Digital Commons Network^™

Sex-Driven Alterations In Aging Alpha Motoneurons: Exploring Size, Type, Density, And Kv2.1 Channel Expression, Kalin R. Gerber

Browse all Theses and Dissertations

This research explores how motor neurons (MNs) and Kv2.1 clustering change with age, emphasizing sex differences and MN subtypes. We found that MN density decreases with age in both sexes, while soma size increases in male mice. FF MNs were the most affected, and old weak mice had smaller MNs than their stronger counterparts, underscoring FF MN vulnerability. Baseline studies revealed that FF and FI MNs have larger Kv2.1 clusters compared to FR and S MNs. Female mice had smaller, denser Kv2.1 clusters than male mice, suggesting less clustering in females. With age, Kv2.1 clusters grew larger but became less …

Development Of Novel Hydrogel Materials For Viscoelastically Accurate Brain Phantoms, Lila G. Schandler

Theses and Dissertations

Current methods such as concussion tests and Magnetic Resonance Imaging (MRI) scans only reveal structural damage post-injury. Creating an anatomically accurate model of the brain that mimics brain structure and viscoelastic properties will further allow medical professionals to analyze concussion events and create curated and personalized plans of recovery for a patient’s unique brain injury.

Values have been established for the necessary viscoelastic properties (time constants and elasticity) to mimic the native human brain tissue such as grey matter and white matter. The mechanical properties of the hydrogel are tunable by varying the concentration of Phytagel (PHY), a protein binding …

Initial Solution Improvements To A Tethered Robotic Path Planner Using Random Geometric Graph Configurations And Biased Sampling, Austen J. Goddu

Dissertations, Master's Theses and Master's Reports

With NASA's ongoing efforts to establish a presence on the lunar surface to eventually move on to exploring mars, the development of intelligent robotic systems is more important than ever. The ability of robotics to explore hazardous and extreme terrain, coupled with long communication times from earth places an ever increasing need on more robust and efficient autonomy. Tethered robotics offer unique advantages to explore scientific targets both on the lunar and martian surfaces, capable of using their tether as a physical or metaphorical lifeline to allow the exploration of slopes, extreme dark regions, or areas in which wireless communication …

Designing A Visual Control Framework Based On Feature Point Analysis To Guide Robots In Uncharted Areas, Isam Sadiq Rasham Al-Ghadhbawi

Al-Esraa University College Journal for Engineering Sciences

Image processing may be made more accurate and efficient with the use of optical processing technologies. In order to make better design judgments early in the package design process, visual packaging art simulation aims to swiftly develop realistic packaging effects. Conventional simulation techniques frequently yield findings that are neither realistic or detailed, and they also take a lot of time and human resources. Optical processing-based machine vision technology can fully utilize computer vision and image processing techniques to simulate package designs accurately and efficiently. This research proposes a foundation for machine vision technologies based on image optical processing. Real package …

Vertical Farming: A Key To Sustainable Compact Cities, Mohab Taher Abdelfatah, Sahar Mahmoud El-Arnaouty, Akram Abdelhakim Zayan

Mansoura Engineering Journal

Urbanization continues to surge, with projections indicating that by 2050, around 70 percent of the global population will reside in urban areas. In response, urban planners are exploring novel urban paradigms to ensure food security through urban agriculture, a cornerstone of sustainable development encompassing environmental, economic, and social dimensions. This study addresses a critical research gap within urban agriculture, conducting a comparative analysis between horizontal and vertical farming methodologies within urban contexts. By categorizing various typologies of vertical farming, from container farms to mixed-use structures, this research highlights their distinct contributions to sustainable urban development. Emphasis is placed on vertical …

The Impact Of Social Media On Charitable Giving For Nonprofit Organization, Namchul Shin

Journal of International Technology and Information Management

Research has extensively studied nonprofit organizations’ use of social media for communications and interactions with supporters. However, there has been limited research examining the impact of social media on charitable giving. This research attempts to address the gap by empirically examining the relationship between the use of social media and charitable giving for nonprofit organizations. We employ a data set of the Nonprofit Times’ top 100 nonprofits ranked by total revenue for the empirical analysis. As measures for social media traction, i.e., how extensively nonprofits draw supporters on their social media sites, we use Facebook Likes, Twitter Followers, and Instagram …

