Digital Commons Network^™

Smart Dressings Accelerating Wound Healing With Tranexamic Acid-Infused Aligned Electrospun Nanofibers: In Vitro And In Vivo Assessments, Samar A. Salim, Abdullah Elbadry, Eman Gomaa, Mennatullah Faisal, Elbadawy A. Kamoun

Nanotechnology Research Centre

The development of advanced wound dressings capable of accelerating healing and achieving effective hemostasis remains a critical challenge in managing traumatic and surgical wounds. This study reports the fabrication and comprehensive evaluation of a novel multilayered, sandwich-structured nanofiber scaffold composed of Tranexamic acid (TXA), chitosan (CS), polyvinyl alcohol (PVA), L-arginine, and polylactic acid (PLA) for biodegradable wound dressing applications. Using sequential electrospinning, a four-layered scaffold was developed as a smart wound dressing, comprising an immediate-release TXA-CS-PVA layer for rapid clotting, a hydrophobic PLA barrier layer for protection, a sustained-release L-arginine-PVA layer to promote tissue regeneration, and a final PLA protective …

Internet Of Batteries: An Integrated System Of Battery Health Surveillance System For Electric Vehicles (Evs), Ayodeji Akinsoji Okubanjo, Ignatius Kema Okakwu, Alexander Akpofure Okandeji, Oluwasogo Emmanuel Seun, Olusesi Ayobami Taiwo

AUIQ Technical Engineering Science

Progress in storage technologies is vital to the efficiency of electric vehicles in combating climate change. The automobile industry’s transition to electric mobility has significantly increased the demand for battery storage systems (BSS) in terms of performance, reliability, monitoring, and evaluation of key parameters. However, poor safety and monitoring strategies for battery storage systems in electric vehicle applications pose an increasing threat to the vehicles’ sustainability and mobility. This calls for intelligent battery storage monitoring systems to mitigate carbon footprint and preserve battery lifespan of electric vehicles. This paper focuses on battery storage sustainability in electric vehicles with special emphasis …

Effect Of Gelam Wood And Rice Husk Composition With Molding Pressure On The Combustion Performance Of Biopellets, Rachmat Subagyo, Rudi Siswanto, Ma’Ruf Ma’Ruf, Mastiadi Tamjidillah, Abdul Ghofur, Femiana Gapsari, M. Zainul Rusdi, Azie Aprianto, Wardoyo Wardoyo, Naila Salsabila

Journal of Mechanical Engineering Science and Technology (JMEST)

This study investigates the effects of gelam wood (Melaleuca leucadendron) and rice husk composition in biopellet production, focusing on compaction pressures of 60, 80, and 100 kg/cm². Five biomass ratios (G100–RH0, G80–RH20, G60–RH40, G50–RH50, G0–RH100) were tested for moisture, ash, fixed carbon, volatile matter, calorific value, ignition time, burning rate, and combustion temperature. Results showed that moisture content ranged from 0.98% (G0–RH100, 60 kg/cm²) to 12.28% (G100–RH0, 80 kg/cm²), while ash content varied between 2.47% (G100–RH0, 60 kg/cm²) and 20.93% (G0–RH100, 80 kg/cm²). The highest calorific value reached 3968 cal/g (G100–RH0, 60–80 kg/cm²), though below the SNI 8675:2018 minimum of …

Novel Biomolecule-Infused Gelatin Injectable For Treatment Of Recurrent Laryngeal Nerve Injury, Ananya Tadikonda, Sunjay Anekal, Lena W. Chen, Gabriel Sobczak, Troy Wesson, Carmilya Jackson, Marisa A. Egan, Julie C. Liu, Patrick R. Finnegan, Stacey Halum

School of Chemical Engineering Faculty Publications

Objective

Unilateral vocal fold paralysis (UVFP) due to recurrent laryngeal nerve injury (RLN) is a major cause of voice disorders. We have recently identified three biomolecules (agrin, acetylcholine, and neuregulin) with the potential to promote reinnervation after RLN injury. This study aimed to determine if a gelatin injectable with the reinnervating biomolecules will induce site-specific amplification of neurotrophic factor release and reinnervation after RLN injury in unilateral vocal fold paralysis.

