Digital Commons Network^™

Ultra-Sensitive Visible-Ir Range Fiber Based Plasmonic Sensor: A Finite-Element Analysis And Deep Learning Approach For Ri Prediction, Mohammad Al Mahfuz, Sumaiya Afroj, Afiquer Rahman, Md. Azad Hossain, Md. Anwar Hossain, Md Selim Habib

Electrical Engineering and Computer Science Faculty Publications

In this paper, a relatively simple and ultra-sensitive Photonic crystal fiber (PCF) based surface plasmon resonance (SPR) sensor is proposed for detecting different analyte refractive indices (RIs) ranging from 1.33 to 1.43 over a wide range of wavelength spectrum spanning 0.55 μm to 3.50 μm. The comprehensive finite-element simulations indicate that it is possible to achieve remarkable sensing performances such as wavelength sensitivity (WS) and figure of merit (FOM) as high as 123,000 nm/RIU and 683 RIU^-1, respectively, and extremely low value of wavelength resolution (WR) about 8.13×10⁻⁷ RIU. A novel artificial neural network (ANN) model is …

Production Of Biofertilizer From Fruit And Garden Waste, Neema Msuya

Tanzania Journal of Engineering and Technology (TJET)

The project focused on the production of bio-fertilizer from fruit and garden waste, with a specific emphasis on utilizing pineapple tops in the composting process. The objective was to produce and assess the properties of the bio fertilizer obtained from this process and evaluate its potential application in agriculture. In this study, the composting process was done in a 0.7 m long, 0.85 wide and 1.1 m high vessel, and 0.238 m3 pineapple top wastes, resulting in 0.35 m3 of biofertilizer. The bio fertilizer produced exhibited favorable characteristics, including a moisture content of 36%, pH of 7.1, and a total …

Assessment Of Risk Factors Related To Body Pain Complaints In Tanzania Construction Industry, Fatma K. Mohamed

Tanzania Journal of Engineering and Technology (TJET)

The construction industry is associated with risks that can result in musculoskeletal diseases. Although young male workers who are presumed to be healthy dominate the industry in Tanzania, body pain complaints have been widely reported. The aim of this study is to assess the prevalence and causes of body pains in workers. A cross-sectional study involving 396 workers was conducted. A chi square test was used for testing association of independent categorical variables and binary logistic regression analysis was used to determine predictors for body pain complaints. The results show that all study participants complained of at least one form …

An Optimization Tool For A Standalone Photovoltaic System, Johanes Kasilima

Tanzania Journal of Engineering and Technology (TJET)

Stand-alone photovoltaic systems (SAPV) are often used in remote areas where access to grid electricity is limited. This system depends on solar energy. However, Photovoltaic (PV) systems need a greater initial investment than conventional sources of energy, and their effectiveness is reliant on a number of environmental conditions such as the unpredictable solar radiation. One step in reducing the investment cost of a PV system is determining the optimal size of solar PV components that minimize costs. This paper presents a Particle Swarm based optimization tool for sizing Stand-alone PV systems. The optimization tool selects the optimal Levelized Cost of …

Kinetics-Based Inference Of Environment-Dependent Microbial Interactions And Their Dynamic Variation, Hyun-Seob Song, Na-Rae Lee, Aimee K. Kessell, Hugh C. Mccullough, Seo-Young Park, Kang Zhou, Dong-Yup Lee

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Microbial communities in nature are dynamically evolving as member species change their interactions subject to environmental variations. Accounting for such context-dependent dynamic variations in interspecies interactions is critical for predictive ecological modeling. In the absence of generalizable theoretical foundations, we lack a fundamental understanding of how microbial interactions are driven by environmental factors, significantly limiting our capability to predict and engineer community dynamics and function. To address this issue, we propose a novel theoretical framework that allows us to represent interspecies interactions as an explicit function of environmental variables (such as substrate concentrations) by combining growth kinetics and a generalized …

