Digital Commons Network^™

Bioactive Constituents And Pharmacological Activities Of Curcuma Zedoaria: A Mini-Review, Abdulmutalib Allaq, Muneer M. Saleh Mohammed Saleh Alsayadi, Mustapha Salihu, Hasan M. Agha, Amena Hassan Hassan Gheeth, Fatimah Salim, Norrizah Jaafar Jaafar Sidik

AUIQ Complementary Biological System

Curcuma zedoaria Rosc. (white turmeric) is a rhizomatous medicinal plant in the Zingiberaceae family, widely used in traditional Asian medicine. In recent years, increasing scientific attention has focused on its diverse pharmacological properties and bioactive constituents. This mini review summarises current knowledge of the phytochemical composition and biological activities of C. zedoaria, with particular emphasis on its antimicrobial, antioxidant, anti-inflammatory, and anticancer effects. Phytochemical investigations using analytical techniques such as GC–MS and HPLC have revealed the presence of numerous bioactive compounds, including sesquiterpenes (example, germacrone, curzerenone, and curdione) and curcuminoids, which contribute to its therapeutic potential. Experimental studies demonstrate …

Mapping The Void In Electric Vehicle (Ev) Adoption Research: Uncovering Lack Of Socio-Economic Study In The Global South, Satvik Pandey, Rahul Tiwari, Rajat Soni

Mansoura Engineering Journal

Electric Vehicles (EVs) are considered an effective contemporary alternative to Internal Combustion Engine (ICE) vehicles. Research in the domain of EV is being conducted globally across a variety of fields; among them, our study explored research on consumer adoption. Going through the bibliometric analysis of the data taken from the Scopus database, what came to our attention is the minimal amount of work that is done on understanding consumers of EVs. From the literature, we found that consumer preferences are shaped through the influence of several parameters related to EVs, and this influence varies according to the consumer’s socio-economic and …

Breeding For Diverse Color And Protein Quality In Popcorn And Sweet Corn, Jonathan Niyorukundo

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

Sweet corn and popcorn are important crops consumed globally as vegetable and snack, respectively. They are deemed healthy foods due to high fiber and carotenoid contents, especially in yellow varieties. Commercial varieties are optimized for high-yielding agronomics, and previous efforts were made to improve specific macro- and micronutrient contents. Both sweet corn and popcorn have poor protein quality due to the inadequate essential amino acids such as lysine and tryptophan. Moreover, commercial varieties are predominantly yellow, thereby offering no diversity of other maize colors, which are potentially healthier and more appealing to the consumer. In this project, we sought to …

Expanding The Fossil Record Of Hippopotamodon (Suidae, Artiodactyla) From The Hasnot Area, Siwalik, Pakistan, Muhammad Ilyas, Rana Mehroz Fazal, Sayyed Ghyour Abbas, Misbah Faiz, Kiran Aftab, Abdul Ghaffar, Khizar Samiullah, Luke Holbrook

STEM Student Research Symposium Posters

The suid genus Hippopotamodon with its type species H. sivalense, is well known from Upper Miocene deposits in Eurasia. Its taxonomic history has been characterized by considerable instability, including early misassignments to genera such as Sus and Potamochoerus, and subsequent reclassifications involving Propotamochoerus, Dicoryphochoerus, and Microstonyx. This confusion primarily resulted from an overreliance on variable dental and canine morphology. Subsequent systematic revisions attempted to resolve these issues by proposing synonymies among these taxa, although debate has continued regarding the relationship between Hippopotamodon and Microstonyx. Recent work supports the synonymy of these taxa based on shared diagnostic features across Eurasian material. …

Using The Flexon Approach To Rnai To Identify Essential Genes That Affect Gonadal Development In C. Elegans, Joyce S. Lefevers

