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Gravity Fed Hopper Flow Of Bulk Solids For Lunar Isru, Jason Bendixen Noe

Dissertations, Master's Theses and Master's Reports

With the return to the moon in the decade of the 2020s, there has been a renaissance of lunar technology development and innovation. This has been particularly true for the area of lunar ISRU (In-Situ Resource Utilization). One key area in ISRU that has been neglected is lunar regolith storage hopper research. Many lunar regolith ISRU researchers use storage hoppers in their work but do not document the properties when designing the hoppers or do not have the information at hand. Because of this, hopper design and documentation are poorly understood, and more research is needed. Hoppers are vital for …

The Integration Of Neuromorphic Computing In Autonomous Robotic Systems, Md Abu Bakr Siddique

Dissertations, Master's Theses and Master's Reports

Deep Neural Networks (DNNs) have come a long way in many cognitive tasks by training on large, labeled datasets. However, this method has problems in places with limited data and energy, like when planetary robots are used or when edge computing is used [1]. In contrast to this data-heavy approach, animals demonstrate an innate ability to learn by communicating with their environment and forming associative memories among events and entities, a process known as associative learning [2-4]. For instance, rats in a T-maze learn to associate different stimuli with outcomes through exploration without needing labeled data [5]. This learning paradigm …

Matrix Stiffness Sensing By Nascent Adhesions And The Role Of Riam In Adhesion Assembly, Nikhil Mittal

Dissertations, Master's Theses and Master's Reports

Mechanical stiffness of the extracellular matrix (ECM) impacts many cellular functions such as proliferation, migration, and differentiation. ECM stiffness is sensed by a cell via integrin-based focal adhesions (FAs) by changing conformation and biochemical activities of molecules within FAs by the exchange of the force between the ECM and filamentous actin (F-actin). Cells in turn respond to this stiffness by generating traction force that plays an important role in many biological events such as tissue morphogenesis, stem cell differentiation, wound healing, and cancer cell metastasis. The stiffness of the extracellular matrix induces differential tension within integrin-based adhesions. Understanding stiffness sensing …

Sustainable Use Of Wastewater In Concrete Construction, Mohammadamin Soltanianfard

Civil Engineering Dissertations - Archive

This dissertation investigates the use of wastewater from various treatment stages in concrete production to promote sustainable construction practices. Concrete prepared with potable water (PW) served as a control, while wastewater from plant final effluent (FE), chlorine contact basin (CL), secondary clarifier effluent (SC), primary clarifier effluent (PC), and bar screen effluent (BSE) was evaluated.

A comprehensive testing program was implemented to assess performance, including compressive strength tests, water absorption measurements, X-ray diffraction (XRD) analysis, thermogravimetric analysis (TGA), and scanning electron microscopy (SEM). Results showed that wastewater from advanced stages (FE, CL, SC) had minimal impact on strength and durability, …

Continuous, Platform Purification Of Viral Products Using Aqueous Two-Phase Extraction, Natalie M. Nold

Dissertations, Master's Theses and Master's Reports

Cell and gene therapies, a ground-breaking class of drugs that can heal genetic diseases and cure cancer, often have treatment costs over $1 million. Most cell and gene therapies are delivered using virus-based delivery vectors, which are incredibly expensive to manufacture. Liquid chromatography is the favored method of viral vector purification since it is easily scalable and can be functionalized to purify by biospecificity, charge, hydrophobicity, or size. However, chromatography-based purification processes are highly expensive and usually only recover 20-50% of the viral vectors. There is currently no platform purification strategy for viral vectors due to differences in their surface …

Optimizing Diabetes Diagnostics: Electrophoretic Separation And Detection Of Hemoglobin A1c With Boronate, Rixlie Fozilova

Dissertations, Master's Theses and Master's Reports

Diabetes affects 537 million people worldwide, while 136 million Americans have diabetes or prediabetes; roughly 22.6% of individuals are undiagnosed. Diabetes is the inability to regulate blood sugar levels. Hemoglobin A1c (HbA1c) is glycosylated hemoglobin and indicates average blood sugar levels over the past three months.