Electrochemical Syntheses Of Aryl-Substituted Benzothiophenes And Phenanthrenes Using Benzenediazonium Salts As The Aryl Radical Precursors, Li-Yuan Lan, Yang-Ye Jiang, Raymond Daniel Little, Cheng-Chu Zeng

Journal of Electrochemistry

Aryl-substituted benzothiophene and phenanthrene are important structural units in medicinal chemistry and materials science. Although extensive effort has been devoted to prepare these compounds and a variety of approaches have been developed to construct the 2-substituted benzothiophene core structure, environmental-friendly and efficient synthetic means are still desired. Based on our previous electrochemical Minisci-type arylation reaction with aryl diazonium salt as the aryl precursor, as well as the work from König’s group, herein, we described the use of paired electrolysis to achieve 2-aryl benzothiophenes and 9-aryl phenanthrenes employing benzenediazonium salts as the aryl radical precursors. Initially, 2-methylthiobenzendiazonium salt 1a and 4-methylbenzene …

Electrocatalytic Cyclopropanation Of Active Methylene Compounds, Liang-Hua Jie, Hai-Chao Xu

Journal of Electrochemistry

The development of novel strategies to access cyclopropanes has become increasingly important due to the vital role of these three-membered ring structures in synthetic intermediates, natural products, and pharmaceuticals. Herein, we present an electrocatalytic method for the synthesis of cyclopropanes through intermolecular dehydrogenative annulation of active methylene compounds and arylalkenes. This electrochemical process requires no chemical oxidants, allowing for a speedy access to various functionalized cyclopropanes from inexpensive and readily available materials.

Guidelines For Data Collection On Energy Performance Of Higher-Education Buildings In Egypt: A Case Study, Hesham Safwat, Ahmed A. Abdel-Rehim, Iman El-Mahallawi, Abdelwahab Hussein, Engy Elshazly, Ahmad Elshamy

Mechanical Engineering

Reliable energy analysis of buildings relies heavily on high-quality data leading to proper indicators. Previous studies have highlighted the importance of data quality in analyzing energy usage in residential and non-residential buildings in order to transform declarations to actions, optimise energy efficiency policies and monitor progress and failures in countries. Collected data must adhere to national and international standards for energy performance in buildings. This study aims to provide practical guidelines for effectively collecting and preparing data suitable for evaluating energy performance in Egyptian higher-education (HE) buildings. The guidelines are developed based on a comprehensive case study, considering data availability …

Spectrophotometric Device For Early Malaria Detection, Adrian Wasylewski, Christopher Faber, Victor Lin

Honors Thesis

Malaria remains a significant global health challenge, with millions of cases reported annually, particularly in resource-limited regions. Timely and accurate diagnosis is crucial for effective treatment and disease management. Unfortunately, there are still significant challenges in existing testing procedures, which are often expensive, inaccurate, or impractical for mass testing. While spectrophotometry has been proposed as a detection tool for other tropical diseases such as dengue fever, no prototype has been made for any disease, including malaria. This report addresses this gap by presenting a spectrophotometric-based malaria detection tool that achieves high sensitivity at a low cost. The inclusion of a …

A Synergistic Approach To Outreach And Teaching: Combining Service Learning At The College Level With A Summer Hands-On Outreach Program In Chemical And Biomolecular Engineering For High School Girls, Geeta Verma, Sogol Asaei, Jacob D. Hostert, Rebecca Ahn, Julie N. Renner

Faculty Scholarship

A synergetic approach to combine service learning at the university level with a high school outreach program is described. A holistic view is presented by discussing the importance of outreach and service learning, survey results, and outcomes. Overall, it was found that the unique program increased the self-efficacy (belief about one’s abilities) of students ranging from high school to graduate level, and positively impacted the social responsibility attitudes of university student participants.

