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Experimental Analysis of Behavior Commons™
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Full-Text Articles in Experimental Analysis of Behavior
An Investigation Of Short-Term Memory Functioning In A Neurodevelopmental Rat Model Of Schizophrenia, Ashley M. Moyett
An Investigation Of Short-Term Memory Functioning In A Neurodevelopmental Rat Model Of Schizophrenia, Ashley M. Moyett
Seton Hall University Dissertations and Theses (ETDs)
Schizophrenia is a debilitating disorder characterized by positive, negative, and cognitive symptoms. Cognitive deficits affect one’s learning and memory due to a dysfunction in the brain, inhibiting a normal functioning life. The self-medicating hypothesis states that ninety percent of people with schizophrenia smoke, because nicotine use improves these cognitive deficits. The cytokine hypothesis states that inflammation due to prenatal infection is associated with schizophrenia. These increased proinflamatory cytokines can damage the brains of the fetuses, which can cause schizophrenic-like symptoms in rats. The present study used Lipopolysaccharides to activate the cytokine-mediated inflammatory response injected into pregnant dams. A T-maze was …
Environmental- And Ethanol-Induced Effects On Reference And Short-Term Memory In The Rat, Kimberly Ramos
Environmental- And Ethanol-Induced Effects On Reference And Short-Term Memory In The Rat, Kimberly Ramos
Seton Hall University Dissertations and Theses (ETDs)
Environmental enrichment (EE) is a combination of complex physical and social stimulation beyond that which would be received in standard or isolated laboratory housing. Continuous enrichment paradigms have been shown, among other influences, to increase neurogenesis and dendritic branching, and enhance learning and memory. Recently, the preventative effects of enrichment have been considered, specifically relating to drugs of abuse (Solinas, Thiret, Chauvet, & Jaber 2010; Stairs & Bardo 2009). This series of studies examined the effects of daily EE on reference memory and short-term memory, as assessed in the radial arm water maze (RAWM) and Morris water maze (MWM). Sprague-Dawley …