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Articles 3961 - 3990 of 20626

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Biological Invasion Costs Reveal Insufficient Proactive Management Worldwide, Ross N. Cuthbert, Christophe Diagne, Emma J. Hudgins, Anna Turbelin, Danish A. Ahmed, Céline Albert, Thomas W. Bodey, Elizabeta Briski, Franz Essl, Phillip J. Haubrock, Rodolphe E. Gozlan, Natalia Kirichenko, Melina Kourantidou, Andrew M. Kramer, Franck Courchamp Jan 2022

Biological Invasion Costs Reveal Insufficient Proactive Management Worldwide, Ross N. Cuthbert, Christophe Diagne, Emma J. Hudgins, Anna Turbelin, Danish A. Ahmed, Céline Albert, Thomas W. Bodey, Elizabeta Briski, Franz Essl, Phillip J. Haubrock, Rodolphe E. Gozlan, Natalia Kirichenko, Melina Kourantidou, Andrew M. Kramer, Franck Courchamp

Integrative Biology Faculty and Staff Publications

The global increase in biological invasions is placing growing pressure on the management of ecological and economic systems. However, the effectiveness of current management expenditure is difficult to assess due to a lack of standardised measurement across spatial, taxonomic and temporal scales. Furthermore, there is no quantification of the spending difference between pre-invasion (e.g. prevention) and post-invasion (e.g. control) stages, although preventative measures are considered to be the most cost-effective. Here, we use a comprehensive database of invasive alien species economic costs (InvaCost) to synthesise and model the global management costs of biological invasions, in order to provide a better …

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Economic Costs Of Biological Invasions In The United States, Jean E. Fantle-Lepczyk, Phillip J. Haubrock, Andrew M. Kramer, Ross N. Cuthbert, Anna J. Turbelin, Robert Crystal-Ornelas, Christophe Diagne, Franck Courchamp Jan 2022

Economic Costs Of Biological Invasions In The United States, Jean E. Fantle-Lepczyk, Phillip J. Haubrock, Andrew M. Kramer, Ross N. Cuthbert, Anna J. Turbelin, Robert Crystal-Ornelas, Christophe Diagne, Franck Courchamp

Integrative Biology Faculty and Staff Publications

The United States has thousands of invasive species, representing a sizable, but unknown burden to the national economy. Given the potential economic repercussions of invasive species, quantifying these costs is of paramount importance both for national economies and invasion management. Here, we used a novel global database of invasion costs (InvaCost) to quantify the overall costs of invasive species in the United States across spatiotemporal, taxonomic, and socioeconomic scales. From 1960 to 2020, reported invasion costs totaled $4.52 trillion (USD 2017). Considering only observed, highly reliable costs, this total cost reached $1.22 trillion with an average annual cost of …

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Knowledge Gaps In Economic Costs Of Invasive Alien Fish Worldwide, Phillip J. Haubrock, Camille Bernery, Ross N. Cuthbert, Chunlong Liu, Melina Kourantidou, Boris Leroy, Anna J. Turbelin, Andrew M. Kramer, Laura N.H. Verbrugge, Christophe Diagne, Franck Courchamp, Rodolphe E. Gozlan Jan 2022

Knowledge Gaps In Economic Costs Of Invasive Alien Fish Worldwide, Phillip J. Haubrock, Camille Bernery, Ross N. Cuthbert, Chunlong Liu, Melina Kourantidou, Boris Leroy, Anna J. Turbelin, Andrew M. Kramer, Laura N.H. Verbrugge, Christophe Diagne, Franck Courchamp, Rodolphe E. Gozlan

Integrative Biology Faculty and Staff Publications

Invasive alien fishes have had pernicious ecological and economic impacts on both aquatic ecosystems and human societies. However, a comprehensive and collective assessment of their monetary costs is still lacking. In this study, we collected and reviewed reported data on the economic impacts of invasive alien fishes using InvaCost, the most comprehensive global database of invasion costs. We analysed how total (i.e. both observed and potential/predicted) and observed (i.e. empirically incurred only) costs of fish invasions are distributed geographically and temporally and assessed which socioeconomic sectors are most affected. Fish invasions have potentially caused the economic loss of at least …

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Blue Mussel Hybrid Complex Shifts In The Gulf Of Maine Towards A Dominance Of Mytilus Edulis, Daniel Woods Jan 2022