Comparison Of Four In Vitro Test Methods To Assess Nucleus Pulposus Replacement Device Expulsion Risk, Tahmanna Rahman, Matthew J. Kibble, Gianluca Harbert, Nigel Smith, Erik Brewer, Thomas P. Schaer, Nicolas Newell

Rowan-Virtua School of Translational Biomedical Engineering & Sciences Departmental Research

Background

Nucleus replacement devices (NRDs) are not routinely used in clinic, predominantly due to the risk of device expulsion. Rigorous in vitro testing may enable failure mechanisms to be identified prior to clinical trials; however, current testing standards do not specify a particular expulsion test. Multiple methods have therefore been developed, complicating comparisons between NRD designs. Thus, this study assessed the effectiveness of four previously reported expulsion testing protocols; hula-hoop (Protocol 1), adapted hula-hoop (Protocol 2), eccentric cycling (Protocol 3), and ramp to failure (Protocol 4), applied to two NRDs, one preformed and one in situ curing.

Methods

Nucleus material …

Comparison Of Four In Vitro Test Methods To Assess Nucleus Pulposus Replacement Device Expulsion Risk, Tamanna Rahman, Matthew J. Kibble, Gianluca Harbert, Nigel Smith, Erik Brewer, Nicholas Newell

Rowan-Virtua School of Translational Biomedical Engineering & Sciences Departmental Research

Background: Nucleus replacement devices (NRDs) are not routinely used in clinic, predominantly due to the risk of device expulsion. Rigorous in vitro testing may enable failure mechanisms to be identified prior to clinical trials; however, current testing standards do not specify a particular expulsion test. Multiple methods have therefore been developed, complicating comparisons between NRD designs. Thus, this study assessed the effectiveness of four previously reported expulsion testing protocols; hula-hoop (Protocol 1), adapted hula-hoop (Protocol 2), eccentric cycling (Protocol 3), and ramp to failure (Protocol 4), applied to two NRDs, one preformed and one in situ curing. Methods: Nucleus material …

Applications, Challenges, And Research Issues For Enabling A Uav Swarm, Jennifer Hahner

Senior Honors Theses

Unmanned aerial vehicle (UAV) swarms have the potential to be useful in numerous applications due to their versatility and ability to operate without human intervention. However, this promising technology still requires further investigation, research, and testing before UAV swarms can be implemented extensively. The level of human intervention needed to control the system determines the differing levels of autonomy for UAV swarms. For swarms to become more independent, efficient algorithms for task and path planning are essential. In addition, accurate communication is essential for swarms to be able to coordinate and accomplish tasks successfully. This paper seeks to provide a …

Sparse Ensemble Networks For Hypserspectral Image Classification, Rakesh Kumar Iyer, Okan Ersoy

Department of Electrical and Computer Engineering Technical Reports

We explore the efficacy of sparsity and ensemble model in the classification of hyperspectral images, a pivotal task in remote sensing applications. While Convolutional Neural Networks (CNNs) and Transformer models have shown promise in this domain, each exhibits distinct limitations; CNNs excel in capturing the spatial/local features but falter to capture spectral features, whereas Transformers captures the spectral features at the expense of spatial features. Furthermore, the computational cost associated with training several independent CNN and Transformer networks becomes expensive. To address these limitations, we propose a novel ensemble framework comprising pruned CNNs and Transformers, optimizing both spatial and spectral …

Mathematical Modeling For Dental Decay Prevention In Children And Adolescents, Mahdiyeh Soltaninejad

Dissertations

The high prevalence of dental caries among children and adolescents, especially those from lower socio-economic backgrounds, is a significant nationwide health concern. Early prevention, such as dental sealants and fluoride varnish (FV), is essential, but access to this care remains limited and disparate. In this research, a national dataset is utilized to assess sealants' reach and effectiveness in preventing tooth decay, particularly focusing on 2nd molars that emerge during early adolescence, a current gap in the knowledge base. FV is recommended to be delivered during medical well-child visits to children who are not seeing a dentist. Challenges and facilitators in …

Microgravity Aeroponics System Project, Andrew W. Diddle

Morehead State Theses and Dissertations

A thesis presented to the faculty of the College of Science and Engineering at Morehead State University in partial fulfillment of the requirements for the degree Master of Science by Andrew W. Diddle on April 22, 2024.

