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Breaks In Longitudinal Elastic Fibers Of Human Femoropopliteal Arteries, Elham Zamani

UNO Student Research and Creative Activity Fair

Breaks in Longitudinal Elastic Fibers of Human Femoropopliteal Arteries

Elham Zamani1, Majid Jadidi1

1 Department of Biomechanics, University of Nebraska Omaha, Omaha, NE

Introduction: Elastin is a major protein in the body with half-life >50 years. It is thought that elastic fibers are formed before the postnatal period. In the femoropopliteal artery (FPA), the main artery in the leg, longitudinal elastic fibers are present in External Elastic Lamina (EEL). Our team has studied more than 1000 cadaveric human FPA and has noticed that there are big breaks in their longitudinal elastic fibers in some subjects. Our goal in this work …

Influence Of Particle Size And Zeta Potential In Treating Highly Coloured Old Landfill Leachate By Tin Tetrachloride And Rubber Seed, Siti Fatihah Ramli, Hamidi Abdul Aziz, Fatehah Mohd Omar, Mohd Suffian Yusoff, Herni Halim, Mohamad Anuar Kamaruddin, Kamar Shah Ariffin, Yung-Tse Hung

Civil and Environmental Engineering Faculty Publications

Old leachate normally has a low organic compound content, poor biodegradability and is hard to biologically treat. The efficacy of tetravalent metal salts as a coagulant and the application of a natural coagulant as a flocculant in landfill leachate treatment is still inconclusive. Hence, this study aimed to evaluate the potential application of tin tetrachloride (SnCl4 ) as the main coagulant and the rubber seed (Hevea brasiliensis) (RS) as the natural coagulant aid as the sole treatment in eradicating highly coloured and turbid stabilised landfill leachate present at one of the old local landfills in Malaysia. The standard jar test …

An Interactive Game With Virtual Reality Immersion To Improve Cultural Sensitivity In Healthcare, Paul J. Hershberger, Yong Pei, Timothy N. Crawford, Sabrina M. Neeley, Thomas Wischgoll, Dixit B. Patel, Miteshkumar M. Vasoya, Angie Castle, Sankalp Mishra, Lahari Surapaneni, Aman A. Pogaku, Aishwarya Bositty, Todd Pavlack

Computer Science and Engineering Faculty Publications

Purpose: Biased perceptions of individuals who are not part of one’s in-groups tend to be negative and habitual. Because health care professionals are no less susceptible to biases than are others, the adverse impact of biases on marginalized populations in health care warrants continued attention and amelioration. Method: Two characters, a Syrian refugee with limited English proficiency and a black pregnant woman with a history of opioid use disorder, were developed for an online training simulation that includes an interactive life course experience focused on social determinants of health, and a clinical encounter in a community health center utilizing virtual …

Challenges Of The Industrial Revolution Era 1.0 To 5.0 : University Digital Library In Indoensia, Merlin Apriliyanti, Ilham M

Library Philosophy and Practice (e-journal)

This study explains the development of the world of libraries to establish a very close relationship with the world of information technology. For this reason, facilities and infrastructure are needed to facilitate data and information retrieval quickly and accurately. Facing the challenges of the Industrial Revolution 5.0 era by utilizing information technology, libraries must also adapt to the times. Because the library has an important role, among others, as a source of information and the development of knowledge. Used libraries are still conventional to be converted into digital libraries. In essence, this development represents the desire of library users for …

Implementation Of Secondary And Tertiary Treated Wastewater In Concrete Manufacturing, Amany G. Micheal Prof., Haidy Abd El Salm, Gouda Ghanem Prof.