Inaugural Future Of Bse Days: Workshop Report, Mark Stone

Department of Agricultural and Biological Systems Engineering: Presentations and White Papers

The inaugural Future of BSE Days (FBD) event, held on May 2-3, 2024, brought together the Biological Systems Engineering (BSE) community to discuss and shape the future of work and learning within the field. The event was designed to foster collaboration between faculty, students, industry leaders, and alumni, with the goal of reimagining the department’s educational approach, enhancing industry partnerships, and preparing students for the challenges of tomorrow. Over the course of two days, participants engaged in insightful discussions, workshops, and presentations that highlighted both the strengths of the department and opportunities for growth.

The workshop resulted in several key …

Classification Of Sow Postures Using Convolutional Neural Network And Depth Images, Md Towfiqur Rahman, Tami M. Brown-Brandl, Gary A. Rohrer, Sudhendu R. Sharma, Yeyin Shi

Department of Agricultural and Biological Systems Engineering: Faculty Publications

The United States swine industry reports an average preweaning mortality of approximately 16% where approximately 6% of them are attributed to piglets overlayed by sows. Detecting postural transitions and estimating sows’ time budgets for different postures are valuable information for breeders and engineering design of farrowing facilities to eventually reduce piglet death. Computer vision tools can help monitor changes in animal posture accurately and efficiently. To create a more robust system and eliminate varying lighting issues within a day including daytime/ nighttime differences, there is an advantage to using depth cameras over digital cameras. In this study, a computer vision …

Characterization Of Recent Wild Pig‑Vehicle Collisions In Georgia, Usa, Jeremiah L. Psiropoulos, Emily Howe, John J. Mayer, Sophie C. Mckee

United States Department of Agriculture Wildlife Services: Staff Publications

Vehicle collisions with wild pigs (Sus scrofa) are reported almost everywhere this species is found. However, this is one of the least studied and characterized forms of damage that these invasive animals cause in the United States (US). We analyzed 518 wild pig-vehicle collisions (WPVCs) that took place statewide in Georgia between 2015 and 2021. From that dataset, we analyzed several parameters in order to better understand and characterize these accidents on a scale that had previously not been done in the US. Wild pig-vehicle collisions were reported from 105 out of the 159 counties in Georgia, increasing …

Reinstatement Of The Poly Canyon Caretaker Program Through The Development Of A Tiny Home Community, Leily Martin

Construction Management

The Poly Canyon Experimental Structures Laboratory, through its Design/Build program, is unique in the educational opportunity it provides Cal Poly College of Architecture and Environmental Design (CAED) students. However, since the conclusion of the Caretaker Program in 2011, the facility’s structures have deteriorated due to vandalism, purposeful destruction, and weathering. This study examines the perspectives of CAED students, the interim CAED Dean, Kevin Dong, and Cal Poly Risk Manager, Mike Morgan, on the effectiveness in reinstating the Caretaker Program through the development of a tiny home community. Results indicated educational value in this facility, so addressing these issues must occur …

Receptor-Targeted Next-Generation Probiotics Ameliorate Mammalian Colitis, Nicholas L. F. Gallina, Vignesh Nathan, Akshay Krishnakumar, Dongqi Liu, Rishi Drolia, Nicole Irrizary Tardi, Yang Fu, Manalee Samadar, Shivendra Tenguria, Alvin Cai, Ruth Eunice Centeno-Martinez, Timothy A. Johnson, Abigail Cox, Lavanya Reddivari, Bruce Applegate, Xingjian Bai, Luping Xu, Deepti Tanjore, Ramesh Vemulapalli, Rahim Rahimi, Arun K. Bhunia

