Digital Commons Network^™

Fate And Transport Of Escherichia Coli Within Sediment Basins On Active Construction Sites, Elizabeth Tempel

All Theses

The conventional method of controlling sediment-laden runoff on construction sites is the use of sediment basins. These basins slow the velocity of runoff and allow the particles to settle from the water column before discharge to surface waters offsite. This best management practice, however, may create a reservoir for pathogenic bacteria. Sediment is known to provide protection for bacteria; therefore, while these basins decrease sediment loadings to water bodies downstream, they may introduce harmful levels of pathogenic bacteria into these surface waters. In addition to causing human health risks, these high bacteria levels alter natural biological makeup of downstream ecosystems. …

A Quantitative, Technology Independent, Fidelity Metric For Evaluating Bioprinted Patterned Co-Cultures, Matthew Pepper

All Theses

The study of cell-cell interactions is crucial in the understanding of cell behaviors such as tumor genesis, proliferation, migration, metastasis, and apoptosis. To break down the complex web of signals in vivo, researchers must replicate some parts of this environment with in vitro tissue test systems, composed of multiple cell types arranged close enough to communicate with their neighbors, i.e. high-resolution co-culture patterns. The field of bioprinting is specifically focused on creating co-culture patterns for the purposes of cell studies, but the sample resolutions of most bioprinting systems are still too coarse to permit cell communication. No way currently exists …

Effects Of Microenvironment On Growth And Differentiation Of Human Dental Pulp Cells, Laura Datko

All Theses

Dental pulp stem cells (DPSCs) have recently been described as a potential stem cell source for various regenerative medicine and tissue engineering applications. They appear to be multipotent, however more characterization is necessary to determine the true potential of these cells. An important aspect of using DPSCs, or any stem cell type, tissue engineering application is the microenvironment within the construct. The microenvironment could include construct mechanical properties, construct composition, and 3D dynamic conditions in vivo. This work aims to study those specific microenvironment effects on DPSCs. To determine the effects of mechanical properties of the substrate on DPSCs, they …

Influence Of Material Selection And Fabrication Process Repeatability On Mechanical Properties Of Glass-Polymer Matrix Composite Structures, Charles Edwards

All Theses

This study has aimed to evaluate property uniformity from data obtained utilizing one design of a single layup composite plaque, three sources of glass fibers and a single, industry accepted resin to produce a repeatable fabrication process. This thesis has investigated the following:
1. Whether the type of glass (E-Glass, S-Glass, and R-Glass) influences the property values of individually tested samples compared between glass types.
2. Whether the type of glass influences the property uniformity throughout the set of tested samples.
3. Whether the composite plaque design and resulting performance, as defined by ASTM Standards or industry accepted parameters, is …

Strengthening The Anonymity Of Anonymous Communication Systems, Christopher Abbott

All Theses

In this work, we examine why a popular anonymity network, Tor, is vulnerable to timing side-channel attacks. We explore removing this vulnerability from Tor without sacrificing its low-latency which is important for usability.
We find that Tor is vulnerable because inter-packet delays propagate along the network path from the source to the destination. This provides an easily detected signature. We explore techniques for making the timing signature either expensive or impossible to detect.
If each packet took a unique, disjoint path from source to destination the inter-packet delay signature would be undetectable. Jitter and latency would change packet arrival orders. …

Salen Mn Complexes Mitigate Radiation Injury In Normal Tissues, Rosalind A. Rosenthal, Brian Fish, Richard P. Hill, Karl D. Huffman, Zelmira Lazarova, Javed Mahmood, Meetha Medhora, Robert C. Molthen, John E. Moulder, Stephen T. Sonis, Philip J. Tofilon, Susan R. Doctrow

Biomedical Engineering Faculty Research and Publications

Salen Mn complexes, including EUK-134, EUK-189 and a newer cyclized analog EUK-207, are synthetic SOD/catalase mimetics that have beneficial effects in many models of oxidative stress. As oxidative stress is implicated in some forms of delayed radiation injury, we are investigating whether these compounds can mitigate injury to normal tissues caused by ionizing radiation. This review describes some of this research, focusing on several tissues of therapeutic interest, namely kidney, lung, skin, and oral mucosa. These studies have demonstrated suppression of delayed radiation injury in animals treated with EUK-189 and/or EUK-207. While an antioxidant mechanism of action is postulated, it …

