Experimental Analysis of Behavior Commons^™

Dose-Related Sex Differences In The Establishment Of Conditioned Disgust (Anticipatory Nausea), And The Effect Of Peripubertal And Adult Immune System Stimulation With The Endotoxin Lipopolysaccharide (Lps) On Learning And Memory In The Rat, Caylen J. Cloutier

Electronic Thesis and Dissertation Repository

This thesis examined sex differences in the establishment of lithium chloride (LiCl) – induced conditioned disgust behavior (anticipatory nausea) to a distinct context, as well as, the establishment of conditioned place avoidance (CPA) using rodent models. Also examined were potential sex differences in response to treatment with the bacterial endotoxin, lipopolysaccharide (LPS), and its effect on learning and memory. In Chapter 2, male and female naïve Long-Evans rats were injected (intraperitoneally; i.p.) with either 200 µg/kg LPS or 0.9% (NaCl), 90 minutes prior to i.p. injections of either 128 mg/kg LiCl or 0.9% NaCl, and immediately placed into a distinctive …