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Evolution Of Complex Sperm Morphology, Dawn M. Higginson Jan 2011

Evolution Of Complex Sperm Morphology, Dawn M. Higginson

Biology - Dissertations

Sperm form evolves rapidly and dramatically, particularly in taxa with internal fertilization. Post-copulatory sexual selection at the level of individual sperm has been suggested to explain the evolution of two enigmatic sperm phenotypes: sperm heteromorphism, where more than one type of sperm is produced by a male, and sperm conjugation, where multiple sperm join together for motility and transport through the female reproductive tract before dissociation prior to fertilization. I explore the taxonomic distribution of sperm heteromorphism and conjugation, speculate on the potential developmental origins and discuss functional hypotheses for evolutionary maintenance of these remarkable traits. I subsequently focus on …


Summer 2011, Nova Southeastern University Jan 2011

Summer 2011, Nova Southeastern University

Currents

No abstract provided.


Economics, Behavioral Biology, And Law, Jeffrey E. Stake, Owen D. Jones, Erin O'Hara O'Connor Jan 2011

Economics, Behavioral Biology, And Law, Jeffrey E. Stake, Owen D. Jones, Erin O'Hara O'Connor

Articles by Maurer Faculty

This article compares the relevance to law of two unexpectedly similar fields: economics and behavioral biology. It first examines the assumptions, core concepts, methodological tenets, and emphases of the two fields. It then compares the interdisciplinary fields of law and economics, on one hand, with law and behavioral biology, on the other-highlighting not only important similarities but also important differences. The article subsequently explores ways that biological perspectives on human behavior may, among other things, improve economic models and the behavioral insights they generate. The article concludes that although there are important differences between the two fields, the overlaps between …


Positive Selection Shaped The Convergent Evolution Of Independently Expanded Kallikrein Subfamilies Expressed In Mouse And Rat Saliva Proteomes, Robert C. Karn, Christina M. Laukaitis Jan 2011

Positive Selection Shaped The Convergent Evolution Of Independently Expanded Kallikrein Subfamilies Expressed In Mouse And Rat Saliva Proteomes, Robert C. Karn, Christina M. Laukaitis

Scholarship and Professional Work - LAS

We performed proteomics studies of salivas from the genome mouse (C57BL/6 strain) and the genome rat (BN/SsNHsd/Mcwi strain). Our goal was to identify salivary proteins with one or more of three characteristics that may indicate that they have been involved in adaptation: 1) rapid expansion of their gene families; 2) footprints of positive selection; and/or 3) sex-limited expression. The results of our proteomics studies allow direct comparison of the proteins expressed and their levels between the sexes of the two rodent species. Twelve members of the Mus musculus species-specific kallikrein subfamily Klk1b showed sex-limited expression in the mouse saliva proteomes. …


Angler Survey Of The Connecticut River, Justin P. Davis Jan 2011

Angler Survey Of The Connecticut River, Justin P. Davis

EEB Articles

The Connecticut River is the largest and most diverse inland fishery resource in the State of Connecticut. Significant improvements in water quality over the past 30 years have led to progressive increases in recreational use, presumably increasing fishing pressure on some species and possibly decreasing overall fishing quality. To address this concern, the Inland Fisheries Division (IFD) of the Connecticut Department of Energy and Environmental Protection (CT DEEP) conducted an angler survey on the entire portion of the Connecticut River within the state during March-October of 2008-09. The survey used a similar design as a smaller-scale survey of the river’s …


Mojave Applied Ecology Notes Winter 2011, Scott R. Abella, Alice C. Newton, Kenneth Chittick, Pam Sinanian Jan 2011

Mojave Applied Ecology Notes Winter 2011, Scott R. Abella, Alice C. Newton, Kenneth Chittick, Pam Sinanian

Mojave Applied Ecology Notes

Lake Mead’s collaborative applied science research program; “annoying the elephant” - ruminations on active management by Alice Newton, Lake Mead NRA vegetation manager; 2012 NWRA Lake Mead symposium sneak peak; assessing forest change using dendrochronology in the Spring Mountains.


"A Revision Of The Freshwater Crabs Of Lake Kivu, East Africa." , Neil Cumberlidge, Kirstin S. Meyer Jan 2011

"A Revision Of The Freshwater Crabs Of Lake Kivu, East Africa." , Neil Cumberlidge, Kirstin S. Meyer

Journal Articles

No abstract provided.


