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Articles 931 - 960 of 20606
Full-Text Articles in Entire DC Network
General Biology 2 Laboratory Manual: In Person Edition, Dmitry Y. Brogun, Azure N. Faucette, Farshad Tamari, Kristin Polizzotto
General Biology 2 Laboratory Manual: In Person Edition, Dmitry Y. Brogun, Azure N. Faucette, Farshad Tamari, Kristin Polizzotto
Open Educational Resources
The completed project is an in-person teaching version of the General Biology II OER (Open Educational Resource) lab manual. This lab manual was initially written by the four of us during the pandemic when all courses were online, but it is now has been adapted for in-person lab activities. We also ensured it aligns with UDL (Universal Design for Learning) and accessibility principles. This adaptation aims to make the lab manual suitable for traditional classroom settings while incorporating diverse teaching practices to accommodate diverse learners.
Comprehensive Review On The Application Of Bio-Immunoinformatics In The Development Of Highly Ef-Fective New Candidate Vaccines Against Tuberculosis, Ahyar Ahmad, Andriansjah Rukmana, Miski A. Khairinisa, Dian A. E. Pitaloka, Rosana Agus, Rusdina B. Ladju, Tarwadi Ahmad, Astutiati Nurhasanah, Carina C. D. Joe, Muhammad N. Massi, Harningsih Karim, Irda Handayani, Siti Roszilawati Binti Ramli
Comprehensive Review On The Application Of Bio-Immunoinformatics In The Development Of Highly Ef-Fective New Candidate Vaccines Against Tuberculosis, Ahyar Ahmad, Andriansjah Rukmana, Miski A. Khairinisa, Dian A. E. Pitaloka, Rosana Agus, Rusdina B. Ladju, Tarwadi Ahmad, Astutiati Nurhasanah, Carina C. D. Joe, Muhammad N. Massi, Harningsih Karim, Irda Handayani, Siti Roszilawati Binti Ramli
Karbala International Journal of Modern Science
Tuberculosis (TB) remains a significant public health challenge worldwide. Currently, Bacillus Calmette-Guerin (BCG) is the only vaccine available for TB prophylaxis. However, the efficacy of the BCG vaccine against adult pulmonary TB is considered inconsistent. This condition encourages researchers to look for more effective options, such as subunit vaccines. This condition requires the development of a more effective subunit vaccine to protect active TB in productive and adult ages. There is an urgent need for more effective vaccines, as the Bacillus Calmette-Guérin (BCG) vaccine currently available has inconsistent efficacy and is only partially effective in adults. Bio-immunoinformatics, an interdisciplinary field …
A Role For The Actin Cytoskeleton And Plastin-3 In Osteoblast Mineralization And Mechanosensation, Samantha Meagan Chin
A Role For The Actin Cytoskeleton And Plastin-3 In Osteoblast Mineralization And Mechanosensation, Samantha Meagan Chin
Arts & Sciences Graduate Student Theses and Dissertations
The great diversity in actin network architectures and dynamics is exploited by cells to drive fundamental biological processes including cell migration, intracellular trafficking, and cell division. One such system that relies on the actin cytoskeleton to fulfill its physiological function are osteoblasts, which are mesenchymal lineage bone cells that promote bone formation through depositing a collagen scaffold and subsequently promoting mineralization of this matrix. A number of factors are known to drive osteogenic differentiation of pre-osteoblast cells including extracellular matrix cues such as substrate stiffness, which are primarily detected via mechanosensitive machinery linked to the actin cytoskeleton. Disruptions to β-actin, …
Pituitary Adenylate Cyclase Activating Polypeptide And Its Receptor As Novel Therapeutic Targets For Opioid Induced Hyperalgesia, Elizaveta Mangutov
Pituitary Adenylate Cyclase Activating Polypeptide And Its Receptor As Novel Therapeutic Targets For Opioid Induced Hyperalgesia, Elizaveta Mangutov
Arts & Sciences Graduate Student Theses and Dissertations
Opioids are commonly prescribed for the treatment of pain and headache disorders. However, chronic opioid use can result in a paradoxical increased sensitivity to pain as well as an extension of pain area known as opioid-induced hyperalgesia (OIH). One field OIH has been clearly identified is migraine, known as medication overuse headache (MOH). While opioids may provide acute relief, chronic use results in increased migraine pain severity and progression of migraine from an episodic to chronic state. The primary treatment is opioid cessation, which is difficult to implement as patients are reluctant to stop treatment they believe is helping them, …