Optimal Molecular Dynamics System Size For Increased Precision And Efficiency For Epoxy Materials, Khatereh Kashmari, Sagar Patil, Josh Kemppainen, Shankara Gowtham, Gregory Odegard

Michigan Tech Publications

Molecular dynamics (MD) simulation is an important tool for predicting thermo-mechanical properties of polymer resins at the nanometer length scale, which is particularly important for efficient computationally driven design of advanced composite materials and structures. Because of the statistical nature of modeling amorphous materials on the nanometer length scale, multiple MD models (replicates) are typically built and simulated for statistical sampling of predicted properties. Larger replicates generally provide higher precision in the predictions but result in higher simulation times. Unfortunately, there is insufficient information in the literature to establish guidelines between MD model size and the resulting precision in predicted …

Low Impedance, Durable, Self-Adhesive Hydrogel Epidermal Electrodes For Electrophysiology Recording, Naiyan Wu

McKelvey School of Engineering Graduate Student Theses & Dissertations

Traditional electrodes used for electrophysiology recording, characterized by their hard, dry, and inanimate nature, are fundamentally mismatched with the soft, moist, and bioactive characteristics of biological tissues, leading to suboptimal skin-electrode interfaces. Hydrogel materials, mirroring the high water content and biocompatibility of biological tissues, emerge as promising candidates for epidermal electronic materials due to their adjustable physicochemical properties. However, challenges such as inadequate electrical conductivity, elevated skin impedance, unreliable adhesion in moist conditions, and performance decline from dehydration have significantly restricted the efficacy and applicability of hydrogel-based electrodes. In this thesis, we report a high-performance hydrogel epidermal electrode patch for …

Development Of A Molten Salt Reactor Design And Design Framework For Overall Reactor Performance Prediction And Optimization, Andrew William Larsen

Theses and Dissertations

This dissertation introduces a novel approach to nuclear reactor design, emphasizing molten salt reactors (MSRs) to address the global need for safer, more efficient, and sustainable energy sources. It confronts the inherent challenges of nuclear fission reactors--proliferation risks, cost efficiency, waste management, and passive accident prevention--by developing an innovative MSR model and a machine learning (ML)-based optimization framework. The molten salt microreactor (MSMR), devised by researchers at Brigham Young University, utilizes thermally conductive plates for efficient heat dissipation during operational anomalies, ensuring safety within operational limits. This design was rigorously tested using STARCCM+ for fluid dynamics modeling and RELAP5-3D for …

Transferable User-Friendly Machine Learning For Normal Boiling Point Prediction, Frank Tafadzwa Mtetwa

Theses and Dissertations

The estimation of thermophysical properties of chemical compounds holds considerable importance across a multitude of fields, ranging from material science to process design. Among these properties, the normal boiling point (NBP) stands out as a pivotal parameter in scientific and engineering contexts, as it elucidates the state of a substance under standard conditions commonly encountered in nature. Additionally, NBP is extensively documented in various reference materials and databases. Given its paramount importance and widespread availability, prediction methodologies for other properties such as critical temperature, liquid density, vapor pressure, surface tension, liquid viscosity, liquid thermal conductivity, and flash point often rely …

Injectable And Rapidly Expandable Thrombin-Decorated Cryogels Achieve Rapid Hemostasis And High Survival Rates In A Swine Model Of Lethal Junctional Hemorrhage, Syed Muntazir Andrabi, S.M. Shatil Shahriar, Al-Murtadha Al-Gahmi, Benjamin L. Wilczewski, Mark A. Carlson, Jingwei Xie

