Digital Commons Network^™

Expression Of A Heterologous Protein C In Mammary Tissue Of Transgenic Animals Using A Long Whey Acidic Protein Promoter , William H. Velander, Henryk Lubton, William N. Drohan, Lothar Hennighausen

Papers in Biotechnology

An isolated DNA sequence which regulates the expression of a heterologous gene composed of a mouse whey acidic protein promoter having a length of greater than about 2.4 kb extending upstream from the unique KpnI site in the mouse whey acidic protein gene is disclosed. Specifically a mouse whey acidic protein promoter of about 4.1-4.2 kb in length extending upstream from the unique KpnI site is preferred. This mouse whey acid protein promoter is operably linked to a DNA sequence encoding a heterologous polypeptide and used to prepare transgenic non-human mammals expressing the heterologous polypeptide in their milk. Particularly efficient …

Role Of Nitric Oxide As A Modulator Of Platelet Dense Granule Release, Clifton Ford Frilot Ii

Doctoral Dissertations

Nitric oxide (NO) has been shown to suppress platelet activation, induce vasodilation, inhibit smooth muscle cell proliferation, and act against infection. Activated platelets generally have opposite effects from these. They secrete platelet-derived growth factor (PDGF), which stimulates smooth muscle growth, serotonin, which is a platelet agonist, and a number of agents that promote further platelet aggregation. However, activated platelets also produce NO through the enzymatic functions of the constitutive form of nitric oxide synthase (NOS). The primary functions of this capability are not yet completely understood. Due to its low molecular weight and high diffusivity, NO is quickly transported from …

Santa Clara Magazine, Volume 43 Number 1, Summer 2001, Santa Clara University

Santa Clara Magazine

2 - 150TH ANNIVERSARY MEMORIES In honor of SCU's sesquicentennial year, alumni reflect on their Bronco experiences.

4 - "SHEN FU" LEARNED THE GRACE OF ANGER By Tennant Wright, S.J. A friend shares his memories of Philip Oliger, S.J., who taught him that "passion is the sign that we are alive."

14 - WINGING IT By Adam Breen. Professor Bill Stover is a volunteer pilot for The Flying Doctors, a humanitarian group that brings free basic health and dental care to underprivileged communities in Mexico.

18 - SAVING GRACE By Elizabeth Kelly Gillogly '93. Santa Clara University's 150 years come …

Impulse, Dave Graves, Kyle Johnson, Mariah Johnson

Impulse (Jerome J. Lohr College of Engineering Publication)

Features:
[Page] 2 S is for success: New effort introduces Native American teens to college. [Page] 4 The New Leader: SDSU educator brings varied experience to the dean's office.
[Page] 6 Crescendo at Crothers Engineering hall being renovated, expanded in $7 million effort.
[Page] 8 Engineering landmark Solberg Hall gets special treatment with renovation.
Students:
[Page] 20 Golden tribute to the silver-haired dean
[Page] 21 Remund doubles up with teaching honors
[Page] 21 "Detail guy' honored for work
[Page] 22 Making models in a hurry
[Page] 23 Persistence pays off for Selim with increased LTAP funding
[Page] 25 Triaxial …

Evaluation Of Residual Chlorothalonil Levels On Processing Tomato Foliage Using The Tom-Cast Spray Program, Jane M. Patterson, Sue E. Nokes, Mark A. Bennett, Richard E. Riedel

Biosystems and Agricultural Engineering Faculty Publications

Field tomatoes were sprayed with chlorothalonil on a fixed–interval spray program and a TOM–CAST spray program with disease severity value threshold of 18. Foliage samples from upper and lower canopy layers were collected prior to spray re–applications. Chlorothalonil residue data were compared to the chlorothalonil efficacy threshold (1.2 μg/cm²). Using a seven–day interval program, eight of the nine and seven of the nine spray intervals had chlorothalonil residues above the critical level for the upper and lower canopy layers, respectively. Using the TOM–CAST program, four of the five spray intervals had chlorothalonil residues above the critical level for …