The Measurement Of Bone Quality In Medical Images Using Statistical Textural Features, Ning Huang

Electrical Engineering Theses

Mineral density and bone architecture properties are the main measures of bone quality. Dual-energy X-ray Absorptiometry (DXA) is the traditional clinical measurement technique for bone mineral density, but it is insensitive to architectural information. Image analysis of the architectural properties of bones can be used to predict bone quality. This study is aimed at investigating the statistical parameters extracted from wo dimensional projection images of the DXA scans and exploring its link with architectural properties, and its correlation with a bones mechanical properties. In this research, features extracted from the Gray Level Co-occurrence Matrix (GLCM) for a 2D image are …

Elliptical Machine Dc-Dc Converter For The Energy Harvesting From Exercise Machines Project, Greg Hollister

Electrical Engineering

Designing a DC/DC Converter for the Cal Poly Energy Harvesting from Exercise Machines project requires special attention to the unique operating characteristics of the source and the load. An elliptical machine powered by a person exercising comprises the source, while an AC Inverter makes up the load. This project attempts to integrate the two devices with a custom DC/DC Converter in order to ultimately deliver power back into the power grid.

A Relativistic Enhancement To Software Transactional Memory, Philip William Howard, Jonathan Walpole

Computer Science Faculty Publications and Presentations

Relativistic Programming is a technique that allows low overhead, linearly-scalable concurrent reads. It also allows joint access parallelism between readers and a writer. Unfortunately, it has so far been limited to a single writer so it does not scale on the write side. Software Transactional Memory (STM) is a technique that allows programs to take advantage of disjoint access parallelism on both the read-side and write-side. Unfortunately, STM systems have a higher overhead than many other synchronization mechanisms so although STM scales, STM starts from a lower baseline. We propose combining relativistic programming and software transactional memory in a way …

Modification Of Pathways With Pseudomonas For The Extraction And Subsequent Conversion Of Algae To Butanol, Danielle Frechette

Biological and Agricultural Engineering Undergraduate Honors Theses

As the demand for alternative fuels steadily increases, algae continue to be an excellent source for the development of biofuels. While algae have exhibited substantial potential for butanol production, there are limitations when it comes to the extraction process-its inability to withdraw oils and sugars usable for fermentation from cell walls. The genes of two bacteria were combined, creating a new organism that can both extract sugars and oils from algal cell walls and create butanol, simplifying the fermentation process while increasing efficiency. Pseudomonas flourescens, an obligate aerobe, has been shown in literature to degrade these cell walls to make …

Monitoring Civil Infrastructure Using Image Template Matching, Vikram Mukesh Patel

Boise State University Theses and Dissertations

Structural health monitoring (SHM) is an active area of research devoted to systems that can autonomously and proactively assess the structural integrity of civil structures. This thesis explores the possibility of monitoring civil structures using image template matching and low-cost embedded data acquisition. By acquiring several consecutive images of a structure, one can determine if movement in the structure has occurred. This information can be analyzed to determine long-term changes within a structure, which can then be used to proactively prioritize maintenance, reduce maintenance costs, and prevent structural failure. This will allow structures to be maintained based on objective data …

Cost Efficient Method Of Pumping Water For Small, Remote Rural Communities, James Hudson

Chemical Engineering Undergraduate Honors Theses

Many technologies are used for water disinfection. Chlorine, iodine, and ozone are some chemical methods of water disinfection. Filtration, including microfiltration, ultrafiltration, and reverse osmosis, is used to remove bacteria. In addition to chemical and filtration technologies, one can disinfect water using UV irradiation, ultrasonic treatment, electrolysis, solar disinfection, and slow sand filtration.
Currently, there are few solutions being employed in third world settings for communities. The current solutions are either for one household or are part of an existing infrastructure and therefore are not portable. Slow sand filtration is used successfully to provide potable water for individual households. Tablet …

Application Of Nanotechnology For Targeted Delivery Of Antibacterial Enzymes And For Enzyme-Based Coatings On Medical Devices And Implants, Rohan Satishkumar

