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Full-Text Articles in Psychology

Glucose Modulation Of The Septo-Hippocampal System: Implications For Memory, Desiree Lynne Krebs-Kraft Dec 2006

Glucose Modulation Of The Septo-Hippocampal System: Implications For Memory, Desiree Lynne Krebs-Kraft

Psychology Dissertations

Extensive evidence suggests that glucose has both positive and negative effects on memory and these effects likely involve an influence on the brain. For instance, direct infusions of glucose into the septum (MS) or hippocampus can enhance or impair memory. The present set of experiments attempted to determine the different conditions that dissociate the memory-enhancing and -impairing effects of glucose in rats. Specifically, these experiments examined the effects of glucose in spontaneous alternation, a measure of spatial working memory and shock avoidance, an index of emontional long-term memory. The results showed that the memory-impairing effects of MS infusions of glucose …


Activation Of Brain Regions Vulnerable To Alzheimer's Disease: The Effect Of Mild Cognitive Impairment, S. C. Johnson, T. W. Schmitz, C. H. Moritz, M. E. Meyerand, H. A. Rowley, A. L. Alexander, K. W. Hansen, C. E. Gleason, C. M. Carlsson, M. L. Ries, S. Asthana, K. Chen, E. M. Reiman, G. E. Alexander Nov 2006

Activation Of Brain Regions Vulnerable To Alzheimer's Disease: The Effect Of Mild Cognitive Impairment, S. C. Johnson, T. W. Schmitz, C. H. Moritz, M. E. Meyerand, H. A. Rowley, A. L. Alexander, K. W. Hansen, C. E. Gleason, C. M. Carlsson, M. L. Ries, S. Asthana, K. Chen, E. M. Reiman, G. E. Alexander

Brain and Mind Institute Researchers' Publications

This study examined the functionality of the medial temporal lobe (MTL) and posterior cingulate (PC) in mild cognitive impairment amnestic type (MCI), a syndrome that puts patients at greater risk for developing Alzheimer disease (AD). Functional MRI (fMRI) was used to identify regions normally active during encoding of novel items and recognition of previously learned items in a reference group of 77 healthy young and middle-aged adults. The pattern of activation in this group guided further comparisons between 14 MCI subjects and 14 age-matched controls. The MCI patients exhibited less activity in the PC during recognition of previously learned items, …


Verbal Learning And Memory Abilities In Children With Brain Tumors: The Role Of The Third Ventricle Region, Jackie L. Micklewright Jan 2006

Verbal Learning And Memory Abilities In Children With Brain Tumors: The Role Of The Third Ventricle Region, Jackie L. Micklewright

Psychology Theses

The third ventricle region houses several neuroanatomical structures that are primary components of the human memory system, and provides pathways through which these brain regions communicate with critical regions of the frontal and medial temporal lobes. Archival data was obtained for 42 children with cerebellar or third ventricle tumors, and was examined for tumor and treatment related confounds. Children with third ventricle tumors were hypothesized to exhibit; 1) better performance on a measure of auditory attention, 2) greater impairment in learning across trials, 3) greater memory loss over a 20-minute delay, and 4) greater impairment across delayed memory tests than …


The Effect Of Substance P On Ovariectomy-Induced Memory Deficits In Rats, Jamie L. Haga Jan 2006

The Effect Of Substance P On Ovariectomy-Induced Memory Deficits In Rats, Jamie L. Haga

Theses, Dissertations and Capstones

The present experiment was designed to test whether pretreatment with substance P would affect ovariectomy-induced memory deficits in rats for retention in the Morris water maze. Adult female Sprague-Dawley rats were divided to two groups: (1) control (received saline) and (2) experimental group (received substance P). All rats underwent an ovariectomy, as this has been shown to significantly impair spatial reference learning and memory (Monteiro, Matté, Bavaresco, Netto, & Wyse, 2005). Approximately 8 months after surgery, all rats were trained in the Morris water maze in order to evaluate both reference and working memory. Results showed that substance P did …