Influence Of Inoculum Size On Phytase Production And Growth In Solid-State Fermentation By Aspergillus Niger, Chundakkadu Krishna, Sue E. Nokes

Biosystems and Agricultural Engineering Faculty Publications

Solid–state fermentation is experiencing renewed interest for industrial enzyme production. Previous studies on the effects of fungal inoculum size on product yield have focused on spore inoculum. However, some organisms require vegetative inocula. This study investigated the effects of initial inoculum colony age, vegetative inoculum size, and duration of fermentation on the production of fungal biomass and phytase in solid–state fermentation using Aspergillus niger grown on wheat bran and soy meal. Initial inocula from 7– and 14–day–old potato dextrose agar (PDA) plates were used to study the effect of inoculum colony age in liquid culture and its further influence on …

Benzene Toxicity And Removal In Laboratory Phytoremediation Studies, Joel Gerard Burken, Carla Ross, Lisa M. Harrison, Adrian Marsh, Lars Zetterstrom, Juel S. Gibbons

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

Hybrid Poplar Cuttings Were Shown to Impact the Fate and Transport of Subsurface Benzene, While Toxicity to the Poplars Was Not Observed. Laboratory Experiments Investigated the Toxicity Response of Poplar Cuttings to Benzene Exposure, Contaminant Distribution in Plant Tissues, Contaminant Degradation in the Soil Profile, and Contaminant Volatilization from the Soil and Plant Tissues. Two Separate Studies Were Conducted to Evaluate These Parameters. the First Study Examined the Toxicity of Benzene to Hybrid Poplar Cuttings in Batch Reactors. Poplar Cuttings Were Exposed to Various Concentrations of Benzene Contaminated Water in Two Different Types of Soil. Transpiration Rates Were Measured as …

Public Involvement In Highway Improvement: A Comparison Of Three Different Visualization Modes For A Case Study In Central Kentucky, Joel Brumm, Keiron Bailey, Ted H. Grossardt

Kentucky Transportation Center Faculty and Researcher Publications

Public involvement in highway improvement presents a set of complex problems involving many stakeholders.Since visualizations are increasingly regarded as essential tools in this process, a clearer understanding of the specific merits of advanced visualization techniques and their potential contributions must be developed.As a step towards integrating visualizations into an improved public planning paradigm termed Structured Public Involvement (SPI), this paper investigates the utility and performance of three visualization modes, termed 2D, 3D and VR (Virtual Reality), for a case study highway in Central Kentucky.

Visualization scenarios were designed and engineered according to the principle of elemental decomposition.Using a combination …

Abnormal Cell Detection Using The Choquet Integral, R. Joe Stanley, James M. Keller, Charles William Caldwell, Paul D. Gader

Electrical and Computer Engineering Faculty Research & Creative Works

Automated Giemsa-banded chromosome image research has been largely restricted to classification schemes associated with isolated chromosomes within metaphase spreads. In normal human metaphase spreads, there are 46 chromosomes occurring in homologous pairs for the autosomal classes 1-22 and the X chromosome for females. Many genetic abnormalities are directly linked to structural and/or numerical aberrations of chromosomes within metaphase spreads. Cells with the Philadelphia chromosome contain an abnormal chromosome for class 9 and for class 22, leaving a single normal chromosome for each class. A data-driven homologue matching technique is applied to recognizing normal chromosomes from classes 9 and 22. Homologue …

The Effect Of Multiple Pulses On Bacteria, Ramy El-Sayed Aly

Electrical & Computer Engineering Theses & Dissertations

Pulsed electric fields are widely used for bacterial decontamination of water and liquid food [I]. Depending on pulse amplitude and duration, a certain percentage of the bacteria suffer irreversible damage and, consequently, cell death. We have explored the effect of microsecond pulses of 13 kV/cm and 15 kV/cm electric field amplitude on the viability of Escherlchia coli. The pulse duration was varied from 4 μs to 32 μs, and the pulse number of 4 μs pulses from one to eight, Finally, the effect of separation between pulses was studied. The pulses were generated by means of a generator where …