Undergraduate Theses

To elucidate the molecular role of essential genes in the gonadal development of Caenorhabditis elegans (C. elegans) it is necessary to utilize specialized molecular techniques such that the phenotypic effects of gene knockdown can be studied while the viability of the organism is preserved. Shaffer and Greenwald (2022) developed the floxed exon (flexon), a tool that improves upon previous approaches to spatiotemporal control of gene expression. The flexon subunit is made up of an artificial exon with a stop cassette flanked by artificial introns which, when inserted into a gene of interest, prevents the expression of that gene. …

Lake Sturgeon (Acipenser Fulvescens) Growth And Longevity Estimated From Adult Capture-Mark-Recapture Data, Edward A. Baker, Scott F. Colborne, Nancy A. Auer, Kim T. Scribner, Douglas L. Larson, Andrew S. Briggs, Ronald M. Bruch, Margaret H. Stadig, Michael C. Donofrio

Michigan Tech Publications

Effective fishery management policy depends on accurate life-history data, particularly for harvested species. Longevity is a core life-history trait that is directly related to annual survival and lifetime reproductive potential, but fish longevity is generally not well documented, particularly for long-lived species. We used capture-mark-recapture data spanning 44 years as an alternative method to estimate sex-specific adult lake sturgeon (Acipenser fulvescens) average annual growth and longevity for five populations in the Laurentian Great Lakes. We determined individual fish average annual growth and fit population and sex-specific exponential lines for average annual growth as a function of fish length at initial …

A Functional Nutrition Literature Review For Brain Fog And Adhd-Like Symptoms In Adults, Natalie Elisani Aldahondo-Matos

Department of Nutrition Student Projects

Attention-deficit/hyperactivity disorder (ADHD) and ADHD-like symptoms, such as difficulty concentrating, mental fatigue, and problems with executive functioning, are increasingly recognized in adults. Although medication is commonly used to manage ADHD, there is growing interest in whether nutrition may also play a role in supporting brain function and attention. Several nutrients involved in brain health including omega-3 fatty acids, vitamin B12, magnesium, iron, and choline  have been suggested as potential contributors to cognitive performance and attention. However, the research examining the connection between diet and ADHD symptoms is still limited and sometimes shows mixed results.

The purpose of this project was …

Microarray Analysis Of Human Abdominal Aortic Aneurysm With Emphasis On Cardiovascular Genes Revealed Differentially Expressed Genes, Song Lu, Li Ping Li, John V. White, Xiaoying Zhang, Ifeyinwa Nwaneshiudu, Adaobi Nwaneshiudu, Nectaria Ntaoula, John Gaughan, Dimitri S. Monos, Wan-Lu Lin, Charalambos C. Solomides, Emilia L. Oleszak, Chris D. Platsoucas

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

BACKGROUND/AIM: We examined gene expression profiles in abdominal aortic aneurysm (AAA) lesions vs. normal aortas by cDNA microarray and real-time quantitative reverse-transcriptase polymerase chain reaction (qRT-PCR).

MATERIALS AND METHODS: Phosphorus (³²P)-labeled cDNA from AAA specimens (mean AAA size 6.65 cm) and normal aortas were hybridized with a 588-gene microarray primarily of the cardiovascular system. The results were validated by qRT-PCR.

RESULTS: A total of 35 out of the 588 genes were differentially expressed, with either log₂ ratio of AAAs/controls ≥1 (upregulated; 20 genes) or ≤-1 (downregulated; 15 genes) in AAA lesions vs. normal aorta, and …

The Spatial Distribution Of Coccidia In Arkansas Freshwater Snails, Julia R. Pye, Taylor M. Fiedor, Jason M. Post, Kyle D. Gustafson

Create@State

Coccidia are obligate, intracellular parasites that infect the digestive tracts of many animals and cause coccidosis, which can result in vomiting, diarrhea, and in severe cases, death. At broader scales, the disease contributes to substantial economic losses in agriculture. Our study examined the distribution of Pfeifferinella ellipsoides, a coccidian parasite in freshwater snails. Based on previous research, we hypothesized that (1) there will be statistically significant spatial clustering in northern Arkansas and (2) the parasite will be found exclusively in two snail genera, Physa and Planorbella. We sampled 17 snail species and surveyed feces for oocysts from 1,920 snails and …

