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Articles 5791 - 5820 of 39346
Full-Text Articles in Entire DC Network
Variation In Establishment Success For American Mistletoe [Phoradendron Leucarpum (Raf.) Reveal & M.C. Johnst. (Viscaceae)] Appears Most Likely To Predict Its Distribution In Virginia And North Carolina, United States, Nicholas P. Flanders, Christopher P. Randle, Eric L. Walters, Lytton J. Musselman
Variation In Establishment Success For American Mistletoe [Phoradendron Leucarpum (Raf.) Reveal & M.C. Johnst. (Viscaceae)] Appears Most Likely To Predict Its Distribution In Virginia And North Carolina, United States, Nicholas P. Flanders, Christopher P. Randle, Eric L. Walters, Lytton J. Musselman
Biological Sciences Faculty Publications
Dispersal limitation and variation in habitat suitability may determine an association of American mistletoe [Phoradendron leucarpum (Raf.) Reveal & M.C. Johnst. (Viscaceae)] with forested wetlands in Virginia and North Carolina, United States. Here, we first tested the alternative hypothesis that variation in host availability drives this habitat relationship. We used a generalized linear model to show a positive effect of forested wetland habitat on American mistletoe occurrence after accounting for both variation in host availability and differences among regions in host use. We then used seed sowing experiments to quantify how light availability and flood regime determine the viability …
Pancreatic Ductal Adenocarcinoma And New Treatments In Development, Melissa J. Moisan
Pancreatic Ductal Adenocarcinoma And New Treatments In Development, Melissa J. Moisan
Biology and Microbiology Graduate Students Plan B Research Projects
Pancreatic ductal adenocarcinoma (PDAC) is the most frequently mutated (95%) 5exocrine pancreatic cancers. Patients with PDAC are also the least likely to survive more than 5 years with only 8% overall survivability. The median survival for patients with distant metastasis is less than one year. Most pancreatic ductal adenocarcinoma occurs in the pancreatic head, and the remainder can be found within the body (5% to 15%) or tail (10% to 15%) (14). This extremely aggressive cancer has an increasingly large metastatic dissemination rate to surrounding organs such as the liver, lung, and peritoneum, or can be seen as distant metastases …
Is Growth Hormone The Fountain Of Youth?, David Youlus
Is Growth Hormone The Fountain Of Youth?, David Youlus
The Science Journal of the Lander College of Arts and Sciences
Finding the cure for aging has been a sought-after quest for as long as the world has existed. Growth hormone has been shown as a possible treatment to negate the phenotypic effects of aging. Growth hormone is released from the adenohypophysis in response to sleep, exercise and stress. This in turn stimulates insulin-like growth factor-1 (IGF-1) secretion from the liver. Growth hormone circulation decreases in volume during aging. Studies on growth hormone therapy have indicated youth-like benefits, such as the reversal of sarcopenia, improved cognitive function, and boosted immunity. However, creating an imbalance of growth hormone and insulin-like factor-1 also …
The Evaluation Of The Efficacy And Safety Of Different Methods Of Myopia Control, Chaya Feuchtwanger
The Evaluation Of The Efficacy And Safety Of Different Methods Of Myopia Control, Chaya Feuchtwanger
The Science Journal of the Lander College of Arts and Sciences
Myopia is the leading cause of preventable blindness in East Asia and has a rising global prevalence. If no treatment is done to curb myopic progression, the eye will continue to grow leading to high refractive errors. A higher prescription leads to an increased risk of developing sight-threatening diseases that can lead to irreversible blindness later in life. The discovery of a treatment that slows or even stops myopia from progressing is increasingly important with many studies being conducted worldwide. Currently, the most effective forms of myopia control are atropine eye drops and specialty contact lenses, with new studies exploring …
Epilepsy And Treatment Resistance, Eva Kowalsky
Epilepsy And Treatment Resistance, Eva Kowalsky
The Science Journal of the Lander College of Arts and Sciences
Epilepsy is one of the most common debilitating neurological conditions. Individuals with epilepsy experience frequent seizures. Seizures are caused by hyperexcitable and hyper-synchronized neurons. Anti-seizure medications typically work to normalize the electrical activity in the brain. Many epileptic disorders are caused by genetic mutations, most of which cause mutations in ion channel mechanics. 30% of individuals with epilepsy do not respond to classic anti-seizure medications. A combination of factors typically contributes to treatment resistance. Individuals with drug-resistant epilepsy must turn to novel approaches for seizure relief. These approaches include following a ketogenic diet, using CBD products, utilizing a neurostimulator device, …