Methods

C57BL/6 mice underwent RLN transection with the following treatment allocations: saline control (N = 16), biomolecule cocktail only (N = 16), and biomolecule-infused gelatin (N = …

Development Of A Water Temperature Modeling Platform To Support Short- And Long-Term Water Temperature Management In Reservoir-River Systems, Michael Deas, Yung-Hsin Sun, John Degeorge, Benjamin T. Saenz, Thomas A. Evans, Scott Burdick-Yahya, Stephen Andrews, Jeff Schuyler, William Candy, Lin Zheng, Scott Wells, Multiple Additional Authors

Civil and Environmental Engineering Faculty Publications and Presentations

The U.S. Department of the Interior, Bureau of Reclamation (Reclamation) supports water temperature management for fishery species protection in downstream river reaches below Central Valley Project (CVP) reservoirs in the Sacramento, American, and Stanislaus River systems. The Water Temperature Modeling Platform (WTMP) Project was initiated to modernize and enhance modeling capabilities to predict summer–fall water temperature through reservoir cold water pool management using temperature control facilities designed for temperature management. The WTMP supports forecasts, historical analyses, and long-term planning efforts and advances previous modeling approaches by using an integrated modeling platform. This platform includes a data management system that acquires …

Ontology Features-Based Arabic Text Augmentation Using Word2vec, Enas Tariq Khudair, Onsa Lazzez, Mourad Zaied, Tarek M. Hamdani, Ahmed T. Sadiq, Habib Chabchoub, Adel M. Alimi

Iraqi Journal for Computer Science and Mathematics

Text augmentation plays a major role when data is scarce. In this context, there are few Arabic news texts for specific purposes, and hence, there is a dire need to generate Arabic text, especially news. This paper presents an enhanced approach to Arabic text augmentation based on Arabic ontology features. The Arabic part of speech, particularly adjectives, verbs, and prepositions, and the ontology properties regarding such parts to create new texts, make up the first stage of the system, which has multiple stages. Word2Vector (Word2Vec) plays a pivotal role in giving Arabic ontology features to the specific Arabic Part of …

Activity Design Principles To Support Engineering Engagement For Families With Preschool-Age Children From Low-Income English-And Spanish-Speaking Communities, Scott A. Pattison, Smirla Ramos Montañez, Viviana López Burgos, Gina Svarovsky, María Quijano, Amy Corbett, Catherine Wagner, Diana Contreras

Journal of Pre-College Engineering Education Research (J-PEER)

Existing evidence highlights the significance of family STEM learning experiences during early childhood. However, there is a lack of research specific to early childhood family-based learning in the field of engineering, especially with preschool-age children (three to five years old). To address this gap and inform engineering education programs for young children, we conducted a design-based research study in collaboration with 15 Spanish-and English-speaking families with preschool-age children from low-income communities. Our study aimed to develop and test a series of family-based engineering design activities while also identifying underlying design principles. Guided by an asset-based family learning framework, which acknowledges …

Building Multimodal Knowledge Graphs: Automation For Enterprise Integration, Ritvik Garimella, Hong Yung Yip, Revathy Venkataramanan, Amit P. Sheth

Publications

As enterprises increasingly aim to incorporate artificial intelligence into their workflows to tackle complex, multimodal tasks, the demand for intelligent, robust, and trustworthy systems is paramount. While multimodal large language models offer initial capabilities for processing diverse data streams, their dependence on embedding-based representations limit their effectiveness in delivering semantically grounded explanations and reasoning, as well as qualities essential for enterprise-grade applications. Neurosymbolic approaches provide a promising alternative by enabling traceable, context-aware decision making. However, constructing enterprise-level multimodal knowledge graphs (MMKGs) that enable neurosymbolic approaches remains largely impractical. Although prior efforts have explored MMKG construction, they fall short in addressing …