Centre for Advanced Materials

Water scarcity is a problem that faces many regions. In a developing and arid country like Egypt, the need for freshwater is exponentially increasing. This research is an evaluation of the recycled wastewater to be used in concrete manufacturing. The treated wastewater is blended with potable water with percentages of 25%, 50%, and 100%. The mixture of the two types of water is used in concrete mixing and curing. Control specimens with pure potable water are cast for comparison. The setting time for Ordinary Portland Cement is tested using the different water mixes. The hardened concrete is tested in compression …

Optimization Of A Novel Nipam-Based Thermoresponsive Copolymer For Intramuscular Injection As A Myoblast Delivery Vehicle To Combat Peripheral Artery Occlusive Disease, Quentin R. Klueter

Master's Theses

There is a need for a minimally invasive delivery method to enable cell therapies to combat peripheral artery occlusive disease (PAOD) in end stage patients. Myoblasts show promise as a cell mediated therapy but warrant an improved delivery method to increase cell retention in the region of interest because of their adherent nature, relative to previously used BM-MNC’s that are non-adherent. Contemporary issues with achieving successful cell therapies of vasculature can be mainly characterized by the lack of clinical translation from promising animal studies and absence of cell delivery scaffolding. Naturally, polymers have been widely experimented with as grafts to …

Impact Of Primary Myoblasts On Macrophage Polarization In-Vitro, Olivia Welch

Master's Theses

Peripheral artery disease (PAD) is characterized by the development of atherosclerotic plaques on arterial walls, leading to the narrowing of blood vessels, resulting in ischemia in the downstream tissue. In the United States, 12% of the adult population is affected by PAD and its related symptoms. Current surgical revascularization techniques can be effective in part of the patient population, but there is a need for other options. Alternatively, collateral blood vessels, or natural bypass arteries, enlarge to increase blood flow to the ischemic tissue in a process called arteriogenesis, which has been studied as a therapeutic option. Cell-based therapies, such …

Groundwater Level Modeling With Machine Learning: A Systematic Review And Meta-Analysis, Mojtaba Sadegh

Civil Engineering Faculty Publications and Presentations

Groundwater is a vital source of freshwater, supporting the livelihood of over two billion people worldwide. The quantitative assessment of groundwater resources is critical for sustainable management of this strained resource, particularly as climate warming, population growth, and socioeconomic development further press the water resources. Rapid growth in the availability of a plethora of in-situ and remotely sensed data alongside advancements in data-driven methods and machine learning offer immense opportunities for an improved assessment of groundwater resources at the local to global levels. This systematic review documents the advancements in this field and evaluates the accuracy of various models, following …

Technical Analysis Of Thanos Ransomware, Ikuromor Ogiriki, Christopher Beck, Vahid Heydari

College of Science & Mathematics Departmental Research

Ransomware is a developing menace that encrypts users’ files and holds the decryption key hostage until the victim pays a ransom. This particular class of malware has been in charge of extortion hundreds of millions of dollars every year. Adding to the problem, generating new variations is cheap. Therefore, new malware can detect antivirus and intrusion detection systems and evade them or manifest in ways to make themselves undetectable. We must first understand the characteristics and behavior of various varieties of ransomware to create and construct effective security mechanisms to combat them. This research presents a novel dynamic and behavioral …

Chemical Thermodynamics—A Practical Wonderland, Rubin Battino, Trevor M. Letcher

Chemistry Faculty Publications

Chemical thermodynamics is frequently thought of as being a hard subject and quite abstract. In fact, it is one of the most practical of subjects when you consider that the field of chemical engineering (responsible for endless useful applications) is effectively applied chemical thermodynamics. In this essay, examples of these applications are given, especially with respect to sustainability. The essay first considers the limits of thermodynamics and the constraints put on it in terms of the rigorous definitions of the principal function’s energy, entropy, and Gibbs energy.