Solarvale: Exploring Australian Ecology And Culture Through Serious Game Design, Ping-I (Adam) Ho, Elliot Birch

Imaginings: creative practice and inquiry

This research examines how a serious game (Gee, 2007): Solarvale: Tale of the Sun Root (Birch et al., 2024), developed by students from SAE University College addresses the importance of ecological conservation and cultural awareness specifically in relation to the Australian landscape. While some Australian serious games, such as Catchment Detox (2008), Paperbark (2018), and Bleached Az (2019) engage with similar themes, few titles integrate storytelling with interactive ecological environments and cultural awareness in a way that encourages players to reflect on their own role and actions—which is the central focus of Solarvale. Drawing on the concepts from serious …

Beyond Attachment: Endolysosomal Determinants Of New World Arenavirus Entry And Fusion, Cassandra E. Thompson

Arts & Sciences Graduate Student Theses and Dissertations

Arenaviruses are enveloped, negative-sense RNA viruses maintained in rodent reservoirs and transmitted to humans through exposure to aerosolized rodent excreta, where they can cause severe and sometimes fatal disease. The geographic distribution of arenaviruses reflects the range of their rodent reservoirs, resulting in the classification into Old World and New World groups, with New World arenaviruses further subdivided into clades A–D. Viral entry is the first step of infection and a major determinant of host range, tissue tropism, and zoonotic potential. Further, viral entry is a tightly regulated, multistep process that couple’s receptor engagement with intracellular trafficking and pH-dependent membrane …

Garlic Breath And Beads Of Sweat: The Effects Of Garlic And Chili Peppers On The Growth And Ph Of Streptococcus Mutans., Lena Pitzer

Honors Projects

The purpose of this project is to provide a quantifiable and repeatable measurement of how the presence of garlic and chili pepper during the growth of a carious dentine strain of Streptococcus mutans affects the growth of the strain and surrounding pH level.This research project examines two possible alternative agents, garlic and chili peppers, due to the known antimicrobial effects of their active components, allicin and capsaicin. Prepared garlic and chili extracts were used during disk diffusion to assess and measure the zones of inhibition. The anticipated results are that there will be inhibition present with both the garlic and …

Environmental Counseling As A Proposed Discipline And Its Associated Implications And Uses, Alexandria Rion

Honors Projects

Individuals interact with their environment daily, and whether they realize it or not, these interactions can impact their health. Understanding the health impacts associated with the environment is important to human health at both an individual and population level. I am proposing a new field of environmental counseling that would incorporate principles from a variety of practices into one comprehensive discipline that can be used to promote public health. By studying populations that have had negative environmental exposures and looking at their outcomes, I was able to apply principles of environmental counseling to help determine if it would in fact …

Evaluation Of Sirna-Mediated Knockdown Of Heat Shock Protein 16.2 In Adult Acropora Cervicornis, Edward P. Gniffke, Benjamin D. Young, Keir J. Macartney, Michael S. Studivan, Ian C. Enochs, Erin E. Easton

School of Earth, Environmental, & Marine Sciences Faculty Publications

Acropora cervicornis is a critically endangered Caribbean coral species facing a precipitous decline due to disease and thermal bleaching. To combat the loss of ecologically important reef-building corals, novel molecular approaches can be used to understand mechanisms of resilience and ultimately provide a means to modulate coral performance. In this study, we tested a recently developed method for gene knockdown in adult corals that utilizes short interfering RNAs (siRNAs) and the RNA interference pathway. The Heat Shock Protein 16.2 (HSP16.2) gene in fragments of adult A. cervicornis was targeted for knockdown using a single siRNA construct. RT-qPCR analysis of HSP16.2 …

Impacts Of Supplemental Fat In Finishing Diets On Digestibility, Performance, Carcass Outcomes, Meat Quality And Methane Production Of Feedlot Cattle, Anna Marie Kobza