Stroke Recovery, Laya Brodie
Stroke Recovery, Laya Brodie
The Science Journal of the Lander College of Arts and Sciences
For years the brain was thought not to be regenerative, yet research has highlighted the role of neuroplasticity, neurogenesis, and deep brain stimulation in promoting brain recovery and enhancing stroke rehabilitation. Neuroplasticity is the brain’s ability to reorganize neural pathways in response to environmental or structural changes. Stroke recovery is possible due to the plasticity of the brain; the brain can create new neural pathways and neurons. Traditionally it was believed that humans were limited to generating new neurons in the brain, recent studies have shown that neurogenesis occurs throughout adulthood, particularly in the hippocampus, a region as- sociated with …
The Effects Of Nausea And Vomiting On Mother And Child, Mayane Bensoussan
The Effects Of Nausea And Vomiting On Mother And Child, Mayane Bensoussan
The Science Journal of the Lander College of Arts and Sciences
Nausea and vomiting are common side effects that can occur during pregnancy. On one hand, it can lead to its severe form called hyperemesis gravidarum, which can lead to hospitalization for electrolyte imbalances, dehydration, muscle weakness, or arrhythmias. On the other hand, nausea and vomiting may be an indication of a statistically healthier fetus. Benefits of maternal nausea and emesis to the developing fetus include improved neural development, decreased risk for congenital heart defects, and decreased incidence of miscarriages. Additionally, benefits to the mother include decreased risk for lung, cervical, and rectal cancer. The mothers also had an overall decreased …
Immunotherapy For The Treatment Of Pediatric Cancers: What Is The Best Option?, Miriam Raitport
Immunotherapy For The Treatment Of Pediatric Cancers: What Is The Best Option?, Miriam Raitport
The Science Journal of the Lander College of Arts and Sciences
Cancer is the leading cause of death by disease in the pediatric population in the United States. The current standard of care for treating pediatric cancer is traditional: chemotherapy, radiation, and surgery. However, these conventional approaches have many unpleasant short-term and long-term side effects and do not offer a genuine cure. Immunotherapy as a cancer treatment is a new approach that has produced very promising results in the pediatric population. Four leading therapies for pediatric cancers are CAR T-cell therapy, oncolytic virotherapy, monoclonal antibody treatments, and cancer vaccines. Some of the therapies have more promising results than others, and different …
What Is The Best Treatment For Osteoporosis?, Joshua Sodden
What Is The Best Treatment For Osteoporosis?, Joshua Sodden
The Science Journal of the Lander College of Arts and Sciences
Osteoporosis is a bone disease that leads to frail bones, caused by osteoclasts destroying more bone than osteoblasts can create. It is more common among elderly people due to a lack of growth factors that promote osteoblasts. Estrogen plays a very important role in bone homeostasis of women; therefore post-menopausal women are most commonly affected because of their lack of estrogen production. Currently the FDA has approved eleven different drug treatments for osteoporosis. These treatments include anabolic treatments such as parathyroid hormone and anti-sclerostin, as well as catabolic treatments which include bisphosphonates, estrogen hormone, SERMs and anti-RANKL. This paper describes …
Effects Of Microdosing With Psilocybin Mushrooms, Chavivah Davis
Effects Of Microdosing With Psilocybin Mushrooms, Chavivah Davis
The Science Journal of the Lander College of Arts and Sciences
Microdosing with psilocybin, a psychoactive compound found in certain species of mushrooms, has gained popularity in recent years as a means of enhancing mood, cognition, and creativity without inducing the full-blown psychedelic experience. There are many potential benefits associated with microdosing with psilocybin. Although studies do show many positive effects of microdosing with psilocybin, long-term research is required to make a conclusive statement regarding this topic. Furthermore, there are risks and concerns involved that need to be considered, including the illegality of psilocybin and the lack of research. This paper will review the available literature on microdosing with psilocybin. It …
Full Issue: Volume 17, Number 1, Fall 2023
Full Issue: Volume 17, Number 1, Fall 2023
The Science Journal of the Lander College of Arts and Sciences
Complete .pdf file of Volume 17, Number 1 of The Science Journal of the Lander College of Arts and Sciences. Published Fall 2023.
