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Analysis Of Site-Specific Adjustment Applied To On-The-Go Soil Sensing Data For Agronomic Use, Allison K. Jonjak

Department of Agricultural and Biological Systems Engineering: Dissertations, Theses, and Student Research

Successful variable-rate applications of agricultural inputs such as lime rely on the quality of input data. Systematic grid soil sampling is the most common method used for creating variable rate prescription maps. The insufficient number of point measurements usually obtained using this method has been primarily responsible for the typical inaccuracies seen in lime prescription maps. To increase sampling density, on-the-go sensing technology was developed for the mapping of soil pH and other relevant attributes. In this study, five fields in eastern Nebraska were mapped using both on-thego sensing technology and systematic grid sampling. Ten calibration points per field were …

Continuous, Passive Liquid-Liquid Extraction And Emulsion Separation Within Microfluidic And Millifluidic Devices, Janet Tesfai

Master’s Theses

Liquid-liquid extraction (LLE) is a method used to separate compounds based on their relative activity in two immiscible phases. By significantly reducing the scale of liquid-liquid extraction to the micro- and milli-fluidic levels, this separation process can bemade suitable for low volume, high value materials.

Multi-Scale Modeling Of The Fontan Circulation Using A Mock Circulatory System, John Chiulli

All Theses

The Fontan circulation is the result of a series of operations performed to save the lives of children born with univentricular circulations. The Fontan procedure achieves venous return to the pulmonary circulation without a ventricular power source. The load on the heart is reduced to normal, and these patients can lead a normal life into adulthood, although late complications continue to prevent normal lifespan. A unique feature of the Fontan circulation is the dependency of inferior vena cava flow on respiration. The Fontan circulation has been modeled experimentally using an adjustable mock circulatory system, which for the first time includes …

Application Of Gis And Geographically Weighted Regression To Evaluate The Spatial Non‐Stationarity Relationships Between Precipitation Vs. Irrigated And Rainfed Maize And Soybean Yields, Vivek Sharma, Ayse Kilic, Isa Kabenge, Suat Irmak

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Understanding the relationship between the spatial distribution of precipitation and crop yields on large scales (i.e., county, state, regional) while accounting for the spatial non‐stationarity can help managers to better evaluate the long‐term trends in agricultural productivity to make better assessments in food security, policy decisions, resource assessments, land and water resources enhancement, and management decisions. A relatively new technique, geographically weighted regression (GWR), has the ability to account for spatial non‐stationarity with space. While its application is growing in other scientific disciplines (i.e., social sciences), the application of this new technique in agricultural settings has not been practiced. The …

Narrow Grass Hedge Control Of Nutrient Loads Following Variable Manure Applications, John E. Gilley, Lisa M. Durso, Roger Eigenberg, David B. Marx, Brian L. Woodbury

Department of Agricultural and Biological Systems Engineering: Faculty Publications

The effectiveness of a narrow grass hedge in reducing runoff nutrient loads following manure application was examined in this study. Beef cattle manure was applied to 0.75 m wide by 4.0 m long plots established on an Aksarben silty clay loam located in southeast Nebraska. Manure was added at rates required to meet none or the 1, 2, or 4 year nitrogen requirements for corn. Runoff water quality was measured during three 30 min simulated rainfall events. Manure application rate significantly affected dissolved phosphorus (DP) and total phosphorus (TP) loads in runoff on the plots without a grass hedge. However, …

Characterization Of Potential Health Promoting Lipids In The Co-Products Of De-Flossed Milkweed, Vicki Schlegel, Richard Zbasnik, Tammy Gries, Bo Hyun Lee, Timothy Carr, Ji-Young Lee, Curtis Weller, Susan Cuppett

Department of Agricultural and Biological Systems Engineering: Faculty Publications

The floss and oil of the common milkweed (Asclepias syriaca L.) seeds are currently used to produce comforters/pillows and skin care products, respectively. As an outcome of these products, copious quantities co-products (pressed seed meal and pod biomass) are disposed of each year despite the presence of potential health benefiting lipids. The objective of this project was to determine the feasibility of developing the lipid fraction from of these co-products for the fast growing dietary human health market. Although certain types of lipids were affected by the extraction solvent used (hexane and diethyl ether) as were overall amounts, analysis …