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

Rising costs and fluctuating availability of supplemental fats has led to increased interest in alternative fat sources or feed additives that might improve utilization of supplemental fat in feedlot diets. Two separate experiments were conducted to evaluate alternative strategies to overcome high fat prices. The first experiment was a metabolism study, conducted to evaluate digestion parameters of supplemental fat sources with or without LYSOFORTE Extend. The objectives of this experiment were to evaluate LYSOFORTE Extend in beef finishing diets containing a saturated fat source (tallow) and unsaturated fat source (corn oil). Duodenally and ruminally fistulated steers were fed diets containing …

Unh Fillable Agriculture Water Inspection Record Template, Wendy A. Johnecheck

UNH Cooperative Extension

No abstract provided.

Tlr2 Activation Enhances Inflammatory Signaling And Accelerates Cyst Growth And Renal Fibrosis In Polycystic Kidney Disease Mice, Aiping Wei, Yang Zhang, Yu Xu, Jaden Schneider, Nicholas Detterman, Xiaoyun Shu, Tyler Gregersen, Maximo Nahas Folch, Yong Li, Shibiao Chen, Yan Zhang

Michigan Tech Publications

Polycystic kidney disease (PKD), the most common inherited kidney disorder, is characterized by progressive cyst growth and eventual organ failure. Although aberrant innate immune activation is a recognized contributor to PKD progression, the underlying molecular mechanisms remain incompletely defined. Here, we showed that Pkd1 deletion increased TLR2 and MyD88 mRNA expression in renal epithelial cells, indicating enhanced innate immune priming. In vivo, administration of Pam3CSK4 (PAM), a synthetic TLR2 agonist, preferentially amplified pro-inflammatory and pro-fibrotic responses in Pkd1^RC/RC mice compared with wild-type controls, despite inducing similar signaling responses in vitro. Acute PAM treatment for one week rapidly enhanced NF-κB …

Cross-Sectional Associations Of Metabolically Healthy Obesity, Lifestyle Factors, And Steatotic Liver Disease In Adults From The Fels Longitudinal Study, Ariana L. Garza, Audrey C. Choh, John Blangero, Cici X. Bauer, Stefan A. Czerwinski, Miryoung Lee

School of Medicine Publications

Objective: To examine the associations of metabolic health and obesity phenotypes with liver fat accumulation and hepatic steatosis in adults. Methods: We analyzed 676 non-Hispanic white adults (18–95 years; 55.8% female) from the Fels Longitudinal Study using a cross-sectional design. Participants were classified into metabolically healthy normal weight (MHNW), metabolically healthy obesity (MHO), metabolically unhealthy normal weight (MUNW), and metabolically unhealthy obesity (MUO) phenotypes. Metabolically unhealthy status was defined as the presence of ≥1 metabolic dysfunction, consistent with prior epidemiological definitions; secondary analyses using ≥2 were also performed. Obesity was defined using DXA-derived body fat percentage. Liver fat (%) was …

2026 - The Thirtieth Annual Symposium Of Student Scholars

Symposium of Student Scholars Program Books

The full program book from the 30th Annual Symposium of Student Scholars, held on April 22-24, 2026. Includes abstracts from the presentations and posters.

The Impacts Of Wing-Flashing By Northern Mockingbirds On Foraging, Parental Care, And Reproductive Success, Anna Starman, Hayley Ponn

Science Seminar

Foraging efficiency may be enhanced by flashing patches of white wing and tail feathers and has been documented in several avian species. Northern Mockingbirds (Mimus polyglottos, NOMO) exhibit this "wing-flashing" (WF) behavior while foraging, during displays, and in response to predators. In NOMOs, WF has been hypothesized to increase foraging success, but previous findings are inconclusive. To further investigate the biological role(s) of WF behavior in NOMOs, the ventral surface of white primary feathers of male NOMOs were artificially darkened and the foraging and provisioning rates of undarkened (control) males and their mates were compared. While foraging, undarkened males performed …