Hsp90 Inhibitors Modulate Sars-Cov-2 Spike Protein Subunit 1-Induced Human Pulmonary Microvascular Endothelial Activation And Barrier Dysfunction, Ruben Manuel Luciano Colunga Biancatelli, Pavel Solopov, Betsy W. Gregory, Yara Khodour, John D. Catravas

Bioelectrics Publications

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has caused more than 5 million deaths worldwide. Multiple reports indicate that the endothelium is involved during SARS-Cov-2-related disease (COVID-19). Indeed, COVID-19 patients display increased thrombophilia with arterial and venous embolism and lung microcapillary thrombotic disease as major determinants of deaths. The pathophysiology of endothelial dysfunction in COVID-19 is not completely understood. We have investigated the role of subunit 1 of the SARS-CoV-2 spike protein (S1SP) in eliciting endothelial barrier dysfunction, characterized dose and time relationships, and tested the hypothesis that heat shock protein 90 (HSP90) inhibitors would prevent and repair such injury. S1SP …

Water Chemistry, Exposure Routes, And Metal Forms Determine The Bioaccumulation Dynamics Of Silver (Ionic And Nanoparticulate) In Daphnia Magna, Emma Lesser, Fatima Noor Sheikh, Mithun Sikder, Marie Noële Croteau, Natasha Franklin, Mohammed Baalousha, Niveen S. Ismail

Engineering: Faculty Publications

Treatment wetlands utilize various physical and biological processes to reduce levels of organic contaminants, metals, bacteria, and suspended solids. Silver nanoparticles (AgNPs) are one type of contaminant that can enter treatment wetlands and impact the overall treatment efficacy. Grazing by filter-feeding zooplankton, such as Daphnia magna, is critical to treatment wetland functioning; but the effects of AgNPs on zooplankton are not fully understood, especially at environmentally relevant concentrations. We characterized the bioaccumulation kinetics of dissolved and nanoparticulate (citrate-coated) 109Ag in D. magna exposed to environmentally relevant 109Ag concentrations (i.e., 0.2–23 nmol L−1 Ag) using a stable isotope as a tracer …

Bone And Cartilage Compression Simulator, Karoline M. Wucherer, Benjamin A. Parmentier, Thomasina E. Hinkle

Biomedical Engineering

A device was developed that delivers mechanical loads to bone and soft tissue samples under physiological conditions to aid in the research of tissue engineering bone and cartilage. To begin the design process, a Network Diagram and Gantt Chart were produced to create a general timeline for the project to follow. This allowed us to measure our progress and determine what effects (if any) delays could have on our project.

Microwave Hyperthermia Application With Bioimplant Single Slot Coaxial Antennadesign For Mouse Breast Cancer Treatment, Ahmet Ri̇fat Görgün, Cem Baytöre, Selçuk Çömlekçi̇, Mehmet İbrahi̇m Tuğlu, Adnan Kaya

Turkish Journal of Electrical Engineering and Computer Sciences

In this study, a novel animal model for the breast cancer treatment which contains hyperthermia is proposed. For this main purpose a low cost, interstitial, bioimplant antenna by short ended single slot design is proposed to heat the cancerous tissues. Both the theoretical background of the proposed system and the simulation and measurement results of antenna design are presented. An artificial tissue phantom model has been created under laboratory conditions and then the utility of the proposed antenna has been tested on this model. Artificial tissues have been heated by 25W to (41-44 ? C) in a short time like …

Photonic Integrated Circuit-Assisted Optical Time-Domainreflectometer System, Mehmet Cengi̇z Onbaşli

Turkish Journal of Electrical Engineering and Computer Sciences

Optical time-domain reflectometers (OTDR) are photonic systems that consist of an interrogator, a receiver and a fiber optical cable and have applications in telecommunications, security, environmental monitoring, distributed temperature and strain sensing. Since OTDR systems are bulk optical setups that consume multiple Watts of power, have large mass and volume footprint and are vulnerable to thermal drift, deployment of OTDR systems in the field is expensive, complicated and may not necessarily yield accurate sensing results. Thus, a compact, low-power, inexpensive and thermal drift-free OTDR system needs to be developed for improving the accuracy and the viability of OTDR in the …

Design And Manufacture Of Electromagnetic Absorber Composed Of Boricacid-Incorporated Wastepaper Composites, Ali̇ İhsan Kaya, Ahmet Çi̇fci̇, Fi̇li̇z Kirdioğullari, Mesud Kahri̇man, Osman Çerezci̇