Evaluation Of Manganese Control In The Source Water And Microfiltration Plant Of A South Carolina Water Utility, Daniel Lewis

All Theses

Although present in most water supplies, manganese is a difficult-to-treat nuisance contaminant in drinking water. The US Environmental Protection Agency (EPA) has set a Secondary Maximum Contaminant Level (SMCL) of 0.05 mg/L but experts have recommended a goal of 0.02 mg/L or less to avoid chronic issues with the metal. This work is a report on manganese control for the Startex-Jackson-Wellford-Duncan (SJWD) Water District, a water utility in northwestern SC. Fourteen locations were sampled from June 2010 through October 2011. Manganese, iron, dissolved organic carbon, dissolved oxygen, and other relevant parameters were measured.
The lake-fed Middle Tyger River is the …

Clean Energy Water Disinfection International Environmental Education Design Contest, Howard Heffington

Chemical Engineering Undergraduate Honors Theses

Many technologies are used for water disinfection. Chlorine, iodine, and ozone are some chemical methods of water disinfection. Filtration, including microfiltration, ultrafiltration, and reverse osmosis, is used to remove bacteria. In addition to chemical and filtration technologies, one can disinfect water using UV irradiation, ultrasonic treatment, electrolysis, solar disinfection, and slow sand filtration.
Currently, there are few solutions being employed in third world settings for communities. The current solutions are either for one household or are part of an existing infrastructure and therefore are not portable. Slow sand filtration is used successfully to provide potable water for individual households. Tablet …

Water Purification For Rural Communities Using Ultraviolet Light And Bleach Systems, Ryan Lee

Chemical Engineering Undergraduate Honors Theses

Many technologies are used for water disinfection. Chlorine, iodine, and ozone are some chemical methods of water disinfection. Filtration, including microfiltration, ultrafiltration, and reverse osmosis, is used to remove bacteria. In addition to chemical and filtration technologies, one can disinfect water using UV irradiation, ultrasonic treatment, electrolysis, solar disinfection, and slow sand filtration.
Currently, there are few solutions being employed in third world settings for communities. The current solutions are either for one household or are part of an existing infrastructure and therefore are not portable. Slow sand filtration is used successfully to provide potable water for individual households. Tablet …

Innovation And Development Of Biofuel Technologies, Nicole Lorenz

Chemical Engineering Undergraduate Honors Theses

The need for viable alternatives to gasoline has lead researchers to explore various options for renewable energy resources. This research study focuses on two major options for renewable energy. The first is biodiesel, which is a fuel that can be made from vegetable oils or animal fats. In this study, biodiesel was made from tall oil, a paper byproduct. A novel reaction method was used, employing high temperature methanol rather than acid or base catalysis. The second option that was investigated is butanol, which is an alcohol with advantages over ethanol. First, a two-step fermentation was examined to improve the …

Non-Natural Protein Mimetics For The Treatment Of Alzheimer's Disease, Jennifer Herrera, Amanada Compean, Jasmine Brown, Melissa Moss, Shannon Servoss

Chemical Engineering Undergraduate Honors Theses

Alzheimer's disease (AD) is a slow degenerative disease that causes memory loss and eventually leads to death. AD is caused by the aggregation of the amyloid-beta protein, found on the outside of brain cells; once the amyloid-beta protein begins to aggregate it forms plaques on the extracellular part of the neural cells. To date there is no AD medication commercially available that breaks up the amyloid-beta aggregates. Current research has found that certain molecules bind to the amyloid-beta protein and prevent aggregation. The purpose of this research project is to engineer a peptoid-based molecule to stop the aggregation of the …

Biokinetic Mechanisms Linked With Musculoskeletal Health Disparities: Stochastic Models Applying Tikhonov's Theorem To Biomolecule Homeostasis., Asit K. Saha, Yu Liang, Sean S. Kohles