Epinephrine And Cardiac Arrest: The Catch-22, Shaina Friedman
Epinephrine And Cardiac Arrest: The Catch-22, Shaina Friedman
The Science Journal of the Lander College of Arts and Sciences
Epinephrine has been a standard of care treatment for cardiac arrest for the last century; however, the use of epinephrine began without a significant amount of research. In recent years, many have started to question whether epinephrine is an appropriate treatment for cardiac arrest. While epinephrine causes vasoconstriction of the blood vessels and directs much-needed blood flow to the heart, it has also been shown to harm the microvessels of the brain, causing ischemia and neurological damage. Many trials, studies, and surveys were conducted to determine the correct course of action involving the use of epinephrine during cardiac arrest. Additional …
The Impact Of Gestational Diabetes On The Offspring, Deborah Daniel
The Impact Of Gestational Diabetes On The Offspring, Deborah Daniel
The Science Journal of the Lander College of Arts and Sciences
A prevalent pregnancy condition known as gestational diabetes mellitus (GDM) is characterized by elevated blood sugar levels while pregnant. GDM poses implications for both maternal and fetal health. Through extensive research, this paper provides a thorough analysis of the potential effects of GDM on the offspring. According to studies, GDM can negatively impact fetal growth and development, increasing the risk of macrosomia, shoulder dystocia, and neonatal hypoglycemia. Additionally, type 2 diabetes, obesity, and hypertension are among the metabolic and cardiovascular disorders that infants born to women with GDM are more likely to experience as adults. These long-term effects may be …
Immunosuppression After Cardiac Transplantation: What Is The Best Approach?, Sara Batya Friedman
Immunosuppression After Cardiac Transplantation: What Is The Best Approach?, Sara Batya Friedman
The Science Journal of the Lander College of Arts and Sciences
Cardiac transplantation is a life-saving procedure for patients in end-stage heart failure. Since the first heart transplant in 1967, survival rates have steadily increased. This is largely on account of advancing immunosuppressive therapies, although immuno- suppression protocol still varies greatly among transplant centers, with no ideal regimen to follow. A fine balance lies between under-immunosuppression leading to rejection, and over-immunosuppression causing complications, toxicity, and adverse effects. Some successful therapies include steroids, lymphocyte proliferation inhibitors, and calcineurin inhibitors. Much of the available evidence as to which regimens have been successful is from retrospective analyses, indicating the need for more studies to …
The Impact Of Maternal Health On Breastfeeding Duration, Yael Weinberg
The Impact Of Maternal Health On Breastfeeding Duration, Yael Weinberg
The Science Journal of the Lander College of Arts and Sciences
The mechanism of breastfeeding is a complex biological process beginning with hormone production from the pituitary gland and ending with the ejection of milk from the breasts. Mothers are recommended to breastfeed exclusively for six months and then continue for another six with the addition of solid food. However, despite the countless health benefits associated with lengthened breastfeeding for both mother and infant, many women dismiss this recommendation. This paper aims to research the aspects of maternal health that can derail the recommended duration of breastfeeding, focusing on emotional health, nutritional intake, and various diseases or surgeries. It is found …
Do The Benefits Of Growth Hormone Outweigh The Risks?, Michael D. Goodstein
Do The Benefits Of Growth Hormone Outweigh The Risks?, Michael D. Goodstein
The Science Journal of the Lander College of Arts and Sciences
Growth hormone treatment was introduced in the 1950s to confront growth hormone deficiency and metabolic irregularities. In 2003, however, the FDA approved growth hormone treatment for patients with abnormal growth rates unlinked to growth hormone deficiency. The treatment has become largely available to the general public, making the safety of growth hormone treatment an extremely important subject. This paper clarifies the benefits and efficacy of growth hormone treatment and analyzes the potential associated risks, including cancer and diabetes.