Blue Mussel Hybrid Complex Shifts In The Gulf Of Maine Towards A Dominance Of Mytilus Edulis, Daniel Woods

Honors Program Theses

The Gulf of Maine (GOM) in the United States is the fastest warming body of water in the world. Due to a complex history of glaciation, the GOM has restricted circulation that causes it to function more akin to an enclosed sea. As climate change has disrupted the stable flow of the Gulf Stream, more warm-water currents are entering the GOM at higher frequency. This warming has had a profound impact on the distribution of the blue mussel, Mytilus spp., which inhabits the rocky intertidal habitat within the GOM as the main prey species to a keystone predator. Two sister …

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Analysis Of Hematocrit Levels In Walleye Sander Vitreus From Similar Waterbodies, Alyssa Hauser Jan 2022

Analysis Of Hematocrit Levels In Walleye Sander Vitreus From Similar Waterbodies, Alyssa Hauser

Journal of Earth and Life Science

Walleye Sander vitreus are a popular fish among anglers and hold a prominent place in Minnesotan’s identity as their state fish. Because of this, multiple management practices are used to ensure the continued health of their populations within Minnesota waters. In this study, the process of analyzing hematocrit levels was used to determine if the analysis of hematological parameters could be a useful tool in detecting differences in population health. To evaluate this, blood samples were acquired from age-0 and age-1 fish from two similar lakes and run through a hematocrit centrifuge to separate platelets from plasma to read the …

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The Effects Of Diet On Yellow Perch Morphology Throughout Lake Bemidji, Quiana L. Radaich Jan 2022

The Effects Of Diet On Yellow Perch Morphology Throughout Lake Bemidji, Quiana L. Radaich

Journal of Earth and Life Science

Morphology is very important as it looks at the arrangement of an organism’s parts to determine their functionality, development, and how they could have changed through evolution. It is also important for the identification of species as it can show how closely species are related. This study examines if the morphology of yellow perch changes throughout Lake Bemidji. Along with examining a subset of five stomachs for each group (A-F) of yellow perch collected to determine if diet was a driving force behind morphological changes. The data collected in this study suggested that morphology does change throughout Lake Bemidji and …

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Multiomic Hypotheses Underlying Behavioral Manipulation Of Camponotus Floridanus Ants By Ophiocordyceps Camponoti-Floridani Fungi, Ian Will Jan 2022

Multiomic Hypotheses Underlying Behavioral Manipulation Of Camponotus Floridanus Ants By Ophiocordyceps Camponoti-Floridani Fungi, Ian Will

Electronic Theses and Dissertations, 2020-2023

Parasitic manipulation of host behavior lies at the intersection of disease, animal behavior, and coevolutionary processes. In many of these interactions, the underpinning biology is brought into sharp focus as they are obligate relationships, under strong selection to bring about specific changes in host behavior that determine if the parasite will transmit or die. However, experimental and molecular techniques to understand these interactions are still developing and identification of the mechanisms of manipulation is a primary goal in the field. As such, we investigated host-parasite interactions between Camponotus floridanus (Florida carpenter ant) and Ophiocordyceps camponoti-floridani (Florida zombie ant fungus) from …

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An Expert-Curated Global Database Of Online Newspaper Articles On Spiders And Spider Bites, Stefano Mammola, Laura Segura-Hernández, Et Al. Jan 2022

An Expert-Curated Global Database Of Online Newspaper Articles On Spiders And Spider Bites, Stefano Mammola, Laura Segura-Hernández, Et Al.

School of Biological Sciences: Faculty Publications

Mass media plays an important role in the construction and circulation of risk perception associated with animals. Widely feared groups such as spiders frequently end up in the spotlight of traditional and social media. We compiled an expert-curated global database on the online newspaper coverage of human-spider encounters over the past ten years (2010– 2020). This database includes information about the location of each human-spider encounter reported in the news article and a quantitative characterisation of the content—location, presence of photographs of spiders and bites, number and type of errors, consultation of experts, and a subjective assessment of sensationalism. In …

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Elucidation Of Novel And Established Campylobacter Species With Clinical And Agricultural Significance Through Phenotypic, Genotypic, And Taxonomic Investigation, Caoimhe Lynch Jan 2022