Mechanical and Materials Engineering Faculty Publications and Presentations

Multiscale technology and advanced mathematical models have been developed to control and characterize physicochemical interactions, respectively, enhancing cellular and molecular engineering progress. Ongoing tissue engineering development studies have provided experimental input for biokinetic models examining the influence of static or dynamic mechanical stimuli (Saha, A. K., and Kohles, S. S., 2010, “A Distinct Catabolic to Anabolic Threshold Due to Single-Cell Nanomechanical Stimulation in a Cartilage Biokinetics Model,” J. Nanotechnol. Eng. Med., 1(3) p. 031005; 2010, “Periodic Nanomechanical Stimulation in a Biokinetics Model Identifying Anabolic and Catabolic Pathways Associated With Cartilage Matrix Homeostasis,” J. Nanotechnol. Eng. Med., 1(4), p. 041001). In …

Ontology For Psychophysiological Dysregulation Of Anger/Aggression, Swathi Vasanthapuram

School of Computing: Dissertations, Theses, and Student Research

The advancement of Information Technology in the last four decades led to the use of computers in medicine. A new area called Medical Informatics has emerged. This area comprises the application of IT to healthcare with the aim of creating tools that help healthcare personnel diagnose and treat patients more accurately and efficiently. IT not only provides tools for storing, integrating, and updating patient information base but also for processing information efficiently. One of such tools is a Clinical Decision Support System. Ontologies are an integral part of clinical decision support systems because they help formalize and integrate domain knowledge. …

Effect Of Heavy Metals Found In Flue Gas On Growth And Lipid Accumulation For Green Algae Scenedesmus Obliquus, Reece Butler

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

In recent years there has been a growing interest within the United States to replace fossil fuels with biofuels for environmental and national security reasons. Algal feedstocks have the potential of producing significantly higher yields of oil for biofuels than any other source. It is well known that high concentrations of CO₂ can increase algal yields. Flue gas from coal fire power plants is an obvious source of CO₂. The flue gas, however, will contain other chemicals besides CO₂ that may not be beneficial to the algae. The research objectives for this study were to determine …

Algal Biofilm Production And Harvesting System For Wastewater Treatment With Biofuels By-Products, Logan Christenson

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Excess nitrogen and phosphorus in discharged wastewaters can lead to downstream eutrophication, ecosystem damage, and impaired water quality that may affect human health. Chemical-based and physical-based technologies are available to remove these nutrients; however, they often consume significant amounts of energy and chemicals, greatly increasing treatment costs. Algae are capable of removing these pollutants through biomass assimilation, and if harvested, can be utilized as a feedstock for biomethane or biodiesel production. Currently, difficulties in harvesting, concentrating, and dewatering algae have limited the development of an economically feasible treatment and production process. When algae are grown as surface-attached biofilms, the biomass …

Assessing Phosphorus-Transport From Biosolids Land Application Sites In Utah, Mohan K. Kumar

All Graduate Plan B and other Reports, Spring 1920 to Spring 2023

Phosphorus Site Index (PSI) is a phosphorus transport assessment tool used to estimate the risk of P transport from soils. Various components, such as soil erosion, P fertilizer application rate, plant available P in soil, etc. that have an influence on P transport from a site, are weighted and given ratings, and a combination of these components are expressed as PSI. This study has considered two biosolids land application sites in Utah, which received biosolids amendments over time, to develop a specialized PSI for the state of Utah.

Phosphorus from land application of biosolids has been considered a potential risk …

Simple And Appropriate Methods For Household Water Treatment, Morris Elya Demitry

All Graduate Plan B and other Reports, Spring 1920 to Spring 2023

Shortage of drinking water is the big challenge for Sudan. The cost of water treatment is the main reason for using untreated water for drinking purposes in many urban areas in Sudan. Water born‐diseases (diarrhea, typhoid, etc) are common and there are many victims in unimproved urban areas in Khartoum (Sudan) due to poor or the lack of treatment of drinking water.

In this work, a simple and appropriate method (sand filter) for household water treatment was tested and developed. The main objective of using this method is to help people in urban areas without access to treated water to …

Combating Antibiotic Resistance Through Development Of A Novel Antimicrobial Delivery Vehicle, Alex Hatch

Undergraduate Honors Capstone Projects

A thermoreversible gel for antimicrobial agent delivery would provide a novel platform suitable for medical applications from persistent infections arising from localized biofilms. Thermoreversible gels could be used to coat medical implants, to inject for subdermal treatments, or to implement in topical applications. FDA approved Pluronics® form thermoreversible gels and certain Pluronics® display inherent varying degrees of antimicrobial activity. Pluronics® have been shown to affect efflux pumps, and reduce ATP levels within the bacterial cell. In combination with antibiotics and other pharmaceuticals, Pluronics® have been used to sequester drugs and act as a delivery vehicle. With advances in nanomedicine, nanoparticles …

