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The Geographic Disparities In Transportation-Related Physical Activity In The United States: An Analysis Of The 2017 Nhts Data, Hongwei Dong Apr 2020

The Geographic Disparities In Transportation-Related Physical Activity In The United States: An Analysis Of The 2017 Nhts Data, Hongwei Dong

Mineta Transportation Institute

Research on the relationship between urbanicity and physical activity yielded mixed results despite many studies consistently showing that residents tended to undertake more transportation-related physical activity in a more urban environment. This study analyzed the 2017 NHTS data to examine the geographic disparities in physical activity, particularly transportation-related physical activity in the United States. Our analysis suggests the relationship between urbanicity and physical activity demonstrates a flat U-shape in graphed data. Residents are more physically active when they live in the areas from the two ends of the urbanization spectrum: inner cities and inner suburbs of large metropolitan areas and …


Role Of Thyroid Hormone Modulating Astrocyte Activation, Payal Ghosh Mar 2020

Role Of Thyroid Hormone Modulating Astrocyte Activation, Payal Ghosh

USF Tampa Graduate Theses and Dissertations

Astrocytes are the specialized cells in the central nervous system (CNS). They play an important role in neuronal homeostasis. When activated, astrocytes may cause neuronal inflammation and degeneration. Thyroid hormones are important in maintaining neuronal development and homeostasis. Astrocytes play a pivotal role in this process. However, the role of levothyroxine (T4) in neuroinflammation is not clear. It is hypothesized that thyroid hormone treatment will reduce the inflammatory activation in astrocytes. Available oral T4 supplementations allow accumulation of T4 in the body and cause toxicity and side effects. It is hypothesized that the encapsulation of T4 in liposomes would reduce …


Space And Defense – Volume Nine – Number One – Spring 2016, Space And Defense Journal Mar 2020

Space And Defense – Volume Nine – Number One – Spring 2016, Space And Defense Journal

Space and Defense

No abstract provided.


Multivariate Analysis Of Human Performance Strong Lab Data, Kayla N. Tinucci Mar 2020

Multivariate Analysis Of Human Performance Strong Lab Data, Kayla N. Tinucci

Theses and Dissertations

This study uses multivariate analysis methods to find relationships between nutrition and wellness and nutrition and performance. The nutrition, daily wellness, and weight and bodyfat data are from a study performed by the STRONG lab in the 711th Human Performance Wing. Electronically collected nutrition data along with survey data for 19 individuals over a 12-week study period are examined with a focus on health, fitness, and nutrition. Factor analysis and linear regression are performed and inferences are drawn regarding what effects calories and macronutrient intake have on subjects perceived wellness, weight, and body fat percentage. These insights are discussed in …


Barriers And Facilitators Influencing Compliance With Enhanced Recovery After Surgery Protocol: A Qualitative Study, Paige Boudreaux Mar 2020

Barriers And Facilitators Influencing Compliance With Enhanced Recovery After Surgery Protocol: A Qualitative Study, Paige Boudreaux

LSU Master's Theses

Standardization in many industries has proven to lead to improved productivity and efficiency, however, standard practice in healthcare has proven difficult due to patient and physician variation. Evidence-based practices provide an opportunity to create more standardization. Enhanced Recovery After Surgery (ERAS) programs are attempting to standardize the surgical pathways of patients by implementing standard evidence-based steps, beginning in the surgeons office and continuing through a patients discharge (Ljungqvist, Scott, & Fearon, 2017). Implementing ERAS to standardize the surgical care of patients has shown to improve patient outcomes, reduce length of stay and reduce readmissions, however, there is a lack of …


Transcutaneous Auricular Vagus Nerve Stimulation-Paired Rehabilitation For Oromotor Feeding Problems In Newborns: An Open-Label Pilot Study, Bashar W. Badran, Dorothea D. Jenkins, Daniel Cook, Sean Thompson, Morgan Darcy, William H. Devries, Georgia Mappin, Philipp Summers, Marom Bikson, Mark S. George Mar 2020