Turkish Journal of Electrical Engineering and Computer Sciences

With the effect of technological advances, the use of electrical and electronic devices has increased dramatically in recent years. Wireless technologies and related applications are mostly preferred for the communication of these devices with each other. Thus, people are easily exposed to electromagnetic waves in daily life. The extensive global use of these devices raises the question of their possible biological effects on human health. Also, electromagnetic waves influence the functioning of a nearby device. In this study, an electromagnetic absorber based on boric acid (5, 10, 20, and 30 wt%) added wastepaper was developed. Copper (Cu) and aluminum (Al) …

Enhanced Immunoprecipitation Techniques For The Identification Of Rna-Binding Protein Partners: Igf2bp1 Interactions In Mammary Epithelial Cells, Saja A. Fakhraldeen, Scott M. Berry, David J. Beebe, Avtar Roopra, Celia M. Bisbach, Vladimir S. Spiegelman, Natalie M. Niemi, Caroline M. Alexander

Mechanical Engineering Faculty Publications

RNA-binding proteins (RBPs) regulate the expression of large cohorts of RNA species to produce programmatic changes in cellular phenotypes. To describe the function of RBPs within a cell, it is key to identify their mRNA-binding partners. This is often done by crosslinking nucleic acids to RBPs, followed by chemical release of the nucleic acid fragments for analysis. However, this methodology is lengthy, which involves complex processing with attendant sample losses, thus large amounts of starting materials and prone to artifacts. To evaluate potential alternative technologies, we tested “exclusion-based” purification of immunoprecipitates (IFAST or SLIDE) and report here that these methods …

Live Cell Imaging Gas Control, Elsa M. Bean, Brady C. Berg, Abby A. Jens

Biomedical Engineering

The following document outlines the entire process for designing and manufacturing a Live Cell Imaging Gas Control subsystem in tandem with the Heated Stage subsystem to make a CO₂ and temperature-controlled chamber for use with the Olympus IX73P2F Microscope. It highlights the current literature and patents surrounding live cell imaging and touches on the existing live cell imaging setups currently being used by other entities. Following this, it defines the scope of the project, key customer requirements, and engineering specifications to ensure the design meets all the needs of its users. This document includes project planning steps to establish …

Verification Of A Digital Microfluidics Platform, Karanpartap Singh

Electrical Engineering

The electrowetting effect describes the change in contact angle between a solid surface and electrolyte in response to an applied electric potential difference. Given a planar array of individually-actuated electrodes, electrowetting can be used to transport, mix, and separate picoliter to microliter-sized droplets of liquid on a dielectric layer. Applications of this phenomenon range from lab-on-a-chip and other microfluidic devices to liquid lenses capable of altering their topology and focus within milliseconds.

This project extends prior work simulating the dependence of droplet velocity on actuation voltage and demonstrates observed physics on a physical platform. The simulation portion of this project …

Review: Biological Engineering For Nature-Based Climate Solutions, Benjamin R. K. Runkle

Biological and Agricultural Engineering Faculty Publications and Presentations

Nature-based Climate Solutions are landscape stewardship techniques to reduce greenhouse gas emissions and increase soil or biomass carbon sequestration. These mitigation approaches to climate change present an opportunity to supplement energy sector decarbonization and provide co-benefits in terms of ecosystem services and landscape productivity. The biological engineering profession must be involved in the research and implementation of these solutions—developing new tools to aid in decision-making, methods to optimize across different objectives, and new messaging frameworks to assist in prioritizing among different options. Furthermore, the biological engineering curriculum should be redesigned to reflect the needs of carbon-based landscape management. While doing …

Life Cycle Analysis Of Hydrogen Fuel Derived From Aluminum Versus Diesel, Tyson S. Metlen