Biological Sciences Faculty Publications

Introduction: a loss of intestinal barrier function, inflammation, and an elevated expression of epithelial heat shock protein 60 (Hsp60) are features of an inflamed bowel. Probiotics have been used to alleviate colitis-induced pathologies, but offer poor adhesion and adaptation to the diseased gut. We hypothesize that enhancing probiotic adhesion in the inflamed bowel may ameliorate such pathologies. Listeria adhesion protein (LAP; 94-kDa acetaldehyde alcohol dehydrogenase) aids Listeria attachment to the epithelial cells by interacting with the mammalian receptor Hsp60. Bioengineered Lactobacillus casei probiotics (BLPs) expressing LAP showed strong interaction with epithelial Hsp60, a high immunomodulatory response, and sustained epithelial barrier …

Influence Maximization Using Triadic Closures, Communities, And Quotas, Matthew Fu

Master's Projects

Online social networks have exploded in popularity in the last decade. In addition, traditional advertising methods such as television advertising have greatly decreased. This allows companies to utilize viral marketing more effectively. With viral marketing, companies can spread information on a product to a social network by reaching out to a small group of early adopters, who will go on to inform the people around them of the product. The problem is selecting the early adopters that can maximize the spread of influence. The Influence Maximization (IM) problem is finding a social network’s most influential (early adopters) starting nodes, called …

Gesture Recognition Dynamics: Unveiling Video Patterns With Deep Learning, Nithish Reddy Agumamidi

Master's Projects

This paper, Gesture Recognition Dynamics: Revealing Video Patterns with Deep Learning, explores the combination of Long Short-Term Memory(LSTM) with Convolutional Neural Network(CNN) in the identification of convoluted human activities. The study assesses LSTM’s capability to capture temporal dependencies and CNN’s potential to apprehend and extract spatial characteristics to detect the gestures from UCF50. It further evaluates the architecture linkage of LSTM and CNN, which will improve the analytical capacity to interpret and validate dynamic gesture trends. The paper utilizes Mediapipe, an open-source framework created by Google specifically designed for extracting poses. The Mediapipe tool is well-designed to track important body …

Deciphering Speech Through Vision: A Deep Learning Lip Reading System, Srujith Rao Ambati

Master's Projects

Lip-reading, a ubiquitous field between computer vision and speech processing, focuses on identifying what spoken words a person generates depending on their uttering lip movements. This paper presents a streamlined lip-reading solution that employs machine learning and deep learning. First, Our work utilizes the Multi-Task Cascaded Convo- lutional Networks to detect facial “landmarks,” including the face and lips region, and the aligns the face. The aligned faces are segmented to get the lip images. Lip images are preprocessed using the Real-Enhanced Super Resolution Generative Adversarial Network to enhance image resolution to identify subtle lip movement in video images: a critical …

Multi-Platform Cyberbullying Detection Using Nlp And Machine Learning, Chinmayi Lokeshwar Hegde

Master's Projects

The issue of cyberbullying is growing due to the online anonymity and due to online platforms having less repercussions. This research proposes for proactive measures to detect and prevent such behavior before it reaches the victim. By using data from various social media platforms and employing machine learning techniques, this research proposes an innovative system aimed at identifying and thwarting cyberbullying incidents preemptively. While existing methods have primarily focused on prediction and detection of cyberbullying incidents, there remains a significant gap in research regarding prevention strategies. This project aims to address this gap by leveraging machine learning, natural language processing …

Personalizing Image Generation From Prompts Using Generative Ai, Mit Ramesh Jain

Master's Projects

The rapid advancements in Generative AI, particularly Text-to-Image (T2I) models, have opened up new possibilities for personalized image generation. Finetuning large T2I models for specific downstream tasks is a key approach to achieving tailored outputs. In recent years, Parameter-Efficient Fine-Tuning (PEFT) techniques have gained significant attention as a cost-effective and efficient solution for fine-tuning large models. Initially developed for fine-tuning large language models (LLMs), PEFT techniques have been extensively studied and compared in the context of language tasks. However, regarding the T2I domain, there is a lack of similarly exhaustive and detailed literature on PEFT. This research project, in the …

