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Full-Text Articles in Clinical Psychology
Apoe Risk Disclosure: A Review Of Positive And Negative Outcome, Stacey Rowcliffe
Apoe Risk Disclosure: A Review Of Positive And Negative Outcome, Stacey Rowcliffe
Dissertations
Two of this century’s most significant healthcare challenges are Alzheimer’s disease and mild cognitive impairment, with 40 million people suffering from the diseases. In fact, a conservative estimate projects that both conditions will double every 20 years until 2050. Alzheimer’s disease involves memory impairment, disorientation, confusion, and various problematic behaviors. Presently, no prevention method or cure has been discovered for Alzheimer’s. Mild cognitive impairment typically includes problems with memory, language, thinking, and judgment beyond those typical of one’s age. Usually, these symptoms do not interfere with daily activities but do not improve and have been linked with a risk of …
The Relationship Between Neuropsychological Functioning, Biomarker Av-1451, And Subjective Memory Impairment In A Cognitively Normal Sample, Amberrose Reale-Caldwell
The Relationship Between Neuropsychological Functioning, Biomarker Av-1451, And Subjective Memory Impairment In A Cognitively Normal Sample, Amberrose Reale-Caldwell
Dissertations
Mild cognitive impairment (MCI) is often a prodromal stage for Alzheimer’s disease (AD) development, with those diagnosed with MCI at increased risk for developing AD. The present study aimed to provide data to support a prodromal stage of MCI via analysis utilizing the neuropsychological domain of memory, subjective memory impairment (SMI), and the PET tau biomarker, AV-1451. It was hypothesized that individuals with SMI would differ significantly from participants without SMI (nSMI) on measures of memory and level of tau binding in the entorhinal cortices and the hippocampi. It was further hypothesized that differences in memory would be mediated by …