All Dissertations

The frequency of S. aureus infection and subsequent biofilm formation associated with vascular catheterization has been increasing in recent years and often begins as a local colonization at the site of the catheter insertion. Antimicrobial enzymes and peptides, which are effective against a broad range of pathogens and low rates of resistance, have attracted attention as promising alternative candidates in treatment of infections caused by antibiotic resistant bacteria. The use of nanoparticles as carriers for enzymes, in addition to their size, charge, high surface area per volume etc. offers targeted delivery of enzymes to pathogenic bacteria. We proposed to use …

Energy Harvesting From Elliptical Machines Using Four-Switch Buck-Boost Topology, Alvin Jay Hilario

Master's Theses

This thesis presents the topic of using the Four-Switch Buck-Boost topology as a DC-DC converter for the Energy Harvesting from Elliptical Machines Project. The project works toward providing a modular synchronous power generation system. Due to the dynamic and sporadic output voltage and power characteristics of the Precor elliptical machine, the system requires a DC-DC converter as a voltage preregulator. The inherent wide input range, high efficiency, and low parts cost of this converter well suit the application. This paper further discusses other topologies and their shortcomings, as well as characterizes the Precor elliptical machine and Enphase Microinverter for interfacing. …

A Wireless Sensor Network For Monitoring Physical Activity, Physiological Response, And Environmental Conditions, Michael Leon Pook

Boise State University Theses and Dissertations

Understanding movement is an important area of research for improving comfort and safety. Data collected from accelerometers and gyros attached to multiple parts of a body can be used to determine the type of physical activity in which an individual is engaging. Correlating this data with the individual's heart rate allows for the verification of the type of activity as well as observation of the amount of physical strain experienced during the activity. Additionally, data on environmental stimuli can be gathered in order to determine their effect on physical strain. Current research in the field has been limited by both …

Characterization Of Potential Health Promoting Lipids In The Co-Products Of De-Flossed Milkweed, Vicki Schlegel, Richard Zbasnik, Tammy Gries, Bo Hyun Lee, Timothy Carr, Ji-Young Lee, Curtis Weller, Susan Cuppett

Department of Agricultural and Biological Systems Engineering: Faculty Publications

The floss and oil of the common milkweed (Asclepias syriaca L.) seeds are currently used to produce comforters/pillows and skin care products, respectively. As an outcome of these products, copious quantities co-products (pressed seed meal and pod biomass) are disposed of each year despite the presence of potential health benefiting lipids. The objective of this project was to determine the feasibility of developing the lipid fraction from of these co-products for the fast growing dietary human health market. Although certain types of lipids were affected by the extraction solvent used (hexane and diethyl ether) as were overall amounts, analysis …

Clean Energy Water Disinfection International Environmental Education Design Contest, Howard Heffington

Chemical Engineering Undergraduate Honors Theses

Many technologies are used for water disinfection. Chlorine, iodine, and ozone are some chemical methods of water disinfection. Filtration, including microfiltration, ultrafiltration, and reverse osmosis, is used to remove bacteria. In addition to chemical and filtration technologies, one can disinfect water using UV irradiation, ultrasonic treatment, electrolysis, solar disinfection, and slow sand filtration.
Currently, there are few solutions being employed in third world settings for communities. The current solutions are either for one household or are part of an existing infrastructure and therefore are not portable. Slow sand filtration is used successfully to provide potable water for individual households. Tablet …

Water Purification For Rural Communities Using Ultraviolet Light And Bleach Systems, Ryan Lee

Chemical Engineering Undergraduate Honors Theses

Many technologies are used for water disinfection. Chlorine, iodine, and ozone are some chemical methods of water disinfection. Filtration, including microfiltration, ultrafiltration, and reverse osmosis, is used to remove bacteria. In addition to chemical and filtration technologies, one can disinfect water using UV irradiation, ultrasonic treatment, electrolysis, solar disinfection, and slow sand filtration.
Currently, there are few solutions being employed in third world settings for communities. The current solutions are either for one household or are part of an existing infrastructure and therefore are not portable. Slow sand filtration is used successfully to provide potable water for individual households. Tablet …

Non-Natural Protein Mimetics For The Treatment Of Alzheimer's Disease, Jennifer Herrera, Amanada Compean, Jasmine Brown, Melissa Moss, Shannon Servoss