Transcutaneous Auricular Vagus Nerve Stimulation-Paired Rehabilitation For Oromotor Feeding Problems In Newborns: An Open-Label Pilot Study, Bashar W. Badran, Dorothea D. Jenkins, Daniel Cook, Sean Thompson, Morgan Darcy, William H. Devries, Georgia Mappin, Philipp Summers, Marom Bikson, Mark S. George

Publications and Research

Neonates born premature or who suffer brain injury at birth often have oral feeding dysfunction and do not meet oral intake requirements needed for discharge. Low oral intake volumes result in extended stays in the hospital (>2 months) and can lead to surgical implant and explant of a gastrostomy tube (G-tube). Prior work suggests pairing vagus nerve stimulation (VNS) with motor activity accelerates functional improvements after stroke, and transcutaneous auricular VNS (taVNS) has emerged as promising noninvasive form of VNS. Pairing taVNS with bottle-feeding rehabilitation may improve oromotor coordination and lead to improved oral intake volumes, ultimately avoiding the …


2020 Oklahoma Research Day Full Program, Southwestern Oklahoma State University Mar 2020

2020 Oklahoma Research Day Full Program, Southwestern Oklahoma State University

Oklahoma Research Day Abstracts

No abstract provided.


Inverse Dynamics Analysis Of Youth Pitching Arm Kinetics Using Body Composition Imaging, Jay A. Sterner, Scott K. Reaves, Arnel L. Aguinaldo, Scott Hazelwood, Stephen M. Klisch Mar 2020

Inverse Dynamics Analysis Of Youth Pitching Arm Kinetics Using Body Composition Imaging, Jay A. Sterner, Scott K. Reaves, Arnel L. Aguinaldo, Scott Hazelwood, Stephen M. Klisch

Biomedical Engineering

This study’s objectives were to: (1) assess whether dual energy X-ray absorptiometry (DXA)-mass inverse dynamics (ID) alters predictions of youth pitching arm kinetics and (2) investigate correlations between kinetics and body composition. Eighteen 10- to 11-year-olds pitched 10 fastballs. DXA scans were conducted to obtain participant-specific upper arm, forearm, and hand masses. Pitching arm segment masses and kinetics calculated with scaled and DXA masses were compared with paired t-tests and correlations were investigated with linear regression. Hand (p < 0.001) and upper arm (p < 0.001) DXA masses were greater, while forearm (p < 0.001) DXA masses were lesser, than their scaled masses. Shoulder compressive force (p < 0.001), internal rotation torque (p < 0.001), and horizontal adduction torque (p = 0.002) increased when using DXA masses. Shoulder compressive force correlated with body mass (p < 0.001) and body mass index (BMI; p = 0.002) and elbow varus torque correlated with body mass (p < 0.05). The main conclusions were that (1) using participant-specific mass ratios leads to different predictions of injury-related pitching arm kinetics and, thus, may improve our understanding of injury risk factors; and (2) pitching arm kinetics were correlated with body composition measures and a relatively high total body mass and/or BMI may increase shoulder and/or elbow injury risk.


Theoretical Analysis Of The Leakage Through The Cement Line Of A Single Osteon, Gaffar Gailani, Stephen Cowin Mar 2020

Theoretical Analysis Of The Leakage Through The Cement Line Of A Single Osteon, Gaffar Gailani, Stephen Cowin

Publications and Research

This work focuses on the Lacunar–Canalicular Porosity (PLC) of cortical bone which includes the osteons. Osteons are semicylindrical porous structures saturated with fluid within the bone and are approximately 250" role="presentation">μ" role="presentation">μm in diameter. The outer boundary of the osteon is called the cement line. Some studies suggested that the cement line is less highly mineralized and produced evidence that it has less calcium and phosphorus and more sulfur than the neighboring bone lamellae. Most authors assume that the cement line is impermeable, while others assume that some canaliculi are crossing the cement line which will make it …


The Effect Of Aeration Rate And Free-Floating Carrier Media On The Emission Of Bacillus Globigii In Bioaerosols, Andrew J. Owens Mar 2020

The Effect Of Aeration Rate And Free-Floating Carrier Media On The Emission Of Bacillus Globigii In Bioaerosols, Andrew J. Owens

