Cognitive Psychology Commons^™

Withdrawal From Voluntary Oral Methamphetamine Reveals Female Specific Susceptibilities To Behavioral Deficits And Neurochemical Perpetuators Of Neurotoxicity And Drug Seeking Behavior, Nicoletta K. Memos

Dissertations, Theses, and Capstone Projects

MA is a potent, highly addictive psychomotor stimulant known to produce neurotoxic effects on the brain leading to neurological impairments^1-6 characterized by neurodegeneration of dopaminergic fibers, cell bodies and pathways, as well as brain regions such as the hippocampus, frontal cortex, and midbrain^1,5.

In MA addiction, women are more vulnerable to the behavioral and cognitive effects of MA compared to men. Adult human literature reveals gender differences in usage patterns and women demonstrate increased vulnerability to the neurotoxic effects and health effects of MA use. Women begin drug use at an earlier age, escalate drug use quicker, …

Individual Differences In Coping With Large Multimodal Conflicts In A Spatial Orientation Paradigm, Cassandra J. Engstrom

Dissertations, Theses, and Capstone Projects

This study examined how humans respond to large 180º disparities between internally generated self-motion cues and external landmarks in a navigation task. Subjects learned the locations of 4 objects in a virtual environment, navigating back to these sites in a testing phase that probed their sense of direction at dead-ends. In select (incongruent) trials, subjects’ virtual rotations were mirrored relative to their physical turns, forcing them to navigate along separate virtual and physical trajectories. On these trials, subjects were either instructed to navigate using their memory of the required turn sequence (proprioceptive instructions) or the external environment (visual …