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The Role Of Enampt-Mediated Systemic Nad+ Biosynthesis In Aging And Lifespan, Mitsukuni Yoshida May 2021

The Role Of Enampt-Mediated Systemic Nad+ Biosynthesis In Aging And Lifespan, Mitsukuni Yoshida

Arts & Sciences Electronic Theses and Dissertations

Aging is a systemic decline in tissue functions that occurs during the course of our life leading to the development of age-associated health deteriorations and ultimately to the expiration of life. Over the past few decades, population aging has become increasingly evident in many parts of the world, leading to increased prevalence of age-related disabilities and diseases. Because age is a major risk factor for many chronic diseases, extensive research effort has been spent to identify common age-associated molecular changes contributing to the pathogenesis and progression of these health issues. One such molecule identified to play a central role in …


Testing The Common-Mechanisms Theory Of False Hearing And False Memory: The Roles Of Executive Functioning And Inhibitory Control, Eric Failes Jan 2021

Testing The Common-Mechanisms Theory Of False Hearing And False Memory: The Roles Of Executive Functioning And Inhibitory Control, Eric Failes

Arts & Sciences Electronic Theses and Dissertations

Recent studies have shown that older adults are more susceptible to context-based misperceptions in hearing than are younger adults, a phenomenon that has been referred to as false hearing (Rogers et al., 2012; Sommers et al., 2015). The authors of these studies have noted similarities between false hearing and false memories (Jacoby et al., 2005), suggesting that the two phenomena may arise from similar cognitive mechanisms. The present dissertation project investigated similarities between false hearing and false memories. In Experiment 1, I directly compared susceptibility to false hearing and false memories in younger and older adults. I then investigated two …