Pituitary Adenylate Cyclase Activating Polypeptide And Its Receptor As Novel Therapeutic Targets For Opioid Induced Hyperalgesia, Elizaveta Mangutov
Pituitary Adenylate Cyclase Activating Polypeptide And Its Receptor As Novel Therapeutic Targets For Opioid Induced Hyperalgesia, Elizaveta Mangutov
Arts & Sciences Graduate Student Theses and Dissertations
Opioids are commonly prescribed for the treatment of pain and headache disorders. However, chronic opioid use can result in a paradoxical increased sensitivity to pain as well as an extension of pain area known as opioid-induced hyperalgesia (OIH). One field OIH has been clearly identified is migraine, known as medication overuse headache (MOH). While opioids may provide acute relief, chronic use results in increased migraine pain severity and progression of migraine from an episodic to chronic state. The primary treatment is opioid cessation, which is difficult to implement as patients are reluctant to stop treatment they believe is helping them, …
A Role For The Actin Cytoskeleton And Plastin-3 In Osteoblast Mineralization And Mechanosensation, Samantha Meagan Chin
A Role For The Actin Cytoskeleton And Plastin-3 In Osteoblast Mineralization And Mechanosensation, Samantha Meagan Chin
Arts & Sciences Graduate Student Theses and Dissertations
The great diversity in actin network architectures and dynamics is exploited by cells to drive fundamental biological processes including cell migration, intracellular trafficking, and cell division. One such system that relies on the actin cytoskeleton to fulfill its physiological function are osteoblasts, which are mesenchymal lineage bone cells that promote bone formation through depositing a collagen scaffold and subsequently promoting mineralization of this matrix. A number of factors are known to drive osteogenic differentiation of pre-osteoblast cells including extracellular matrix cues such as substrate stiffness, which are primarily detected via mechanosensitive machinery linked to the actin cytoskeleton. Disruptions to β-actin, …
Assessing The Biological Impacts And Health Risks Of Uv Radiation In The Context Of Sustainable Development Goals: Review, Ruaa H. Abbas, Lina M. Shaker
Assessing The Biological Impacts And Health Risks Of Uv Radiation In The Context Of Sustainable Development Goals: Review, Ruaa H. Abbas, Lina M. Shaker
AUIQ Complementary Biological System
Ultraviolet (UV) radiation, while essential for certain biological processes, presents significant risks to human health and ecosystems. Increased UV exposure, driven by ozone depletion and climate change, heightens threats such as DNA damage, skin cancer, immune suppression, and eye disorders, directly aligning with Sustainable Development Goal (SDG) 3: Good Health and Well-being. Additionally, UV radiation disrupts marine and terrestrial ecosystems, impacting biodiversity and productivity, relevant to SDGs 14 and 15. This review evaluates the health and environmental impacts of UV radiation and highlights recent advancements in UV monitoring technology. Key findings reveal substantial evidence linking UV exposure to accelerated skin …
Nucleoredoxin Regulates Wnt Signaling During Pituitary Stem Cell Differentiation, Michelle L. Brinkmeier, Leonard Y M Cheung, Sean P. O'Connell, Diana K. Gutierrez, Eve C. Rhoads, Sally A. Camper, Shannon W. Davis
Nucleoredoxin Regulates Wnt Signaling During Pituitary Stem Cell Differentiation, Michelle L. Brinkmeier, Leonard Y M Cheung, Sean P. O'Connell, Diana K. Gutierrez, Eve C. Rhoads, Sally A. Camper, Shannon W. Davis
Faculty Publications
Nucleoredoxin (Nxn) encodes a multi-functional enzyme with oxidoreductase activity that regulates many different signaling pathways and cellular processes in a redox-dependent manner. Rare NXN mutations are reported in individuals with recessive Robinow syndrome, which involves mesomelic skeletal dysplasia, short stature, craniofacial dysmorphisms, and incompletely penetrant heart and palate defects. Here we report that Nxn is expressed in the ventral diencephalon and developing pituitary gland, and that Nxn deficient mice have pituitary dysmorphology and craniofacial abnormalities that include defects in the skull base and cleft palate. Nxn mutant mice exhibit reduced WNT signaling and reduced differentiation of pituitary stem …
