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Full-Text Articles in Other Psychology

Long-Term Effects Of Adolescent Fluoxetine Exposure On Hippocampal Gene Expression In Male C57bl/6 Mice, Anapaula Themann Dec 2021

Long-Term Effects Of Adolescent Fluoxetine Exposure On Hippocampal Gene Expression In Male C57bl/6 Mice, Anapaula Themann

Open Access Theses & Dissertations

Mood-related disorders, including depression and anxiety, are prevalent among children and adolescents. This poses a public health challenge, given their adverse impact on these young populations. Treatment with the selective serotonin reuptake inhibitor fluoxetine (FLX) is the first line of pharmacological intervention in pediatric patients suffering from affect-related illnesses. Although the use of this antidepressant has been deemed efficacious in the juvenile population, the enduring neurobiological consequences of adolescent FLX exposure are not well understood. For this reason, we explored for persistent molecular adaptations, in the adult hippocampus, as a function of adolescent FLX pretreatment. To do this, we administered …


Here Today, Gone Tomorrow: Impacts Of Friendship Stability And Homophily On Justice-Involved Juveniles' Offending And Substance Use, Anna Dmitriyevna Drozdova Jun 2021

Here Today, Gone Tomorrow: Impacts Of Friendship Stability And Homophily On Justice-Involved Juveniles' Offending And Substance Use, Anna Dmitriyevna Drozdova

Open Access Theses & Dissertations

Stable friendships in adolescence are associated with a variety of benefits such as strengthened social skills (Newcomb & Bagwell, 1995) and positive social adjustment (Hartup & Stevens, 1997), while unstable friendships are associated with a variety of problem behaviors such as delinquency and substance use (Miller, 2002). Further, greater friendship stability is associated with greater friendship homophily (i.e., similarity among friends; Carrington, 2015), and stable and homophilous friendships of delinquent adolescents may have deleterious consequences due to modeled and reinforced problem behaviors. However, few studies have explored how friendship stability and homophily operate specifically among justice-involved youths. Using data collected …