Analyses Of Fruit Flies That Do Not Express Selenoproteins Or Express The Mouse Selenoprotein, Methionine Sulfoxide Reductase B1, Reveal A Role Of Selenoproteins In Stress Resistance, Valentina A. Shchedrina, Hadise Kabil, Gerd Vorbruggen, Byung Cheon Lee, Anton A. Turanov, Mitsuko Hirosawa- Takamori, Hwa- Young Kim, Lawrence G. Harshman, Dolph L. Hatfield, Vadim N. Gladyshev Jan 2011

Analyses Of Fruit Flies That Do Not Express Selenoproteins Or Express The Mouse Selenoprotein, Methionine Sulfoxide Reductase B1, Reveal A Role Of Selenoproteins In Stress Resistance, Valentina A. Shchedrina, Hadise Kabil, Gerd Vorbruggen, Byung Cheon Lee, Anton A. Turanov, Mitsuko Hirosawa- Takamori, Hwa- Young Kim, Lawrence G. Harshman, Dolph L. Hatfield, Vadim N. Gladyshev

School of Biological Sciences: Faculty Publications

Selenoproteins are essential in vertebrates because of their crucial role in cellular redox homeostasis, but some invertebrates that lack selenoproteins have recently been identified. Genetic disruption of selenoprotein biosynthesis had no effect on lifespan and oxidative stress resistance of Drosophila melanogaster. In the current study, fruit flies with knock-out of the selenocysteine-specific elongation factor were metabolically labeled with 75Se; they did not incorporate selenium into proteins and had the same lifespan on a chemically defined diet with or without selenium supplementation. These flies were, however, more susceptible to starvation than controls, and this effect could be ascribed to the …


The Arabidopsis Trithorax-Like Factor Atx1 Functions In Dehydration Stress Responses Via Aba-Dependent And Aba-Independent Pathways, Yong Ding, Zoya Avramova, Michael Fromm Jan 2011

The Arabidopsis Trithorax-Like Factor Atx1 Functions In Dehydration Stress Responses Via Aba-Dependent And Aba-Independent Pathways, Yong Ding, Zoya Avramova, Michael Fromm

School of Biological Sciences: Faculty Publications

Emerging evidence suggests that the molecular mechanisms driving the responses of plants to environmental stresses are associated with specific chromatin modifications. Here, we demonstrate that the Arabidopsis trithorax-like factor ATX1, which trimethylates histone H3 at lysine 4 (H3K4me3), is involved in dehydration stress signaling in both abscisic acid (ABA)-dependent and ABA-independent pathways. The loss of function of ATX1 results in decreased germination rates, larger stomatal apertures, more rapid transpiration and decreased tolerance to dehydration stress in atx1 plants. This deficiency is caused in part by reduced ABA biosynthesis in atx1 plants resulting from decreased transcript levels from NCED3, which …


Aphids: A Model For Polyphenism And Epigenetics, Dayalan G. Srinivasan, Jennifer A. Brisson Jan 2011

Aphids: A Model For Polyphenism And Epigenetics, Dayalan G. Srinivasan, Jennifer A. Brisson

School of Biological Sciences: Faculty Publications

Environmental conditions can alter the form, function, and behavior of organisms over short and long timescales, and even over generations. Aphid females respond to specific environmental cues by transmitting signals that have the effect of altering the development of their offspring. These epigenetic phenomena have positioned aphids as a model for the study of phenotypic plasticity. The molecular basis for this epigenetic inheritance in aphids and how this type of inheritance system could have evolved are still unanswered questions. With the availability of the pea aphid genome sequence, new genomics technologies, and ongoing genomics projects in aphids, these questions can …


Maize Cellulosic Biofuels: Soil Carbon Loss Can Be A Hidden Cost Of Residue Removal, Amy Kochsiek, Johannes Knops Jan 2011

Maize Cellulosic Biofuels: Soil Carbon Loss Can Be A Hidden Cost Of Residue Removal, Amy Kochsiek, Johannes Knops

School of Biological Sciences: Faculty Publications

Second generation biofuels, like cellulosic ethanol, have potential as important energy sources that can lower fossil fuel carbon emissions without affecting global food commodity prices. Agricultural crop residues, especially maize, have been proposed for use as biofuel, but the net greenhouse warming effect of the gained fossil fuel carbon offset needs to account for any ecosystem carbon losses caused by the large-scale maize residue removal. Using differential 13C isotopic ratios between residue and soil in an incubation experiment, we found that removal of residue increased soil organic matter decomposition by an average of 16%, or 540–800 kg carbon ha -1. …