Disruption Of G3bp1 Granules Promotes Mammalian Cns And Pns Axon Regeneration, Pabitra K. Sahoo, Manasi Agrawal, Nicholas Hanovice, Patricia J. Ward, Meghal Desai, Terika P. Smith, Hao Min Sima, Jennifer N. Dulin, Lauren S. Vaughn, Mark H. Tuszynski, Kristy Welshhans, Larry I. Benowitz, Arthur W. English, John D. Houle, Jeffery L. Twiss
Disruption Of G3bp1 Granules Promotes Mammalian Cns And Pns Axon Regeneration, Pabitra K. Sahoo, Manasi Agrawal, Nicholas Hanovice, Patricia J. Ward, Meghal Desai, Terika P. Smith, Hao Min Sima, Jennifer N. Dulin, Lauren S. Vaughn, Mark H. Tuszynski, Kristy Welshhans, Larry I. Benowitz, Arthur W. English, John D. Houle, Jeffery L. Twiss
Faculty Publications
Depletion or inhibition of core stress granule proteins, G3BP1 in mammals and TIAR-2 in Caenorhabditis elegans, increases the growth of spontaneously regenerating axons. Inhibition of G3BP1 by expression of its acidic or “B-domain” accelerates axon regeneration after nerve injury, bringing a potential therapeutic strategy for peripheral nerve repair. Here, we asked whether G3BP1 inhibition is a viable strategy to promote regeneration in injured mammalian central nervous system (CNS) where axons do not regenerate spontaneously. G3BP1 B-domain expression was found to promote axon regeneration in the transected spinal cord provided with a permissive peripheral nerve graft (PNG) as well as in …
Disruption Of G3bp1 Granules Promotes Mammalian Cns And Pns Axon Regeneration, Pabitra K. Sahoo, Manasi Agrawal, Nicholas Hanovice, Patricia J. Ward, Meghal Desai, Terika P. Smith, Haomin Sima, Jennifer N. Dulin, Lauren S. Vaughn, Mark H. Tuszynski, Kristy Welshhans, Larry I. Benowitz, Arthur W. English, John D. Houle, Jeffery L. Twiss
Disruption Of G3bp1 Granules Promotes Mammalian Cns And Pns Axon Regeneration, Pabitra K. Sahoo, Manasi Agrawal, Nicholas Hanovice, Patricia J. Ward, Meghal Desai, Terika P. Smith, Haomin Sima, Jennifer N. Dulin, Lauren S. Vaughn, Mark H. Tuszynski, Kristy Welshhans, Larry I. Benowitz, Arthur W. English, John D. Houle, Jeffery L. Twiss
Faculty Publications
Depletion or inhibition of core stress granule proteins, G3BP1 in mammals and TIAR-2 in Caenorhabditis elegans, increases the growth of spontaneously regenerating axons. Inhibition of G3BP1 by expression of its acidic or “B-domain” accelerates axon regeneration after nerve injury, bringing a potential therapeutic strategy for peripheral nerve repair. Here, we asked whether G3BP1 inhibition is a viable strategy to promote regeneration in injured mammalian central nervous system (CNS) where axons do not regenerate spontaneously. G3BP1 B-domain expression was found to promote axon regeneration in the transected spinal cord provided with a permissive peripheral nerve graft (PNG) as well as …
Cryptosporidium Virus Integration Into The Host Cells, Alyssa Genaro
Cryptosporidium Virus Integration Into The Host Cells, Alyssa Genaro
Biochemistry and Molecular Biology
Cryptosporidiosis is a disease that affects a large amount of people and having a high mortality rate for those that are immunocompromised such as the elderly and infants. The disease is linked to a parasite called Cryptosporidium parvum, which is mostly known to infect cattle and other mammals such as mice and humans. The parasite contains a double stranded RNA virus, the Cryspovirus (CSpV1) that has a non-enveloped icosahedral capsid, with a T=2* icosahedral symmetry. Little is known is known about the contribution of CSpV1 to the disease; In this study we show that infection of an immunocompromised mouse model …
A High-Lipid Diet Leads To Greater Pathology And Lower Tolerance During Infection, Weston Gerald Perrine, Erin Sauer, Ashley C. Love, Ashley Morris, Johnathan Novotny, Sarah Durant
A High-Lipid Diet Leads To Greater Pathology And Lower Tolerance During Infection, Weston Gerald Perrine, Erin Sauer, Ashley C. Love, Ashley Morris, Johnathan Novotny, Sarah Durant
Biological Sciences Faculty Publications and Presentations
