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Afci Quarterly Input – Unlv July 1 Through September 30, 2005, Harry Reid Center For Environmental Studies. Nuclear Science And Technology Division

Transmutation Research Program Reports (TRP)

Quarterly report highlighting research projects, activities and objectives of the Transmutation Research Program at the Nuclear Science & Technology Division, Harry Reid Research Center.The University of Nevada, Las Vegas supports the AFCI through research and development of technologies for economic and environmentally sound refinement of spent nuclear fuel. The UNLV program has four components: infrastructure, international collaboration, student-based research, and management and program support.

Cgmp Recombinant Fix For Iv And Oral Hemophilia B Therapy, William H. Velander Principal Investigator, Abramson Stephan Lead Investigator, Cooper Julian Lead Investigator, William Dernell Key Person, Mark Manning Lead Investigator, Michael Meagher Lead Investigator, Paul Mohanan Lead Investigator, Timothy Nichols Lead Investigator, Todd Swaanson Key Person, Kevin E. Van Cott

Department of Chemical and Biomolecular Engineering: Funded Proposals

Three specific aims are proposed: Specific Aim # 1. Process engineer and scale-up the recovery and purification of transgenic recombinant human Factor IX. The University of Nebraska-Lincoln Biological Process Development Facility will complete process development and scale-up, and produce clinical grade materials for preclinical studies. The endpoint is a proposed final product specification to help facilitate transfer to current Good Manufacturing Practices compliant production of clinical grade material to support an Investigational New Drug filing with the United States Food and Drug Administration (FDA) leading to clinical trials. Specific Aim #2. Characterize and formulate transgenic recombinant human Factor IX for …

Microbial Quality Of Runoff Following Land Application Of Cattle Manure And Swine Slurry, Jeanette A. Thurston-Enriquez, John E. Gilley, Bahman Eghball

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Concentrations of human health-related microorganisms in runoff from agricultural plots (0.75m x 2m) treated with fresh and aged cattle manure, swine slurry and no manure (control) were determined. Three consecutive simulated rainfall events, producing 35 mm rainfall and separated by 24 h, were carried out for each plot. Fecal indicator (Escherichia coli, enterococci, Clostridium perfringens and coliphage) loads released in rainfall runoff from plots treated with fresh cattle manure, aged cattle manure and swine slurry treatments ranged from 5.52 x 10⁵ to 4.36 x 10⁹, 3.92 x 10⁴ to 4.86 x 10⁸, and 9.63 …

A Novel Type Of All-Stainless Steel Plate Heat Exchanger, P. Sjödin, C. Wolfe, B. Wilhelmsson

Enhanced, Compact and Ultra-Compact Heat Exchangers: Science, Engineering and Technology

No abstract provided.

A Rotating Shallow Cone Evaporator, R.S. Jebson

Enhanced, Compact and Ultra-Compact Heat Exchangers: Science, Engineering and Technology

No abstract provided.

An Experimental Technique For Measurement Of Heat Generated During Bone Sawing, Hamid Khalili Parsa, Ger Reilly, Brendan Mccormack

Conference Papers

Orthopaedic bone cutting processes such as osteotomy and hip arthroplasty involve the cutting of one with the aid of various manual and powered cutting instruments including manual and powered bone saws. The extent of surgically induced bone necrosis at the point of the cutting tool and the bone is mainly due to the frictional heat generated by bone cutting. Bone necrosis has an impact on bone regeneration, and the rate of healing of the bone post operation. The threshold temperature for impaired regeneration of bone is in the range of 44°C to 47°C. Overheating also affects the sharpness life of …

Detection Of Microcracks During Bone Cutting Using Acoustic Emission Techniques, Ashkan Safari, Ger Reilly, Brendan Mccormack

Conference Papers

Surgeons may use a number of cutting instruments such as osteotomes and chisels to cut bone during operative procedures. The initial loading of cortical bone during the cutting process results in the formation of microcracks in the vicinity of the cutting zone with main crack propagation to failure occurring with continued loading; microcracking acts as a stimulus for main crack formation and has also been shown to occur during the propagation of the main crack. It has also been reported that Acoustic Emission (AE) is generated due to microcrack formation and crack growth, prior to, and during final fracture in …

Wright State University College Of Engineering And Computer Science Bits And Pcs Newsletter, Volume 22, Number 1, September 2005, College Of Engineering And Computer Science, Wright State University

BITs and PCs Newsletter

A ten page newsletter created by the Wright State University College of Engineering and Computer Science that addresses the current affairs of the college.