The Green Approach Of Arabic Gum-Based Adsorbent In Wastewater Treatment, Atheel H. Alwash

AUIQ Technical Engineering Science

The natural polysaccharide Arabic gum is a multifunctional, sustainable material used widely in wastewater treatment technology. Its active functional groups such as hydroxyl, carboxyl, and amino groups facilitate the efficient removal of heavy metals, dyes, pesticides, pharmaceuticals, and persistent organic pollutants. The high surface area and active functional groups facilitate its modification to form various structures such as hydrogels, nanocomposites, or biochar integrated into hybrid adsorption–photocatalysis systems. This review highlights the most familiar forms of Arabic gum in wastewater treatment technology, such as hydrogels, hydrogels nanocomposite, stabilizing agents, coating agents, and bio-activated carbon derived from Arabic gum using different preparation …

A Pilot Study On Tissue Deformation Using An Integrated Sensor–Actuator Blood Collection Setup In Aquaculture (Salmo Salar), Ishrak Siddiquee, Md Ebne Al Ashad, Ahmed Hasnain Jalal

Electrical and Computer Engineering Faculty Publications

This pilot study presents a sensor–actuator setup designed to evaluate tissue deformation in Atlantic Salmon (Salmo salar) during needle insertion. The system integrates three types of low-cost, commercially available force sensors to capture force profiles and identify biomechanical events associated with tissue layer transitions. Controlled insertions were performed on a deceased specimen, and the resulting force data were analyzed to quantify insertion dynamics and estimate tissue deformation. A simulation model based on the recorded force values was developed to calculate stress distribution and deformation, which ranged from 0.001 µm to 8.4 µm and from 0.3 N/m2 to 4.9 N/m2, respectively. …

The Fate Of Intra- And Extracellular Antibiotic Resistance Genes Through Advanced Wastewater Treatment Process, Celestene Adrianne Sebag

Graduate Theses and Dissertations

More areas across the globe are becoming affected by water stress or water scarcity. The decrease in available freshwater due to overconsumption reveals the direct need to consider other sources for necessities such as drinking water or food production. Agricultural irrigation uses 70% of the world’s freshwater, making the focus on safe and reliable reclaimed water for agricultural reuse imperative. However, contaminants of emerging concern (CECs), such as antibiotics and their resulting antibiotic resistance genes (ARGs), can spread and affect human health if reclaimed water is not treated to the proper level. Antibiotics are widely used in human medicine and …

Preliminary Investigation Of The Potential Health Risks Of Non-Formfitting Body Armor With A Focus On Female Warfighters, Melissa Sutter, Catherine E. Johnson

Mining Engineering Faculty Research & Creative Works

Introduction Body armor is an important piece of protective equipment for warfighters in battlefield environments. With more women now filling military roles, body armor designs may need to be further refined to accommodate the female anatomy instead of the male-based unisex designs. Unisex designs have been found to have negative effects on female warfighter performance, resulting in discomfort, breathing difficulty, and air gaps forming between the armor and torso. This study aimed to investigate increased injury risk because of air gaps from shock wave exposure on warfighters wearing nonform-fitting armor and the influence of material properties. Based on literature, lowered …

Kentucky Model Minimum Uniform Crash Criteria (Mmucc) Sixth Edition Report Card, William Staats, Nikiforos Stamatiadis, Eric Green, Nathaniel Swallom

Kentucky Transportation Center Research Report

The National Highway Traffic Safety Administration published the Model Minimum Uniform Crash Criteria (6th Edition) (MMUCC) in 2024. This updated version of the MMUCC contains recommendations for improving and standardizing electronic crash data. Its guidelines address the collection and presentation of 105 data elements and 1,056 data attributes. To facilitate a possible redesign of Kentucky’s crash reporting process, Kentucky Transportation Center (KTC) researchers reviewed the updated criteria and evaluated the degree to which the state complies with its recommended methods of gathering, storing, and presenting crash data. At the level of data elements, Kentucky is 25 percent compliant; for data …

Kentucky Traffic Collision Facts Calendar Year 2024 Report, Paul Ross, Eric Green, Christopher Blackden, Kenneth Agent, Christopher Van Dyke

Kentucky Transportation Center Research Report

No abstract provided.