We adapted the selective boronic acid binding to the HbA1c sugar moieties from boronate affinity chromatography and translated it into a portable microchip paper-based electrophoresis platform. We explored a range of boronate concentrations at a steady voltage and sample volume to determine the optimal HbA1c binding and subsequent electrophoretic separation. A pH above 11 …

Multi-Functional Gelatin-Dithiolane Hydrogels For Tissue Engineering, Saad Asim

Dissertations, Master's Theses and Master's Reports

Biomaterials that integrate multiple functionalities, mimic the extracellular matrix (ECM) microenvironment to support cellular growth, and adhere robustly to damaged tissues are highly needed to advance tissue engineering. Protein-based biomaterials are promising due to their inherent biocompatibility, biomimicry, biodegradation, and cell-supportive properties. Herein, by leveraging the unique ability of dithiolanes to generate on-demand in-situ thiols, we developed a new class of dithiolane-modified, protein-based biomaterial that combines unique, seemingly opposing functions for tissue engineering. Dithiolane-modified gelatin, a model protein used herein, enabled photoinitiator-free photo-crosslinking to form multi-functional gelatin-dithiolane (GelDT) hydrogels, which displayed exceptional long-term stability in cell culture media (>28 …

Analytical And Machine Learning Modeling Of Direct Carbonation Of Natural Silicate Minerals, William Hanson

Dissertations, Master's Theses and Master's Reports

The climate-altering effects of atmospheric CO₂ make it necessary to develop innovative technologies that can remove it from the atmosphere. Mineral carbonation is a scalable technology to sequestrate and store CO2 in a stable carbonate mineral form. The efficiency of the mineral carbonation process depends on both feed mineralogy and process parameters. Comprehensive modeling and prediction of mineral carbonation efficiency for different CO₂ – reactive rocks has not been achieved in the past. In this thesis work, analytical and machine learning models are developed to predict the carbonation efficiency of dunite reactions. It is found that random forest …

Implementing Associative Learning Using Neuromorphic Robot, Vinay Kumar Pillalamarri

Dissertations, Master's Theses and Master's Reports

Associative learning, a key cognitive process seen across the animal kingdom, enables organisms to form connections between stimuli and adapt their behaviors based on past experiences. A particularly powerful example is fear conditioning, where animals learn to associate a neutral stimulus with an aversive one, allowing them to predict and avoid potential threats. Inspired by this mechanism, this project implements associative learning on an unmanned ground vehicle (UGV) to develop adaptive behavior through neuromorphic principles. Utilizing Nengo for neural modeling, the UGV learns to associate visual (red color) and tactile (vibration) stimuli through Hebbian learning, a biologically inspired synaptic adaptation …

Computational Analysis Of Vascular Aneurysms, Seyedmostafa Rezaeitaleshmahalleh

Dissertations, Master's Theses and Master's Reports

Vascular aneurysms, such as intracranial aneurysms (IAs) and abdominal aortic aneurysms (AAAs), pose significant health risks, particularly upon rupture. Disturbed hemodynamics, characterized by swirling flow patterns, can lead to cellular and structural changes that disrupt normal physiological processes and contribute to destructive vascular remodeling. Integrating hemodynamic analysis into clinical assessments of aneurysms has become crucial, especially through patient-specific computational fluid dynamics (CFD) simulations based on medical imaging. However, the complexity of CFD tools presents challenges in model creation and post-simulation analysis, limiting their accessibility to clinicians.
This project aimed to advance aneurysm management by exploring the role of intraluminal thrombus …