Survival Rates Of Planidial Larvae Of The Parasitoid Fly Ormia Ochracea (Diptera: Tachinidae), Oliver M. Beckers, Cassandra M. Martin, William E. Wagner Jr. Jan 2011

Survival Rates Of Planidial Larvae Of The Parasitoid Fly Ormia Ochracea (Diptera: Tachinidae), Oliver M. Beckers, Cassandra M. Martin, William E. Wagner Jr.

School of Biological Sciences: Faculty Publications

The tachinid fly, Ormia ochracea Bigot 1889, is a major parasitoid of field crickets in North America. The fly ranges from Florida to California, and it has also been introduced to Hawaii. Across this range, O. ochracea uses at least 6 different Gryllus species as hosts for its larvae (Cade, 1975; Walker, 1986; Walker and Wineriter, 1991; Zuk et al., 1993; Wagner, 1996; Hedrick and Kortet, 2006). O. ochracea finds it hosts by eavesdropping on male mating songs (Cade, 1975). The fly deposits up to 3 planidial larvae (Adamo et al., 1995a) directly on the male and these …


Dtorsin, The Drosophila Ortholog Of The Early-Onset Dystonia Tor1a (Dyt1), Plays A Novel Role In Dopamine Metabolism, Noriko Wakabayashi-Ito, Olugbenga M. Doherty, Hideaki Moriyama, Xandra O. Breakefield, James F. Gusella, Janis M. O’Donnell, Naoto Ito Jan 2011

Dtorsin, The Drosophila Ortholog Of The Early-Onset Dystonia Tor1a (Dyt1), Plays A Novel Role In Dopamine Metabolism, Noriko Wakabayashi-Ito, Olugbenga M. Doherty, Hideaki Moriyama, Xandra O. Breakefield, James F. Gusella, Janis M. O’Donnell, Naoto Ito

School of Biological Sciences: Faculty Publications

Dystonia represents the third most common movement disorder in humans. At least 15 genetic loci (DYT1-15) have been identified and some of these genes have been cloned. TOR1A (formally DYT1), the gene responsible for the most common primary hereditary dystonia, encodes torsinA, an AAA ATPase family protein. However, the function of torsinA has yet to be fully understood. Here, we have generated and characterized a complete loss-of-function mutant for dtorsin, the only Drosophila ortholog of TOR1A. Null mutation of the X-linked dtorsin was semi-lethal with most male flies dying by the prepupal stage and the few surviving …


Identification Of Fabrics Likely To Collect And Disperse Fel D 1, Mary Janice Jones Jan 2011

Identification Of Fabrics Likely To Collect And Disperse Fel D 1, Mary Janice Jones

Electronic Theses and Dissertations

Individuals sensitive to domestic cat allergen Fel d 1 experience a variety of symptoms including eye irritation, respiratory irritation, asthma, and severe respiratory distress. Fel d 1 is a protein produced in the saliva and on the skin of domestic cats. Previous studies have demonstrated that Fel d 1 adheres to clothing, upholstery, and human hair and has been found in non-cat environments in levels high enough to cause allergic reactions in sensitive individuals. In a general sense, two very different approaches have been adopted to study Fel d 1. One area of the literature focuses on the molecular biology …


Investigating The Role Of Calcineurin In Axon Growth And Development Of Retinal Neurons, Jesus Iniguez Jan 2011

Investigating The Role Of Calcineurin In Axon Growth And Development Of Retinal Neurons, Jesus Iniguez

Undergraduate Honors Theses

This research project entails the characterization of Calcineurin (CaN) in neuron development. CaN is an intracellular protein that has been implicated in different systems as a mediator between cells and their surroundings to promote normal, healthy function (Lee & Park; 2006). Receptors on the surface of cells are known to stimulate intracellular changes, CaN is thought to mediate some of these changes, including during neurodevelopment. As a neuron develops, it extends a process (axon) in search of a specific target with which to form a synapse. Initial embryonic axon growth is directly related to axon growth and regeneration in adults. …


The Mayfly Newsletter, Peter M. Grant Jan 2011

The Mayfly Newsletter, Peter M. Grant

The Mayfly Newsletter

The Mayfly Newsletter is the official newsletter of the Permanent Committee of the International Conferences on Ephemeroptera.