The Human Eye Position Control System In A Rehabilitation Setting, Yvonne Nolan, Ted Burke, C. Boylan, Annraoi De Paor

Articles

Our work at Ireland’s National Rehabilitation Hospital involves designing communication systems for people suffering from profound physical disabilities. One such system uses the electro-oculogram, which is an (x,y) system of voltages picked up by pairs of electrodes placed, respectively, above and below and on either side of the eyes. The eyeball has a dc polarisation between cornea and back, arising from the photoreceptor rods and cones in the retina. As the eye rotates, the varying voltages projected onto the electrodes drive a cursor over a mimic keyboard on a computer screen. Symbols are selected with a switching action derived, for …

Lextran Support Project: Strategic Planning Support For Lextran Visioning, Lenahan O'Connell, Ted Grossardt

Kentucky Transportation Center Research Report

In October 2003, LexTran, the City of Lexington’s public transportation provider, was undergoing a management transition. It sought the assistance of the Kentucky Transportation Center for strategic planning and visioning. This project produced four deliverables: (1) a series of public meetings facilitated by the Kentucky Transportation Center on rider and other stakeholder attitudes toward LexTran and its general performance; (2) an environmental scan comparing LexTran to similar transit providers on operating efficiency, ridership, funding sources, and other characteristics; (3) A GIS database containing census data and other information useable for the analysis of proposed routes; and (4) a PowerPoint presentation …

Laser And Led Effects On The Proliferation Rate Of Periodontal Ligament Fibroblasts, Allen J. Job

Loma Linda University Electronic Theses, Dissertations & Projects

PURPOSE: To compare the effectiveness of a Gallium Aluminum Arsenide (GaAlAs) diode laser and a light emitting diode (LED) on periodontal ligament fibroblast cell proliferative rates.

METHODS and MATERIALS: PDLF obtained from freshly extracted permanent teeth were cultured under standard conditions until a subconfluent monolayer was present. The next section took 5 days to complete. On day 1, the initial cell concentration of 700 uL/cm² was plated on 96-well assay plates and placed in a CO₂ incubator at 37° C for 24 hours. On day 2, cell counts were first verified using hemocytometry then were irradiated using an …

Bs News

Building Services Engineering

No abstract provided.

Operator State Estimation For Adaptive Aiding In Uninhabited Combat Air Vehicles, Christopher A. Russell

Theses and Dissertations

This research demonstrated the first closed-loop implementation of adaptive automation using operator functional state in an operationally relevant environment. In the Uninhabited Combat Air Vehicle (UCAV) environment, operators can become cognitively overloaded and their performance may decrease during mission critical events. This research demonstrates an unprecedented closed-loop system, one that adaptively aids UCAV operators based on their cognitive functional state A series of experiments were conducted to 1) determine the best classifiers for estimating operator functional state, 2) determine if physiological measures can be used to develop multiple cognitive models based on information processing demands and task type, 3) determine …

Contrast-Detail Analysis Characterizing Diffuse Optical Fluorescence Tomography Image Reconstruction, Scott C. Davis, Brian W. Pogue, Hamid Dehghani, Keith D. Paulsen

Dartmouth Scholarship

Contrast-detail analysis is used to evaluate the imaging performance of diffuse optical fluorescence tomography (DOFT), characterizing spatial resolution limits, signal-to-noise limits, and the trade-off between object contrast and size. Reconstructed images of fluorescence yield from simulated noisy data were used to determine the contrast-to-noise ratio (CNR). A threshold of CNR=3 was used to approximate a lowest acceptable noise level in the image, as a surrogate measure for human detection of objects. For objects 0.5 cm inside the edge of a simulated tissue region, the smallest diameter that met this criteria was approximately 1.7 mm, regardless of contrast level, and test …

Multifractal Analysis Of Heart Rate Variability Using Wavelet-Transform Modulus-Maxima Method, Chirag Jani

Theses

Physiological signals are complex and carry information of human health. Recent studies reveal that under normal conditions, the heart rate time series shows multifractal behavior. In contrast, HRV in the pathological state such as congestive heart failure exhibits more monofractal-like structure. Recent advances in the assessment of heart rate variability (HRV) uses a nonlinear dynamics approach. In this study, the main objective is to use the wavelet-transform modulus-maxima method for the multifractal analysis of the heart rate time senes.

The degree of the multifractality is defined by the singularities (a point in time series where a mathematical function is not …

Quantification Of Long-Range Power Law Correlations Among Healthy And Pathologic Subjects Using Detrended Fluctuation Analysis And Multifractal Detrended Fluctuation Analysis, Hardick Raval

Theses

The healthy heartbeat is traditionally thought to be regulated according to the classical principle of homeostasis whereby physiologic systems operate to reduce variability and achieve an equilibrium-like state. However recent studies reveal that under normal conditions, beat-to-beat fluctuation in heart rate display the kind of long-range correlations typically exhibited by the dynamical system far away from equilibrium. In contrast, heart rate time series from patients with severe congestive heart failure show a breakdown of this long-range correlation behavior. Two different non-linear dynamic methods namely Detrended Fluctuation Analysis (DFA) and Multifractal (MF) DFA are used for the quantification of this correlation …