Department of Mechanical and Materials Engineering: Faculty Publications

Effective therapies are urgently needed to stabilize patients with marginally compressible junctional hemorrhage long enough to get them to the hospital alive. Herein, we report injectable and rapidly expandable cryogels consisting of polyacrylamide and thrombin (AT cryogels) created by cryo-polymerization for the efficient management of lethal junctional hemorrhage in swine. The produced cryogels have small pore sizes and highly interconnected porous architecture with robust mechanical strength. The cryogels exhibit rapid shape memory properties and prove to be resilient against fatigue. These cryogels also show high water/blood absorption capacity, fast blood clotting effect, and enhanced adhesion of red blood cells and …

Faa Medical Reform, Dana Rose

Honors Projects

This project investigates the challenges and implications of obtaining medical certification for pilots with a history of childhood misdiagnoses, focusing on Attention-Deficit/Hyperactivity Disorder (ADHD). Misdiagnoses in childhood can lead to significant obstacles in the aviation industry's medical certification process, posing unique hurdles for aspiring pilots. The study examines the current FAA guidelines and procedures for medical certification, particularly the evaluation requirements for individuals with ADHD. It also explores common challenges faced by pilots, the effects of childhood misdiagnoses on their eligibility, and the impact of the FAA's ADHD evaluation process.

Through interviews with Aviation Medical Examiners (AMEs), this project identifies …

Anomaly Detection With Spiking Neural Networks (Snn), Shruti Bhandari, Vyshnavi Gogineni

ATU Scholars Symposium

Abstract:

Anomaly detection, the identification of rare or unusual patterns that deviate from normal behavior, is a fundamental task with wide-ranging applications across various domains. Traditional machine learning techniques often struggle to effectively capture the complex temporal dynamics present in real-world data streams. Spiking Neural Networks (SNNs), inspired by the spiking nature of biological neurons, offer a promising approach by inherently modeling temporal information through precise spike timing. In this study, we investigate the use of Spiking Neural Networks (SNNs) for detecting anomalies or unusual patterns in data. We propose an SNN model that can learn what constitutes normal …

Mechanical Characterization Of Hemp, Jute, And Flax Based Natural Fibre Composites For Non-Structural Applications In Aircraft And Automobiles, Ravi Kumar B

Theses and Dissertations

Demand for reducing energy consumption and detrimental environmental impacts after the effective lifetime of an engineering material are the major driving factors for the development of natural fibre reinforced composites (NFRCs) in various sectors. Compared to synthetic fibre like carbon-fibres or Kevlar, natural fibres provide several benefits including light weight, inexpensive, recyclability, superior specific strength, biodegradable, non-toxic during handling, and less energy intensive during manufacturing. This doctoral work presents observations from mechanical tests and interpretations on the suitability of natural fibre reinforced composites for less heavily loaded engineering applications areas.

In the first stage, jute, flax, and hemp fibres were …

Nanozyme-Based Sensing Of Dopamine Using Cobalt-Doped Hydroxyapatite Nanocomposite From Waste Bones, Umar Nishan, Nighat Jabeen, Amir Badshah, Nawshad Muhammad, Mohibullah Shah, Irfan Ullah, Saifullah Afridi, Jibran Iqbal, Muhammad Asad, Riaz Ullah, Essam A. Ali, Sarfraz Ahmed, Suvash Chandra Ojha

All Works

Dopamine is one of the most important neurotransmitters and plays a crucial role in various neurological, renal, and cardiovascular systems. However, the abnormal levels of dopamine mainly point to Parkinson’s, Alzheimer’s, cardiovascular diseases, etc. Hydroxyapatite (HAp), owing to its catalytic nature, nanoporous structure, easy synthesis, and biocompatibility, is a promising matrix material. These characteristics make HAp a material of choice for doping metals such as cobalt. The synthesized cobalt-doped hydroxyapatite (Co-HAp) was used as a colorimetric sensing platform for dopamine. The successful synthesis of the platform was confirmed by characterization with FTIR, SEM, EDX, XRD, TGA, etc. The platform demonstrated …

