Healthscapes: Competing Narratives Of Disease, Environment, And Wellbeing In Early Minnesota, Aidan Reynolds May 2025

Frontier Healthscapes: Competing Narratives Of Disease, Environment, And Wellbeing In Early Minnesota, Aidan Reynolds

Geography Honors Projects

Across settler societies, health narratives were shaped by evolving tensions between lay and expert knowledge, frameworks of disease causation, and perceptions of the environment as both a source of health and a threat. In the decades following Euro-American settlement (1860-1900), Minnesota became a focal point for these debates, with its landscape fostering complex and competing narratives on health, wellbeing, and disease. This paper explores how public health discourse developed in Minnesota through the perspectives of institutions, the public, and economic interests. Combining environmental history with critical discourse analysis of archival materials, this study examines shifts within the Minnesota State Board …


An Analysis Of Cellular And Tissue Function Of Lipin In Drosophila Melanogaster, Judah Christian Scott May 2025

An Analysis Of Cellular And Tissue Function Of Lipin In Drosophila Melanogaster, Judah Christian Scott

Graduate Theses and Dissertations

Regulation of energy expenditure and energy storage is a key characteristic of life. Numerous enzymes play a crucial role in regulating energy metabolism. Lipins are a highly conserved family of proteins that function in both lipid synthesis and gene regulation. In the glycerol-3 phosphate pathway, lipins act as a phosphatidate phosphatase (PAP) producing diacylglycerol. In gene regulation, lipins act as transcriptional co-regulators of metabolic genes. The enzymatic PAP activity occurs in the cytoplasm; however, for lipins to function as gene regulators, they must translocate into the nucleus. Nuclear translocation is facilitated by the nuclear localization signal (NLS) within the protein. …


Bacterial Chondronecrosis With Osteomyelitis In Broilers: Etiology And Selected Mitigation Measures, Khawla Saud Alharbi May 2025

Bacterial Chondronecrosis With Osteomyelitis In Broilers: Etiology And Selected Mitigation Measures, Khawla Saud Alharbi

Graduate Theses and Dissertations

Bacterial chondronecrosis with osteomyelitis (BCO) is the predominant cause of lameness in broiler chickens. It mainly impacts broiler production and animal welfare, causing substantial financial losses accounting for 1- 2% due to bird condemnations at the marketing age. Remediating BCO lameness disease demands investigating its causes using appropriate models and evaluating preventive measures, such as enhancing epithelial tissue health and tight junction integrity in the digestive and respiratory tract, strengthening immune functions, and improving bone strength. Therefore, the objectives of this dissertation were to 1) study predisposing factors for BCO lameness by investigating the effects of deoxynivalenol (DON) and fumonisin …


Genomic Analysis Of The Lyme Disease Vector Across Virginia’S Spatial Expansion Front, Amy Jablonski May 2025

Genomic Analysis Of The Lyme Disease Vector Across Virginia’S Spatial Expansion Front, Amy Jablonski

Honors Theses

Lyme disease is the most common vector-borne disease in the United States and is expanding with rising incidence in Virginia . This study investigates populations of lxodes scapularis across Virginia using RAD-seq to analyze SNPs from ticks collected in seven Virginia counties and four U.S. states as references . Results show a clear genetic split between western and eastern Virginia ticks . These results follow previously noted patterns in regional differences in Lyme disease risk.


Using A Process Evaluation In Extension Programming: Takeaways For Teams, Cristina Connolly, Jeantyl Norze, Stacey F. Stearns May 2025

Using A Process Evaluation In Extension Programming: Takeaways For Teams, Cristina Connolly, Jeantyl Norze, Stacey F. Stearns

Journal of Human Sciences and Extension

Health fields use process evaluations to measure how closely an intervention aligns with its intended delivery. Despite their potential for improving Cooperative Extension programming and impacts, process evaluations are not widely used outside the medical sciences. We adapted the process evaluation framework for Extension use. The components assess project components such as content, dose delivered, dose received, and reach, as well as moderating factors such as quality of delivery, participant responsiveness, complexity, facilitation strategy, recruitment, and context. The modified process evaluation framework was used to assess an Extension project in the Northeast region of the U.S. Extension teams in the …


Prevalence Rates Of Tetb, Teta, And Tetm Tetracycline Resistance Genes In Environmental Escherichia Coli Isolates From Local Waterways, Caris Cianelli May 2025

Prevalence Rates Of Tetb, Teta, And Tetm Tetracycline Resistance Genes In Environmental Escherichia Coli Isolates From Local Waterways, Caris Cianelli

