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A Psychometric Evaluation Of The Treatment Self-Regulation Questionnaire (Tsrq) For Assessing Motivations For Responsible Drinking, Dylan Keith Richards
A Psychometric Evaluation Of The Treatment Self-Regulation Questionnaire (Tsrq) For Assessing Motivations For Responsible Drinking, Dylan Keith Richards
Open Access Theses & Dissertations
Self-determination theory (SDT) may be useful for understanding alcohol use and alcohol-related consequences among college students. A version of the Treatment Self-Regulation Questionnaire (TSRQ; Ryan & Connell, 1989) exists for assessing motivations proposed by SDT for responsible drinking, but no study has evaluated its psychometric properties. Thus, the purpose of the present studies was to provide a psychometric evaluation of this version of the TSRQ. In Study 1, among a convenience sample of college student drinkers (n = 308), a four-factor structure of the TSRQ that is theoretically consistent with SDT was supported; however, the amotivation subscale demonstrated unacceptable internal …
Fluoxetine Exposure Results In Decreased Sensitivity To Cocaine And Sucrose Later In Life: A Study In Female C57bl/6 Mice, Francisco Javier Flores Ramirez
Fluoxetine Exposure Results In Decreased Sensitivity To Cocaine And Sucrose Later In Life: A Study In Female C57bl/6 Mice, Francisco Javier Flores Ramirez
Open Access Theses & Dissertations
Preclinical evidence indicates that exposure to psychotropic medications, during early development, results in long-lasting altered responses to stress- and reward-related stimuli. However, these animal studies have been conducted, primarily, using male subjects. This is surprising, given that clinical data suggests that females have a higher likelihood, than their male counterparts, to be diagnosed with mood-related illnesses, and thus, be prescribed with psychotropic medications, mostly antidepressants. Therefore, to examine whether enduring reward-related alterations are exhibited as a result of antidepressant exposure, in female subjects specifically, we exposed C57BL/6 female mice to fluoxetine (FLX; 250 mg/l in their drinking water). Specifically, separate …
Insulin Modulates The Strong Reinforcing Effects Of Nicotine And Changes In Insulin Biomarkers In A Rodent Model Of Diabetes, Bryan Cruz
Open Access Theses & Dissertations
This study examined whether the strong reinforcing effects of nicotine and changes in insulin biomarkers observed in diabetic rats are modulated via insulin. A model of diabetes was employed involving administration of streptozotocin (STZ), which produces hypoinsulinemia in rats. The present study included vehicle- or STZ-treated rats that received sham surgery or an insulin pellet. Two-weeks later, the rats were given extended access to intravenous self-administration (IVSA) of saline or nicotine. Concomitant changes in food intake, water responses, and body weight were assessed during 12 days of IVSA. After the last session, plasma levels of insulin, leptin, amylin, and glucagon-like …