Intra-Specific Variation Across A Small Temperature Difference In The Spider Rabidosa Rabida (Araneae: Lycosidae) From The Mountains In Arkansas, Ryan Joseph Stork Jan 2011

Intra-Specific Variation Across A Small Temperature Difference In The Spider Rabidosa Rabida (Araneae: Lycosidae) From The Mountains In Arkansas, Ryan Joseph Stork

Biology Dissertations - Archive

Temperature affects all levels of biological organization and ultimately affects multiple aspects of ecological performance and fitness. Generalist arthropod predators are ectothermic and are strongly affected by temperature in ways that are not fully understood. Descriptions of thermal ecology of important generalist arthropod predators are, therefore, essential pieces of information for studying ecology in changing thermal environments. Rabidosa rabida is a wolf spider that inhabits much of the eastern United States and plays an important role as a generalist predator of large herbivorous arthropods. This study makes the first description of the thermal ecology of R. rabida. A description of …


The Decline Of Soft Inheritance, Scott F. Gilbert Jan 2011

The Decline Of Soft Inheritance, Scott F. Gilbert

Biology Faculty Works

No abstract provided.


Evolution Of The Actin Gene Family In Testate Lobose Amoebae (Arcellinida) Is Characterized By Two Distinct Clades Of Paralogs And Recent Independent Expansions, Daniel J.G. Lahr, Truc B. Nguyen, Erika Barbero, Laura A. Katz Jan 2011

Evolution Of The Actin Gene Family In Testate Lobose Amoebae (Arcellinida) Is Characterized By Two Distinct Clades Of Paralogs And Recent Independent Expansions, Daniel J.G. Lahr, Truc B. Nguyen, Erika Barbero, Laura A. Katz

Biological Sciences: Faculty Publications

The evolution of actin gene families is characterized by independent expansions and contractions across the eukaryotic tree of life. Here, we assess diversity of actin gene sequences within three lineages of the genus Arcella, a free-living testate (shelled) amoeba in the Arcellinida. We established four clonal lines of two morphospecies, Arcella hemisphaerica and A. vulgaris, and assessed their phylogenetic relationship within the "Amoebozoa" using small subunit ribosomal DNA (SSU-rDNA) genealogy. We determined that the two lines of A. hemisphaerica are identical in SSU-rDNA, while the two A. vulgaris are independent genetic lineages. Furthermore, we characterized multiple actin gene copies from …


Ontogenetic Changes In The Bell Morphology And Kinematics And Swimming Behavior Of Rowing Medusae: The Special Case Of The Limnomedusa Liriope Tetraphylla, Tasia Blough, Sean Colin, John H. Costello, Antonio C. Marques Jan 2011

Ontogenetic Changes In The Bell Morphology And Kinematics And Swimming Behavior Of Rowing Medusae: The Special Case Of The Limnomedusa Liriope Tetraphylla, Tasia Blough, Sean Colin, John H. Costello, Antonio C. Marques

Arts & Sciences Faculty Publications

Swimming animals may experience significant changes in the Reynolds number (Re) of their surrounding fluid flows throughout ontogeny. Many medusae experience Re environments with significant viscous forces as small juveniles but inertially dominated Re environments as adults. These different environments may affect their propulsive strategies. In particular, rowing, a propulsive strategy with ecological advantages for large adults, may be constrained by viscosity for small juvenile medusae. We examined changes in the bell morphology and swimming kinematics of the limnomedusa Liriope tetraphylla at different stages of development. L. tetraphylla maintained an oblate bell (fineness ratio _ 0.5–0.6), large velar …


Ecogeographical Distribution Of The Herpetofauna Of Indio Mountains Research Station, Hudspeth County, Texas, Ross Owen Couvillon Jan 2011

Ecogeographical Distribution Of The Herpetofauna Of Indio Mountains Research Station, Hudspeth County, Texas, Ross Owen Couvillon

Open Access Theses & Dissertations

Indio Mountain Research Station (IMRS) in Trans-Pecos, Texas is dominated by Chihuahuan Desert scrub vegetation, but a complexity of plant communities exist relating to elevation, slope, and geologic formations. Surrounding the Indio Mountains are desert grasslands with various desert scrub associations. This mosaic of habitats forms a unique assemblage of amphibians and reptiles. The goal of this study was to determine if the current number of amphibians, turtles, lizards, and snakes (43 species) of IMRS was accurate and identify which biotic and abiotic factors define the distribution of these species. Records from the last approximately 25 years were used to …