Elucidation Of Novel And Established Campylobacter Species With Clinical And Agricultural Significance Through Phenotypic, Genotypic, And Taxonomic Investigation, Caoimhe Lynch

Theses

Campylobacter spp. are well-established human, veterinary and economic pathogens, with a broad host range spanning from terrestrial and marine mammalian, avian and reptilian hosts. The scope of the study includes novel and notorious species within the genus, with reference to zoonotic agents Campylobacter jejuni and Campylobacter coli - the leading cause of human bacterial gastroenteritis in the EU and Ireland, Campylobacter fetus that represents the most common campylobacter causing bacteraemia and two novel species isolated from pigs not described in the literature previously. C. jejuni and C. coli isolates (n = 350) recovered from broiler caecal and neck skin samples, …

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Optimising The Carcass Merit Of Irish Beef Cattle Using Genetic And Non-Genetic Information At The Animal And Herd Level, David Kenny Jan 2022

Optimising The Carcass Merit Of Irish Beef Cattle Using Genetic And Non-Genetic Information At The Animal And Herd Level, David Kenny

Theses

Failure of beef carcasses to achieve desirable carcass specifications represent inefficiencies within the supply chain, namely greater carcass processing costs and the inability of the resulting primal cuts to conform to high-value market specifications. Analysis of a representative sample of prime Irish beef cattle conducted in this thesis determined that 59% of cattle fail to achieve the desired carcass specifications of the supply chain at slaughter. The objective of this thesis was to use readily available information to define strategies that could help to reduce this statistic. Firstly, the likelihood of Irish beef carcasses achieving the desired carcass specifications was …

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Bottom-Up Effects Of Degradation Outweighs Stabilizing Potential Of Omnivores, Hannah Marie Moore Jan 2022

Bottom-Up Effects Of Degradation Outweighs Stabilizing Potential Of Omnivores, Hannah Marie Moore

Murray State Theses and Dissertations

Anthropogenic activities have led to degradation in streams throughout much of Western North America. In particular, cattle grazing has led to a loss of riparian vegetation resulting in higher water temperatures and an increase in nutrient runoff. The effects of degradation on food quality and quantity for aquatic consumers could have large implications for stream communities. Since omnivores feed at multiple trophic levels, they may be resilient to altered food webs, which may allow them to stabilize communities in degraded environments where resources have been reduced. To test the hypothesis that omnivores positively impact community stability in degraded conditions, I …

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Development Of Hemic Neoplasia In The Soft-Shell Clam (Mya Arenaria) Along The East Coast Of The United States, Nicole B. Seitz Jan 2022

Development Of Hemic Neoplasia In The Soft-Shell Clam (Mya Arenaria) Along The East Coast Of The United States, Nicole B. Seitz

West Chester University Master’s Theses

Hemic neoplasia (HN) is a bivalve disease characterized by uncontrolled proliferation of abnormal hemocytes that invade solid tissue, similar to vertebrate leukemia, ultimately leading to death. High disease prevalence has been reported in many bivalve populations, yet disease etiology and development remain minimally understood. In this study, nine East Coast populations of soft-shell clams (Mya arenaria) were evaluated between 2011-2012 to identify environmental and health factors associated with HN. PCA analysis and statistical testing were used to compare data at and between each population based on HN status. The percentage of organisms with terminal stage 4 HN (76-100% …

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Effect Of Metal-Containing Nanoparticles On Bacterial Biofilms And On The Microbiome Of Girardia Tigrina, Azar Saikali Jan 2022

Effect Of Metal-Containing Nanoparticles On Bacterial Biofilms And On The Microbiome Of Girardia Tigrina, Azar Saikali

West Chester University Master’s Theses

Anthropogenically-produced nanoparticles are a form of nanotechnology being used in industries including food and textiles. Humans and livestock are frequently exposed to metal-containing nanoparticles (MCNPs), that have been washed into streams and rivers, have been deliberately used in food packaging as antimicrobials, preservatives or for supplementation. The animal microbiome, which consists of a diverse community of microorganisms, provides a number of benefits to the host in terms of nutrition availability, immune support, and can influence behavior. Biofilms of diverse microbes may cause detrimental effects, for instance by causing dental diseases in humans. However, the scientific community has not reached consensus …

