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- Brachytherapy (4)
- Medical Applications of Synchrotron Radiation (4)
- Synchrotron (4)
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- Dose (2)
- Energy (2)
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- Eye (2)
- Ophthalmic (2)
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- Planning (2)
- Plaque (2)
- Radiation (2)
- Ropes (2)
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- 125 (1)
- 3d (1)
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- Assurance (1)
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- Characterisation (1)
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Articles 1 - 8 of 8
Full-Text Articles in Science and Technology Studies
The Evaluation Of A 2d Diode Array In "Magic Phantom" For Use In High Dose Rate Brachytherapy Pretreatment Quality Assurance, Anthony A. Espinoza, Marco Petasecca, Iolanda Fuduli, Andrew Howie, Joseph A. Bucci, Stephanie Corde, Michael Jackson, Michael L. F Lerch, Anatoly B. Rosenfeld
The Evaluation Of A 2d Diode Array In "Magic Phantom" For Use In High Dose Rate Brachytherapy Pretreatment Quality Assurance, Anthony A. Espinoza, Marco Petasecca, Iolanda Fuduli, Andrew Howie, Joseph A. Bucci, Stephanie Corde, Michael Jackson, Michael L. F Lerch, Anatoly B. Rosenfeld
Stéphanie Corde
Purpose: High dose rate (HDR) brachytherapy is a treatment method that is used increasingly worldwide. The development of a sound quality assurance program for the verification of treatment deliveries can be challenging due to the high source activity utilized and the need for precise measurements of dwell positions and times. This paper describes the application of a novel phantom, based on a 2D 11 x 11 diode array detection system, named "magic phantom" (MPh), to accurately measure plan dwell positions and times, compare them directly to the treatment plan, determine errors in treatment delivery, and calculate absorbed dose. Methods: The …
Optimal Energy For Cell Radiosensitivity Enhancement By Gold Nanoparticles Using Synchrotron-Based Monoenergetic Photon Beams, Wan Nordiana Rahman, Stephanie Corde, Naoto Yagi, Siti Aishah Abdul Aziz, Nathan Annabell, Moshi Geso
Optimal Energy For Cell Radiosensitivity Enhancement By Gold Nanoparticles Using Synchrotron-Based Monoenergetic Photon Beams, Wan Nordiana Rahman, Stephanie Corde, Naoto Yagi, Siti Aishah Abdul Aziz, Nathan Annabell, Moshi Geso
Stéphanie Corde
Gold nanoparticles have been shown to enhance radiation doses delivered to biological targets due to the high absorption coefficient of gold atoms, stemming from their high atomic number (Z) and physical density. These properties significantly increase the likelihood of photoelectric effects and Compton scattering interactions. Gold nanoparticles are a novel radiosensitizing agent that can potentially be used to increase the effectiveness of current radiation therapy techniques and improve the diagnosis and treatment of cancer. However, the optimum radiosensitization effect of gold nanoparticles is strongly dependent on photon energy, which theoretically is predicted to occur in the kilovoltage range of energy. …
I-125 Ropes Eye Plaque Dosimetry: Validation Of A Commercial 3d Ophthalmic Brachytherapy Treatment Planning System And Independent Dose Calculation Software With Gafchromic Ebt3 Films, Joel Poder, Stephanie Corde
I-125 Ropes Eye Plaque Dosimetry: Validation Of A Commercial 3d Ophthalmic Brachytherapy Treatment Planning System And Independent Dose Calculation Software With Gafchromic Ebt3 Films, Joel Poder, Stephanie Corde
Stéphanie Corde
Purpose: The purpose of this study was to measure the dose distributions for different Radiation Oncology Physics and Engineering Services, Australia (ROPES) type eye plaques loaded with I-125 (model 6711) seeds using GafChromic R EBT3 films, in order to verify the dose distributions in the Plaque SimulatorTM (PS) ophthalmic 3D treatment planning system. The brachytherapy module of RADCALC R was used to independently check the dose distributions calculated by PS. Correction factors were derived from the measured data to be used in PS to account for the effect of the stainless steel ROPES plaque backing on the 3D dose distribution. …
The Feasibility Study And Characterziation Of A Two-Dimensional Diode Array In “Magic Phantom” For High Dose Rate Brachytherapy Quality Assurance, A Espinoza, B Beeksma, M Petasecca, I Fuduli, C Porumb, D L. Cutajar, S Corde, M A. Jackson, M Lf Lerch, Anatoly B. Rosenfeld
The Feasibility Study And Characterziation Of A Two-Dimensional Diode Array In “Magic Phantom” For High Dose Rate Brachytherapy Quality Assurance, A Espinoza, B Beeksma, M Petasecca, I Fuduli, C Porumb, D L. Cutajar, S Corde, M A. Jackson, M Lf Lerch, Anatoly B. Rosenfeld