Diet, Growth And Bioenergetics Of Northern Pike (Esox Lucius Linnaeus, 1758) In Box Canyon Reservoir, Pend Oreille River, Washington, Shane Joseph Harvey Jan 2011

Diet, Growth And Bioenergetics Of Northern Pike (Esox Lucius Linnaeus, 1758) In Box Canyon Reservoir, Pend Oreille River, Washington, Shane Joseph Harvey

EWU Masters Thesis Collection

"The objectives of this study were to describe the growth of northern pike, describe the food habits of northern pike and using bioenergetics modeling assess the mass and total numbers of each species of forage fish the northern pike population consumed in Box Canyon Reservoir,Pend Orielle River, Washington. Northern pike (n=328) were collected by boat electrofishing, fyke netting, angling and gillnetting in 2009 and 2010. All northern pike were sacrificed to obtain stomach contents. Stomach contents were examined in the laboratory and identified to the appropriate level; amphibians and mammals to species, insect prey (aquatic/terrestrial) to family and prey fish …


Ecology Of The Rock Rattlesnake, Crotalus Lepidus, In The Northern Chihuahuan Desert, Vicente Mata Silva Jan 2011

Ecology Of The Rock Rattlesnake, Crotalus Lepidus, In The Northern Chihuahuan Desert, Vicente Mata Silva

Open Access Theses & Dissertations

The Rock Rattlesnake, Crotalus lepidus is a small species that is found from southern Arizona, southern New Mexico, and southern Texas, in the U.S., into northern Mexico. To date, little is known about the ecology of this species. Ecological information is becoming desperately needed for supporting the conservation and protection of species living in fragile environments such as the Chihuahuan Desert amid current local and global threats (e.g., habitat destruction and modification, urban development, and climate change). Although rattlesnakes spend a significant amount of time underground while overwintering, little is known about the physiology and behavior of these organisms during …


Variation, Systematics, And Relationships Of The Leptodactylus BolivianusComplex (Amphibia: Anura: Leptodactylidae), W. R. Heyer, Rafael O. De Sá Jan 2011

Variation, Systematics, And Relationships Of The Leptodactylus BolivianusComplex (Amphibia: Anura: Leptodactylidae), W. R. Heyer, Rafael O. De Sá

Biology Faculty Publications

A cluster of morphologically similar frogs of the genus Leptodactylus having a pair of distinct dorsolateral folds on the dorsum and well-developed lateral fringes on the toes has never been systematically evaluated by examining materials from throughout its geographic range. The species involved are herein referred to as members of the Leptodactylus bolivianus complex. There have been three names proposed for members of this complex: Leptodactylus bolivianus Boulenger, 1898; Leptodactylus insularum Barbour, 1906; and Leptodactylus romani Melin, 1941. The collective range for the L. bolivianus complex is from Costa Rica southward through Panama, extending across northern South America (east of …


Altitudinal Variation Of Freeze Tolerance In The Pacific Chorus Frog, Pseudacris Regilla, Sara Healas Jan 2011

Altitudinal Variation Of Freeze Tolerance In The Pacific Chorus Frog, Pseudacris Regilla, Sara Healas

Undergraduate Honors Theses

This study compares the physiological responses to freezing of Pacific Chorus frogs (Pseudacris regilla) from low-elevation and high-elevation sites. During the winter months, Pacific Chorus frogs have the ability to freeze solid and revive upon thawing. They survive freezing because they store massive amounts of glycogen that they convert into glucose once freezing starts. Glucose is use (1) to protect the cells during freezing and (2) to support general metabolism through the entire winter. The hypothesis is that the frogs collected at the high-elevation site will have more glucose stored as glycogen because these frogs have to survive …


Investigating The Effects Of The Plasticizers Bisphenol A And Di (2-Ethylhexyl) Phthalate On Dopaminergic Neurons In A C. Elegans Parkinson's Disease, Amanda Valera Jan 2011

Investigating The Effects Of The Plasticizers Bisphenol A And Di (2-Ethylhexyl) Phthalate On Dopaminergic Neurons In A C. Elegans Parkinson's Disease, Amanda Valera