An Fpga-Based Eit System For Deep Space Medical Imaging, Kendall R. Farnham

Dartmouth College Ph.D Dissertations

Dangers associated with high radiation and microgravity exposure in space are critical challenges inhibiting us from exploring deep space and pursuing long-duration missions, as current medical systems are unable to monitor, diagnose, or treat tissue injury within physical spacecraft constraints and communication limits. Ultrasound (US) is the current imaging system used on the International Space Station, but this technology relies on telemedical support (or onboard artificial intelligence/autonomous capabilities) for both operation and diagnosis, posing challenges for crews isolated in deep space. Electrical impedance tomography (EIT) is a non-invasive, non-ionizing technology that produces images of the electrical properties of tissues and …

Pulse-Width Modulation Spray System Performance And Development Of A Novel System To Optimize Spray Use Efficacy, Prashanta Pokharel

Theses and Dissertations--Biosystems and Agricultural Engineering

The overarching objective of this research was to enhance our understanding of pulse width modulation (PWM) based nozzle control system and develop an intelligent nozzle control system for agricultural spray applications. This dissertation focused on measuring and analyzing the transient nozzle pressure characteristics and performance under PWM control. Additionally, it explored the development of an innovative multi-degree-of-freedom (DOF) nozzle control system for precise chemical applications in specialty crop systems.

The pressure dynamics of a PWM system were studied by developing an instrumentation system capable of operating a solenoid valve and recording pressure signals. A nozzle body and two manifolds of …

College Of Computing And Engineering Graduate Catalog 2024-2025, Nova Southeastern University

College of Psychological Services / College of Psychology Postgraduate Student and Course Catalogs

No abstract provided.

A Survey Of Strongyle Nematodes In New England Dairy Goats, D.J. Richardson, E.M. Wray, D. Watters, U. Hanif, E. Jalbert, E. Thompson, G. Trajkovic, A.R. Sirois, N. Pilotte

Journal of the Arkansas Academy of Science

The paucity of information concerning the occurrence of strongyle nematodes in New England dairy goats prompted a survey of 241 dairy goats from throughout New England. Of the 241 goats examined using the McMaster technique, 104 (42.7%) were infected with strongyles with a mean intensity (+ SE) of 369.7 + 45.8 eggs per gram. Subsequent molecular examination of 50 random samples from these goats revealed a prevalence of 88% infection specifically with Haemonchus contortus. Haemonchus contortus is the most important internal parasite of sheep and goats, exerting a crushing economic burden on the livestock industry worldwide due to lowered milk …

Electromechanical Mapping Of The In Vivo Porcine Heart And Stomach, Haley Nesmith Patton

All ETDs from UAB

Electrical excitation and mechanical function are integral to the physiologic activity of both the heart and stomach. Electrical depolarization through the myocardium triggers contraction in the heart. When normal sequences of electrical activity are disturbed, the heart’s mechanical function may also be disturbed, affecting its ability to pump blood effectively, sometimes fatally. Similarly, electrical waves called slow waves initiate gastric peristalsis. Abnormalities in slow wave propagation patterns can disturb the stomach’s ability to mechanically process gastric contents, sometimes resulting in delayed gastric emptying, nausea, and vomiting. The relationship between mechanical function and electrophysiology is not unidirectional, though. Mechanical stimuli can …

Characterization Of Antibody Repertoires Developed From Naive And Recall Responses, Nicholas C. Curtis

Dartmouth College Ph.D Dissertations

Adaptive immunity, comprised in part by the antibody repertoire, is the cornerstone of our ability to remain healthy amongst the plethora of pathogenic challenges we encounter daily. Despite the importance of understanding antibody repertoire development, much remains unknown about the composition and evolution of circulating antibodies in response to viral challenges. To better understand antibody repertoire development, we profiled the serum antibody repertoire using a combination of next-generation sequencing and serum antibody proteomics in the predominantly naïve response against SARS-CoV-2 spike and the recalled response to influenza hemagglutinin. The response to SARS-CoV-2 spike in four convalescent individuals was diverse (consisting …

An In-Vitro Model For Visualizing Intraocular Lens And Lens Capsule Interaction In Posterior Capsule Opacification, Amjad Chatila