The Creation And Testing Of A Mock Functional Magnetic Resonance Imaging Facility For Pain Patients, Gladstone Vincent Reid

Theses

Unfamiliarity with functional Magnetic Resonance Imaging (fMRI) facilities leads to unwanted stress-related disturbances in the processing of fMRI data. A mock fMRI facility was developed to increase familiarization among subjects participating in fiviRI studies and to alleviate the time and cost of familiarizing each subject in an actual fMRI facility. A decommissioned Magnetic Resonance Imaging (MRI) unit was remodeled to visually and aurally resemble the Siemens Magnetom Allegra 3 Telsa fMRI machine currently used at the University of Medicine and Dentistry of New Jersey (UMDNJ), Newark, New Jersey. Instrumentation was developed using LabVIEW software which presented subjects with recreated sounds …

Quantification Of Regularity In Rr-Interval Time Series Using Approximate Entropy, Sample Entropy, And Multi-Scale Entropy, Nirvish Shah

Theses

Heart rate variability (HRV) has proven to be a useful noninvasive tool to study the neuronal control of the heart. Recently, nonlinear dynamic methods based on chaos theory and fractal dynamics have been developed to uncover the nonlinear fluctuations in heart rate. Approximate Entropy (ApEn), Sample Entropy (SampEn) and Multi-scale Entropy (MSE) are measures based on chaos theory that quantify the regularity in time series. This study has been designed to examine the ability of these measures to distinguish the RR-interval time series of normal subjects (NSR) from subjects with congestive heart failure (CHF). The study was conducted on the …

Combined Effects Of Prozac And Hypothalmic Mediated Response On Masseter Muscle Activity In The Cat, Chika P. Nwaorgu

Theses

The present study tested the hypothesis that infusion of Prozac would serve to suppress defensive rage elicited from the medial hypothalamus of the cat. Cats are known to exhibit certain kind of behavior, known as the "defensive rage response" such as unsheathing of the claws, retraction of the ear and vocalization (hissing).

Three adult cats (2 males and 1 female) weighing (2.8 - 3.4 kg) were utilized during the experiments. Cannula-electrodes were implanted into the medial hypothalamus for elicitation of defensive rage behavior. EMG activity was recorded with a bipolar electrode attached to the masseter muscle to establish baseline before …

Automated Liquid Dispensing Pin For Dna Microarray Applications, Suganya Parthasarathy

Theses

This thesis describes the research and development of a new liquid dispensing/aspiring system that is capable of producing micro sized spots/droplets for molecular biology research and analysis. In particular, the application is focused on DNA microarray fabrication with the goals of smaller spot size, higher yield, more efficient usage of biological materials, and capability to handle high viscosity liquids. The new system is based on active sensing and control and it is part of a fully integrated robotic microarray system for genomic and proteomic applications. The prototype system handles water as well as thick liquids such as 100% glycerol and …

Keynote: Research And Education In Telecommunication Engineering, Akhtar Kalam

International Conference on Information and Communication Technologies

Telecommunications over the past one hundred years has had a major influence on the development of society. Telecommunications will continue to play an increasingly important role in nearly every human endeavour in all nations of the earth. Telecommunication industry is currently facing a technological revolution. In many countries, the number of cellular radio subscribers exceeds the subscribers of fixed telephony services. Internet technologies, such as VoIP and SIP, allow the convergence of traditional switched telephony services and data services of the internet to converge. New wireless access technologies compete and complete the services provided by the modern cellular radio networks. …

Stormwater Intelligent Control System (2005), Martin Wanielista

BMP Trains Research and Publications

Water restrictions, pollution control, volume balances, and the emergence of stormwater utilities have lead to the development of an automated intelligent system (“I-Water”) for water use and control. With the use of this system, water stored in stormwater ponds or in the surficial aquifer is not discharged to surface waters because it is used to meet water demands, such as, lawn irrigation, environmental protection, agriculture, drinking and industrial uses.

The drop in groundwater levels and the increasing use of reclaimed water illustrates a need for alternative water supplies. Ground water depletion is occurring which is adding to the destruction of …

Biodiesel Plant Development Seminar, Larry Breeding

Industrial Agricultural Products Center: Publications and Information

CONTENTS:
West Central History
Annual Operations
Sales History (millions)
Soy Nutrition Products
West Central Biodiesel Plant
Why Biodiesel?
Reduce Emissions
Operational Benefits
Energy Balance of Biodiesel
Expanded use for Soy Crops
Nation’s Energy Goals
USES FOR BIODIESEL
RENEWABLE ENERGY GROUP
MANAGEMENT
PROCUREMENT
SALES & MARKETING
SUMMARY

Biodiesel Plant Investment—Making The Correct Decisions, Leland Tong, Steve Howell

Industrial Agricultural Products Center: Publications and Information

Overall Purpose of IBFG:
• Provide the most accurate, up-to-date, detailed, independent information on biodiesel and the biodiesel industry
• Provide Information you need to make an intelligent decision on a biodiesel plant….