Redescription Of Adults And First Description Of The Larva Of Haemaphysalis (Rhipistoma) Adleri Feldman-Muhsam, 1951 (Acari: Ixodidae), Parasite Of Carnivorans In Western Asia, Cole Anderson
Honors College Theses
The adult ticks of Haemaphysalis (Rhipistoma) adleri Feldman-Muhsam, 1951 (Acari: Ixodidae) are redescribed and the larva of this species is described for the first time here. The adults of H. adleri that we studied were collected from various canid, felid and hyaenid carnivorans (Carnivora: Canidae, Felidae, Hyaenidae) as well as a hedgehog (Erinaceomorpha: Erinaceidae) in Iraq, Israel and West Bank. The males, females and larvae of H. adleri can be differentiated from Haemaphysalis (Rhipistoma) species occurring in the Palearctic portion of West Asia and Egypt as well those in the H. asiatica subgroup by the length of idiosomal …
Potential Repercussions Of Offshore Wind Energy Development In The Northeast United States For The Atlantic Surfclam Survey And Population Assessment, Sarah Borsetti, Daphne M. Munroe, Andrew M. Scheld, Eric N. Powell, John M. Klinck, Eileen E. Hofmann
Potential Repercussions Of Offshore Wind Energy Development In The Northeast United States For The Atlantic Surfclam Survey And Population Assessment, Sarah Borsetti, Daphne M. Munroe, Andrew M. Scheld, Eric N. Powell, John M. Klinck, Eileen E. Hofmann
CCPO Publications
The Atlantic surfclam Spisula solidissima fishery, which spans the U.S. Northeast continental shelf, is among the most exposed to offshore wind energy development impacts because of the overlap of fishing grounds with wind energy lease areas, the hydraulic dredges used by the fishing vessels, and the location of vessel home ports relative to the fishing grounds. The Atlantic surfclam federal assessment survey is conducted using a commercial fishing vessel in locations that overlap with the offshore wind energy development. Once wind energy turbines, cables, and scour protection are installed, survey operations within wind energy lease areas may be curtailed or …
Lake Huron Microbial Mats: A Novel Anagnostidinema Species, A Cyanobacteria-Specific It's Motif Slicer, & A Multi-Marker Community Analysis, Callahan Mcgovern
Lake Huron Microbial Mats: A Novel Anagnostidinema Species, A Cyanobacteria-Specific It's Motif Slicer, & A Multi-Marker Community Analysis, Callahan Mcgovern
UNF Graduate Theses and Dissertations
A region of Lake Huron near Alpena, Michigan (U.S.A) includes karstic sinkholes with oxygen-poor, sulfur-rich ground water that contain vibrant microbial mats resembling life in early Earth’s shallow seas. We sought to document some of this unique ? diversity including the cyanobacteria, heterotrophic bacteria, and diatoms. Using culture-based investigations, we recovered strains of a novel cyanobacterium, Anagnostidinema visiae, and by employing a polyphasic approach we described this novel species from the Middle Island Sinkhole. In the processes of characterizing this novel species, the challenges of cyanobacterial systematics became evident. This led us to create a bioinformatics tool to help in …
Otoliths Through Time: A Multidecadal Characterization Of Fish Otoliths In A Changing Climate, Jordan M. Waldron
Otoliths Through Time: A Multidecadal Characterization Of Fish Otoliths In A Changing Climate, Jordan M. Waldron
UNF Graduate Theses and Dissertations
There is a lack of research describing how widespread environmental changes in marine ecosystems affect wild adult teleost otoliths, limiting our ability to understand the impacts that alterations to otoliths can have on fish physiology and ecology. In this study, morphological and microstructural changes in wild adult fish otoliths were traced over 3 decades among species common in Tampa Bay, Florida – red drum Sciaenops ocellatus and common snook Centropomus undecimalis. Optical microscopy and scanning electron microscopy were used to characterize otolith morphology and microstructure, respectively, to then pair with fluctuations in environmental variables – water temperature, pH, dissolved …
The Angiogenic Potential Of Ph-Neutral Borophosphate Bioactive Glasses, Bradley A. Bromet, Nathaniel P. Blackwell, Nada Abokefa, Parker Freudenberger, Rebekah L. Blatt, Richard K. Brow, Julie A. Semon
The Angiogenic Potential Of Ph-Neutral Borophosphate Bioactive Glasses, Bradley A. Bromet, Nathaniel P. Blackwell, Nada Abokefa, Parker Freudenberger, Rebekah L. Blatt, Richard K. Brow, Julie A. Semon