Chemical Engineering Undergraduate Honors Theses

Alzheimer's disease (AD) is a slow degenerative disease that causes memory loss and eventually leads to death. AD is caused by the aggregation of the amyloid-beta protein, found on the outside of brain cells; once the amyloid-beta protein begins to aggregate it forms plaques on the extracellular part of the neural cells. To date there is no AD medication commercially available that breaks up the amyloid-beta aggregates. Current research has found that certain molecules bind to the amyloid-beta protein and prevent aggregation. The purpose of this research project is to engineer a peptoid-based molecule to stop the aggregation of the …

Measuring The Removal Of Trichloroethylene From Phytoremediation Sites At Travis And Fairchild Air Force Bases, Heather A. Klein

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Past use of trichloroethylene (TCE) as a degreasing solvent for aircraft maintenance has resulted in widespread groundwater contamination at Air Force Bases around the world. Travis AFB in California and Fairchild AFB in Washington are evaluating phytoremediation as a treatment option, since trees have been reported to take up dissolved TCE from shallow groundwater and volatilize it to the atmosphere while enhancing the volatilization of TCE from surrounding soil. Previous studies generally focused on the identification of removal mechanisms. The emphasis of this research was to quantify total TCE removal from phytoremediation demonstration plots at Travis and Fairchild AFBs.

Tree …

A Study On The Applications And Toxicity Assessments Of Carbon Nanotubes In Tissue Engineering, Rena Baktur

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Carbon nanotubes (CNTs) are one of the most popular nanomaterials. There has been increasing interest in the development and applications of carbon nanotubes due to their huge potential in industrial and medical applications. Recent applications of carbon nanotubes include development of scaffolds and drug delivery systems. Despite rapidly emerging applications of CNTs, little is known about the impact of CNTs on cellular processes, especially mesenchymal stem cell (MSC)'s differentiation. Also, the effects of nanoparticle exposure under different conditions on cellular responses have not been well characterized yet.

To characterize the effects of CNTs on creating nanoscale scaffolds for tissue engineering, …

Perching Using A Quadrotor With Onboard Sensing, Jeremy C. Goldin

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

This thesis presents an implementation of autonomous indoor perching using only onboard sensors on a low-cost, custom-built quadrotor. The perching aggressive maneuver is representative of a class of control problems for aerobatics that requires an agile and robust control system for maneuvering accurately at high speeds. Such research extends the typical functionality of micro air vehicles (MAV) from low speed and stationary observation to dynamic aerobatic transitions for broader operational capabilities including confined landings and evasive maneuvering. To achieve this, three major challenges are overcome: precise and real-time positioning, sensing of the perch and path to the perch, and control …

Performance Of Transverse Post-Tensioned Joints Subjected To Negative Bending And Shear Stresses On Full Scale, Full Depth, Precast Concrete Bridge Deck System, Kayde Steven Roberts

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Accelerated bridge construction has quickly become the preferred method for the Utah Department of Transportation (UDOT) as well as many other DOT’s across the United States. This type of construction requires the use of full depth precast panels for the construction of the bridge deck. The segmented deck panels produce transverse joints between panels and have come to be known as the weakest portion of the deck. Cracking often occurs at these joints and is reflected through the deck overlay where water accesses and begins corrosion of the reinforcement and superstructure below. For this reason post-tensioning of the deck panels …

Clustering Educational Digital Library Usage Data: Comparisons Of Latent Class Analysis And K-Means Algorithms, Beijie Xu

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

There are common pitfalls and neglected areas when using clustering approaches to solve educational problems. A clustering algorithm is often used without the choice being justified. Few comparisons between a selected algorithm and a competing algorithm are presented, and results are presented without validation. Lastly, few studies fully utilize data provided in an educational environment to evaluate their findings. In response to these problems, this thesis describes a rigorous study comparing two clustering algorithms in the context of an educational digital library service, called the Instructional Architect.