Comprehensive Review Of In Vitro Approaches For Environmental Heavy Metal Exposure, Manas Warke, Madeline English, Camila Padilla, Lexie Gasco, Wendy Leisner, Rupali Datta, Smitha Rao

Michigan Tech Publications

Heavy metals are ubiquitous environmental pollutants, contaminating air, soil, and water via the erosion of natural deposits, as well as originating from anthropogenic sources, such as agriculture, industries, transportation, and landfills. The increasing utilization of heavy metals over the years, combined with the persistent nature of metals in the environment poses a direct threat to human and environment health. Although regulatory limits have been established for toxic metals, assessing the associated health risks using real-life exposure scenarios remains challenging. In this review, we summarize the development and use of in vitro models based two- and three-dimensional cell culture systems, focusing …

Lung Injury Risk Curves From Behind Armor Blunt Trauma Using A Live Swine Model, Narayan Yoganandan, Lewis Somberg, Danielle Wilson, Alok Shah, Jared Michael Koser, Brian D. Stemper, Valeta Carol Chancey, Joseph Mcentire

Biomedical Engineering Faculty Research and Publications

Introduction

From structural, anatomical, and functional perspectives, components of the thoracoabdominal region are heterogeneous and physiologically and functionally different. Although their tolerances to injury are expected to be different, the current Roma Plastilina No. 1 clay penetration criterion for behind armor blunt trauma (BABT) is not specific to the body region. It is important to develop regional injury criteria to ensure its specificity. The objective of the study is to conduct impact tests on the lung region using a live animal model and develop injury risk curves using velocity and deflection metrics via parametric survival analysis.

Materials and Methods

Live …

Investigating The Impact Of Forest Vegetation On Nuclear Weapon Prompt Radiation Energy Deposition, Paul A. Clement

Theses and Dissertations

This work seeks to answer the unstudied questions “Does a layer of vegetation impact the prompt radiation energy deposition in the soil from an atmospheric nuclear detonation?” and “If yes, by how much?” A new methodology was developed to repeatably automate and streamline a process of generating a three-dimensional geometry for subsequent radiation transport simulations and statistical analysis. The methodology streamlined three diverse applications: a three-dimensional mesh generator, a radiation transport simulation code, and a sensitivity analysis & uncertainty quantification software. The methodology was tested by simulating the quantitative influence that vegetation has on changing the energy deposition into the …

Low-Resource Ecoacoustic Audio Classification, Enis Berk Coban

Dissertations, Theses, and Capstone Projects

Ecoacoustic monitoring via machine learning enables scalable analysis but is often constrained by labeled data scarcity, particularly in remote regions like the Arctic. This thesis confronts low-resource ecoacoustic audio classification by developing and evaluating complementary machine learning methodologies. We introduce EDANSA, the first publicly available, expert- labeled Arctic dataset of its kind, curated via novel active learning, alongside a baseline CNN. We systematically evaluate transfer learning, showing general audio embeddings effectively bootstrap classifiers for challenging Arctic sounds, significantly outperforming direct label mapping. Optimizing label utility, we investigate standard data augmentation and introduce novel audio data valuation via Shapley values, revealing …

Tissue Engineered Combinatorial Therapeutics For Spinal Cord Injury Repair, Inha Baek

Graduate Theses and Dissertations

Traumatic spinal cord injury (SCI) lead to temporary or permanent sensorimotor deficit due to the complex and multifaceted features of the injury site, making the treatments ineffective. Recent research emphasizes the potential of combinatorial therapeutics approaches combining different therapeutics, such as biomaterials and stem cell transplantation. In this context, nerve composite hydrogels, fabricated from decellularized sciatic nerve (dSN) and spinal cord (dSC) extracellular matrices (ECM), might be promising platforms due to their biocompatibility and ability to mimic native microenvironments. In this study, we developed and characterized nerve mimetic composite hydrogels embedded with human adipose-derived stem cells (hASCs) and investigated their …