Use Of Short-Pulse Laser For Optical Tomography Of Tissues, Kunal Mitra, Tuan Vo-Dinh

Biomedical Engineering and Sciences Faculty Publications

This paper analyzes the short pulse laser propagation through tissues for development of a time-resolved optical tomography system for detection of tumors and inhomogeneities in tissues. Traditional method for analyzing optical transport in tissues is the parabolic or diffusion approximation in which the energy flux is assumed proportional to the fluence (intensity averaged over all solid angles) gradients. The inherent drawback in this model is that it predicts infinite speed of propagation of the optical signal. In this paper accurate hyperbolic or wave nature of transient radiative transfer formulation is used to overcome such drawbacks. The transmitted and reflected intensity …

Wright State University College Of Engineering And Computer Science Bits And Pcs Newsletter, Volume 17, Number 9, June 2001, College Of Engineering And Computer Science, Wright State University

BITs and PCs Newsletter

An eight page newsletter created by the Wright State University College of Engineering and Computer Science that addresses the current affairs of the college.

Characterizing And Calibrating A Large Helmholtz Coil At Low Ac Magnetic Field Levels With Peak Magnitudes Below The Earth's Magnetic Field, Robert A. Schill, Karin V. Hoff

Electrical & Computer Engineering Faculty Research

Characterizing and calibrating a low impedance large Helmholtz coil generating 60 Hz magnetic fields with amplitudes well below the earth’s magnetic field is difficult and imprecise when coil shielding is not available and noise is an issue. Parameters influencing the calibration process such as temperature and coil impedance need to be figured in the calibration process. A simple and reliable calibration technique is developed and used to measure low amplitude fields over a spatial grid using a standard Hall effect probe gaussmeter. These low amplitude fields are typically hard or impossible to detect in the presence of background fields when …

Parametric Study Of Heavy Metal Partitioning In A Pilot Scale Incinerator Burning Simulated Municipal Solid Waste, Sukrut S. Thipse

Dissertations

Incineration is a combustion process used to convert toxic waste to benign gases and residue in presence of excess air. The products of the incineration process are bottom ash, fly ash and the flue gas. Most of the metal-based phases formed in incineration are toxic and their emissions need to be strictly controlled. Therefore, behavior of metal species during incineration must be well understood. Such understanding is possible based on the experimental identification of the metal phases formed in the waste combustion and determination of their concentration in various incineration products.

A pilot-scale incinerator of 140,000 Btu/hr capacity was constructed, …

Predicting Thermodynamic And Transport Parameters For Metal Contaminant Sorption To Hydrated Metal Oxides In Aquatic Systems, Paras Trivedi

Dissertations

Hydrated oxides such as HAO,'HFO, goethite, and BA40 are prevalent in soils and sediments as discrete particles or as coatings. These microporous oxides have large surface areas and high affmity for metal ions, and hence they act as both a sink and a source for anthropogenically released metal contaminants. To better understand risks posed by metals in the environment and to develop effective waste management programs, mechanistic models are needed to accurately predict their fate in soils and sediments.

To achieve this objective, sorption of metal ions Sr, Cd, Zn, Ni, and Ca to these oxides were studied with macroscopic …

Partial Characterization Of Extruded Collagen Tubes With Varied Material Deposition And Orientation Based On Rotation Rate And Linear Draw Speed, Richard Peter Hoppe

Theses

This study established protocols for extrusion of collagen tubes from an extruder made by the ZOKO Corporation of Czechoslovakia. Using a viscous collagen base material, collagen tubes can be formed with changes in rotation rates from 0 rpm to 260 rpm and linear draw speeds from 383 mm/min to 1270 mm/min with a constant extrusion rate of 50 cm²/min. These tubes, with further research and treatment, can be used for various medical applications including vascular implants and nerve conduits.