Effects Of Limb Dominance On Dopaminergic Neurodegeneration In A 6-Ohda Rat Model Of Parkinson’S Disease Assessed By Immunoblotting, Jasin Aziz Porshia, Deanna Chaialee, Dipesh Pokharel, Kala Venkiteswaran, Thyagarajan Subramanian, Dilshan Beligala

ONU Student Research Colloquium

Effects of Limb Dominance on Dopaminergic Neurodegeneration in a 6-OHDA Rat Model of Parkinson’s Disease Assessed by Immunoblotting

Jasin Porshia^a , Deanna Chaialee^a , Dipesh Pokharel^b,c , Kala Venkiteswaran^{b, c, d} , Thyagarajan Subramanian^{b, c, d}, Dilshan Beligala^a

^aDepartment of Biological Sciences, Ohio Northern University, Ada, OH, USA

^bDepartment of Neurosciences and Psychiatry, The University of Toledo College of Medicine and Life Sciences, Toledo, OH, USA

^cDepartment of Neurology, The University of Toledo College of Medicine and Life Sciences, Toledo, OH, USA

^dDepartment of Neurology, Howard University, Washington, DC, …

A Single Administration Of Psilocybin Is Ineffective In Reversing Ptsd-Like Sequelae In A Rat Model Of Stress-Enhanced Fear Learning, Kylie M. King, Marisa J. Savini, Noelle M. Molnar, Evelynn J. Schneider, Savannah E. Straub, Joe Parker, Lillianna P. Puppel, Aleece K. Al-Olimat, Allison M. Bach, Phillip R. Zoladz

ONU Student Research Colloquium

Single treatments with psychedelics produce rapid, long-lasting antidepressant effects. Psychedelics may also exert anxiolytic effects and be useful in treating more complex psychiatric conditions, such as PTSD. However, less is known about the impact of these agents on PTSD-related symptoms. Thus, we aimed to determine whether a single administration of psilocybin could reverse PTSD-like sequelae induced by stress-enhanced fear learning in rats. Sprague-Dawley rats were placed in Context A (circular, white conditioning box) and exposed to several uncontrollable footshocks (Stress) or no footshocks (No Stress). The next day, the rats were placed in Context B (square conditioning box with clear …

Impact Of Caffeine On Participant Memory For A Stressful Experience And The Development Of Intrusive Memories, Jaycee L. Kirkland, Kaylina R. Mcclenen, Natalina E. Porter, Sarah M. Wood, Julia Gross, Madilyn E. Paphanchith, Kelsey M. Siereveld, Jasmine Ic Ifeakanwa, Caeden M. Gurganus, Koen N. Suzelis, Aiden J. Farrell, Boyd R. Rorabaugh, Phillip R. Zoladz

ONU Student Research Colloquium

Most individuals consume caffeine on a daily basis. Research has shown that caffeine stimulates the release of glucocorticoids and catecholamines and can enhance cognition. Caffeine also amplifies stress-induced increases in arousal and aggravates PTSD-like symptoms. Thus, we examined the impact of caffeine on memory for a stressful experience and intrusive memories related to that experience. Undergraduate students ingested caffeine or a placebo. Thirty minutes later, they were exposed to the Trier Social Stress Test (TSST; stress condition) or friendly-TSST (f-TSST; control condition), both of which were designed to enable participant memory for the experiences to be quantified. In each condition, …

Program And Proceedings, The Nebraska Academy Of Sciences 1880–2026: 146th Anniversary Year, One Hundred-Thirty-Sixth Annual Meeting

Nebraska Academy of Sciences: Programs and Proceedings

Program and abstracts of the proceedings for the Nebraska Academy of Sciences 136th annual meeting, 2025

Sessions

Aeronautics and Space Science

Anthropology

Biological and Medical Sciences

Earth Sciences

Ecology, Sustainability, and Environmental Science

Physics and Engineering

General Poster Session

2026 Maiben Lecture: Shifting Extremes: Understanding Nebraska’s Changing Climate and Preparing for What Lies Ahead, Deborah Bathke

2026 Friends of Science Awards: Julie Shaffer and Irina Filina

2026 C. Bertrand and Marian Othmer Schultz Colleaguate Schoalrship Award: Piper Ryschon and Bryce Reeson

In Memoriam: Paul Royster

Evaluating Drug Use Through Examination Of Local Water Sources: Drug Concentrations Within Biota Systems, Madeleine Freyhof

Honors Projects

Understanding drug usage based on drug concentrations found within biota samples grown in different concentrations of cocaine and benzoylecgonine. Drug policy then can be potentially based on how drug concentrations display drug usage for a specific community.