Altered food landscapes contribute importantly to wildlife disease dynamics and may play a critical role in host heterogeneity in disease outcomes through changes in host diet composition. We explored the effects of dietary macronutrient composition on disease pathology and feeding behavior of canaries (Serinus canaria domestica) infected with Mycoplasma gallisepticum (MG). In the first experiment, we provided canaries with isocaloric diets composed of identical ingredients that varied in macronutrient content (high protein or high lipid) then MG- or sham-inoculated birds. In the second experiment, we offered both diets to canaries before and after MG or sham inoculation. In experiment one, …
Evolution Of Mate Guarding Intensity In Crickets As A Possible Adaptation To Sexual Conflict Over Sperm Transfer, Bert Foquet, Jack Thomas Mckermitt, John Hunt, Ben M. Sadd, Scott K. Sakaluk
Evolution Of Mate Guarding Intensity In Crickets As A Possible Adaptation To Sexual Conflict Over Sperm Transfer, Bert Foquet, Jack Thomas Mckermitt, John Hunt, Ben M. Sadd, Scott K. Sakaluk
Faculty Publications – Biological Sciences
Mate guarding is a common behavioral adaptation in males to ensure mating or to hinder current partners from remating with rival males. In the decorated cricket, Gryllodes sigillatus, males transfer a spermatophore to females at mating, comprising a sperm-containing ampulla enveloped in a large gelatinous mass, the spermatophylax, that serves as a nuptial food gift for the female. Males guard the female while she feeds on the nuptial gift and while sperm are evacuated from the ampulla into her reproductive tract. Mate guarding behavior functions to prevent competitors from mating with the female but may also represent a behavioral …
The Influence Of Historical Climate Cycles On The Diversification And Demography Of Species From The Neotropical Lizard Group Anolis Chrysolepis, Tony Gamble
Biological Sciences Faculty Research and Publications
Historical shifts in climate have significantly influenced the establishment of ecosystems and the evolution of species. Phylogeographical studies integrated with niche modelling can provide insights into divergence events and demography. This study explores the evolutionary history, demographic patterns, and spatiotemporal dynamics of seven South American lizard species of the Anolis chrysolepis species group, which has been proposed to be strongly impacted by Pleistocene climatic fluctuations under the Refugia Hypothesis. We utilized mitochondrial and nuclear DNA sequences to delineate lineages, estimate divergence times, and examine demographic dynamics. Ecological niche models were employed to assess historical range shifts and identify climatic stability …
House Flies (Musca Domestica) In Abu Dhabi Emirate: Assessing Deltamethrin Insecticide Resistance And Associated Microbial Communities, Mohamad Abdelrahim Hamdan
House Flies (Musca Domestica) In Abu Dhabi Emirate: Assessing Deltamethrin Insecticide Resistance And Associated Microbial Communities, Mohamad Abdelrahim Hamdan
Theses
This study investigates the common house fly (Musca domestica), a globally important insect that serves as both a decomposer and a mechanical vector for pathogens. The emergence of insecticide resistance, particularly knockdown resistance (kdr) mutations, has been reported in house fly populations, raising concerns for pest control. Additionally, house flies exhibit diverse bacterial communities, influencing pathogen transmission and environmental microbial dynamics. The primary objective of this study was to assess the prevalence of kdr mutations associated with insecticide resistance in house flies collected from the Abu Dhabi Emirate and to analyze their microbial composition using metagenomic approaches. House flies were …
Leveraging Arginine Catabolism To Treat Metabolic Complications, Yiming Zhang
Leveraging Arginine Catabolism To Treat Metabolic Complications, Yiming Zhang
Arts & Sciences Graduate Student Theses and Dissertations
Fasting and caloric restriction are effective to treat patients with pre-diabetes or metabolic dysfunction-associated steatotic liver disease (MASLD), previously known as non-alcoholic fatty liver disease (NAFLD), but intensive lifestyle changes are difficult for many to implement and sustain. Therefore, by identifying and studying fasting-mediated signals, we hope to elicit and convey the therapeutic effects of fasting against MASLD without actual physiological fasting. We discovered a key pathway in the liver through unbiased transcriptomic screening in fasted mice, a novel glucose fasting-activated effector: the amino acid hydrolase, arginase 2 (ARG2). Our previously published data demonstrates that forced hepatocyte-specific Arg2 overexpression is …