Post-extrusion, chemical crosslinking of the collagen increased the cohesiveness and mechanical integrity of the tubes. Microscopic photographs confirmed higher …

Studies On The Formation Of Dna-Cationic Lipid Composite Films And Dna Hybridization In The Composites, Murali Sastry, Vidya Ramakrishnan, Mrunalini Pattarkine, Krishna N. Ganesh

Faculty Works

The formation of composite films of double-stranded DNA and cationic lipid molecules (octadecylamine, ODA) and the hybridization of complementary single-stranded DNA molecules in such composite films are demonstrated. The immobilization of DNA is accomplished by simple immersion of a thermally evaporated ODA film in the DNA solution at close to physiological pH. The entrapment of the DNA molecules in the cationic lipid film is dominated by attractive electrostatic interaction between the negatively charged phosphate backbone of the DNA molecules and the protonated amine molecules in the thermally evaporated film and has been quantified using quartz crystal microgravimetry (QCM). Fluorescence studies …

Difi: Digital And Fiber, Wendy Angel

SWITCH

This article discusses the similarities between the histories of digital technologies and textiles. The author describes the ways that digital and fiber technologies are affected by the growing arts and cultures. The author provides details of how digital and fiber technologies are both used as signal-transmitting information media. The article describes the importance of both digital and fiber in societal standing, the power and status it generates, and how they separates the wealthy and the working class. The article closes with an interpretative analysis of the interwoven properties between industry, information, technology, and art.

Wright State University College Of Engineering And Computer Science Bits And Pcs Newsletter, Volume 17, Number 7, April 2001, College Of Engineering And Computer Science, Wright State University

BITs and PCs Newsletter

An eight page newsletter created by the Wright State University College of Engineering and Computer Science that addresses the current affairs of the college.

Ground Movement Associated With Microtunneling, Zhenyang Duan

Doctoral Dissertations

Microtunneling is a trenchless technology for construction of pipelines. Its process is a cyclic pipe jacking operation. Microtunneling has been typically used for gravity sewer systems in urban areas. Despite its good success record overall, several large ground settlement cases caused by microtunneling have been reported. Also, in contrast with large diameter urban tunneling, there are few research projects about the ground settlement caused by microtunneling.

In this dissertation, the ground settlement caused by microtunneling is studied using a theoretical approach, empirical approach, numerical simulation approach, and artificial intelligence approach.

In the theoretical approach, the equivalent ground loss and settlement …

Santa Clara Magazine, Volume 42 Number 4, Spring 2001, Santa Clara University

Santa Clara Magazine

3 - EL SOL SHINED IN 1968 STUDENT ELECTIONS By Adam Breen. During the 1968 campus elections, an electrical engineering student felt the student body was too apathetic, so he ran for dictator to spur interest. He could have been king, but instead had himself "assassinated " for a greater cause.

12 - DOUBLE LIVES By Susan Vogel. An economic boom in Silicon Valley created opportunities, jobs, and wealth-but those who work here often can't afford to live here. What are employees and employers doing about it?

16 - THE GLACIER PRIEST By Jeff Kunkel. Bernard Hubbard, S.J., was more …

The Role Of Eeg Biofeedback Training Preceding An Automated Monitoring Task, Matthew Bernd Hilscher

Master's Theses - Daytona Beach

Discussions are taking place in aviation circles to revamp and revolutionize air traffic management under the term "free-flight". The plans for a new system would incorporate, to a high degree, automation technologies that may have important human factors implications. One such concern speaks to quality of mental involvement as authority roles change. This modification of cerebral involvement may have an effect on performance during critical system failures. The purpose of this research has been to investigate whether specialized EEG biofeedback training might have an ameliorating effect on reducing the vigilance decrement. Partial support was found that evidences utility to this …

Nebraska Blueprint - Spring 2001

Nebraska Blueprint (Student Publication)

Table of Contents:

From the Editor
Students uncover the secrets of the Magic Kingdom
Student Life on the Sixth Floor
Celebrating National Engineers Week at PKI
NSBE lights its torch at UNL
Undergraduates benefit from conducting research
Postcard from Paris
Out of the starting blocks