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Fibropapillomatosis And Chelonid Herpesvirus 5 Dynamics In Juvenile Green Turtles Of The Indian River Lagoon, Florida, Usa, Jake Kelley Jan 2022

Fibropapillomatosis And Chelonid Herpesvirus 5 Dynamics In Juvenile Green Turtles Of The Indian River Lagoon, Florida, Usa, Jake Kelley

Electronic Theses and Dissertations, 2020-2023

Fibropapillomatosis (FP) is a tumor-forming sea turtle disease that mainly affects juvenile green turtles (Chelonia mydas) in coastal foraging sites. The cause of FP is unclear, but likely involves the putative pathogen chelonid herpesvirus 5 (ChHV5). The overall dynamics of this disease are poorly understood, in part due to the difficulty of inferring disease and infection statuses of turtles without evidence of FP. In this study, I investigated the FP disease system in juvenile green turtles of the Indian River Lagoon (IRL), Florida, USA, to better understand disease and pathogen dynamics. First, I developed a hierarchical model for predicting FP …

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Factors Related To Species Richness, Endemism, And Conservation Status Of The Herpetofauna (Amphibia And Reptilia) Of Mexican States, Geoffrey R. Smith, Julio A. Lemos-Espinal Jan 2022

Factors Related To Species Richness, Endemism, And Conservation Status Of The Herpetofauna (Amphibia And Reptilia) Of Mexican States, Geoffrey R. Smith, Julio A. Lemos-Espinal

Faculty Publications

No abstract provided.

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Final Report Floating Upwelling System Harvest Road Oceans, Robert Michael, Scott Bennett Jan 2022

Final Report Floating Upwelling System Harvest Road Oceans, Robert Michael, Scott Bennett

Fisheries Occasional Publications

A Floating Upwelling System or FLUPSY is a mechanical system for the culture of seed stock during the nursery stage of commercial bivalve production.

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Characterizing Cellular Stress, Hippocampal Function, And Behavior In A Novel Rat Model Of Alzheimer's Disease, Anne A. Schulman Jan 2022

Characterizing Cellular Stress, Hippocampal Function, And Behavior In A Novel Rat Model Of Alzheimer's Disease, Anne A. Schulman

Honors Theses

Alzheimer’s Disease (AD) is a progressive neurodegenerative disorder that affects over 5 million individuals in the United States alone. While AD is primarily thought of as a disease that destroys neural networks required for memory recall and formation, AD also cause impairment in emotional regulation, cognitive flexibility, and executive function pathways. The cause of AD is unknown; however, the allele ApoE4 has been identified as a risk factor for the onset of AD. ApoE4 provides a valuable opportunity to study AD through animal models. This thesis utilized a human ApoE4 transgenic rat model (hApoE4) to investigate the biological and behavioral …

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Avian Eggshell Coloration Predicts Shell-Matrix Protoporphyrin Content, Charles F. Thompson, Kara E. Hodges, Nathan T. Mortimer, Alysia D. Vrailas-Mortimer, Scott K. Sakaluk, Mark E. Hauber Jan 2022

Avian Eggshell Coloration Predicts Shell-Matrix Protoporphyrin Content, Charles F. Thompson, Kara E. Hodges, Nathan T. Mortimer, Alysia D. Vrailas-Mortimer, Scott K. Sakaluk, Mark E. Hauber

Faculty Publications – Biological Sciences

Avian eggshell pigmentation may provide information about a female’s physiological condition, in particular her state of oxidative balance. Previously we found that female House Wrens (Troglodytes aedon Vieillot, 1809) with lighter, less-maculated, and redder ground-colored shells were older and produced heavier offspring than females laying more-maculated and browner eggs. The strong pro-oxidant protoporphyrin is responsible for this species’ eggshell pigmentation, so differences in pigmentary coloration may be related to eggshell protoporphyrin content and reflect female oxidative balance and condition during egg formation. Therefore, we tested the assumption that egg-surface coloration is related to the amount of protoporphyrin in the …

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New Baraminological Methods Confirm Monobaraminic Status Of The Horses (Perissodactyla: Equidae) And Preliminary Analyses Of New Datasets Suggest The Possibility Of Discontinuity Between Horses And Various Outgroup Taxa, Timothy R. Brophy, Jack Gregory, Mary-Elizabeth Tallman, Kara Ray Jan 2022

New Baraminological Methods Confirm Monobaraminic Status Of The Horses (Perissodactyla: Equidae) And Preliminary Analyses Of New Datasets Suggest The Possibility Of Discontinuity Between Horses And Various Outgroup Taxa, Timothy R. Brophy, Jack Gregory, Mary-Elizabeth Tallman, Kara Ray

Faculty Publications and Presentations

No abstract provided.