Optimizing Web Design Code Generation: A Comparative Study Of Finetuning, Pretrained Models, And Rag (Retrieval Augmented Generation), Srinivas Rao Chavan

Master's Projects

Website Creation is revolutionized by automated code generation, reducing the development effort, speeding the production process, and ensuring consistency in design. Automated web design code generation has emerged as a transformative tool bridging the gap between design and development. In this research, a website design tool is developed and used to create visual layouts, exporting them as JSON designs. These JSON outputs were then transformed into textual prompts, optimized using established HCI principles and UI/UX rules to ensure consistency, visual hierarchy, aesthetics and minimalistic design, accessibility, user-friendly navigation and flexibility. These generated prompts were fed into large language models for …

Integrating Chatgpt With A-Frame For User-Driven 3d Modeling, Ivan Hernandez

Master's Projects

ChatGPT is a large language model that is capable of creating conversational text and functional code that can be integrated into various technologies, including computer graphics software. Currently, 3D modeling applications can be relatively difficult for novices to learn and understand due to the overwhelming amount of graphical user interfaces. However, we can remedy this issue by leveraging ChatGPT’s conversational language capabilities. Our project described in this report integrates ChatGPT with A-Frame, an online framework for developing virtual reality experiences, to create an immersive and user-friendly 3D modeling environment where users can create and modify 3D models through natural language …

Noteblocklib: A Library For Physics- And Animation-Driven Virtual Midi Instruments For Use In Video Games, Kevin Rotunni

Master's Projects

To better capture the relationship between the performer of a piece of music and the music itself in a video game context, I have designed NoteBlockLib, a system by which MIDI instructions are generated and processed in real time based on the motion and collision data of in-game objects. Ultimately, the movement of instruments made using this system would be driven by the animations of a character in the game. This system would thus allow the player character to interact with the performer in the game without sacrificing the relationship between the performer’s actions and the resulting music or to …

Birdsong Classification Using Deep Learning And Mixit, Sasanka Kosuru

Master's Projects

The identification of bird species using deep learning techniques presents a novel approach in bioacoustics, by significantly advancing our understanding and enhancing our capabilities in bird species recognition from audio recordings. The value of audio over visual data for monitoring ecological patterns in birds can be highlighted with the deployment of automated recording devices in remote wildlife sensing, offering a more cost-effective, non-invasive, and practical solution. However, the methods of processing and classifying the audio remain challenging due to the complexity of bird audio, characterized by diverse vocalizations and imminent environmental noise, which poses difficult challenges to perform effective classification. …

Prediction Of Chlorophyll-A As An Index Of Harmful Algal Blooms Using Machine Learning Models, Ibrahim Busari, Debrabata Sahoo, R. Daren Harmel, Brian E. Haggard

Biological and Agricultural Engineering Faculty Publications and Presentations

The complex dynamics of freshwater harmful algal blooms (HABs) necessitate proactive monitoring approaches to mitigate their impacts. The rapid breakthrough in computing prowess and statistical advances is triggering the development of data-driven techniques such as machine learning (ML) models, which have been shown in different fields to be instrumental in finding patterns for explaining relationships in observed data. This study assesses the ability of ML models for HABs monitoring in a lake using chlorophyll-a concentration as the index. The selected models for this study were regression tree, random forest (RF), multilayer perceptron (MLP), support vector regression (SVR), long short-term memory …

Heating Capacity And Biocompatibility Of Hybrid Nanoparticles For Magnetic Hyperthermia Treatment, Aline Alexandrina Gomes, Thalita Marcolan Valverde, Vagner De Oliveira Machado, Emanueli Do Nascimento Da Silva, Daniele Alves Fagundes, Fernanda De Paula Oliveira, Erico Freitas, José Domingos Ardisson, José Maria Da Fonte Ferreira, Junnia Alvarenga De Carvalho Oliveira, Eliza Rocha Gomes, Caio Fabrini Rodrigues, Alfredo Miranda De Goes, Rosana Zacarias Domingues, Ângela Leão Andrade