Stéphanie Corde
High dose rate (HDR) brachytherapy is a radiation treatment technique capable of delivering large dose rates to the tumor. Radiation is delivered using remote afterloaders to drive highly active sources (commonly 192Ir with an air KERMA strength range between 20 000 and 40 000 U, where 1 U = 1 uGy m2/h in air) through applicators directly into the patient's prescribed region of treatment. Due to the obvious ramifications of incorrect treatment while using such an active source, it is essential that there are methods for quality assurance (QA) that can directly and accurately verify the treatment plan and the …
Synchrotron Radiation Computed Tomography Station At The Esrf Biomedical Beamline, C Nemoz, S Bayat, G Berruyer, T Brochard, P Coan, G Le Duc, J Keyrilainen, S Monfraix, M Renier, H Requardt, A Bravin, P Tafforeau, J F. Adam, M C. Biston, C Boudou, A M. Charvet, S Corde, H Elleaume, F Esteve, A Joubert, J Rousseau, I Tropres, M Fernandez, L Porra, P Suortti, S Fiedler, W Thomlinson
Synchrotron Radiation Computed Tomography Station At The Esrf Biomedical Beamline, C Nemoz, S Bayat, G Berruyer, T Brochard, P Coan, G Le Duc, J Keyrilainen, S Monfraix, M Renier, H Requardt, A Bravin, P Tafforeau, J F. Adam, M C. Biston, C Boudou, A M. Charvet, S Corde, H Elleaume, F Esteve, A Joubert, J Rousseau, I Tropres, M Fernandez, L Porra, P Suortti, S Fiedler, W Thomlinson
Stéphanie Corde
The different tomography imaging modalities of the ESRF Medical Beamline are described and research applications are presented
Synchrotron Radiation Based Experimental Determination Of The Optimal Energy For Cell Radiotoxicity Enhancement Following Photoelectric Effect On Stable Iodinated Compounds, S Corde, A Joubert, J F. Adam, A M. Charvet, J F. Le Bas, F Esteve, H Elleaume, J Balosso
Synchrotron Radiation Based Experimental Determination Of The Optimal Energy For Cell Radiotoxicity Enhancement Following Photoelectric Effect On Stable Iodinated Compounds, S Corde, A Joubert, J F. Adam, A M. Charvet, J F. Le Bas, F Esteve, H Elleaume, J Balosso
Stéphanie Corde
This study was designed to experimentally evaluate the optimal X-ray energy for increasing the radiation energy absorbed in tumours loaded with iodinated compounds, using the photoelectric effect. SQ20B human cells were irradiated with synchrotron monochromatic beam tuned at 32.8, 33.5, 50 and 70 keV. Two cell treatments were compared to the control: cells suspended in 10 mg ml1 of iodine radiological contrast agent or cells pre-exposed with 10 mM of iodo-desoxyuridine (IUdR) for 48 h. Our radiobiological end point was clonogenic cell survival. Cells irradiated with both iodine compounds exhibited a radiation sensitisation enhancement. Moreover, it was energy dependent, with …
Ropes Eye Plaque Dosimetry: Commissioning And Verification Of An Ophthalmic Brachytherapy Treatment Planning System, J Poder, N Annabell, M Geso, M Alqathami, S Corde
Ropes Eye Plaque Dosimetry: Commissioning And Verification Of An Ophthalmic Brachytherapy Treatment Planning System, J Poder, N Annabell, M Geso, M Alqathami, S Corde
Stéphanie Corde
In this study, the Plaque SimulatorTM eye plaque brachytherapy planning system was commissioned for ROPES eye plaques and Amersham Health model 6711 Iodine 125 seeds, using TG43-UI data. The brachytherapy module of the RADCALC® independent checking program was configured to allow verification of the accuracy of the dose calculated by Plaque SimulatorTM. Central axis depth dose distributions were compared and observed to agree to within 2% for all ROPES plaque models and depths of interest. Experimental measurements were performed with a customized PRESAGEm 3-D type dosimeter to validate the calculated depth dose distributions. Preliminary results have shown the effect of …
Fricke Dosimetry For Synchrotron Stereotactic Radiotherapy, C Boudou, M C Biston, J F Adam, A Joubert, S Corde, A M Charvet, F Esteve, H Elleaume
Fricke Dosimetry For Synchrotron Stereotactic Radiotherapy, C Boudou, M C Biston, J F Adam, A Joubert, S Corde, A M Charvet, F Esteve, H Elleaume
Stéphanie Corde
In synchrotron stereotactic radiotherapy (SSR) the tumor is loaded with a high Z element, and exposed to monochromatic x-rays from a synchrotron source, in stereotactic conditions. The SSR treatment efficiency is related to the heavy element concentration achievable in the tumor, to the radiation energy, and the irradiation geometry [1,2]. The experimental dose verification of SSR in three dimensions with a good spatial resolution is highly desirable for radiotherapy [3]. In this study, Fricke dosimeter and Monte Carlo calculations were employed for assessing 2D dose distribution.