Comparative Studies On Scale-Up Methods Of Single-Use Bioreactors, Emily B. Stoker

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

This study was performed to increase knowledge of oxygen mass transfer (kLa) and mixing times in the scale-up of disposable bioreactors.Results of oxygen mass transfer studies showed kLa to increase with increasing agitation and aeration rates. By maintaining a scale-up constant such as gassed power to volume or shear, an almost constant k_La was achieved during scale-up from 50 to 2000 L. Using the scale-up constant P_g/V resulted in statistically higher kLa values at greater reactor volumes. Mixing times were revealed to be significantly affected by agitation, but not by the aeration rates tested. No pattern …

Fluoro-Silane As A Functional Monomer For Protein Conformational Imprinting, Yun Peng

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

By using the technology of molecularly imprinted polymer (MIP), we propose to synthesize a protein conformational imprint that also acts as a plastic enzyme, inducing protein structural transitions. The imprint aims at MIP-induced stabilization and / or formation of bound protein secondary structure and the applications associated with analysis and correction of misfolded proteins. The screening of polymeric functional monomers being able to induce the conformational transitions in proteins is investigated in this report.

The fluoro-silanes (3-heptafluoroisopropoxy)propalethoxysilane (7F) and 3,3,3-trifluoropropylmethoxysilane (3F) were employed as functional monomers for synthesis of this catalytic protein conformational imprint via sol-gel reactions. 3F was demonstrated …

Variability Of Water Storage And Instream Temperature In Beaded Arctic Streams, Madeline F. Merck

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The purpose of this study is to investigate variation in water export and instream temperatures throughout the open water season in a beaded Arctic stream, consisting of small pools connected by shallow chutes. The goals are to better understand heat and mass movement through these systems, how this may impact chemical and biological processes, and the resulting shifts with changes in climate. This is accomplished by first examining the extent and variability of water storage and export through qualitative analysis of observational data. Further, heat fate and transport is examined through development of an instream temperature model. The model formulation, …

Characterization And Application Of Dynamic In Vitro Models Of Human Airway, Hemangkumar J. Patel

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

In recent years, respiratory diseases have emerged as a leading cause of mortality across the globe. In the United States alone respiratory diseases are the fourth leading cause of deaths annually. Moreover, with the rapid increase of industrialization and urbanization, the occurrences of respiratory diseases are expected to remain high with strong chances of increasing in the future. To ameliorate the epidemic of respiratory disease, it is first important to understand its underlying mechanisms.

Respiratory research studies in animals have elucidated the chronological order of the pathological events and systemic responses inside the lung, but understanding the response of individual …

A Study On The Applications And Toxicity Assessments Of Carbon Nanotubes In Tissue Engineering, Rena Baktur

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Carbon nanotubes (CNTs) are one of the most popular nanomaterials. There has been increasing interest in the development and applications of carbon nanotubes due to their huge potential in industrial and medical applications. Recent applications of carbon nanotubes include development of scaffolds and drug delivery systems. Despite rapidly emerging applications of CNTs, little is known about the impact of CNTs on cellular processes, especially mesenchymal stem cell (MSC)'s differentiation. Also, the effects of nanoparticle exposure under different conditions on cellular responses have not been well characterized yet.

To characterize the effects of CNTs on creating nanoscale scaffolds for tissue engineering, …

Perching Using A Quadrotor With Onboard Sensing, Jeremy C. Goldin

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

This thesis presents an implementation of autonomous indoor perching using only onboard sensors on a low-cost, custom-built quadrotor. The perching aggressive maneuver is representative of a class of control problems for aerobatics that requires an agile and robust control system for maneuvering accurately at high speeds. Such research extends the typical functionality of micro air vehicles (MAV) from low speed and stationary observation to dynamic aerobatic transitions for broader operational capabilities including confined landings and evasive maneuvering. To achieve this, three major challenges are overcome: precise and real-time positioning, sensing of the perch and path to the perch, and control …