Michigan Tech Publications

Cancer is one of the deadliest diseases worldwide and has been responsible for millions of deaths. However, developing a satisfactory smart multifunctional material combining different strategies to kill cancer cells poses a challenge. This work aims at filling this gap by developing a composite material for cancer treatment through hyperthermia and drug release. With this purpose, magnetic nanoparticles were coated with a polymer matrix consisting of poly (L-co-D,L lactic acid-co-trimethylene carbonate) and a poly(ethylene oxide)–poly(propylene oxide)–poly(ethylene oxide) triblock copolymer. High-resolution transmission electron microscopy and selected area electron diffraction confirmed magnetite to be the only iron oxide in the sample. Cytotoxicity …

Advancing Household Robotics: Deep Interactive Reinforcement Learning For Efficient Training And Enhanced Performance, Arpita Soni, Sujatha Alla, Suresh Dodda, Hemanth Volikatla

Engineering Management & Systems Engineering Faculty Publications

The market for domestic robots—made to perform household chore, is growing as these robots relieve people of everyday responsibilities. Domestic robots are generally welcomed for their role in easing human labour, in contrast to industrial robots, which are frequently criticised for displacing human workers. But before these robots can carry out domestic chores, they need to become proficient in a number of minor activities, such as recognizing their surroundings, making decisions, and picking up on human behaviours. Reinforcement learning, or RL, has emerged as a key robotics technology that enables robots to interact with their environment and learn how to …

Effects Of Crate Size On Mortality And Postural Behavior In Post-Farrowing Sows, Md Towfiqur Rahman, Tami M. Brown-Brandl, Gary A. Rohrer, Sudhendu R. Sharma, Yeyin Shi

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Preweaning mortality (PWM) is a economic and animal well-being issue for swine producers in the US. On average, producers face about a 16% pre-weaning mortality. A significant portion of this, around 6%, is because sows accidentally overlay their piglets in farrowing crates. The posture behavior of sow plays a vital role in overlaying piglets and this behavior has a significant effect on farrowing crate dimensions. This study aims to explore the interplay between farrowing crate size, mortality rates, and postural behavior in post-farrowing sows. This study employed three farrowing stalls: Traditional (T), Expanded creep area (C), and Expanded sow area …

A Chemistry-Transport Model Study For Source Contributions Of Pm2.5 And Its Implications For Southeast Asia Regional Haze Management Policy, Abdul Wahab

Chulalongkorn University Theses and Dissertations (Chula ETD)

PM2.5 pollution is a persistent issue in Southeast Asia. In response, the Association of Southeast Asian Nations (ASEAN) launched the Second Hazefree Roadmap (2023-2030) to alleviate this issue. This roadmap can be an important institutional measure to reduce PM2.5 pollution regionally; however, it largely centres on biomass burning and does not comprehensively tackle other sources. This study aims to quantify the contributions of three key sectors—biomass burning, transport, and industry—to PM2.5 pollution. In addition, for the focus of Thailand, the study assesses transboundary PM2.5 pollution coming into Thailand. We employ the GEOS-Chem chemistry transport model, a widely used global model …

การพัฒนาแพลตฟอร์มเมตาเวิร์สแบบเว็บที่มีระบบสนับสนุนปัญญาประดิษฐ์, สืบพงศ์ น้อยศรี

Chulalongkorn University Theses and Dissertations (Chula ETD)