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Modeling The Flow And Creep Compliance Properties Of Ice-Cream Mixes, Hiran Ranaweera Jan 2022

Modeling The Flow And Creep Compliance Properties Of Ice-Cream Mixes, Hiran Ranaweera

Electronic Theses and Dissertations

This work documented the influence of the protein source (MPC80 and WPC80), protein content (4-12%), and temperature (5-35ºC) on the rheological behavior (flow curve, frequency sweep, and creep-recovery) of ice-cream mixes (ICM). For each protein source, the viscosity of the ICM was satisfactorily modeled (𝑅2>0.98, 𝑅2 𝑎𝑑𝑗>0.98, and E0.99), while the recovery phase was represented by an empirical model. The percentage of recovery (%R) of the ICM significantly decreased with the protein content.

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Spatio-Temporal Movement Patterns Of Sub-Adult Adfluvial Bull Trout, Aimee Taylor Jan 2022

Spatio-Temporal Movement Patterns Of Sub-Adult Adfluvial Bull Trout, Aimee Taylor

All Master's Theses

Bull Trout in the Yakima River basin of Washington are primarily adfluvial, often using managed lakes as habitat. Kachess Lake, composed of Big and Little Kachess Lakes, is managed by the Bureau of Reclamation (BOR) for water storage. BOR plans to build a structure that can withdraw an additional 200,000 acre-feet of water in drought years, which would disconnect the two basins for multiple years. This study examined the spatio-temporal movement of sub-adult Bull Trout in Kachess Lake to understand distribution patterns and the effects of environmental variables. We sought to answer 1) does time (week of the year), diel …

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Standardized Neon Organismal Data For Biodiversity Research, Daijiang Li, Sydne Record, Eric R. Sokol, Matthew E. Bitters, Melissa Y. Chen, Y. Anny Chung, Matthew R. Helmus, Ruvi Jaimes, Lara Jansen, Marta A. Jarzyna, Michael G. Just, Jalene M. Lamontagne, Brett A. Melbourne, Wynne Moss, Kari E. A. Norman, Stephanie M. Parker, Natalie Robinson, Bijan Seyednasrollah, Colin Smith, Sarah Spaulding, Thilina D. Surasinghe, Sarah K. Thomsen, Phoebe L. Zarnetske Jan 2022

Standardized Neon Organismal Data For Biodiversity Research, Daijiang Li, Sydne Record, Eric R. Sokol, Matthew E. Bitters, Melissa Y. Chen, Y. Anny Chung, Matthew R. Helmus, Ruvi Jaimes, Lara Jansen, Marta A. Jarzyna, Michael G. Just, Jalene M. Lamontagne, Brett A. Melbourne, Wynne Moss, Kari E. A. Norman, Stephanie M. Parker, Natalie Robinson, Bijan Seyednasrollah, Colin Smith, Sarah Spaulding, Thilina D. Surasinghe, Sarah K. Thomsen, Phoebe L. Zarnetske

Biology Faculty Research and Scholarship

Understanding patterns and drivers of species distribution and abundance, and thus biodiversity, is a core goal of ecology. Despite advances in recent decades, research into these patterns and processes is currently limited by a lack of standardized, high-quality, empirical data that span large spatial scales and long time periods. The NEON fills this gap by providing freely available observational data that are generated during robust and consistent organismal sampling of several sentinel taxonomic groups within 81 sites distributed across the United States and will be collected for at least 30 years. The breadth and scope of these data provide a …

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Comparing Physiological Responses To Hot And Cold Stress In A Cnidarian–Algal Holobiont, Exaiptasia Diaphana, Nicole Capozzi, Eyananda Ahmed, Ezra Curtis, Olivia Grandbois, Dominique Kelly, Kadin Kristjansson, Natalie Morgan, Louis Schlecker, Rachel M. Wright Jan 2022