Theses and Dissertations

Aerosols produced by turbulent mechanical mixing and bubble aeration at Waste Water Treatment Plants (WWTPs) become bioaerosols with the entrainment of biological materials. Bioaerosols become a public health risk when human pathogens are present. This study evaluated bioaerosols containing Bacillus globigii (BG) spores, and the effects that aeration rate and the addition of Free-Floating Carrier Media (FFCM) had on the amount of BG spores collected following aerosolization. A series of laboratory-scale experiments investigated two different sizes of floating polystyrene spheres as FFCM and four different aeration rates. When the differences in compared aeration rates were sufficiently large, a positive correlation …


Examining Healthy Community Design Characteristics And Its Influence On Physical Health, Alvin T. Yip Mar 2020

Examining Healthy Community Design Characteristics And Its Influence On Physical Health, Alvin T. Yip

Theses and Dissertations

Current trends in obesity rates associated with the community layout constitutes research towards understanding the interaction between the two in order to improve the public's physical health. Successes in healthy community planning studies for the public can be harnessed and implemented within the microcosm of military bases to yield similar results. Four factors were recognized through an in-depth academic literature review that showed positive influence on physical health and physical activity. They are access to green space, highly connected pedestrian and bicycle networks, access to public transportation, and integrated mixed land use. The four healthy planning strategies formed the necessary …


Assessing The Equity Gap In Construction Education, Jared M. Burgoon, John Killingsworth, Jonathan W. Elliott, Molly M. Weisshaar Mar 2020

Assessing The Equity Gap In Construction Education, Jared M. Burgoon, John Killingsworth, Jonathan W. Elliott, Molly M. Weisshaar

The Professional Constructor

There is a documented demand for an educated construction management workforce. To help meet this demand, construction education programs at numerous post-secondary institutions have established objectives and goals to recruit, train, and graduate high-quality students; and, many of these programs are charged with providing educational opportunities to students who have been traditionally underserved in higher education (e.g., female, minority, first generation students, etc.). This study compared the enrollment and retention rates, interdepartmental migration patterns, and student satisfaction and graduation success outcomes of undergraduate students enrolled in a CM program at a public university as a means of identifying trends and …


Methods To Increase Algae Biomass Productivity In Raceway Pond Monocultures, Ryan S. Anderson Mar 2020

Methods To Increase Algae Biomass Productivity In Raceway Pond Monocultures, Ryan S. Anderson

Master's Theses

The economics of algae biofuels and bioproducts would be improved by increased biomass productivity. Two studies on this potential are described in this thesis – one on a locally isolated filamentous yellow-green alga and the other on a planktonic strain genetically improved via selective enrichment.

Polycultures have been viewed as productive, stable, and, in some cases, harvestable by natural bioflocculation. Local native strains might have higher productivity than culture collection strains because they are already adapted to local outdoor conditions. In this study, the filamentous yellow-green alga Tribonema minus was isolated from a local volunteer polyculture. Its productivity as a …


Use Of Body Composition Imaging To Calculate 3-D Inertial Parameters For Inverse Dynamic Analysis Of Youth Pitching Arm Kinetics, Dalton James Jennings Mar 2020

Use Of Body Composition Imaging To Calculate 3-D Inertial Parameters For Inverse Dynamic Analysis Of Youth Pitching Arm Kinetics, Dalton James Jennings

Master's Theses

The objectives of this study were to 1) calculate participant-specific segment inertial parameters using dual energy X-ray absorptiometry (DXA) data (referred to as full DXA-driven parameters) and compare the pitching arm kinetic predictions using full DXA-driven inverse dynamics vs scaled, DXA mass-driven (using DXA masses but scaled centers of mass and radii of gyration), and DXA scaled inverse dynamics(ID) (using the full DXA-driven inertial parameters averaged across all participants), 2) examine associations between full DXA-driven kinetics and body mass index (BMI) and 3) examine associations between full DXA-driven kinetics and segment mass index (SMI). Eighteen 10- to 11- year-olds pitched …


Initial Development Of Corn Seedlings After Seed Priming With Nanoscale Synthetic Zinc Oxide, Michel Esper Neto, David W. Britt, Lorena Moreira Lara, Anthony Cartwright, Rayssa Fernanda De Santos, Tadeu Takeyoshi Inoue, Marcelo Augusto Batista Feb 2020