Bioengineering Dissertations - Archive

Posterior Capsule Opacification (PCO) is a common complication post cataract surgery. It is believed that Intraocular Lens (IOL) physical and chemical properties would affect their PCO potential. The tight binding between IOL and posterior lens capsule (PLC) is believed to have a negative impact on PCO formation, as suggested in the “No space, no cell, no PCO” hypothesis. To test the hypothesis, we have recently developed an in vitro 3D system to simulate IOL and PLC physical interaction. To expand the function and capability of this system, one objective of my work was to develop the next generation adhesion force …

Novel Engineering Approaches For Orthopedic Injury Treatment And Infection Diagnosis, Cynthia Co

Bioengineering Dissertations - Archive

Bioengineering has made significant contributions to the treatment of orthopedic injury through interdisciplinary approaches. Central to these advancements are many orthopedic implants, including anchors and joint replacements, which have been designed to restore mobility. Despite their functional efficacy, these products have limited lifespan and are associated with many complications, such as implant-associated infection. The success of implant design and function, both in the short and long term, is paramount for enhancing patient outcomes and overall well-being. Therefore, my thesis work is dedicated to addressing these critical challenges, aiming to maximize their treatment effect while minimizing the implant-associated complications.

Long-term patient …

Development Of Synthetically Accessible Glycolated Polythiophenes For High-Performance Organic Electrochemical Transistors, Bowen Ding, Vianna N. Le, Hang Yu, Guanchen Wu, Adam V. Marsh, Edgar Gutiérrez-Fernández, Nicolás Ramos, Martina Rimmele, Jaime Martín, Jenny Nelson, Alexandra F. Paterson, Martin Heeney

Chemical and Materials Engineering Faculty Publications

Four glycolated polythiophene-based organic mixed ionic-electronic conductors (OMIECs), PE2gTT, PE2gT, PT2gTT, and PT2gT are prepared by atom-efficient direct arylation polymerization, avoiding the need for toxic organometallic pre- cursors. PE2gT, PT2gTT, and PT2gT are operable in p-type accumulation mode organic electrochemical transistors (OECTs), with PT2gT displaying the best device performance with a μC* product figure-of-merit of 290 F cm−1 V−1 s−1 . A record volumetric capacitance among p-type glycolated polythiophene OMIECs of 313 F cm−3 is observed for PE2gT, ascribed to the high proportion- ality of polar components in its materials design. The good OECT performance of PE2gT with μC* = …

The Integrated Behavioral Model Of Mental Health Help Seeking (Ibm-Hs): A Health Services Utilization Theory Of Planned Behavior For Accessing Care, Joseph H. Hammer, David L. Vogel, Patrick R. Grzanka, Nayeon Kim, Brian T. Keum, Claire Adams, Sarah A. Wilson

Chemical and Materials Engineering Faculty Publications

This article introduces the integrated behavioral model of mental health help seeking (IBM-HS), a theoretical model for understanding the constructs (e.g., systemic, predisposing, and enabling factors; mental health literacy; illness perceptions; perceived need; stigma; shame; perceived benefits, motivation) that influence people’s decision making around seeking professional mental health care and their ultimate access to formal treatment. The IBM-HS is a help-seeking-specific adaptation of the empirically supported integrated behavioral model and integrative model, which are themselves evolutions of the theory of planned behavior and theory of reasoned action. The IBM-HS posits that help-seeking determinants (e.g., structural forces; cultural influences; past help-seeking …

Underlying Substrate Effect On Electrochemical Activity For Hydrogen Evolution Reaction With Low-Platinum-Loaded Catalysts, Baleeswaraiah Muchharla, Peter V. Sushko, Kishor K. Sadasivuni, Wei Cao, Akash Tomar, Hani Elsayed-Ali, Adetayo Adedeji, Abdennaceur Karoui, Joshua M. Spurgeon, Bijandra Kumar

