Digital Commons Network^™

Development Of A Dynamic In Vitro Model Of A Stented Blood Vessel To Evaluate The Effects Of Stent Strut Material Selection And Surface Coating On Smooth Muscle Cell Response, Bradley Winn

All Dissertations

Cardiovascular disease is the leading cause of mortality in The United States and Europe, accounting for approximately half of all deaths. The most common form of cardiovascular disease is atherosclerosis, which is characterized by the formation of fatty atheromatous plaques that can grow to occlude the vessel lumen, thus causing ischemia distal to the occlusion. This is commonly treated using balloon angioplasty, which is usually done in conjunction with the deployment of a stent. Stent deployment helps hold the vessel open following the local injury caused by balloon inflation and prevents elastic recoil and subsequent negative remodeling. Stenting has been …

Automated Digital Machining For Parallel Processors, Joshua Tarbutton

All Dissertations

When a process engineer creates a tool path a number of fixed decisions are made that inevitably produce sub-optimal results. This is because it is impossible to process all of the tradeoffs before generating the tool path. The research presents a methodology to support a process engineers attempt to generate optimal tool paths by performing automated digital machining and analysis. This methodology automatically generates and evaluates tool paths based on parallel processing of digital part models and generalized cutting geometry. Digital part models are created by voxelizing STL files and the resulting digital part surfaces are obtained based on casting …

The Evaluation And Analysis Of The Impact Of Variability On The Twelve Workstation Factory, Hernando Garrido

Theses and Dissertations - UTB/UTPA

Presently, there is theory and work examples about factory performance presented in the book ―Optimizing factory Performance‖ by James Ignizio, Ph.D. The theory explains how to determine performance using three fundamental equations by considering the impact and propagation of variability through a 12-Workstation Factory Model, and a number of its variations. The objective of developing a simulation model was to serve as a tool for instructors to illustrate the impact and propagation of variability in the manufacturing industry and to investigate phenomena (i.e., time to reach steady state, impact of variability) in the three dimensions of manufacturing. The validation of …

On The Pooling Of Positive Examples With Ontology For Visual Concept Learning, Shiai Zhu, Chong-Wah Ngo, Yu-Gang Jiang

Research Collection School Of Computing and Information Systems

A common obstacle in effective learning of visual concept classifiers is the scarcity of positive training examples due to expensive labeling cost. This paper explores the sampling of weakly tagged web images for concept learning without human assistance. In particular, ontology knowledge is incorporated for semantic pooling of positive examples from ontologically neighboring concepts. This effectively widens the coverage of the positive samples with visually more diversified content, which is important for learning a good concept classifier. We experiment with two learning strategies: aggregate and incremental. The former strategy re-trains a new classifier by combining existing and newly collected examples, …

Improved Stereo Vision Methods For Fpga-Based Computing Platforms, Wade S. Fife

Theses and Dissertations

Stereo vision is a very useful, yet challenging technology for a wide variety of applications. One of the greatest challenges is meeting the computational demands of stereo vision applications that require real-time performance. The FPGA (Field Programmable Gate Array) is a readily-available technology that allows many stereo vision methods to be implemented while meeting the strict real-time performance requirements of some applications. Some of the best results have been obtained using non-parametric stereo correlation methods, such as the rank and census transform. Yet relatively little work has been done to study these methods or to propose new algorithms based on …

Session 1 Presentation: Ocean Testing Of A Power-Capturing Wave Buoy, Kathleen Edwards

Ocean Waves Workshop

No abstract provided.

Bearing-Only Cooperative-Localization And Path-Planning Of Ground And Aerial Robots, Rajnikant Sharma

Theses and Dissertations

In this dissertation, we focus on two fundamental problems related to the navigation of ground robots and small Unmanned Aerial Vehicle (UAVs): cooperative localization and path planning. The theme running through in all of the work is the use of bearing only sensors, with a focus on monocular video cameras mounted on ground robots and UAVs. To begin with, we derive the conditions for the complete observability of the bearing-only cooperative localization problem. The key element of this analysis is the Relative Position Measurement Graph (RPMG). The nodes of an RPMG represent vehicle states and the edges represent bearing measurements …

Investigation Of Biomolecular Interactions For Development Of Sensors And Diagnostics, Xiaojuan Zhang

Theses and Dissertations

The highly specific recognition processes between biomolecules mediate various crucial biological processes. Uncovering the molecular basis of these interactions is of great fundamental and applied importance. This research work focuses on understanding the interactions of several biomolecular recognition systems and processes that can provide fundamental information to aid in the rational design of sensing and molecular recognition tools. Initially, a reliable and versatile platform was developed to investigate biomolecular interactions at a molecular level. This involved several techniques, including biomolecule functionalization to enable attachment to self-assembled monolayers as well as atomic force microscopy (AFM) based force spectroscopy to uncover the …

Cassava Pulp As A Biofuel Feedstock Of An Enzymatic Hydrolysis Proces, Djuma’Ali Djuma’Ali, Nonot Soewarno, Sumarno Sumarno, Dyah Primarini, Wahono Sumaryono