Honors Projects

The purpose of this study was to determine the prevalence rates of the tetracycline resistance genes tetA, tetB, and tetM in environmental Escherichia coli isolates. Samples were from both an urban and an agricultural waterway were filtered and incubated with Coliscan™ medium to differentiate for fecal coliforms. The resulting colonies were streaked onto EMB and then TSA plates to ensure isolation and presence of E. coli. All media used were supplemented with 10 µg/mL tetracycline in order to maintain selective pressure on the isolates. DNA from the isolates was then extracted and PCR was run using tetA, tetB, and tetM …


Characterizing The Medial Forebrain Bundle In Adolescents With Anhedonic Depression, Tina Nguyen May 2025

Characterizing The Medial Forebrain Bundle In Adolescents With Anhedonic Depression, Tina Nguyen

Biological Sciences Undergraduate Honors Theses

Adolescent depression has quickly grown in prevalence, yet the underlying neuropathology remains poorly understood. Anhedonia–the diminished ability to experience pleasure–is a core symptom of melancholic depression. Early identification of biomarkers associated with anhedonic depression could help mitigate the severity of the disorder by enhancing treatment efficacy. Blunted functionality of the nucleus accumbens (NAcc), the reward center of the brain, and abnormal dopaminergic activity in the ventral tegmental area (VTA) have both been linked to depression. Furthermore, glutamatergic input from the hypothalamus modulates the VTA which in turn, downregulates dopamine release in the NAcc. However, there is limited evidence supporting that …


The Impact Of Maternal Age On The Expression Of Transgenerational Plasticity In Daphnia Pulicaria, Calvin Nguyen May 2025

The Impact Of Maternal Age On The Expression Of Transgenerational Plasticity In Daphnia Pulicaria, Calvin Nguyen

2025 Spring Honors Capstone Projects - Archive

Transgenerational plasticity refers to heritable, non-genetic changes in phenotype that persist across multiple generations and can enhance offspring survivability in variable environments. In Daphnia, increasing maternal age has been associated with maladaptive plasticity. To investigate this relationship, six clones were collected from two Wisconsin lakes and acclimated to laboratory conditions through a common garden rearing process. For each clone, ten replicates were generated and evenly divided between young (clutches 2–4) and old (clutches 5–8) maternal age groups. Offspring were exposed to three dietary treatments for three experimental generations: one fed only green algae, one fed only cyanobacteria (a nutritionally …


Rnai Pathway Homeostasis Is Essential For Longevity In C. Elegans., Sejal Dulal May 2025

Rnai Pathway Homeostasis Is Essential For Longevity In C. Elegans., Sejal Dulal

2025 Spring Honors Capstone Projects - Archive

RNA interference (RNAi) is a gene regulatory mechanism that is conserved across all animal species, including humans and the microscopic nematode, Caenorhabditis elegans. Many studies have identified the RNAi pathway factors and dissected the regulatory mechanisms of RNAi pathways, but there is little understanding of how the RNAi pathways themselves are regulated. Previously, Rogers and Phillips identified a feedback loop mediated by a pair of small RNA sensors, Sensor of siRNAs-1 (sosi-1) and eri-6[e-f], embedded within the genomic locus of a small RNA biogenesis factor, ERI-6/7. In this feedback motif, loss of small RNA-mediated silencing of …


Elucidating The Role Of Transposable Element Derived Gene, Dplg3, In Drosophila Melanogaster, Kaisy A. Martinez May 2025

Elucidating The Role Of Transposable Element Derived Gene, Dplg3, In Drosophila Melanogaster, Kaisy A. Martinez

2025 Spring Honors Capstone Projects - Archive

A big fraction of most eukaryotic genomes is comprised of transposable elements (TEs). TEs are mobile genetic sequences often causing deleterious effects as they increase in copy number. On rare occasions, TEs can undergo molecular domestication, where the TE proteins are co-opted by the host to serve cellular functions. In Drosophila melanogaster, domestication from PIF/Harbinger TEs has resulted in five Drosophila PIF-Like Genes (DPLG1-4 and 8). This study focuses on investigating the function of DPLG3. In DPLG3 knock out lines, DPLG3-KO, a fraction of the progeny shows an abnormal gonad phenotype. We sought to confirm …


Assessing The Prevalence Of Ehrlichia Spp. In Ticks Associated With Canids In Arkansas, Eva J. Berryhill May 2025