Initial Development Of Corn Seedlings After Seed Priming With Nanoscale Synthetic Zinc Oxide, Michel Esper Neto, David W. Britt, Lorena Moreira Lara, Anthony Cartwright, Rayssa Fernanda De Santos, Tadeu Takeyoshi Inoue, Marcelo Augusto Batista

Biological Engineering Faculty Publications

Nanofertilizers are increasingly explored for sustainable micronutrient delivery in agriculture. Pre-treating seeds with nanofertilizers prior to planting (i.e., seed priming) reduces concerns about nanoparticle (NP) fertilizer non-target dispersion; however, priming formulations and concentrations must be carefully selected to avoid germination inhibition and toxicity. Here we investigate changes in corn seed germination and seedling development after seed priming with ZnO NPs, ZnO bulk and ZnCl2. To evaluate the effects sterile seeds were immersed in priming solutions of 0, 20, 40, 80, 160 mg L−1 Zn for the three Zn sources. Following an 8 h priming the seeds were …


Sustainable, Alginate-Based Sensor For Detection Of Escherichia Coli In Human Breast Milk, Nicholas Kikuchi, Margaret May, Matthew Zweber, Jerard Madamba, Craig M. Stephens, Unyoung Kim, Maryam Mobed-Miremadi Feb 2020

Sustainable, Alginate-Based Sensor For Detection Of Escherichia Coli In Human Breast Milk, Nicholas Kikuchi, Margaret May, Matthew Zweber, Jerard Madamba, Craig M. Stephens, Unyoung Kim, Maryam Mobed-Miremadi

Bioengineering

There are no existing affordable diagnostics for sensitive, rapid, and on-site detection of pathogens in milk. To this end, an on-site colorimetric-based sustainable assay has been developed and optimized using an L16 (54) Taguchi design to obtain results in hours without PCR amplification. To determine the level of Escherichia coli (E. coli) contamination, after induction with 150 µL of breast milk, the B-Per bacterial protein extraction kit was added to a solution containing an alginate-based microcapsule assay. Within this 3 mm spherical novel sensor design, X-Gal (5-Bromo-4-Chloro-3-Indolyl β-D-Galactopyranoside) was entrapped at a concentration of 2 …


Protein-Polysaccharide Composite Materials: Fabrication And Applications., Elizabeth J Bealer, Shola Onissema-Karimu, Ashley Rivera-Galletti, Maura Francis, Jason Wilkowski, David Salas-De La Cruz, Xiao Hu Feb 2020

Protein-Polysaccharide Composite Materials: Fabrication And Applications., Elizabeth J Bealer, Shola Onissema-Karimu, Ashley Rivera-Galletti, Maura Francis, Jason Wilkowski, David Salas-De La Cruz, Xiao Hu

College of Science & Mathematics Departmental Research

Protein-polysaccharide composites have been known to show a wide range of applications in biomedical and green chemical fields. These composites have been fabricated into a variety of forms, such as films, fibers, particles, and gels, dependent upon their specific applications. Post treatments of these composites, such as enhancing chemical and physical changes, have been shown to favorably alter their structure and properties, allowing for specificity of medical treatments. Protein-polysaccharide composite materials introduce many opportunities to improve biological functions and contemporary technological functions. Current applications involving the replication of artificial tissues in tissue regeneration, wound therapy, effective drug delivery systems, and …


Brain Health Innovation Diplomacy: A Model Binding Diverse Disciplines To Manage The Promise And Perils Of Technological Innovation, Kylie Ternes, Vijeth Iyengar, Helen Lavretsky, Walter D. Dawson, Laura Booi, Agustin Ibanez, Ipsit Vahia, Charles Reynolds, Steven Dekosky, Jeffrey Cummings, Bruce Miller, Carla Perissinotto, Jeffrey Kaye, Harris A. Eyre Feb 2020