Reduced Order Models Of Hydrodynamically Interacting Flapping Wings, Jose Pabon

Dissertations

Fish schools exhibit a collective behavior and self-organization that is mediated by hydrodynamic interactions between individual fish. However, the long-time evolution of hydrodynamically interacting collectives is challenging to investigate due to the persistent influence of long-lived vortical structures, and the high-resolution requirements of direct numerical simulation at large Reynolds numbers. Reduced-order models have therefore played an important role in theoretical investigations of collectives of swimming bodies. The main results detailed herein are several new reduced-order models of swimmers that self-propel by flapping, i.e., by executing a prescribed periodic rigid body motion. The models are extensions of a discrete-time dynamical system …

Low-Cost Cutaneous Protoporphyrin Ix (Ppix) Detection (Cpd) Device For Follow-Up Monitoring Of Patients After Photodynamic Therapy, Md Asaduzzaman Rasel

Graduate Masters Theses

Background: Photodynamic Therapy (PDT) utilizes specific wavelengths of light to activate photosensitizing chemical compounds, known as photosensitizers, which induce the generation of cytotoxic reactive oxygen species (ROS) for the targeted destruction of cancer cells. Among various photosensitizers for PDT, Protoporphyrin IX (PpIX) is widely employed in oncology and dermatology due to its natural in situ generation via the metabolic conversion of 5- aminolevulinic acid (ALA), a non-phototoxic prodrug. Systemic administration of ALA after 3-6 hr drug delay leads to peak PpIX accumulation in tissues, facilitating therapeutic and diagnostic applications. However, PpIX can persist in the skin for 24–48 hours post-treatment, …

A Green Concrete Mixture Using Rice Husk As Partially Cement Replacement, Khloud Khalid Eldamshiry, Zeina Salama, Amany Micheal, Rania Rushdy Moussa, Ayatallah Raafat

Architectural Engineering

Egypt's agricultural waste production has increased significantly in recent decades, leading to improper disposal methods and environmental pollution. Rice husks are the most common agricultural solid waste in Egypt, contributing to "black clouds" and causing health issues. On the other hand, Cement, a crucial component of construction materials, generates unsound residues and greenhouse gas emissions. Green concrete with rice husks could be a profitable solution for environmentally sound construction, reducing cement consumption and increasing the durability and integrity of new materials. This study investigates the use untreated rice husk fibres with a concrete mixture, avoiding burning and contributing to environmental …

Effect Of Contact Time And Concentration On Adsorption Of Pb2+Metal Ion Utilizing Crab Shell Chitosan And Activated Bentonite Clay Composite, Nia Sasria, Adi Wisaka, Ade Wahyu Yusariarta Putra Parmita, Gusti Umindya Nur Tajalla

Makara Journal of Technology

Indonesia produced 1,508 tons of nonliving crabs in the January–March 2020 period. The number of shells generated can account for 40%–60% of the overall weight. Therefore, using crab shells made into chitosan is expected to increase the economic value and reduce waste from crab shells. Chitosan can be modified with clay previously activated with an acid solution to form a chitosan–clay composite to improve the adsorption capacity. This study aims to analyze the differences in characteristics between chitosan and clay before and after the immobilization process. A comparison of chitosan and clay (1:2) is conducted on the basis of variations …

Human-Machine Communication: Complete Volume. Volume 10

Human-Machine Communication

This is the complete volume of HMC Volume 10.