Comparing Physiological Responses To Hot And Cold Stress In A Cnidarian–Algal Holobiont, Exaiptasia Diaphana, Nicole Capozzi, Eyananda Ahmed, Ezra Curtis, Olivia Grandbois, Dominique Kelly, Kadin Kristjansson, Natalie Morgan, Louis Schlecker, Rachel M. Wright

Other Student Projects

Coral bleaching—the breakdown of the cnidarian–algal symbiosis—is a major cause of reef decline. The sea anemone Exaiptasia diaphana, commonly known as Aiptasia, is used as a model to study cnidarian-algal symbiosis in laboratory settings. Aiptasia can live with or without symbionts, which allows scientists to study the host combined and separate from the influence of the symbionts. Scientists are able to trigger the breakdown of the symbiosis using heat or cold stress. Cold stress is more commonly used to render aposymbiotic Aiptasia because it seems to be less harmful to the host than bleaching under heat stress. Is cold …

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Assessment Of Digital Imaging Flow Cytometry In Its Application Of Harmful Algal Blooms Monitoring, Melissa Mazzaro Jan 2022

Assessment Of Digital Imaging Flow Cytometry In Its Application Of Harmful Algal Blooms Monitoring, Melissa Mazzaro

Theses, Dissertations and Culminating Projects

As harmful algal blooms (HABs) are becoming an increasing global threat to the health of people, animals, and aquatic ecosystems, finding ways to efficiently detect and manage blooms is critical. Traditional methods of identifying and enumerating phytoplankton cells involve light microscopy; however, this is a time-consuming and labor-intensive process. Meanwhile, digital imaging flow cytometry is a relatively novel and rapid method of enumerating and identifying particles within phytoplankton samples. Previous studies have documented comparable digital flow cytometry results to microscopy results; however, there are concerns relating to the underestimation of cells and misidentification of particles with their automated classification systems. …

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Evaluation Of Aquatic Plant Survey Methods For Efficacy In Invasive Species Detection, Izaac Cooper Jan 2022

Evaluation Of Aquatic Plant Survey Methods For Efficacy In Invasive Species Detection, Izaac Cooper

Legacy Theses & Dissertations (2009 - 2024)

Aquatic invasive plants can often be ecologically devastating to ecosystems where they are introduced. This devastation has been widely apparent in the United States, including many locations in New York State over many decades, following anthropogenic transport of species from their native ranges. Due to the difficulty involved in eradicating these plants once they have become fully established, there is keen interest in strategies for early detection to assist with prevention and monitoring to mitigate future management costs. Invasive species detection research aims to find methods for detecting new invaders more effectively. I evaluated three detection methods for their effectiveness …

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Mechanisms Underlying Pre- And Postnatal Development Of The Mouse Vomeronasal Organ, Raghu Ram Katreddi Jan 2022

Mechanisms Underlying Pre- And Postnatal Development Of The Mouse Vomeronasal Organ, Raghu Ram Katreddi

Legacy Theses & Dissertations (2009 - 2024)

The Vomeronasal organ (VNO) is a specialized olfactory sensory organ located in the ventral region of the nasal cavity in rodents. The vomeronasal epithelium (VNE) of rodents is composed of 2 major types of vomeronasal sensory neurons (VSNs): 1) VSNs distributed in the apical VNE regions that express vomeronasal type-1 receptors (V1Rs) and the G protein subunit Gi2, and 2) VSNs in the basal territories of the VNE that express vomeronasal type-2 receptors (V2Rs) and the G subunit Go. Besides these two neuronal types, VNE also accommodate a third non-neuronal cell type called Sustentacular cells that lie anatomically above apical …

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Rna-Seq Data Analysis Of A Human Lung Carcinoma Cell Line (A549) And Investigating The Role Of Nf-Kappa B As An Effector Of Atf3 During Zika Virus Infection, Theodora Pearl De-Veer Jan 2022

Rna-Seq Data Analysis Of A Human Lung Carcinoma Cell Line (A549) And Investigating The Role Of Nf-Kappa B As An Effector Of Atf3 During Zika Virus Infection, Theodora Pearl De-Veer

Legacy Theses & Dissertations (2009 - 2024)

The 2015 Zika virus (ZIKV) outbreak amassed international concern due to its association with the high incidence of devastating neurological conditions- microcephaly and Guillain-Barré Syndrome. Reportedly affecting over 5,000 fetal newborns, imaging studies have unveiled the pernicious effects of ZIKV infection on the fetal brain, which include cortical malformations, micrencephaly, hydrocephalus, and focal inflammation.