Variation In Thermal Tolerance Plasticity And The Costs Of Heat Exposure In The Estuarine Sea Hare, Phyllaplysia Taylori, Richelle L. Tanner, Rauri C. K. Bowie, Cynthia Y. Wang-Claypool, Jonathan H. Stillman
Variation In Thermal Tolerance Plasticity And The Costs Of Heat Exposure In The Estuarine Sea Hare, Phyllaplysia Taylori, Richelle L. Tanner, Rauri C. K. Bowie, Cynthia Y. Wang-Claypool, Jonathan H. Stillman
Biology, Chemistry, and Environmental Sciences Faculty Articles and Research
Climate change is increasing average temperatures and the frequency and intensity of thermal extremes in coastal marine environments. Organisms in coastal marine habitats are accustomed to environmental fluctuations and possess physiological plasticity that may be advantageous in response to increased occurrence of extremes. To examine whether such plasticity is locally adapted to environmental conditions, we investigated the relationship between genetic diversity and thermal tolerance plasticity in 11 populations of the direct-developing intertidal sea hare, Phyllaplysia taylori, on the western coast of the United States. Using whole-organism metrics of muscle function and metabolic rate and a ddRADseq genomic approach, we …
Survey Of Mosquito Larval Habitats At The Ksu Field Station, Rose Sofia, Eli Lovvorn, Aspen Hartman, Andrew Haddow
Survey Of Mosquito Larval Habitats At The Ksu Field Station, Rose Sofia, Eli Lovvorn, Aspen Hartman, Andrew Haddow
Symposium of Student Scholars
The greater Atlanta metropolitan area hosts numerous mosquito species that are nuisance biters and can transmit arthropod-borne diseases to humans. We surveyed the Kennesaw State University (KSU) Field Station – an incredibly biodiverse location – where student, staff, and faculty-led groups engage in outdoor research and teaching activities. The KSU Field Station located in Cobb County, GA is a heavily trafficked 25-acre property that may attract various mosquito species capable of transmitting pathogens to humans and animals alike. On August 27th, 2024, our team investigated the KSU Field Station to quantify and record potential water-holding containers that serve as mosquito …
Gubic: The Global Urban Biological Invasions Compendium For Plants, Daijiang Li, Luke J. Potgieter, Myla F. J. Aronson, Irena Axmanová, Benjamin Baiser, Marta Carboni, Laura Celesti-Grapow, Sonja Knapp, Ingolf Kühn, Ana Carolina Lacerda De Matos, Zdeňka Lososová, Flavia A. Montaño-Centellas, Petr Pyšek, David M. Richardson, Lauren B. Trotta, Rafael D. Zenni, Sarel S. Cilliers, Bruce D. Clarkson, Amy J. S. Davis, Rebecca W. Dolan, Marcin M. Dyderski, Franz Essl, Orou G. Gaoue, Joanne Gui, Charly Géron, Gustavo Heringer, Cang Hui, Anzar A. Khuroo, Stefan Klotz, Peter M. Kotanen, Holger Kreft, Frank A. Sorte, Jonas J. Lembrechts, Bernd Lenzner, Christopher A. Lepczyk, Scott Macivor, Cristina Martínez-Garza, Akira S. Mori, Charles Nilon, Jan Pergl, Stefan J. Siebert, Alyona S. Tretyakova, Toby P. N. Tsang, Kei Uchida, Mark Van Kleunen, Montserrat Vilà, Hua-Feng Wang, Patrick Weigelt, Peter Werner, Nicholas S. G. Williams, Marten Winter, Marc Cadotte
Gubic: The Global Urban Biological Invasions Compendium For Plants, Daijiang Li, Luke J. Potgieter, Myla F. J. Aronson, Irena Axmanová, Benjamin Baiser, Marta Carboni, Laura Celesti-Grapow, Sonja Knapp, Ingolf Kühn, Ana Carolina Lacerda De Matos, Zdeňka Lososová, Flavia A. Montaño-Centellas, Petr Pyšek, David M. Richardson, Lauren B. Trotta, Rafael D. Zenni, Sarel S. Cilliers, Bruce D. Clarkson, Amy J. S. Davis, Rebecca W. Dolan, Marcin M. Dyderski, Franz Essl, Orou G. Gaoue, Joanne Gui, Charly Géron, Gustavo Heringer, Cang Hui, Anzar A. Khuroo, Stefan Klotz, Peter M. Kotanen, Holger Kreft, Frank A. Sorte, Jonas J. Lembrechts, Bernd Lenzner, Christopher A. Lepczyk, Scott Macivor, Cristina Martínez-Garza, Akira S. Mori, Charles Nilon, Jan Pergl, Stefan J. Siebert, Alyona S. Tretyakova, Toby P. N. Tsang, Kei Uchida, Mark Van Kleunen, Montserrat Vilà, Hua-Feng Wang, Patrick Weigelt, Peter Werner, Nicholas S. G. Williams, Marten Winter, Marc Cadotte
Scholarship and Professional Work - LAS
