Open Access. Powered by Scholars. Published by Universities.®

Counseling Psychology Commons

Open Access. Powered by Scholars. Published by Universities.®

University of Louisville

Cross-sectional study

Publication Year

Articles 1 - 2 of 2

Full-Text Articles in Counseling Psychology

Do Depressive Symptoms Mediate The Relationship Between Hopelessness And Diurnal Cortisol Rhythm?, Patrick Pössel, Amanda M. Mitchell, Elaine Sjögren, Margareta Kristenson Apr 2015

Do Depressive Symptoms Mediate The Relationship Between Hopelessness And Diurnal Cortisol Rhythm?, Patrick Pössel, Amanda M. Mitchell, Elaine Sjögren, Margareta Kristenson

Faculty Scholarship

Purpose: Research has revealed a well-established relationship of depressive symptoms and hopelessness with a variety of physical illnesses that are associated with a dysfunction of the hypothalamic-pituitary-adrenal-axis. The purpose of this study was to test if depressive symptoms mediate the relationship between hopelessness and cortisol, a measure of the hypothalamic-pituitary-adrenal-axis. Methods: Hopelessness, depressive symptoms, and diurnal cortisol rhythm were measured in 257 adults (128 women and 129 men; age range: 20-74 years) in this cross-sectional study. To test the hypothesis, two linear regression analyses and asymmetrical confidence intervals around the regression weights were conducted. A second set of analyses was …


Hopelessness The ‘Active Ingredient’? : Associations Of Hopelessness And Depressive Symptoms With Interleukin-6., Amanda M. Mitchell, Patrick Pössel, Elaine Sjögren, Margareta Kristenson Nov 2013

Hopelessness The ‘Active Ingredient’? : Associations Of Hopelessness And Depressive Symptoms With Interleukin-6., Amanda M. Mitchell, Patrick Pössel, Elaine Sjögren, Margareta Kristenson

Faculty Scholarship

Objective: Previous research has revealed a relationship of depressive symptoms and hopelessness with cardiovascular diseases (CVDs) which are associated with elevated levels of interleukin-6 (IL-6). The objective of this study was to explore whether depressive symptoms and hopelessness are independent predictors of IL-6 levels. Method: Hopelessness, depressive symptoms, and IL-6 were measured in 45 Swedish adults (26 women and 19 men; age range: 31-65 years). Two separated linear regressions were conducted with hopelessness and depressive symptoms serving as individual predictors of IL-6. Another regression analysis examined whether the two predictors predict IL-6 when controlling for each other. The regression coefficients …