Salen Mn Complexes Mitigate Radiation Injury In Normal Tissues, Rosalind A. Rosenthal, Brian Fish, Richard P. Hill, Karl D. Huffman, Zelmira Lazarova, Javed Mahmood, Meetha Medhora, Robert C. Molthen, John E. Moulder, Stephen T. Sonis, Philip J. Tofilon, Susan R. Doctrow

Biomedical Engineering Faculty Research and Publications

Salen Mn complexes, including EUK-134, EUK-189 and a newer cyclized analog EUK-207, are synthetic SOD/catalase mimetics that have beneficial effects in many models of oxidative stress. As oxidative stress is implicated in some forms of delayed radiation injury, we are investigating whether these compounds can mitigate injury to normal tissues caused by ionizing radiation. This review describes some of this research, focusing on several tissues of therapeutic interest, namely kidney, lung, skin, and oral mucosa. These studies have demonstrated suppression of delayed radiation injury in animals treated with EUK-189 and/or EUK-207. While an antioxidant mechanism of action is postulated, it …

Modeling And Optimization Of Stochastic Process Parameters In Complex Engineering Systems, Paul Goethals

All Dissertations

For quality engineering researchers and practitioners, a wide number of statistical tools and techniques are available for use in the manufacturing industry. The objective or goal in applying these tools has always been to improve or optimize a product or process in terms of efficiency, production cost, or product quality. While tremendous progress has been made in the design of quality optimization models, there remains a significant gap between existing research and the needs of the industrial community. Contemporary manufacturing processes are inherently more complex - they may involve multiple stages of production or require the assessment of multiple quality …

Methods Development And Force Field Evaluation For Molecular Simulations Of Interactions Between Structured Peptides And Functionalized Material Surfaces, Galen Collier

All Dissertations

The process of protein adsorption to material surfaces is highly complex and it is one of the most fundamental concepts upon which progress in the field of bioengineering is based. The strategic design of material surfaces for optimal utility in specific biological environments is absolutely dependent upon a thorough understanding of the mechanisms underlying protein adsorption, yet there is still a very limited understanding of these mechanisms. The primary reason for this lack of understanding is that protein adsorption is a dynamic process which occurs at the atomic and macromolecular scale, where experimental analyses provide a view that is static …

Implementation Of Delayed-Feedback Controllers On Continuous Systems And Analysis Of Their Response Under Primary Resonance Excitations, Yousef Qaroush

All Dissertations

During the last three decades, a considerable amount of research has been directed toward understanding the influence of time delays on the stability and stabilization
of dynamical systems. From a control perspective, these delays can either have a compounding and destabilizing effect, or can actually improve controllers'
performance. In the latter case, additional time delay is carefully and deliberately introduced into the feedback loop so as to augment inherent system delays and
produce larger damping for smaller control efforts. While delayed-feedback algorithms have been successfully implemented on discrete dynamical systems with
limited degrees of freedom, a critical issue appears in …

Novel Nanofiber Structures And Advanced Tissue Engineering Applications, Vince Beachley

All Dissertations

Extracellular matrix (ECM) nanofibers such as collagen and elastin make up an important component of natural tissues. These structural components serve to impart mechanical strength and provide locations for cell attachment and biomolecule storage. Cells respond to their structural environment in a wide variety of ways beyond physical support, and it has been demonstrated that this environment directly modulates cell behaviors such as, morphology, differentiation, ECM production, attachment, and migration. ECM nanofibers also play an important role as a template for tissue formation during development, remodeling, and regeneration. Nanofiber based tissue engineering strategies aim to mimic the geometry of the …

Comparative Fecal Metagenomics Unveils Unique Functional Capacity Of The Swine Gut, Regina Lamendella, Jorge W. Santo Domingo, Shreya Ghosh, John Martinson, Daniel B. Oerther

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

Background: Uncovering the taxonomic composition and functional capacity within the swine gut microbial consortia is of great importance to animal physiology and health as well as to food and water safety due to the presence of human pathogens in pig feces. Nonetheless, limited information on the functional diversity of the swine gut microbiome is available. Results: Analysis of 637, 722 pyrosequencing reads (130 megabases) generated from Yorkshire pig fecal DNA extracts was performed to help better understand the microbial diversity and largely unknown functional capacity of the swine gut microbiome. Swine fecal metagenomic sequences were annotated using both MG-RAST and …