Materials Science and Engineering Faculty Research & Creative Works
Borate bioactive glasses have gained attention in recent years due to their therapeutic and regenerative effects in vivo. However, borate bioactive glasses release alkaline ions, increasing the local pH and creating a toxic environment for cell culture studies. A partial compositional substitution of phosphate for borate can create a pH-neutral glass that does not significantly affect the local pH while still releasing therapeutic ions. In the present study, a series of Na-Ca-borophosphate bioactive glasses with different borate-to-phosphate ratios was evaluated in vitro and in vivo for cytotoxicity and angiogenic effects. Compared to more basic borate glasses, the pH-neutral glasses supported …
Genome Sequence Of Subcluster L3 Mycobacterium Smegmatis Mc2155 Phage Duncansleg, Megan Cevasco, Kaitlynn Burbage, Connor Hadwin, Edenborough Hibionada, Kirsten Presnell, Daniel Williams
Genome Sequence Of Subcluster L3 Mycobacterium Smegmatis Mc2155 Phage Duncansleg, Megan Cevasco, Kaitlynn Burbage, Connor Hadwin, Edenborough Hibionada, Kirsten Presnell, Daniel Williams
Biology
Bacteriophage DuncansLeg is a siphovirius isolated in 2021 from soil on the Coastal Carolina University campus in Conway, South Carolina, using the host Mycobacterium smegmatis mc2155. DuncansLeg has a 75,593-bp circular genome that contains 126 predicted protein-coding genes and 10 tRNA genes. DuncansLeg is assigned to actinobacteriophage cluster L3.
Genome Sequences Of Six Cluster Ct And Two Cluster Dj Bacteriophages That Infect Gordonia Rubripertincta, Xavier F. Rodriguez, Daniel C. Williams, Catherine P. Chia
Genome Sequences Of Six Cluster Ct And Two Cluster Dj Bacteriophages That Infect Gordonia Rubripertincta, Xavier F. Rodriguez, Daniel C. Williams, Catherine P. Chia
Biology
We report the genome sequences of eight bacteriophages isolated using Gordonia rubripertincta NRRL B-16540-SEA. Based on gene content similarity to phages in the Actinobacteriophage database, six of the phages are assigned to phage cluster CT while two are assigned to cluster DJ.
Pharmaceuticals From Natural Products: The Utility Of The Phylogeny, Shaimaa Magdy Saad
Pharmaceuticals From Natural Products: The Utility Of The Phylogeny, Shaimaa Magdy Saad
Selected Full-Text Master Theses 2021-
About 60% of approved drugs during the last 30 years are either directly or indirectly from natural products. Previous studies have shown that the phylogeny has predictive utility in drug discovery. In this study the pharmacological applications of various naturally-derived drugs were mapped on the phylogeny reconstructed from DNA sequences of the source organisms to decipher phylogenetic patterns that may facilitate drug discovery. A multi-step approach was employed starting with a literature search to compile a comprehensive list of pharmaceutical drugs derived from natural sources. A phylogeny was reconstructed from the source organisms and their pharmacological uses mapped on the …
Bat Activity And Insect Biomass On Mcconnell Airforce Base Compared To Surrounding Wichita Parks, Michaela Sielaff
Bat Activity And Insect Biomass On Mcconnell Airforce Base Compared To Surrounding Wichita Parks, Michaela Sielaff
Master's Theses or Doctor of Nursing Practice
Bats are bioindicators of the communities to which they belong, giving researchers insight into the overall health of those ecosystems. Bats are also very adaptable and are capable of tolerating urbanization. Some species, such as Lasiurus borealis and Lasionycteris noctivagans may even benefit from adjacent industrial and commercial land use, although this is not the case for all bat species. In 2021, we began acoustic and mist net surveys of bats at McConnell Air Force Base (MAFB, or “base”) in Wichita, KS. However, no bats were captured or seen during mist net surveys, although some were detected acoustically over a …
Relationship Between Bats And Prairie-Dog (Cynomys Ludovicianus) Colonies In Western Kansas, Mario N. Rodriguez
Relationship Between Bats And Prairie-Dog (Cynomys Ludovicianus) Colonies In Western Kansas, Mario N. Rodriguez
Master's Theses or Doctor of Nursing Practice
