Science and Technology Studies Commons^™

First In Vitro Evidence Of Modulated Electro-Hyperthermia Treatment Performance In Combination With Megavoltage Radiation By Clonogenic Assay, Marjorie Mcdonald, Stephanie Corde, Michael L. F Lerch, Anatoly B. Rosenfeld, Michael A. Jackson, Moeava Tehei

Faculty of Engineering and Information Sciences - Papers: Part B

Modulated electro-hyperthermia (mEHT) is a form of hyperthermia used in the treatment of cancer. It is a variation that relies on a particular form of enhanced selectivity to enable more effective cancerous cell death yet maintaining the integrity of healthy non-cancerous cells. It is yet to successfully make the major step into the wider medical community despite several encouraging trials. In this study, we investigate mEHT from an in vitro perspective. We demonstrate a supra-additive effect on 9 L gliosarcoma cells when exposed to mEHT in combination with MV X-ray radiation. The supra-additive effect is hypothesized to be induced by …