Brain Health Innovation Diplomacy: A Model Binding Diverse Disciplines To Manage The Promise And Perils Of Technological Innovation, Kylie Ternes, Vijeth Iyengar, Helen Lavretsky, Walter D. Dawson, Laura Booi, Agustin Ibanez, Ipsit Vahia, Charles Reynolds, Steven Dekosky, Jeffrey Cummings, Bruce Miller, Carla Perissinotto, Jeffrey Kaye, Harris A. Eyre

School of Medicine Faculty Research

Background: Brain health diplomacy aims to influence the global policy environment for brain health (i.e. dementia, depression, and other mind/brain disorders) and bridges the disciplines of global brain health, international affairs, management, law, and economics. Determinants of brain health include educational attainment, diet, access to health care, physical activity, social support, and environmental exposures, as well as chronic brain disorders and treatment. Global challenges associated with these determinants include large-scale conflicts and consequent mass migration, chemical contaminants, air quality, socioeconomic status, climate change, and global population aging. Given the rapidly advancing technological innovations impacting brain health, it is paramount to …


Crowdprivacy: Publish More Useful Data With Less Privacy Exposure In Crowdsourced Location-Based Services, Fang Jing Wu, Tie Luo Feb 2020

Crowdprivacy: Publish More Useful Data With Less Privacy Exposure In Crowdsourced Location-Based Services, Fang Jing Wu, Tie Luo

Computer Science Faculty Research & Creative Works

Location-based services (LBSs) typically crowdsource geo-tagged data from mobile users. Collecting more data will generally improve the utility for LBS providers; however, it also leads to more privacy exposure of users' mobility patterns. Although the tension between data utility and user privacy has been recognized, there lacks a solution that determines how much data to collect-in both spatial and temporal domains-is the "best" for both mobile users and the service provider. This article proposes a strategy toward making an optimal tradeoff such that a user submits data only if her mobility privacy will not be compromised and the data utility …


Sick Buildings, Poor Design And Public Heath, Dalia Shebl Said, Yasmin Shebl Said Jan 2020

Sick Buildings, Poor Design And Public Heath, Dalia Shebl Said, Yasmin Shebl Said

Architecture and Planning Journal (APJ)

There is no doubt that there is a close relationship between health problems and housing conditions. According to the World Health Organization (WHO) estimates in developing countries those 2 million early and unexpected deaths, with close to half occurring among children less than 5 years old die from indoor air pollution and bad housing. Housing is an important determinant of health, and substandard housing is a major public health issue. Designing and bad orientation of housing are found to have significant effects on poor respiratory health especially in children, and increase an infectious disease thereby putting them at higher risk …


Experimental And Computational Tools For Single Cell Analysis In Cancer Diagnostics, Manibarathi Vaithiyanathan Jan 2020

Experimental And Computational Tools For Single Cell Analysis In Cancer Diagnostics, Manibarathi Vaithiyanathan

LSU Doctoral Dissertations

Substantial evidence shows that cellular heterogeneity commonly exists within an isogenic or clonal population. Whether in isolation or caused through a combination of the above events, cellular heterogeneity can dramatically influence cellular decision making and cell fate, however, this can be masked by the average response from a population. One approach to solve this issue is to analyze a population at the individual cell level. The goal of this work is to develop high-throughput experimental and computational platforms to screen and quantify single cancer cells for specific intracellular enzyme activities. An interdisciplinary approach was taken to 1) better understand the …


Congressional Committee Resources On Space Policy During The 115th Congress (2017-2018): Providing Context And Insight Into U.S. Government Space Policy, Bert Chapman Jan 2020

Congressional Committee Resources On Space Policy During The 115th Congress (2017-2018): Providing Context And Insight Into U.S. Government Space Policy, Bert Chapman

Libraries Faculty and Staff Scholarship and Research

Article 1 of the US Constitution assigns the US Congress numerous responsibilities. These include creating new laws, revising existing laws, funding government programs, and conducting oversight of these programs' performance. Oversight of US Government agency space policy programs is executed by various congressional space policy committees, including the House and Senate Science Committees, Armed Services, and Appropriations Committees. These committees conduct many public hearings on space policy which invite witnesses to testify on US space policy programs and feature debate on the strengths and weaknesses of these programs. Documentation produced by these committees is widely available to the public, except …