Undergraduate Honors Theses

Parkinson's disease (PD) is a neurodegenerative disorder characterized by loss of dopamine (DA) containing neurons in the substantia nigra of the brain. Though the cellular pathways that lead to PD are varied and not well understood, elevated levels of reactive oxygen species (ROS) and inhibition of the mitochondrial electron transport chain enzyme complex I have been associated with PD pathogenesis. Environmental factors such as the plasticizers bisphenol A (BPA) and di(2-ethylhexyl) phthalate (DEHP) may also be involved in PD pathogenesis. In this research, three strains of the nematode Caenorhabditis elegans (C. elegans), a wild-type N2 strain, a ROS-sensitive nnt …


The Impact Of Tricaine Methanesulfonate, 2-Phenoxyethanol, And Carvone-Methyl Salicylate On The Innate Immune Response Of Zebrafish (Danio Rerio), Charles R. Wulff Jan 2011

The Impact Of Tricaine Methanesulfonate, 2-Phenoxyethanol, And Carvone-Methyl Salicylate On The Innate Immune Response Of Zebrafish (Danio Rerio), Charles R. Wulff

Honors Theses

Anesthesia plays a vital role in the maintenance of aquaculture species, where it is used to minimize stress during complex handling tasks such as transport, assessment, and harvesting. However, anesthetics have been shown to suppress the innate immune response, which could impact immunity and increase risk of infection. Tricaine methanesulfonate (MS-222) and 2-Phenoxyethanol (2-PE) represent two of the most commonly used anesthetics in aquaculture, with R-(+)-carvone, in the form of carvone-methyl salicylate (CMS) has recently been proposed as an alternative anesthetic for food fish. These three anesthetics were used to assess the influence of anesthetics on the immune system of …


Social Dimensions Of Lake Ecology: Stakeholder Perception Surveys Used To Design Effective Lake Management Plans, Laurie Nannini Jan 2011

Social Dimensions Of Lake Ecology: Stakeholder Perception Surveys Used To Design Effective Lake Management Plans, Laurie Nannini

Masters Theses

Lake conservation management plans have exhibited varying levels of success through out Illinois. Recent research, in eutrophic lakes shows that pollution at any level stabilizes when stakeholder cooperation is enhanced by high conformist tendency and social concern. Involving stakeholders in preliminary stages of lake management plans creates more legitimacy and connectedness with the local government as well as stakeholder involvement with management plans. Public opinion data also allows policy makers to sustainably involve stakeholders in management plans. Members of the Illinois Lake Management Association were surveyed on their perceived threats to lakes, preferences on lake facilities and activities. Responses were …


Is Anthropogenic Habitat Change The Driving Force Of Rapid Evolution Of Southeastern U.S. Coastal Deer Populations?, Nicole L. Storm Jan 2011

Is Anthropogenic Habitat Change The Driving Force Of Rapid Evolution Of Southeastern U.S. Coastal Deer Populations?, Nicole L. Storm

Masters Theses

Many factors, such as genetics, food availability and the exact food species, can affect the growth rate and asymptotic size of animals. Since the I 960's, the coastal areas and islands in Georgia, North Carolina, and South Carolina have become vacation destinations with large and lavish resort communities built to accommodate the large number of visitors to areas that were once called home by just a small number of residents. These developments brought with them non-native plants and improved soil quality for both native and non-native plants. During this same time period, the whitetailed deer ( Odocoileus virginianus) native to …


Skeletal Muscle Gender Dimorphism From Proteomics, Kalina Dimova, Lauren Ann Metskas, Mohini Kulp, Stylianos P. Scordilis Jan 2011

Skeletal Muscle Gender Dimorphism From Proteomics, Kalina Dimova, Lauren Ann Metskas, Mohini Kulp, Stylianos P. Scordilis

Biological Sciences: Faculty Publications

Gross contraction in skeletal muscle is primarily determined by a relatively small number of contractile proteins, however this tissue is also remarkably adaptable to environmental factors such as hypertrophy by resistance exercise and atrophy by disuse. It thereby exhibits remodeling and adaptations to stressors (heat, ischemia, heavy metals, etc.). Damage can occur to muscle by a muscle exerting force while lengthening, the so-called eccentric contraction. The contractile proteins can be damaged in such exertions and need to be repaired, degraded and/or resynthesized; these functions are not part of the contractile proteins, but of other much less abundant proteins in the …