Assessing The Prevalence Of Ehrlichia Spp. In Ticks Associated With Canids In Arkansas, Eva J. Berryhill

Animal Science Undergraduate Honors Theses

Canine ehrlichiosis is a disease that is commonly seen in dogs. In previous studies, the southeastern part of the United States has been identified as an area of high prevalence. Arkansas was included in the region where the prevalence is high. Changes in climate, household income, and tick population were identified as factors contributing to this high prevalence. Canine ehrlichiosis is caused by three Ehrlichia spp., which are E. canis, E. ewingii, and E. chaffeensis. Ticks are responsible for transmitting the disease, specifically R. sanguineus, D. variabilis, and A. americanum. For this study, the goal was to determine the prevalence …


Utilizing 16s Ribosomal Rna Sequencing To Identify Bacterial Species Colonizing Lame Birds With Bacterial Chondronecrosis With Osteomyelitis, Kara Hoover May 2025

Utilizing 16s Ribosomal Rna Sequencing To Identify Bacterial Species Colonizing Lame Birds With Bacterial Chondronecrosis With Osteomyelitis, Kara Hoover

Animal Science Undergraduate Honors Theses

Broiler chicken lameness has become prevalent in recent years due to high growth rates in broilerchickens. Bacterial chondronecrosis with osteomyelitis (BCO), the main cause of lameness, is characterized by necrosis of femoral and tibial heads in affected birds. Heavier birds are more susceptible to mechanical stress in these regions, which results in microfractures, leading to lameness. BCO lameness poses huge financial pressure to the poultry industry, as 14-50% of flocks can become affected during outbreaks. The purpose of this experiment was to identify bacterial species present in birds with BCO lameness. A total of 1,560 chicks were randomly distributed into …


The Effect Of 1,25-Dihydroxyvitamin D3 Supplementation On Humoral Immunity Against Bacterial Chondronecrosis With Osteomyelitis Lameness In Broiler Chickens, Bailey Herberger May 2025

The Effect Of 1,25-Dihydroxyvitamin D3 Supplementation On Humoral Immunity Against Bacterial Chondronecrosis With Osteomyelitis Lameness In Broiler Chickens, Bailey Herberger

Animal Science Undergraduate Honors Theses

Bacterial chondronecrosis with osteomyelitis (BCO) lameness, the most predominant locomotive illness in fast-growing broilers, causes substantial animal well-being issues and affects broiler production, leading to huge financial losses. Several strategies, including feed supplementations using organic trace minerals, vitamin D, probiotics, and prebiotics, have been utilized to alleviate BCO lameness incidences in broiler chickens. Previous studies have indicated that feeding an additive of Panbonis®-G-1,25(OH)2D3 from Solanum glaucophyllum containing 1 µg/kg G-1,25(OH)2D3 to broilers for the first 28 days of their production cycle reduced BCO lameness by more than 50%. In this study, we …


Uncovering The Evolutionary Origins Of Neo-Sex Chromosomes In The Insect Family Membracidae, Mary Kumah May 2025

Uncovering The Evolutionary Origins Of Neo-Sex Chromosomes In The Insect Family Membracidae, Mary Kumah

2025 Spring Honors Capstone Projects - Archive

This research explores the evolution of the neo-XX/XY sex chromosome system of Amblyophallus exaltatus, a treehopper insect in the family Membracidae. Neo-XX/XY sex chromosome systems can evolve from an XX/X0 sex chromosome system via fusion events between the X chromosome and an autosome. Although cytological work has indicated the presence of a neo-XX/XY system within A.exaltatus, the chromosomal identity of the fused autosome and the molecular drivers behind this chromosomal fusion remain poorly understood. By performing a coverage analysis with whole genome sequence data, the parts of the A.exaltatus genome that fused with the X chromosome will be better …


First Specimen-Based Record Of Barbonymus Schwanefeldii (Bleeker, 1854) (Teleostei: Cyprinidae) From Laguna De Bay, Philippines, Kent Elson S. Sorgon, Marjorie Juliana L. Martinez, Andrei Justin F. So, Mariko Franccesca R. Aboganda, Jazreen Nicole G. Parungo, Aeris Johanne G. Poricallan, Keona Tiffany B. Prieto, Mellissa Jewel S. Magday, Alexa Charlize Dc Geronimo, Ma. Vianca Julia E. Anupol, Derreck O. De Leon May 2025