Although it is known that prairie dog colonies can increase biodiversity in the areas surrounding them, there is extraordinarily little known about the relationship between bats and black-tailed prairie dogs (Cynomys ludovicianus). In a recent study from the Front Range of Colorado, several bat species were found to be consistently flying around prairie dog colonies, presumably foraging due to increased insect diversity and abundance. Despite the importance of prairie dogs to the ecosystem, prairie dog colonies are usually eradicated due to the perception that they adversely impact cattle grazing. If insectivorous bats are attracted to prairie dog colonies …
Methylation Patterns Across Tissue Type And Time In Peromyscus Leucopus: A Targeted Museum Study, Loryn Smith
Methylation Patterns Across Tissue Type And Time In Peromyscus Leucopus: A Targeted Museum Study, Loryn Smith
Master's Theses or Doctor of Nursing Practice
Museum specimens are a vital data source for many types of studies. One relatively new use includes studying methylation patterns. Methylation patterns are a form of epigenetics or how gene expression changes without alteration of the genetic code. These patterns have been examined in many mammals. However, the focus has previously been on overall epigenetic patterns. Few studies have investigated whether methylation patterns differ across tissue types, time, or preservation method. In this study, I compared methylation patterns in muscle, liver, toe pads, and nasal bones from Peromyscus leucopus (white-footed mouse) museum specimens collected in 2022, 2018, 2014, and 2008 …
Conservation Status Of The Chihuahuan Green Toad, Anaxyrus Debilis, In Western Kansas Range, Mackenzie Reh
Conservation Status Of The Chihuahuan Green Toad, Anaxyrus Debilis, In Western Kansas Range, Mackenzie Reh
Master's Theses or Doctor of Nursing Practice
Amphibians remain an important model organism closely associated with environmental conditions and ecological processes. They are considered critical bioindicators of the relative health of ecosystems providing insights into levels of pollution, such as agricultural and industrial runoff, effects of UVB increases, ecosystem service functionality and much more (Rohman et al. 2021). Amphibians are an essential food source to organisms at higher trophic levels and to humans in developing countries (Schleich et al. 1996). Amphibians also provide pest control for agricultural and urban landscapes (Warkentin et al. 2009). Amphibians provide novel medicinal treatments for a wide variety of human ailments and …
Grassland Nesting Birds And Visual Obstruction Measurements In Western Kansas On Smoky Valley Ranch, Connor J. Champney
Grassland Nesting Birds And Visual Obstruction Measurements In Western Kansas On Smoky Valley Ranch, Connor J. Champney
Master's Theses or Doctor of Nursing Practice
North American grassland declines and increasing changes in land use patterns have revived the importance of studying grasslands and their inhabitants. Grassland breeding bird populations are declining rapidly, and conservation efforts are ramping up. Smoky Valley Ranch (SVR) owned by The Nature Conservancy (TNC) is in Logan County, Kansas. Surrounding private land is characteristically comprised of row crops, livestock agriculture, Conservation Reserve Program (CRP), and a few patches of native and restored prairie. The study of obligate grassland birds utilizing this area during the breeding season is essential to the proliferation of grassland bird nesting habitat in western, Kansas. The …
Habitat Associations And Fine-Scale Movements Of The Red-Spotted Toad (Anaxyrus Punctatus) In Kansas And The Efficacy Of Remote Telemetry For Monitoring Small-Scale Movements, Elisabeth Russell
Master's Theses or Doctor of Nursing Practice
As climate change progresses, arid-adapted anurans might be particularly susceptible to population declines because of their reliance on ephemeral pools for successful reproduction. Because arid-adapted anurans are difficult to study due to short active seasons and cryptic lifestyles, little is known about their habitat preferences. One such arid-adapted species is the Red-Spotted Toad (Anaxyrus punctatus; RST), a Kansas Species in Need of Conservation. Since this designation in 1987, little research has been conducted to understand their conservation needs. During the summers of 2021 and 2022, RST surveys were conducted both near areas where the species has historically been …