Electrical & Computer Engineering Faculty Publications

Platinum is known as the best catalyst for the hydrogen evolution reaction (HER) but the scarcity and high cost of Pt limit its widespread applicability. Herein, the role of the underlying substrate on the HER activity of dispersed Pt atoms is uncovered. A direct current magnetron sputtering technique is utilized to deposit transition metal (TM) thin films of W, Ti, and Ta as underlying substrates for extremely low loading of Pt (

Recent Progress In Microrna Detection Using Integrated Electric Fields And Optical Detection Methods, Logeeshan Velmanickam, Dharmakeerthi Nawarathna

Electrical & Computer Engineering Faculty Publications

Low-cost, highly-sensitivity, and minimally invasive tests for the detection and monitoring of life-threatening diseases and disorders can reduce the worldwide disease burden. Despite a number of interdisciplinary research efforts, there are still challenges remaining to be addressed, so clinically significant amounts of relevant biomarkers in body fluids can be detected with low assay cost, high sensitivity, and speed at point-of-care settings. Although the conventional proteomic technologies have shown promise, their ability to detect all levels of disease progression from early to advanced stages is limited to a limited number of diseases. One potential avenue for early diagnosis is microRNA (miRNA). …

Investigation Of The Effect Of Preparation Parameters On The Structural And Mechanical Properties Of Gelatin/Elastin/Sodium Hyaluronate Scaffolds Fabricated By The Combined Foaming And Freeze-Drying Techniques, Mansour Qamash, S. Misagh Imani, Meisam Omidi, Ciara Glancy, Lobat Tayebi

Electrical & Computer Engineering Faculty Publications

This paper aimed to evaluate the effects of different preparation parameters, including agitation speed, agitation time, and chilling temperature, on the structural and mechanical properties of a novel gelatin/elastin/sodium hyaluronate tissue engineering scaffold, recently developed by our research group. Fabricated using a combination of foaming and freeze-drying techniques, the scaffolds were assessed to understand how these parameters influence their morphology, internal microstructure, porosity, mechanical properties, and degradation behavior. The fabrication process used in this study involved preparing a homogeneous aqueous solution containing 8% gelatin, 2% elastin, and 0.5% sodium hyaluronate (w/v), which was then subjected to mechanical agitation at speeds …

A Review Of Emerging Sensor Technologies For Tank Inspection: A Focus On Lidar And Hyperspectral Imaging And Their Automation And Deployment, Sergio Pallas Enguita, Chung-Hao Chen, Samuel Kovacic

Electrical & Computer Engineering Faculty Publications

This paper reviews various sensor technologies for tank inspection, focusing on Light Detection and Ranging (LiDAR) and Hyperspectral Imaging (HSI) as advanced solutions for corrosion detection. These technologies are evaluated alongside traditional methods such as ultrasonic, electromagnetic, and thermographic inspections. This review highlights their potential to enhance inspection accuracy, reduce the limitations of manual inspection, and support integrated data analysis for comprehensive asset management. Additionally, this paper proposes a pathway for automating these techniques to streamline inspection processes and improve implementation in practical applications.

Methylene Blue-Mediated Photodynamic Therapy In Combination With Doxorubicin: A Novel Approach In The Treatment Of Ht-29 Colon Cancer Cells, Nima Rastegar-Pouyani, Jaber Zafari, Alireza Nasirpour, Hossein Vazini, Nabbaa Najjar, Seyedeh Zohreh Azarshin, Fatemeh Javani Jouni

Electrical & Computer Engineering Faculty Publications

Introduction: With an alarmingly growing number of patients diagnosed with colorectal cancer, adopting innovative anti-cancer approaches has recently garnered great attention. One interesting concept is the co-administration of cytotoxic agents and safer modalities such as photodynamic therapy (PDT), which can subsequently improve therapeutic efficacy and potentially reduce the risks of severe adverse effects and drug resistance. In the course of PDT, a locally injected photosensitizer (PS) is irradiated with a light source, which subsequently generates reactive oxygen species (ROS) and induces programmed cell death in tumor cells.