Abstract Urban areas are foci for the introduction of non-native plant species, and they often act as launching sites for invasions into the wider environment. Although interest in biological invasions in urban areas is growing rapidly, and the extent and complexity of problems associated with invasions in these systems have increased, data on the composition and numbers of non-native plants in urbanized areas remain scattered and idiosyncratic. We assembled data from multiple sources to create the Global Urban Biological Invasions Compendium (GUBIC) for vascular plants representing 553 urban centres from 61 countries across every continent except Antarctica. The GUBIC repository …
The Therapeutic Potential Of Salvia Aegyptiaca Extracts In Ethanol-Induced Gastric Ulcer:Insights Into Macroscopic, Histopathological, And Biochemical Mechanisms, Walid Mamache, Smain Amira, Fatima Benchikh, Hassiba Benabdallah, Amor Bencheikh, Hind Amira, Roumaissa Ounis, Mohammed Abdallah Torki, Chahrazed Kaoudoune
The Therapeutic Potential Of Salvia Aegyptiaca Extracts In Ethanol-Induced Gastric Ulcer:Insights Into Macroscopic, Histopathological, And Biochemical Mechanisms, Walid Mamache, Smain Amira, Fatima Benchikh, Hassiba Benabdallah, Amor Bencheikh, Hind Amira, Roumaissa Ounis, Mohammed Abdallah Torki, Chahrazed Kaoudoune
Turkish Journal of Biology
Background/aim: This study explores the antiulcer activity of different doses of Salvia aegyptiaca (SAE) methanol (ME) and decoctedextracts (DE) on ethanol-induced gastric ulcers in rats.Materials and methods: Female Wistar rats weighing 180–200 g were divided into five groups: control, omeprazole (positive control),and extract-treated (100, 200, and 400 mg/kg). Ulcers were induced with absolute ethanol 30 min after treatment with the extracts.The experiment was followed by macroscopic and histopathological examination. In vitro tests were also conducted to assess lipidperoxidation, catalase activity, mucus content, glutathione, and protein levels.Results: The study found that 100% ethanol caused significant damage, including colour and mucus loss, …
Phytochemical Profile And Nematicidal Potential Of Essential Oil From Algerian Wildoriganum Vulgare Subsp. Glandulosum Defs., Amina Mezerket, Juan Emilio Palomares Rius, Souad Bouasla, Henia Saib
Phytochemical Profile And Nematicidal Potential Of Essential Oil From Algerian Wildoriganum Vulgare Subsp. Glandulosum Defs., Amina Mezerket, Juan Emilio Palomares Rius, Souad Bouasla, Henia Saib
Turkish Journal of Biology
Background/aim: The root gall nematode Meloidogyne incognita constitute the most damaging species that infects many crops inAlgeria. The intense use of harmful agricultural chemical products has incited research to develop alternative methods with natural andecological advantages like essential oils extracted from plants. The objective of this study was to evaluate the efficacy of Origanum vulgaresubsp. glandulosum Desf. (Lamiaceae) essential oil on the development of the root-knot nematode M. incognita in potted tomatoes.Materials and methods: In pot trials, we assess the activity of O. vulgare subsp. glandulosum essential oil at two concentrations of0.75 and 0.37 mg /L against M . incognita. …
Antidiabetic Potential Of Polysaccharides From Algerian Saharan Zygophyllum Geslini Instreptozotocin-Induced Diabetic Rats, Houria Medjdoub, Waffa Bouali, Arezki Azzi, Nacera Belkacem, Nabila Benariba, Nawel Meliani
Antidiabetic Potential Of Polysaccharides From Algerian Saharan Zygophyllum Geslini Instreptozotocin-Induced Diabetic Rats, Houria Medjdoub, Waffa Bouali, Arezki Azzi, Nacera Belkacem, Nabila Benariba, Nawel Meliani
Turkish Journal of Biology
Background/aim: Zygophyllum geslini, an endemic Algerian species, has numerous properties, especially as an antidiabeticdrug. In Algeria, this herb serves as condiment in Saharan dishes and as animal feed (Sheep, Goat and Camel). However, fewscientific studies have reported on the medicinal properties of this Saharan species. The aims of the present work were to study 1) thechemical aspects of polysaccharides extracted from this plant, 2) their inhibitory effect on pancreatic α-amylase in vitro, and 3) theirantihyperglycemic effect in streptozotocin-induced diabetic rats in vivo.Materials and methods: First, polysaccharides were extracted from Z. geslini aerial part (ZGAP) in hot water and precipitated withethanol …
Metal Complexes Of Sulfamethazine/Benzoin-Based Schiff Base Ligand: Synthesis,Characterization, Dft Calculations, And Antimicrobial Activities, Kerem Buran