Acoustothermal Transfection For Cell Therapy, Xiufang Liu, Ning Rong, Zhenhua Tian, Joseph Rich, Lili Niu, Pengqi Li, Laixin Huang, Yandai Dong, Wei Zhou, Pengfei Zhang, Yizhao Chen, Congzhi Wang, Long Meng, Tony Jun Huang, Hairong Zheng

Faculty Publications

Transfected stem cells and T cells are promising in personalized cell therapy and immunotherapy against various diseases. However, existing transfection techniques face a fundamental trade-off between transfection efficiency and cell viability; achieving both simultaneously remains a substantial challenge. This study presents an acoustothermal transfection method that leverages acoustic and thermal effects on cells to enhance the permeability of both the cell membrane and nuclear envelope to achieve safe, efficient, and high-throughput transfection of primary T cells and stem cells. With this method, two types of plasmids were simultaneously delivered into the nuclei of mesenchymal stem cells (MSCs) with efficiencies of …

Ssnet: Exploiting Spatial Information For Tobacco Stem Impurity Detection With Hyperspectral Imaging, Chao Zhou, Zhenye Li, Dongyi Wang, Sheng Xue, Tingting Zhu, Chao Ni

Biological and Agricultural Engineering Faculty Publications and Presentations

Tobacco stems are a critical component in cigarette production in China. However, accurately and promptly identifying impurities in tobacco stems remains a challenge with current deep learning methods, often failing to meet industry standards. This study introduces the Spectral-Spatial Network (SSNet), which is specifically optimized for rapid and precise detection of impurities in tobacco stems, leveraging spatial information in hyperspectral imaging. Designed to align with the high-speed requirements of industrial processing, SSNet effectively overcomes the complexities associated with analyzing hyperspectral data. The integration of spatial information particularly enhances recognition accuracy, especially in areas affected by fringe patterns. Our experiments reveal …

Production Of Mrna Vaccine For Influenza, Christina Miller

Honors Theses

The objective of this project is to design a process to produce an mRNA influenza vaccine that serves as an alternative to conventional influenza vaccines, replacing current options with innovative mRNA technologies. Given that older populations are most likely to follow up on immunizations consistently, and the increasing average age worldwide, the market for this project appears to be expanding in the next 80 years. Additionally, experts predict more frequent mutations and outbreaks of viral disease from a variety of factors including globalization and global temperature trends. Rapid response to these viral outbreaks will continue to be as, or even …

Development Of Novel Analytical Methods For The Investigation Of Mammalian Tissues And Cells, Grace A. Binder

USF Tampa Graduate Theses and Dissertations

This dissertation endeavors to advance the frontiers of analytical chemistry by addressing critical challenges across three distinct chapters. In the first chapter, the focus is on the evaluation of digestion methods for the analysis of trace metals in mammalian tissues and the Standard Reference Material NIST 1577c. The primary goal is to optimize methodologies, laying the groundwork for reliable trace metal analysis and furthering our understanding of their roles in biological systems.

Transitioning into the realm of immunomodulation, the second chapter elucidates immune response, disease and treatment through the optimization and discovery of STING modulators, utilizing the luciferase assay for …

Development Of Zr(Iv) Mof-Enabled Nerve Agent Electrochemical Hydrolysis Sensors, Tyler James Marlar

Theses and Dissertations

Nerve agents are acetylcholinesterase inhibitors and among the most toxic chemical warfare agents ever synthesized. Detection of these chemicals is critical for the protection of populations and strategic resources. G-series nerve agents are volatile compounds. V-series nerve agents are persistent phosphonothioate compounds. Persistent nerve agents do not readily volatilize and can contaminate environmental resources for extended periods. While nerve agents are inherently non-electroactive, they can be hydrolyzed to electroactive products compatible with electrochemical sensing. Zr(IV) MOFs are next-generation nanoporous materials, which have been shown to rapidly catalyze nerve agent hydrolysis. In this work, the catalytic processes of MOF-808, a specific …