Theses and Dissertations

The Department of Defense needs energy sources beyond petroleum products to effectively combat area denial strategies employed by its adversaries. Petroleum fuels are expensive, they have deleterious environmental impacts, and most of the world’s oil reservoirs are in volatile countries. A proposed alternative energy carrier is reacting aluminum with water to produce hydrogen and using the hydrogen as a fuel source. Normally aluminum forms a protective oxide layer that prevents continuous reaction but if aluminum is mixed with a 3.5% by weight gallium-indium eutectic, the oxide layer cannot form, and the reaction is sustainable. This study conducts a life cycle …

Evaluating Neural Network Decoder Performance For Quantum Error Correction Using Various Data Generation Models, Brett M. Martin

Theses and Dissertations

Neural networks have been shown in the past to perform quantum error correction (QEC) decoding with greater accuracy and efficiency than algorithmic decoders. Because the qubits in a quantum computer are volatile and only usable on the order of milliseconds before they decohere, a means of fast quantum error correction is necessary in order to correct data qubit errors within the time budget of a quantum algorithm. Algorithmic decoders are good at resolving errors on logical qubits with only a few data qubits, but are less efficient in systems containing more data qubits. With neural network decoders, practical quantum computation …

Minivette Integrated Sample Prep Funnel For Cepheid Cartridges, Hanna N. Blumer, Sophia Arias, Camille Porciuncula, Ben Runkle

Biomedical Engineering

This report covers the redesign of the Sample Prep Funnel for Cepheid’s engineering team. The Sample Prep Funnel, responsible for relaying liquid from the sample collection device to the testing cartridge, experiences fluid loss that causes invalid test results. Our group's task was to redesign this funnel to minimize fluid loss and, overall, increase efficiency and effectiveness.

Impacts Of Temperature And Carbon Dioxide On Boro Rice Production, Sabiha Ferdous

Department of Agricultural and Biological Systems Engineering: Dissertations, Theses, and Student Research

There are different anticipated impacts of climate change (CC) on agriculture all over the world. Bangladesh as a developing country has potential vulnerability and negative impacts on CC. This change in meteorological parameters creates negative impacts on agricultural production which is a threat to food security and economic development. The country has recently achieved food security in rice which is mainly due to increased yields and area coverage of irrigated dry season (Boro) rice over the last decades. It is necessary to predict the future Boro rice production in accordance with CC as well as take supplementary actions to ensure …

Biogeosciences Perspectives On Integrated, Coordinated, Open, Networked (Icon) Science, D. Dwivedi, A. L.D. Santos, M. A. Barnard, T. M. Crimmins, A. Malhotra, K. A. Rod, K. S. Aho, S. M. Bell, B. Bomfim, F. Q. Brearley, H. Cadillo-Quiroz, J. Chen, C. M. Gough, E. B. Graham, C. R. Hakkenberg, L. Haygood, G. Koren, E. A. Lilleskov, L. K. Meredith, S. Naeher, Z. L. Nickerson, O. Pourret, H. S. Song, M. Stahl, N. Taş, R. Vargas, S. Weintraub-Leff

Department of Agricultural and Biological Systems Engineering: Faculty Publications

This article is composed of three independent commentaries about the state of Integrated, Coordinated, Open, Networked (ICON) principles in the American Geophysical Union Biogeosciences section, and discussion on the opportunities and challenges of adopting them. Each commentary focuses on a different topic: (a) Global collaboration, technology transfer, and application (Section 2), (b) Community engagement, community science, education, and stakeholder involvement (Section 3), and (c) Field, experimental, remote sensing, and real-time data research and application (Section 4). We discuss needs and strategies for implementing ICON and outline short- and long-term goals. The inclusion of global data and international community engagement are …

Investigation Of Additively Manufactured Molybdenum-Tungsten-Rhenium Alloys, Randolph T. Abaya

Theses and Dissertations

The process of creating metal components through additive manufacturing is changing the way different industries can avoid the shortcomings of traditional metal production. Metals such as tungsten, molybdenum, and rhenium have many advantages for different applications, especially when alloyed together. In this study, an additively manufactured alloy containing 70% molybdenum, 25% tungsten, and 5% rhenium (70Mo-25W-5Re) is tested for its strength, ductility, hardness, and porosity. The 70Mo-25W-5Re alloy is printed through Laser Powder Bed Fusion (LPBF) under different conditions such as printing speed and printing atmosphere. Additionally, the effects of post printing heat treatment are conducted to understand the advantages …