Turkish Journal of Biology
Background/aim: The global rise in bacterial resistance poses a significant challenge, exacerbated by the overuse of antibacterial agents. Schiff base-metal complexes have gained attention for their potential antimicrobial properties, attributed to their unique three-dimensional structures and modes of action, such as cell wall inhibition and membrane disruption. The aim of this study was to synthesize and characterize a novel Schiff base (L) derived from sulfamethazine and benzoin, and to develop metal complexes of it with Cu2+, Co2+, Ni2+, and Cd2+. This research sought to evaluate the antibacterial and antifungal activities of the synthesized Schiff base and its metal complexes to …
Enhanced Formulation And Comprehensive Analysis Of Novel Natural Ointments Withgrape Seed And Pomegranate Peel Infused In Olive Oil, Mebarka Imane Benguechoua, Madjda Benguechoua, Khedidja Benarous, Alaeddine Kaouka, Mohamed Yousfi
Enhanced Formulation And Comprehensive Analysis Of Novel Natural Ointments Withgrape Seed And Pomegranate Peel Infused In Olive Oil, Mebarka Imane Benguechoua, Madjda Benguechoua, Khedidja Benarous, Alaeddine Kaouka, Mohamed Yousfi
Turkish Journal of Biology
Background/aim: The global shift toward sustainable and organic alternatives in cosmetics and personal care has created a demandfor innovative and environmentally conscious formulations. This study aimed to develop novel natural ointments using beeswax andgrape seed (GS) and pomegranate peel (PP) extracts infused in extra virgin olive oil (EVOO), and determine the physicochemicalcharacteristics, microbiological properties, and antioxidant activity as a way to valorize organic waste toward its application in thecosmetic industry. The research aimed to promote sustainability and effectiveness in the cosmetic industry.Materials and methods: Microbial analysis was performed on the oils and ointments, followed by the extraction of active compoundsusing …
Antilipase Activities Of Cultivated Peppermint And Rosemary Essential Oils:In Vitro And In Silico Studies, Khadidja Bengana, Talia Serseg, Khedidja Benarous, Ari̇f Mermer, Yakup Şi̇ri̇n, Alaeddine Kaouka
Antilipase Activities Of Cultivated Peppermint And Rosemary Essential Oils:In Vitro And In Silico Studies, Khadidja Bengana, Talia Serseg, Khedidja Benarous, Ari̇f Mermer, Yakup Şi̇ri̇n, Alaeddine Kaouka
Turkish Journal of Biology
Background/aim: The growing interest in essential oils clearly indicates the power of nature and aligns with our increasing need to findtherapeutic solutions in the natural world. This study aimed to investigate the inhibitory effects of the essential oils of Mentha × piperitaand Salvia rosmarinus, harvested from the Laghouat region of Algeria, against Candida rugosa lipase (CRL) and pancreatic lipasethrough both in vitro and in silico studies.Materials and methods: Essential oils were extracted via hydrodistillation and analyzed using gas chromatography–mass spectrometryand spectrophotometry. Their antilipase activities were assessed using an inhibition assay, and molecular docking was performed withAutoDock Vina to explore interactions …
Molecular Mechanisms Of Niemann-Pick Type C: Investigating Gene Expression, Lipid Metabolism, And Mitochondrial Dysfunction In Fibroblasts, Sarah Kim
Theses and Dissertations
Niemann-Pick Disease Type C (NPC) is a progressive lysosomal storage disorder characterized by the accumulation of lipids, particularly cholesterol, within cells, leading to severe neurological manifestations and developmental issues. This study employs RNA-seq to compare gene expression profiles between fibroblasts derived from a healthy individual and a patient with the NPC1 mutation. A total of 12,978 genes were analyzed, revealing 191 differentially expressed genes. Functional enrichment analysis disclosed significant associations with biological processes related to development, lipid metabolism, embryonic organ development, vascularization, and neuroinflammation. Additionally, the connection between mitochondrial function and lysosomal impairment was explored, revealing that NPC1 mutant fibroblasts …
Characterization Of 1,8-Cineole (Eucalyptol) From Myrtle And Its Potential Antibacterial And Antioxidant Activities*, Humera Khan
Characterization Of 1,8-Cineole (Eucalyptol) From Myrtle And Its Potential Antibacterial And Antioxidant Activities*, Humera Khan
