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Experimental Analysis of Behavior Commons

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Seton Hall University

Alcohol

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Differences In Compulsive-Like Ethanol Consumption In Adolescent-Trained And Adult-Trained Rats Exposed To Acute Isolation Stressors, Maria J. Lopez Aug 2021

Differences In Compulsive-Like Ethanol Consumption In Adolescent-Trained And Adult-Trained Rats Exposed To Acute Isolation Stressors, Maria J. Lopez

Seton Hall University Dissertations and Theses (ETDs)

The Pavlovian Conditioned Approach (PCA) procedure is an experimental procedure used with animals to induce compulsive-like behaviors directed towards an object conditioned stimulus (CS) paired with a sucrose pellet unconditioned stimulus (US) presented in a nearby food tray (sign tracking). When the object CS is an alcohol-containing bottle, the rats demonstrate compulsive-like interactions with the bottle object (e.g., approach, contact, and licking) that also results in alcohol consumption (drinking) in most rats. Compulsive alcohol drinking in a sign-tracking procedure is a result of the combined effects of schedule-induced compulsive-like behavior and the intake of alcohol (Tomie & Sharma, 2013).

The …