Bioadhesive Hydrogel Composite Cell Carrier For The Repair Of The Degenerated Intervertebral Disc, Thomas Richard Christiani Jan 2020

Bioadhesive Hydrogel Composite Cell Carrier For The Repair Of The Degenerated Intervertebral Disc, Thomas Richard Christiani

Theses and Dissertations

Lower back pain (LBP) affects the worldwide population and can be attributed to the degeneration of the intervertebral disc (IVD). The IVD is composed of a central nucleus pulposus (NP), a peripheral annulus fibrosus (AF), and adjacent cartilage endplates (CEPs). IVD degeneration is characterized by proteoglycan loss, tissue dehydration, and decreased hydrostatic pressure. In this work, the use of an injectable bioadhesive hydrogel composite for replacement of the degenerated NP was investigated.

Results indicate that the composite exhibits similar mechanical properties to the NP, adheres to AF tissue, and supports encapsulated mesenchymal stem cell (MSC) differentiation toward an NP-like phenotype …


Optfill: A Tool For Infeasible Cycle-Free Gapfilling Of Stoichiometric Metabolic Models, Wheaton L. Schroeder, Rajib Saha Jan 2020

Optfill: A Tool For Infeasible Cycle-Free Gapfilling Of Stoichiometric Metabolic Models, Wheaton L. Schroeder, Rajib Saha

Mid-America Transportation Center: Final Reports and Technical Briefs

Stoichiometric metabolic modeling, particularly genome-scale models (GSMs), is now an indispens- able tool for systems biology. The model reconstruction process typically involves collecting informa- tion from public databases; however, incomplete systems knowledge leaves gaps in any reconstruc- tion. Current tools for addressing gaps use databases of biochemical functionalities to address gaps on a per-metabolite basis and can provide multiple solutions but cannot avoid thermodynami- cally infeasible cycles (TICs), invariably requiring lengthy manual curation. To address these limita- tions, this work introduces an optimization-based multi-step method named OptFill, which performs TIC-avoiding whole-model gapfilling. We applied OptFill to three fictional prokaryotic models …


Treenuts And Groundnuts In The Eat-Lancet Reference Diet: Concerns Regarding Sustainable Water Use, Davy Vanhama, Mesfin Mekonnen, Arjen Y. Hoekstra Jan 2020

Treenuts And Groundnuts In The Eat-Lancet Reference Diet: Concerns Regarding Sustainable Water Use, Davy Vanhama, Mesfin Mekonnen, Arjen Y. Hoekstra

Daugherty Water for Food Global Institute: Faculty Publications

The EAT-Lancet universal healthy reference diet recommends an increase in the consumption of healthy foods, among which treenuts and groundnuts. Both are, however, water-intensive products, with a large water footprint (WF) per unit of mass and protein and already today contribute to blue water stress in different parts of the world. The envisaged massive required increase in nut production to feed a global population with this reference diet, needs to occur in a water-sustainable way. In this paper, we identify and quantify where current nut production contributes to local blue water stress and discuss options for water-sustainable nut production. We …


Potential Of Using Spectral Vegetation Indices For Corn Green Biomass Estimation Based On Their Relationship With The Photosynthetic Vegetation Sub-Pixel Fraction, Luan Peroni Venancio, Everardo Chartuni Mantovani, Cibele Hummel Do Amaral, Christopher M.U. Neale, Ivo Zution Gonçalves, Roberto Filgueiras, Fernando Coelho Eugenio Jan 2020

Potential Of Using Spectral Vegetation Indices For Corn Green Biomass Estimation Based On Their Relationship With The Photosynthetic Vegetation Sub-Pixel Fraction, Luan Peroni Venancio, Everardo Chartuni Mantovani, Cibele Hummel Do Amaral, Christopher M.U. Neale, Ivo Zution Gonçalves, Roberto Filgueiras, Fernando Coelho Eugenio