Karbala International Journal of Modern Science
1,8-Cineole is a naturally occurring chemical molecule predominantly found in fragrant plants, particularly Myrtle. Its aroma is distinctive and has been the subject of numerous investigations due to its various biological actions. This study examines the characterization of 1,8-Cineole derived from Myrtle and investigates its antibacterial and antioxidant properties. This study seeks to compare 1,8-Cineole with antibiotics like Amoxicillin and Tetracycline, and moreover, to investigate its antioxidant capabilities against diverse bacterial strains (both Gram-positive and Gram-negative). 1,8-Cineole exhibits the most effective antibacterial properties, demonstrating an inhibition zone of 12.00 mm against Staphylococcus aureus and 10.00 mm against Pseudomonas aeruginosa. …
Life History, Reproductive, And Demographic Parameters For Bottlenose Dolphins (Tursiops Truncatus) In Sarasota Bay, Florida, Randall S. Wells, Aleta A. Hohn, Michael D. Scott, Jay C. Sweeney, Forrest I. Townsend, Jason B. Allen, Aaron A. Barleycorn, Katherine A. Mchugh, Kim Bassos-Hull, Gretchen N. Lovewell, Deborah A. Duffield, Cynthia R. Smith, A. Blair Irvine
Life History, Reproductive, And Demographic Parameters For Bottlenose Dolphins (Tursiops Truncatus) In Sarasota Bay, Florida, Randall S. Wells, Aleta A. Hohn, Michael D. Scott, Jay C. Sweeney, Forrest I. Townsend, Jason B. Allen, Aaron A. Barleycorn, Katherine A. Mchugh, Kim Bassos-Hull, Gretchen N. Lovewell, Deborah A. Duffield, Cynthia R. Smith, A. Blair Irvine
Biology Faculty Publications and Presentations
Studies of the resident community of bottlenose dolphins (Tursiops truncatus) of Sarasota Bay, Florida, have been conducted for more than 50 years. Detailed histories have been collected for resident individuals through integrated observations, systematic photographic identification surveys, tagging and tracking, catch-and-release health assessments, remote biopsy sampling, and stranding response. This has produced a unique dataset documenting life history milestones and vital rates of a small cetacean. Analyses of data from 482 resident Sarasota Bay dolphins have revealed estimated maximum life spans of 67 years for females and 52 years for males. For females, predicted age at sexual maturation …
A Mechanistic Exploration Of How Neighborhood Crime Exposure Relates To Neonatal Brain Function, Early Externalizing Behaviors, And Callous-Unemotional Traits, Rebecca Brady
Arts & Sciences Graduate Student Theses and Dissertations
Pregnancy through early childhood is a period of tremendous neural and behavioral development. Neuronal birth and migration occur prenatally and result in the formation of neonatal functional and structural networks. These early brain networks are a building block for postnatal development wherein infants rapidly learn a variety of new skills, including socioemotional skills such as emotion regulation and moral understanding. During the acquisition of these skills, even typically developing toddlers can act aggressively or impulsively; however, toddlers with high levels of externalizing behaviors are more likely to develop clinical externalizing disorders later in childhood and adolescence. As such, it is …
Additional Geographic Records Of Dekay’S Brownsnake (Storeria Dekayi) In Nebraska, Including A Late Seasonal Observation And Likely Range Expansion, Lauren Bahe, Dan D. Fogell, Keith Geluso
Additional Geographic Records Of Dekay’S Brownsnake (Storeria Dekayi) In Nebraska, Including A Late Seasonal Observation And Likely Range Expansion, Lauren Bahe, Dan D. Fogell, Keith Geluso
Transactions of the Nebraska Academy of Sciences and Affiliated Societies
Dekay’s Brownsnake (Storeria dekayi) occurs across much of eastern North America, inhabiting diverse environments such as marshes, woodlands, woodland edges, and urban areas. In Nebraska, recent studies documented its presence beyond the extreme southeastern region of the state, indicating a potential range expansion to the west and north. Our study continues to update its distribution with four additional county records. Two counties, Franklin and Harlan, represent the farthest west observations for Dekay’s Brownsnake in the state, further indicating a likely westward expansion. An observation from 6 December 2023 also represents the latest seasonal observation in the state. Despite …