Methods: In this study, to evaluate the potential anti-cancer effects of chemotherapy combined …

An Overview Of The Relationships Between The Food Industry And Nanotechnology, Mehdi Koushki, Nasrin Amiri-Dashatan, Hossein Pourghadamyari, Hadi Khodabandehloo, Fatemeh Bagheri, Masoumeh Farahani, Lobat Tayebi

Electrical & Computer Engineering Faculty Publications

Background and Objective: Due to the growth of the global population, food demands are increasing. Hence, the need to develop more efficient methods for producing better quality, safer, and more sustainable food seems essential. In the past decades, the use of nanoscale materials has increased greatly due to the unique chemical, physical, and biological characteristics of nanomaterials compared to bulk materials. This research presents nanotechnology role in improving sensorial properties (taste, appearance, and texture) and safety aspects as well as processing and packaging of foods. The use of nano-omics-based technologies and artificial intelligence-nanotechnology-based technologies in the food industry is also …

Assessing Stormwater Management Pond Water Quality, Function, And The Potential Biotic Effects To Receiving Waters, Mitchell Elstone

Theses and Dissertations (Comprehensive)

The use of stormwater management ponds (SWMPs) has been increasing over the past five decades. However, an in-depth understanding of the daily performance of SWMPs and functionality during cold periods is limited. This is in part because mandated monitoring is relatively infrequent, and the assumption that SWMPs are inactive between storm events and during the winter. The goals of this research were to better understand daily stormwater (SW) characteristics, the performance of SWMPs based on current forms of evaluation and assess the potential for SWMP effluent to impact downstream biota. Influent and effluent samples from two SWMPs were collected daily …

Advancing Environmental Engineering: The Role Of Artificial Intelligence In Sustainable Solutions - A Short Review, Amirreza Talaie, Hesam Kamyab, Ashkan Razmfarsa

Management Faculty Publications

Artificial intelligence (AI) has emerged as a transformative force in environmental engineering, offering innovative solutions to complex environmental challenges. From air pollution monitoring and water resource management to waste management, climate change mitigation, and ecological preservation, AI is revolutionizing the way we address environmental issues. Machine learning, neural networks, and other AI technologies are enabling more accurate predictions, optimizing resource use, and improving conservation efforts. However, despite its many advantages, AI also faces challenges such as data availability, energy consumption, ethical concerns, and the need for transparency. This review explores the diverse applications of AI in environmental engineering, highlighting the …

Distal Urogenital Anatomy And Epithelial Morphology In The Male Cajun Chorus Frog, Pseudacris Fouquettei (Anura: Hylidae), S.E. Trauth

Journal of the Arkansas Academy of Science

I examined the microanatomy of the distal urogenital system in male Cajun Chorus Frogs (Pseudacris fouquettei) from a small sample (n = 6) collected in central Arkansas in March 2018 and February 2023. Specifically, my primary objectives were to investigate the following: (1) the paired Wolffian (urogenital) ducts caudally from the kidneys to their merging with the urodeum of the cloaca, (2) the structure of seminal vesicles (if present), and (3) the epithelial morphologies among the distal urogenital tract, the posterior alimentary canal, and cloaca. My histological analysis confirmed the presence of ampullae (sperm storage structures) as mid-duct expansions of …

Use Of Google Earth Streetview To Evaluate Nesting By The Cliff Swallow (Petrochelidon Pyrrhonota) In Lowlands Of Eastern Arkansas, With Reports Of New Records, R. Tumlison, Z. Autrey

Journal of the Arkansas Academy of Science

Cliff Swallows (Petrochelidon pyrrhonota) typically construct their mud nests under the overhangs of cliffs. However, construction of concrete bridges and overpasses has provided suitable nesting structure in the last few decades. As the number of such nesting sites have increased, the breeding range also has expanded. We evaluated the use of Google Earth Streetview as a means of cheaply harvesting data regarding nesting distribution. The gourd-shaped nests of Cliff Swallows were easily discernible via available imagery, and we were able to document previously unreported nest sites of this species in 6 counties in eastern Arkansas (5 from imagery, 1 from …