First, a detailed description of the chosen clustering algorithm, namely, latent class analysis …

Algal Biofilm Production And Harvesting System For Wastewater Treatment With Biofuels By-Products, Logan Christenson

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Excess nitrogen and phosphorus in discharged wastewaters can lead to downstream eutrophication, ecosystem damage, and impaired water quality that may affect human health. Chemical-based and physical-based technologies are available to remove these nutrients; however, they often consume significant amounts of energy and chemicals, greatly increasing treatment costs. Algae are capable of removing these pollutants through biomass assimilation, and if harvested, can be utilized as a feedstock for biomethane or biodiesel production. Currently, difficulties in harvesting, concentrating, and dewatering algae have limited the development of an economically feasible treatment and production process. When algae are grown as surface-attached biofilms, the biomass …

Modelling And Hazard Analysis For Contaminated Sediments Using Stamp Model, Karim Hardy, Franck Guarnieri

Publications

Processes for remediation (removal of pollution or contaminants) of contaminated sediments have become very efficient. These technologies, which are particularly complex, call for a comprehensive approach to risk analysis which characterises all threats (to humans, equipment, local residents, the environment etc.). The STAMP accident model (Systems-Theoretic Accident Model and Processes) is an example of such a comprehensive approach, and it has been chosen to characterise the risks associated with Novosol®, an innovative remediation process. Risk analysis is carried out through the application of STPA (STamP-based Analysis). This article is organised into three sections. The first describes the Novosol® process for …

Evaluation Of Delivery Conditions For Cutaneous Plasmid Electrotransfer Using A Multielectrode Array, Bernadette Ferraro, Loree C. Heller, Yolmari L. Cruz, Siqi Guo, Amy Donate, Richard Heller

Bioelectrics Publications

Electroporation (EP) is a simple in vivo method to deliver normally impermeable molecules, such as plasmid DNA, to a variety of tissues. Delivery of plasmid DNA by EP to a large surface area is not practical because the distance between the electrode pairs, and therefore the applied voltage, must be increased to effectively permeabilize the cell membrane. The design of the multielectrode array (MEA) incorporates multiple electrode pairs at a fixed distance to allow for delivery of plasmid DNA to the skin, potentially reducing the sensation associated with in vivo EP. In this report, we evaluate the effects of field …

An Empirical Comparison Of Life Cycle Cost Of Green School Buildings And Non-Green School Buildings, Nitisha Pushpala

UNLV Theses, Dissertations, Professional Papers, and Capstones

One of the major economic concerns today of the world is reduction of energy consumption because of depleting energy sources in the world. The construction sector in the United States is also contributing in reducing the energy consumption and construction cost of the buildings by constructing cost and energy efficient buildings with energy efficient materials and techniques. The U.S Department of Energy introduced the Building Technologies Program that develops techniques, tools and technologies for making buildings more energy efficient. Other private bodies like the Leadership in Energy and Environmental Design (LEED), which is developed by the U.S. Green Building Council …

Association Of Oceanic-Atmospheric Oscillations And Hydroclimatic Variables In The Colorado River Basin, Ajay Kalra

UNLV Theses, Dissertations, Professional Papers, and Capstones

With increasing evidence of climatic variability, there is a need to improve forecast for hydroclimatic variables i.e., precipitation and streamflow preserving their spatial and temporal variability. Climatologists have identified different oceanic-atmospheric oscillations that seem to influence the behavior of these variables and in turn can be used to extend the forecast lead time. In the absence of a good physical understanding of the linkages between oceanic-atmospheric oscillations and hydrological processes, it is difficult to construct a physical model. An attractive alternative to physically based models are the Artificial Intelligence (AI) type models, also referred to as machine learning or data-driven …

Comparative Fecal Metagenomics Unveils Unique Functional Capacity Of The Swine Gut, Regina Lamendella, Jorge W. Santo Domingo, Shreya Ghosh, John Martinson, Daniel B. Oerther

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

Background: Uncovering the taxonomic composition and functional capacity within the swine gut microbial consortia is of great importance to animal physiology and health as well as to food and water safety due to the presence of human pathogens in pig feces. Nonetheless, limited information on the functional diversity of the swine gut microbiome is available. Results: Analysis of 637, 722 pyrosequencing reads (130 megabases) generated from Yorkshire pig fecal DNA extracts was performed to help better understand the microbial diversity and largely unknown functional capacity of the swine gut microbiome. Swine fecal metagenomic sequences were annotated using both MG-RAST and …