Cultivating Curiosity Across Academic Audiences: Biology And Evidence-Based Science Communication, Nathan D. Forbes

Whittier Scholars Program

Effective Science Communicators must speak to a variety of audiences, with varying quantities of prior interest and qualities of background knowledge. The purpose of this paper was to engage differing audiences in scientific learning. This was done through a hypothetical newsletter made up for four different segments exploring a variety of topics in biology. Each segment intends to speak to a different audience with a different level of interest and/or educational level. Simplifying or analogizing without sacrificing the statistical basis of this project was of paramount importance. In the two segments targeted towards younger audiences, the primary focus was on …

How Pollinator Populations Can Impact Chronic Disease Risk, Kylee Cubbison

Honors Projects

This project investigates how pollinator populations can impact chronic disease risk. Pollinator populations are declining, which can have serious implications for human health. Declining pollinator populations can limit healthy food production and affordability. Poor nutrition is a major risk factor for most chronic diseases. Less healthy food available for people to consume can negatively impact diets and increase the risk of developing chronic diseases. This project aims to address a potential gap in research existing on this specific topic regarding pollinator populations and human chronic disease risk. A brochure targeted towards educating the general public on this topic was created …

Development Of A Preclinical Model That Can Be Used To Test Novel Therapeutics For The Treatment Of Mild And Moderate Traumatic Brain Injury, Hayden Anderson

Honors Theses

Traumatic Brain Injury (TBI) occurs when a foreign object induces damage to the skull and brain through a forceful blow or whiplash. It is one of the most frequent injuries in the United States, with approximately 250,000 cases of different levels occurring annually. It is well known that severe TBIs can result in persistent physical, cognitive, and socioeconomic consequences and the timing of treatment following this injury can play a critical role in the ultimate outcome. It would be beneficial to develop a safe therapeutic that could be administered rapidly after impact and improve the recovery of the patient. However, …

From Bench To Bedside: Unraveling The Role Of Sarm1 In Chronic Human Neurodegenerative Disease, Caitlin Dingwall

Arts & Sciences Graduate Student Theses and Dissertations

Axon degeneration (AxD) is an early and often causative event in many neurodegenerative diseases, yet no treatments exist to halt the breakdown of axons. In healthy axons, the axon survival factor NMNAT2 inhibits SARM1, the central executioner of programmed axon degeneration. NMNAT2 is a highly labile protein produced in the soma and trafficked into the axon. Nerve injury blocks axonal transport and leads to rapid depletion of axonal NMNAT2, causing NMN buildup and NAD+ loss. Recent breakthroughs led to the discovery that SARM1 is activated by an increase in the NMN to NAD+ ratio. While the SARM1 axon degeneration pathway …

The Pam-1 Aminopeptidase Does Not Protect Against Ptl-1 Mediated Neurodegeneration In C. Elegans., Ethan E. Schuff

Honors College Theses

Debilitating neurodegenerative conditions are increasingly prevalent in our aging population, yet treatment options remain limited. Though neurodegenerative diseases vary in pathophysiology and clinical manifestations, these diseases are related to one another in that many involve misfolded proteins. Tau is a member of the microtubule-stabilizing MAPT/MAP2/MAP4 family, and misfolded tau proteins form the neurotoxic aggregates called neurofibrillary tangles (NFTs) found in the brains of patients with Alzheimer's disease and other neurodegenerative diseases. Designing a study to elucidate the neurotoxic role of tau is difficult because other MAPs may have compensatory mechanisms which confound study data. Caenorhabditis elegans (C. elegans) …