The Use Of Electronic Nose In The Quality Evaluation And Adulteration Identification Of Beijing-You Chicken, Jingru Chen, Wenjie Yan, Yu Fu, Liang Wang, Xueze Lv, Ruitong Dai, Xingming Li, Fei Jia

Biological and Agricultural Engineering Faculty Publications and Presentations

The objective of this study was to reveal the secrets of the unique meat characteristics of Beijing-you chicken (BJY) and to compare the difference of quality and flavor with Luhua chicken (LH) and Arbor Acres broiler (AA) at their typical market ages. The results showed the meat of BJY was richer in essential amino acids, arachidonic acid contents, inosine monophosphate (IMP), and guanosine monophosphate (GMP). The total fatty acid and unsaturated fatty acid contents of BJY chicken and LH chicken were lower than that of AA broilers, whereas the ratios of unsaturated fatty acids/saturated fatty acids (2.31) and polyunsaturated fatty …

Multisector Dynamics: Advancing The Science Of Complex Adaptive Human-Earth Systems, Patrick M. Reed, Antonia Hadjimichael, Richard H. Moss, Christa Brelsford, Casey D. Burleyson, Stuart Cohen, Ana Dyreson, David F. Gold, Rohini S. Gupta, Klaus Keller, Megan Konar, Erwan Monier

Michigan Tech Publications, Part 1

The field of MultiSector Dynamics (MSD) explores the dynamics and co-evolutionary pathways of human and Earth systems with a focus on critical goods, services, and amenities delivered to people through interdependent sectors. This commentary lays out core definitions and concepts, identifies MSD science questions in the context of the current state of knowledge, and describes ongoing activities to expand capacities for open science, leverage revolutions in data and computing, and grow and diversify the MSD workforce. Central to our vision is the ambition of advancing the next generation of complex adaptive human-Earth systems science to better address interconnected risks, increase …

Influence Of Saccharide Modifications On Heparin Lyase Iii Substrate Specificities, Jiandong Wu, Pradeep Chopra, Geert Jan Boons, Joseph Zaia

Chemical and Biochemical Engineering Faculty Research & Creative Works

A Library of 23 Synthetic Heparan Sulfate (HS) Oligosaccharides, Varying in Chain Length, Types, and Positions of Modifications, Was Used to Analyze the Substrate Specificities of Heparin Lyase III Enzymes from Both Flavobacterium Heparinum and Bacteroides Eggerthii. the Influence of Specific Modifications, Including N-Substitution, 2-O Sulfation, 6-O Sulfation, and 3-O Sulfation on Lyase III Digestion Was Examined Systematically. It Was Demonstrated that Lyase III from Both Sources Can Completely Digest Oligosaccharides Lacking O-Sulfates. 2-O Sulfation Completely Blocked Cleavage at the Corresponding Site; 6-O and 3-O Sulfation on Glucosamine Residues Inhibited Enzyme Activity. We Also Observed that There Are Differences in …

Electro‐Driven Materials And Processes For Lithium Recovery—A Review, Anna Siekierka, Marek Bryjak, Amir Razmjou, Wojciech Kujawski, Aleksandar N. Nikoloski, Ludovic F. Dumée

Research outputs 2022 to 2026

The mass production of lithium‐ion batteries and lithium‐rich e‐products that are required for electric vehicles, energy storage devices, and cloud‐connected electronics is driving an unprecedented demand for lithium resources. Current lithium production technologies, in which extraction and purification are typically achieved by hydrometallurgical routes, possess strong environmental impact but are also energy‐intensive and require extensive operational capabilities. The emergence of selective membrane materials and associated electro‐processes offers an avenue to reduce these energy and cost penalties and create more sustainable lithium production approaches. In this review, lithium recovery technologies are discussed considering the origin of the lithium, which can be …