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Fluorescent Biosensors : Engineering And Applications, Monica Rodriguez Jan 2022

Fluorescent Biosensors : Engineering And Applications, Monica Rodriguez

Legacy Theses & Dissertations (2009 - 2024)

Neurons in the brain communicate via electrical and chemical synapses, whereneurotransmitters are released. Traditional methods to detect synaptic transmission rely on single-cell patch-clamp recordings from target neurons, but these can only provide an indirect readout of the lifetime of neurotransmitters in the extracellular space. More recently, this task has been aided by developing fluorescent biosensors with high sensitivity and large dynamic ranges. Fluorescent biosensors are typically composed of a neurotransmitter binding protein tagged with fluorescent reporter molecules. Fluorescence biosensors come in different forms, including FRET-based biosensors. These can be built using different intracellular signaling molecules and neurotransmitter binding domains. Here, …

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Length–Weight Relation For Seven Neotropical Freshwater Fish Species (Actinopterygii) Endemic To Central America, Justin C. Bagley, Maria Florencia Breitman, Jerald B. Johnson Jan 2022

Length–Weight Relation For Seven Neotropical Freshwater Fish Species (Actinopterygii) Endemic To Central America, Justin C. Bagley, Maria Florencia Breitman, Jerald B. Johnson

Research, Publications & Creative Work

In the presently reported study, we estimated length–weight relation (LWRs) for seven species of freshwater fishes from Central America. Samples were collected using seines from 60 sites across Nicaragua, Costa Rica, and Panama during field expeditions conducted between 1997 and 2012. The fishes were preserved and transported to the lab, where their total weight (W) was measured (to nearest 0.0001 g) and standard lengths were taken (to nearest 0.01 mm). Data were collected from four livebearers (Poeciliidae), Alfaro cultratus (Regan, 1908), Phallichthys amates (Miller, 1907), Poecilia gillii (Kner, 1863), and Priapichthys annectens (Regan, 1907); the cichlids (Cichlidae), Parachromis dovii (Günther, …

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Gemcitabine In Combination With Epibrassinolide Enhanced The Apoptotic Response In An Er Stress-Dependent Manner And Reduced The Epithelial-Mesenchymal Transition In Pancreatic Cancer Cells, Pinar Obakan Yerli̇kaya, Leila Mehdizadehtapeh, Özge Rencüzoğullari, Fadina Kuryayeva, Sena Sedef Çevi̇kli̇, Şevval Özağar, Si̇bel Pinar Odabaş, Sude Tunçkol, Hakan Yeti̇m, Ajda Çoker Gürkan, Eli̇f Damla Arisan Jan 2022

Gemcitabine In Combination With Epibrassinolide Enhanced The Apoptotic Response In An Er Stress-Dependent Manner And Reduced The Epithelial-Mesenchymal Transition In Pancreatic Cancer Cells, Pinar Obakan Yerli̇kaya, Leila Mehdizadehtapeh, Özge Rencüzoğullari, Fadina Kuryayeva, Sena Sedef Çevi̇kli̇, Şevval Özağar, Si̇bel Pinar Odabaş, Sude Tunçkol, Hakan Yeti̇m, Ajda Çoker Gürkan, Eli̇f Damla Arisan

Turkish Journal of Biology

Gemcitabine is a broad-spectrum antimetabolite and a deoxycytidine analog recognized as a standard therapy alone or in combination with other antineoplastic agents in the therapy of pancreas cancer. Drug resistance following gemcitabine treatment is a common phenomenon; therefore, combinational therapy models are usually preferred. Pancreatic ductal adenocarcinoma, or pancreas cancer, is the fourth leading cause of cancer-related deaths worldwide. With the increasing incidence of pancreatic cancer every year, the mortality rate is also rising significantly because of late diagnosis, and limited chemotherapy options. Adjuvant chemotherapy after surgical resection is the typical option for the treatment of early pancreatic cancer. Mostly, …

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