Daugherty Water for Food Global Institute: Faculty Publications

Crop biomass (Bio) is one of the most important parameters of a crop, and knowledge of it before harvest is essential to help farmers in their decision making. Both green and dry Bio can be estimated from vegetation spectral indices (VIs) because they have a close relationship with accumulated absorbed photosynthetically active radiation (APAR), which is proportional to total Bio. The aims of this study were to analyze the potential capacity of spectral vegetation indices in estimating corn green biomass based on their relationship with the photosynthetic vegetation sub-pixel fraction derived from spectral mixture analysis and to analyze the best …


Computational Modeling Of The Human Microbiome, Shomeek Chowdhury, Stephen S. Fong Jan 2020

Computational Modeling Of The Human Microbiome, Shomeek Chowdhury, Stephen S. Fong

Chemical and Life Science Engineering Publications

The impact of microorganisms on human health has long been acknowledged and studied, but recent advances in research methodologies have enabled a new systems-level perspective on the collections of microorganisms associated with humans, the human microbiome. Large-scale collaborative efforts such as the NIH Human Microbiome Project have sought to kick-start research on the human microbiome by providing foundational information on microbial composition based upon specific sites across the human body. Here, we focus on the four main anatomical sites of the human microbiome: gut, oral, skin, and vaginal, and provide information on site-specific background, experimental data, and computational modeling. Each …


Perceived Neighborhood: Preferences Versus Actualities, Saeed Moradi, Ali Nejat, Da Hu, Souparno Ghosh Jan 2020

Perceived Neighborhood: Preferences Versus Actualities, Saeed Moradi, Ali Nejat, Da Hu, Souparno Ghosh

Department of Statistics: Faculty Publications

Housing recovery plays a key role in the overall restoration of a community. A multitude of factors affect housing recovery, many of which are associated with interactions of residents with their perceived neighborhoods. Targeting perceived neighborhoods rather than administratively defined measures of land helps with devising recovery plans that could better address social preferences of the residents. However, such measures are commonly subject to collection of information via expensive and time-consuming surveys. The current research aims to contribute to the domain by exploring the relationship between perception of households of their neighborhood anchors (perceived anchors) and the anchors that exist …


Diurnal Patterns Of Gene Expression In The Dorsal Vagal Complex And The Central Nucleus Of The Amygdala - Non-Rhythm-Generating Brain Regions., Mary M Staehle, Sean O'Sullivan, Rajanikanth Vadigepalli, Kate F Kernan, Gregory E Gonye, Babatunde A Ogunnaike, James S Schwaber Jan 2020

Diurnal Patterns Of Gene Expression In The Dorsal Vagal Complex And The Central Nucleus Of The Amygdala - Non-Rhythm-Generating Brain Regions., Mary M Staehle, Sean O'Sullivan, Rajanikanth Vadigepalli, Kate F Kernan, Gregory E Gonye, Babatunde A Ogunnaike, James S Schwaber

Henry M. Rowan College of Engineering Departmental Research

Genes that establish the circadian clock have differential expression with respect to solar time in central and peripheral tissues. Here, we find circadian-time-induced differential expression in a large number of genes not associated with circadian rhythms in two brain regions lacking overt circadian function: the dorsal vagal complex (DVC) and the central nucleus of the amygdala (CeA). These regions primarily engage in autonomic, homeostatic, and emotional regulation. However, we find striking diurnal shifts in gene expression in these regions of male Sprague Dawley rats with no obvious patterns that could be attributed to function or region. These findings have implications …


Low Dose Uv-B Induced Keratinocyte Exosomes Protect Schwann Cells Against High Glucose Injury, Kartheek Pothana Jan 2020

Low Dose Uv-B Induced Keratinocyte Exosomes Protect Schwann Cells Against High Glucose Injury, Kartheek Pothana

Browse all Theses and Dissertations

In this study, we tested the protective effect of UV-B treated HG-HaCaT-Exos on Schwann cells (SCs) injured by HG (high glucose) model. At first, we determined the dose of UV-B radiation and the time for the release of HaCaT-Exos. Furthermore, the Schwann cells were injured through the HG model, isolated by ultracentrifugation from the HaCaT cell culture supernatant were co-incubated within the injured cells. It was found that UV-B treated HaCaT-Exos decrease apoptosis and increase the viability of injured SC by transferring miR-222 from HaCaT cells to them via exosomes, hence protecting them.