First Specimen-Based Record Of Barbonymus Schwanefeldii (Bleeker, 1854) (Teleostei: Cyprinidae) From Laguna De Bay, Philippines, Kent Elson S. Sorgon, Marjorie Juliana L. Martinez, Andrei Justin F. So, Mariko Franccesca R. Aboganda, Jazreen Nicole G. Parungo, Aeris Johanne G. Poricallan, Keona Tiffany B. Prieto, Mellissa Jewel S. Magday, Alexa Charlize Dc Geronimo, Ma. Vianca Julia E. Anupol, Derreck O. De Leon

Biology Faculty Publications

The introduction of non-native fish species in the freshwater ecosystems of the Philippines presents a clear threat to native ichthyofauna, making verified reports of such introductions all the more critical. Through the examination of a collected specimen and anecdotes from fisherfolk and social media, we present here the first records of the occurrence of the tinfoil barb, Barbonymus schwanefeldii (Bleeker, 1854), in Laguna de Bay, Luzon Island, Philippines. This represents the addition of another non-native fish species in this lake, which is increasingly becoming dominated by non-native and invasive fishes that have been intentionally or accidentally introduced. Monitoring landed fish …


Mechanisms Of Particulate Hexavalent Chromium-Induced Inhibition Of Homologous Recombination Repair: Targeting The Bcdx2 Complex Considered Through A One Health Perspective., Aggie W. Brownell May 2025

Mechanisms Of Particulate Hexavalent Chromium-Induced Inhibition Of Homologous Recombination Repair: Targeting The Bcdx2 Complex Considered Through A One Health Perspective., Aggie W. Brownell

Electronic Theses and Dissertations

Lung cancer remains the leading cause of cancer death, often linked to smoking. However, smoking alone does not account for all cases. Exposure to environmental metals like hexavalent chromium [Cr(VI)] also contributes to lung cancer. Cr(VI) causes lung cancer by inducing chromosome instability (CIN), an early hallmark of its carcinogenic mechanism. While it has been established that Cr(VI) induces chromosome instability, the precise mechanisms underlying the chromosome instability are poorly understood. This dissertation investigates the mechanisms of carcinogenesis associated with zinc chromate, a particularly potent particulate form of hexavalent chromium. Studies show Cr(VI) induces DNA double-strand breaks and impairs the …


A Review On Treatment, Prevention, And Research Of Worldwide Parasitic Disease: Toxoplasmosis, Hannah Skinner May 2025

A Review On Treatment, Prevention, And Research Of Worldwide Parasitic Disease: Toxoplasmosis, Hannah Skinner

All Theses

Toxoplasmosis is a worldwide, yet often overlooked, parasitic disease caused by the protozoan parasite, Toxoplasma gondii. The parasite is capable of infecting humans and almost all warm-blooded vertebrates. Over a million people are infected in the United States with toxoplasmosis each year. Most infections are asymptomatic but severe cases can lead to vision impairment, neurological disorders, and congenital birth defects. T. gondii is transmitted through undercooked meat, infected feline feces, or contaminated water and soil. The burden of T. gondii infection is most notable in livestock, felines, and immunocompromised humans. Despite being a widespread disease, toxoplasmosis is neglected in …


Effects Of Novel Dopamine D4 Receptor-Targeted Compounds On Locomotor Activity And Anxiety-Like Behavior In Male And Female Sprague Dawley Rats, Samantha Alyse Walkow, Noah A. Ivak, Daniel Chandler, John Tkaczynski, Thomas M. Keck, Comfort A. Boateng, Eleni Papadopoulos, Barry D. Waterhouse, Rachel L. Navarra May 2025

Effects Of Novel Dopamine D4 Receptor-Targeted Compounds On Locomotor Activity And Anxiety-Like Behavior In Male And Female Sprague Dawley Rats, Samantha Alyse Walkow, Noah A. Ivak, Daniel Chandler, John Tkaczynski, Thomas M. Keck, Comfort A. Boateng, Eleni Papadopoulos, Barry D. Waterhouse, Rachel L. Navarra

Rowan-Virtua Research Day

The consequences of modulating subtypes of G protein coupled dopamine receptors are broadly studied for their role in decision making behavior, specifically in situations involving uncertain risk and reward. The actions of dopamine D4 receptors (D4Rs) on these complex processes are the least understood, particularly due to a lack of available compounds with suitable selectivity for D4Rs. Further, current research often fails to evaluate how modulating specific dopamine receptor subtypes may affect locomotor activity and anxiety-like behavior as confounding factors prior to assessing their function in behavioral assays of higher order decision making. The goal of the current study was …