Clinical Psychology Commons^™

Clarifying The Influence Of Comorbid Depression On Response Inhibition In Obsessive-Compulsive Disorder And Trichotillomania, Gregory Berlin

Theses and Dissertations

Response inhibition performance in Obsessive-Compulsive and Related Disorders (OCRDs) is emerging as a potential neurocognitive endophenotype of these disorders. A point of needed clarification, however, is how unique such performance is to the OCRD spectrum. Specifically, it is unknown whether comorbid depression, a disorder that frequently occurs with OCRDs (60-80%) (Pallanti et al., 2011) and is also associated with cognitive deficits, can influence response inhibition observed in OCRDs. We sought to clarify whether response inhibition performance could be reliably accounted for OCRD symptomology (in obsessive compulsive disorder and trichotillomania specifically) even when taking into consideration the influence of comorbid depression. …