Maximum Acceptable Oral Reading Speed For Voice Input Systems, Nirari M. Oda

Masters Theses

The objective of this thesis was to study the effect of vocal duration period and background noise on psychophysical oral reading speed. Ten healthy white males (21-28 years old) were used as subjects. Experiment one was designed to determine Maximum Acceptable Oral Reading Speed (MAORS) for an 8-hour period using psychophysical methodology. Results indicate that 114 words/min was an acceptable oral reading rate for an 8-hour day. Furthermore, 2 hours and 20 minutes is an acceptable testing period ( equivalent to the 8-hour day). Acoustical and physiological variables support these findings. Experiment two was designed to study the effect of …

Statistical Properties Of Maximum Likelihood Estimates For Accelerated Lifetime Data Under The Weibull Model, Mahmoud A. Yousef

Doctoral Dissertations

Pipe rehabilitation liners are often installed in host pipes that lie below the water table. As such, they are subjected to external hydrostatic pressure. The external pressure leads to early deformation in the liners, which could ultimately lead to its failing or buckling before its expected service lifetime is achieved. Experiments involving long term buckling behavior of liners are typically accelerated lifetime testing procedures. In an accelerated testing procedure a liner is subjected to a constant external hydrostatic pressure and observed until it fails or for a certain time, t whichever occurs first. Liners that do not fail at time …

Simultaneous Capture And Mineralization Of Coal Combustion Flue Gas Carbon Dioxide (Co2), Morris D. Argyle, Katta J. Reddy, Sanil John, Hollis Weber, Pradip Bhattacharyya, David T. Taylor, Mikol Christensen, Thomas Foulke, Paul Fahlsing

Faculty Publications

The mineral carbonation, a process of converting CO2 into stable minerals (mineralization), has been studied extensively to capture and store CO2. However, most of the mineral carbonation studies have been largely investigated at lab scale. Preliminary and pilot scale studies for accelerated mineral carbonation (AMC) were conducted at one of the largest coal-fired power plants (2120 MW) in the USA by reacting flue gas with fly ash particles in a fluidized bed reactor. In the preliminary experiments, flue gas CO2 and SO2 concentrations decreased from 13.0 to 9.6% and from 107.8 to 15.1 ppmv, respectively during the first 2 min. …

2001 - The Sixth Annual Symposium Of Student Scholars

Symposium of Student Scholars Program Books

The full program book from the Sixth Annual Symposium of Student Scholars, held on March 30, 2001. Includes abstracts from the presentations and posters.

Seismic Design Of Mixed And Hazardous Waste Landfills, Edward Kavazanjian Jr., Neven Matasovic

International Conferences on Recent Advances in Geotechnical Earthquake Engineering and Soil Dynamics

Due to the absence of federal criteria, seismic design and performance criteria for mixed and hazardous waste landfills are generally developed on a project-specific basis, supplemented by state and project-specific standards. In developing project-specific criteria, the federal Subtitle D standards for seismic design of municipal solid waste landfills are often used as a minimum standard for mixed and hazardous waste facilities. Seismic performance standards are also usually developed on a project-specific basis, employing either a “withstand without harmful discharge” or a “withstand without damage” performance standard, depending on the certainty of continuing aftercare. Quantitative criteria established to demonstrate compliance with …

Wright State University College Of Engineering And Computer Science Bits And Pcs Newsletter, Volume 17, Number 6, March 2001, College Of Engineering And Computer Science, Wright State University

BITs and PCs Newsletter

An eight page newsletter created by the Wright State University College of Engineering and Computer Science that addresses the current affairs of the college.

A Mechanistic Model For Internal Bone Remodeling Exhibits Different Dynamic Responses In Disuse And Overload, Scott J. Hazelwood, R. Bruce Martin, Mark M. Rashid, Juan J. Rodrigo

Biomedical Engineering

Bone is a dynamic tissue which, through the process of bone remodeling in the mature skeleton, renews itself during normal function and adapts to mechanical loads. It is, therefore, important to understand the effect of remodeling on the mechanical function of bone, as well as the effect of the inherent time lag in the remodeling process. In this study, we develop a constitutive model for bone remodeling which includes a number of relevant mechanical and biological processes and use this model to address differences in the remodeling behavior as a volume element of bone is placed in disuse or overload. …