The Emergence Of Ai Chatbots In Education, Trek Martin

Journal of Graduate Education Research

The recent advent of popular AI applications in educational contexts has sparked renewed interest in the question of AI and guided learning platforms as teaching tools. What are the possibilities for learning? In the attempt to answer that question, limitations of the field must be brought to full attention, as well an understanding of whether or not those limitations will continue into the immediate future; this research examines the technical evolution of artificial intelligence in education, from early symbolic reasoning systems to modern machine-learning-based chatbots. It then examines that evolution in terms of the key challenges it faced throughout, and …

Modeling, Control, And Learning For Whole-Body Manipulation With Large-Scale Soft Robots, Curtis C. Johnson

Theses and Dissertations

This dissertation addresses the challenge of enabling soft robots to perform contact-rich manipulation tasks by overcoming limitations in hardware, modeling, control, and learning. First, we present hardware advancements with PneuDrive, a pneumatic control system for actuating soft robots. We also introduce Baloo, a hybrid soft-rigid robotic torso which achieves a single-arm payload capacity of 19.3 kg and robust whole-body grasping capabilities. We also develop a full-body tactile sensing system enabling piezoresistive sensor arrays to cover large areas (1 square meter) with over 8000 distributed sensing points. Second, we focus on developing tractable dynamic models based on the Recursive Newton-Euler algorithm …

Computational Fluid Dynamics (Cfd) Modeling For Bio-Inspired Aerodynamic Optimization In Autonomous Drones, Hyginus C.O. Unegbu, Danjuma Saleh Yawas

Makara Journal of Technology

This study explores the aerodynamic benefits of bio-inspired design modifications for autonomous drones using advanced Computational Fluid Dynamics (CFD) simulations. Four bio-inspired configurations—leading-edge serrations, winglets, riblet surfaces, and curved wings—were assessed and compared against a baseline drone model to evaluate their impact on aerodynamic performance. The results indicated that all bio-inspired designs significantly enhanced lift, reduced drag, and improved overall aerodynamic efficiency. The leading-edge serration configuration achieved the highest performance gains, with a 33.6% increase in maximum lift coefficient (CL) and a 29.5% improvement in lift-to-drag ratio (CL/CD), primarily due to delayed flow separation and reduced turbulence. Winglets minimized wingtip …

Advancing Rfid Systems: From Head Orientation To Robotic Localization Using Passive Tags, Guilherme Ricardo Mendes Da Silva Barreto De Figueiredo

Doctoral Dissertations

No abstract provided.

Retracted: Efficient Multi-User Computation Offloading And Reducing Latency In Mobile-Edge Computing For Iot Applications, Sarmad T. Abdul-Samad, Osamah Al-Hwaidi, Ali Abd Al-Rasool Muslem

Iraqi Journal for Computer Science and Mathematics

Mobile Edge Computing (MEC) is an inventive paradigm for computing that has the potential to notably diminish latency and energy consumption by transferring computationally demanding jobs to edge clouds near intelligent mobile users. This investigation aims to reduce offloading and latency between multiple users and edge computing in the context of Internet of Things (IoT) applications in the fifth generation (5G) by utilizing an optimization algorithm called the Bald Eagle Search Optimization Algorithm. Although employing deep learning methods might increase time consumption and computational complexity, an edge computing system enables devices to transfer their demanding jobs to edge servers, decreasing …

Polymeric Nanocarriers Functionalized With Peptides For Improved Glioblastoma Targeting And Blood–Brain Barrier Permeability, Cristian Antonio Wieczorek Villas Boas, Aaron Priester, Buck E. Rogers, Anthony J. Convertine

Materials Science and Engineering Faculty Research & Creative Works

We report the synthesis of polymeric conjugates designed to penetrate the blood–brain barrier (BBB) and selectively bind glioblastoma (GBM) cells through reversible addition–fragmentation chain transfer (RAFT) polymerization. The resulting materials were engineered to contain peptide macromonomers for cell-specific targeting and integrated DOTA units to facilitate radiolabeling with copper-64 (⁶⁴Cu), yielding radiolabeled conjugates with greater than 95% radiochemical purity. In biodistribution assessments conducted in mice, C1C2 peptide-conjugated polymers showed significantly improved accumulation in brain tissue, supported by brain perfusion analyses confirming efficient BBB penetration. Additionally, flow cytometry evaluations demonstrated specific affinity of GBM-targeted polymer formulations toward U87 glioblastoma cells. …