Makara Journal of Technology

Cassava pulp, a low cost solid byproduct of cassava starch industry, has been proposed as a high potential ethanolic fermentation substrate due to its high residual starch level, low ash content and small particle size of the lignocellulosic fibers. As the economic feasibility depends on complete degradation of the polysaccharides to fermentable glucose, the comparative hydrolytic potential of cassava pulp by six commercial enzymes were studied. Raw cassava pulp (12% w/v, particle sizeμm) hydrolyzed by both commercial pectinolytic (1) and amylolytic (2) enzymes cocktail, yielded 70.06% DE. Hydrothermal treatment of cassava pulp enhanced its susceptibility to enzymatic cleavageas compared to …

Migration And Invasion Of Brain Tumors, Richard A. Able, Jr., Veronica Dudu, Maribel Vazquez

Publications and Research

Recent advances in molecular biology have led to new insights in the development, growth and infiltrative behaviors of primary brain tumors (Demuth and Berens, 2004; Huse and Holland, 2010; Johnson et al., 2009; Kanu et al., 2009). These tumors are derived from various brain cell lineages and have been historically classified on the basis of morphological and, more recently, immunohistochemical features with less emphasis on their underlying molecular pathogenesis (Huse and Holland, 2010). The detailed molecular characterization of brain tumors has laid the groundwork for augmentation of standard treatment with patient-specific designed targeted therapies (Johnson et al., 2009; Kanu et …

Engineering On The Rose Float: Final Project Report, Stephen Boles, Garrett Dong, Peter Hoonhout

Mechanical Engineering

The purpose of this project is to design the simple mechanical movement systems of the 2012 Cal Poly Tournament of Roses Float Parade to prevent failure. Three mechanisms were designed. One of the mechanisms is a tall building that has a superhero and helicopter rotating around the top; it also has the ability to rotate the top 2/3^rds of the mechanism to a 90 degree angle to fit under a 16.5 foot bridge. Another mechanism is the cars that look like they are driving on the pod’s road surface via train tracks underneath the surface. The cars will travel …

Differential Il-21 Signaling In Apcs Leads To Disparate Th17 Differentiation In Diabetes-Susceptible Nod And Diabetes-Resistant Nod.Idd3 Mice., Sue M. Liu, David H. Lee, Jenna M. Sullivan, Denise Chung, Anneli Jäger, Bennett O V. Shum, Nora E. Sarvetnick, Ana C. Anderson, Vijay K. Kuchroo

Journal Articles: Regenerative Medicine

Type 1 diabetes (T1D) is an autoimmune disease that shows familial aggregation in humans and likely has genetic determinants. Disease linkage studies have revealed many susceptibility loci for T1D in mice and humans. The mouse T1D susceptibility locus insulin-dependent diabetes susceptibility 3 (Idd3), which has a homologous genetic interval in humans, encodes cytokine genes Il2 and Il21 and regulates diabetes and other autoimmune diseases; however, the cellular and molecular mechanisms of this regulation are still being elucidated. Here we show that T cells from NOD mice produce more Il21 and less Il2 and exhibit enhanced Th17 cell generation compared with …

Detecting Suspicious Behavior With Low-Cost Sensors, Ahren Alexander Reed

Master's Theses

A proof of concept is created that demonstrates how low-cost sensors and a simple software solution can be used to proactively detect IED placement. The main goal is to detect suspicious behavior; Specifically we derive requirements that loitering, meandering, improper location and object placement shall be detected. Current methods being used to detect Improvised Explosive Devices (IEDs) are costly in terms of equipment and risk to life, and many are retroactive; IED detection occurs long after explosives are placed. A prototype system is explored with the quality attributes of being low-cost, proactive and using simple software methods. A wireless sensor …

Sensing With The Motor Cortex, Nicholas G. Hatsopoulos, Aaron J. Suminski

Biomedical Engineering Faculty Research and Publications

The primary motor cortex is a critical node in the network of brain regions responsible for voluntary motor behavior. It has been less appreciated, however, that the motor cortex exhibits sensory responses in a variety of modalities including vision and somatosensation. We review current work that emphasizes the heterogeneity in sensorimotor responses in the motor cortex and focus on its implications for cortical control of movement as well as for brain-machine interface development.

A Test Method For Optimal Micro-Screen Drum Filter Selection, Eoin Dolan, Ronan Oliver, Niall Murphy, Michael O'Hehir

Other resources

In order to meet increasing demand for seafood worldwide Recirculation Aquaculture Systems (RAS) are frequently used. These systems are susceptible to contamination by waste matter including faecal material in the water. It is imperative that this material is removed from the system. The maintenance of good water quality is a pre-requisite to the success of the operation. Negligence in this area will adversely affect animal growth rates and also the economic performance of the system.

Micro-screen drum filters are a popular solution for the removal of this material (Cripps, Simon J. and Bergheim, Asbjørn., 2000). These screens are nominally rated …

Bs News November/December

Building Services Engineering

No abstract provided.

History Of The Biological Systems Engineering Program In Nebraska, University Of Nebraska-Lincoln, William E. Splinter

Department of Agricultural and Biological Systems Engineering: Faculty Publications

The Farm Machinery/Agricultural Engineering/Biological Systems Engineering program current and former faculty members at the University of Nebraska, as demonstrated here, has made a statewide, national, and worldwide impact on the efficient production of food. The quality of this recognition is evidenced best by peer professionals through recognized ASABE awards received by Nebraska alumni or professors. Since its inception in 1909 and until 2010, there have been 10 national presidents, 19 gold medal recipients and 33 named national award recipients. Currently there are 31 ASABE Fellows and two members of the National Academy of Engineering. This national recognition comes as a …