วิทยานิพนธ์ฉบับนี้นำเสนอการพัฒนาต้นแบบแพลตฟอร์มเมตาเวิร์สที่มีขีดความสามารถขั้นพื้นฐานครอบคลุมระบบอวาทาร์ ระบบผู้ใช้หลายราย ระบบสื่อสารตามเวลา ระบบการเชื่อมต่อแชตบอต และฉากโลกเสมือนจริงสามมิติที่เหมือนจริง แพลตฟอร์มที่พัฒนาขึ้นนี้ถูกนำไปใช้ประโยชน์กับหน่วยงานภาคการศึกษาและภาคธุรกิจ ทั้งหน่วยงานภายในจุฬาลงกรณ์มหาวิทยาลัยและสถาบันการศึกษาทั้งในประเทศและระดับนานาชาติ ผลการทดสอบพบว่าระบบทำงานได้ให้ผลสัมฤทธิ์ที่ดีและมีคุณภาพตามความต้องการใช้งานในทางปฏิบัติ สามารถประยุกต์ใช้กับการสร้างห้องเรียนเสมือนออนไลน์ในโลกเสมือนจริง รองรับระบบการสื่อสารระหว่างผู้ใช้ทั้งภาพ เสียง และข้อความ อีกทั้งยังสามารถใช้งานร่วมกับระบบแชตบอตจากภายนอกได้ผ่านระบบเอพีไอที่พัฒนาขึ้น ผลการทดสอบบนระบบคลาวด์ของบริษัท โทรคมนาคมแห่งชาติ จำกัด แสดงให้เห็นว่าระบบสามารถรองรับปริมาณผู้ใช้งานได้ไม่น้อยกว่า 30 รายพร้อมกัน ผลการทดสอบในเชิงประสบการณ์การใช้งานมีระดับความพึงพอใจในเชิงบวก งานวิจัยและพัฒนาจึงให้ประโยชน์และเป็นจุดเริ่มต้นของการประยุกต์ใช้เทคโนโลยีเมตาเวิร์สในวงกว้าง

Using Mechanical Interventions To Enhance Drug Transport To Bone Tumors, Michelle Gelbs

Dissertations and Theses

Bone metastasis occurs when cancer cells spread from a primary site to a secondary location in bone. Current treatments for metastatic bone tumors typically involve systemic chemotherapy, bisphosphonates, radiotherapy, or surgery; however, due to morphological changes in the tumor microenvironment and elevated interstitial fluid pressure, tissue penetration of therapeutic agents is often more limited in cancerous tumors compared to normal tissue. Weight-bearing mechanical loading applied to bone, as well as other mechanical stimulations such as vibration, have been shown to cause loading-induced bone deformations that increase convective transport via interstitial fluid flow. We hypothesize that mechanical loading can increase the …

Modulation Of Motor Learning With High-Intensity Transcranial Electric Stimulation, Gavin Hsu

Dissertations and Theses

Research thus far on noninvasive, transcranial electric stimulation have produced mixed results from in vivo human experiments. This work tests the hypothesis that applying higher stimulation intensities would induce intracranial electric fields that more closely match the higher magnitudes used in animal and in vitro studies and subsequently yield more robust effects. As done commonly in the literature, we targeted the motor cortex (M1), specifically in the context of neuroplastic changes taking place during motor learning in healthy adult humans. This work also seeks a better understanding of the neural correlates underlying motor skill learning.

Through multiple large-sample studies, this …

Mechanisms For Regenerative Intervertebral Disc Healing During Early Growth In Mice, Danielle N. D'Erminio

Dissertations and Theses

Annulus Fibrosus (AF) defects of intervertebral discs (IVDs) cause painful disability, for example when herniated tissue compresses against adjacent nerves. Discectomy, the current standard of treatment to address herniation, does not repair AF defects and can result in re-herniation and recurrent pain. As such there is a need for improved AF repair strategies. It has previously been established that neonatal mice functionally regenerate following severe AF injury providing a model of successful innate AF repair processes that contrasts the poor healing of adult mice. This dissertation focuses on identifying mechanisms of AF regenerative healing in neonatal mice subjected to severe …

Understand The Structure-Water-Responsive Relationship By Engineering Silk Materials, Yeojin Jung

Dissertations and Theses

Water-responsive (WR) materials mechanically swell and shrink in response to changes in relative humidity, and they have demonstrated the capability to exert higher actuation energy than conventional actuators and artificial muscles. As a result, WR materials have recently gained attention as potential high-energy actuating components for engineering applications. Despite the growing interest in this emerging category of WR materials, the fundamental WR mechanism of their significant performance is still not fully understood, limiting the ability to rationally design engineered systems. This dissertation presents three approaches for understanding the water-responsiveness of materials by engineering Bombyx (B.) mori silkworm silk protein. First, …