Purification And Scale-Up Of A Recombinant Heavy Chain Fragment C Of Botulinum Neurotoxin Serotype E In Pichia Pastoris Gs115, Michael P. Dux, Rick Barent, Jayanta Sinha, Mark Gouthro, Todd Swanson, Ardis Barthuli, Mehmet İnan, John T. Ross, Leonard A. Smith, Theresa J. Smith, Robert Webb, Bonnie Loveless, Ian Henderson, Michael M. Meagher

Papers in Biochemical Engineering

A recombinant C-terminus heavy chain fragment from Botulinum neurotoxin serotype E (BoNT/E) is proposed as a vaccine against the serotype E neurotoxin. This fragment, rBoNTE(Hc), was produced intracellular in Pichia pastoris GS115 by a three-step fermentation process, i.e., glycerol batch phase and a glycerol fed-batch phase to achieve high cell densities, followed by a methanol fed-batch induction phase. The rBoNTE(Hc) protein was purified from the soluble fraction of cell lysates using three ion-exchange chromatography steps (SP Sepharose Fast Flow, Q Sepharose Fast Flow, Sp Sepharose High Performance) and polished with a hydrophobic charge induction chromatography step (MEP HyperCel). Method development …

Disasters: Photovoltaics For Special Needs, Florida Solar Energy Center, William Young

FSEC Energy Research Center®

The National Hurricane Center tracks the path of a hurricane to determine where it will make landfall. People in harm's way are informed of its approach and the need to evaluate options to prevent injury and protect lives. One of the many groups of people at high risk is those with special needs. They have health conditions that require special care. Before a disaster, these individuals live in hospitals, care facilities and homes. During and following a disaster, many would be moved, along with their supplies, equipment and a caretaker, to a special needs shelter. Others would stay with relatives …

Renewable Energy And Disaster-Resistant Buildings, Florida Solar Energy Center, William Young

FSEC Energy Research Center®

Hurricanes, floods, tornados and earthquakes create natural disasters that can destroy homes, businesses and the natural environment. Such disasters can happen with little or no warning, leaving hundreds or even thousands of people without medical services, potable water, sanitation, communications and electrical services for up to several weeks. The 2004 hurricane season ravaged the State of Florida, U.S.A., with four major hurricanes within a 6-week timeframe. Over nine million people evacuated their homes and damage to property was extensive.

One proactive strategy to minimize this type of destruction and disruption to lives is the implementation of disaster-resistant buildings that are …

A Chain-Type Wireless Sensor Network For Monitoring Long Range Infrastructures, Chang Wen Chen, Yu Wang, Ivica Kostanic

Electrical Engineering and Computer Science Faculty Publications

We present in this paper an investigation on a special class of wireless sensor networks for monitoring critical infrastructures that may extend for hundreds of miles in distances. Such networks are fundamentally different from traditional sensor networks in that the sensor nodes in this class of networks are deployed along narrowly elongated geographical areas and form a chain-type topology. Based on careful analysis of existing sensor network architectures, we first demonstrate the needs to develop new architecture and networking protocols to match the unique topology of chain-type sensor networks. We then propose hierarchical network architecture that consists of clusters of …

Novel Distributed Cable Sensors For Detection Of Cracks In Rc Structures, Genda Chen, David Pommerenke

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

In this paper, the development of a fundamentally new, topology-based cable sensor design concept is summarized for crack detection in reinforced concrete (RC) structures. The sensitivity, spatial resolution, and signal loss of sensors are investigated both numerically and experimentally. Two sensors were fabricated and validated with small- and large-scale laboratory tests under different loads. Both were proven sensitive to crack of various sizes from visually undetectable to excessive, giving the location and severity of damage simultaneously. One sensor has been installed on a three-span bridge for its long-term monitoring. It is capable of recording damage that has occurred during a …

Evolutionary Algorithm For The Placement Of Fluid Power Valves On A Valve Stand, Trichy M. Kethara Pasupathy, Ravi Teja Seethamraju, Robert G. Wilhelm

Department of Mechanical and Materials Engineering: Faculty Publications

The choice of placement of fluid power valves on a valve stand and routing by pipes has an impact on operational costs. Choosing the right placement that provides optimum routing configuration or determining the optimum routing for a chosen placement are both computationally hard problems. An evolutionary algorithm (EA), to minimize operational costs while optimizing placement and routing of valves, is developed here. The best practices in the industry are abstracted and implemented in the EA. In this paper, the algorithm and its performance for examples with varying complexities are presented. Our results meet or exceed experienced designers’ solutions.